NZ333083A - Antibodies to the ED-B domain of fibronectin (FN), their construction and uses - Google Patents

Antibodies to the ED-B domain of fibronectin (FN), their construction and uses

Info

Publication number
NZ333083A
NZ333083A NZ33308397A NZ33308397A NZ333083A NZ 333083 A NZ333083 A NZ 333083A NZ 33308397 A NZ33308397 A NZ 33308397A NZ 33308397 A NZ33308397 A NZ 33308397A NZ 333083 A NZ333083 A NZ 333083A
Authority
NZ
New Zealand
Prior art keywords
specific binding
fibronectin
library
binding member
clones
Prior art date
Application number
NZ33308397A
Other languages
English (en)
Inventor
Dario Neri
Barbara Carnemolla
Annalisa Siri
Enrica Balza
Patrizia Castellani
Alessandro Pini
Luciano Zardi
Greg Winter
Giovanni Neri
Laura Borsi
Original Assignee
Philogen Societa Responsibilit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philogen Societa Responsibilit filed Critical Philogen Societa Responsibilit
Publication of NZ333083A publication Critical patent/NZ333083A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
NZ33308397A 1996-05-24 1997-05-23 Antibodies to the ED-B domain of fibronectin (FN), their construction and uses NZ333083A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9610967A GB9610967D0 (en) 1996-05-24 1996-05-24 Specific binding members,materials and methods
PCT/GB1997/001412 WO1997045544A1 (en) 1996-05-24 1997-05-23 Antibodies to the ed-b domain of fibronectin, their construction and uses

Publications (1)

Publication Number Publication Date
NZ333083A true NZ333083A (en) 2000-05-26

Family

ID=10794298

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ33308397A NZ333083A (en) 1996-05-24 1997-05-23 Antibodies to the ED-B domain of fibronectin (FN), their construction and uses

Country Status (28)

Country Link
US (3) US7273924B1 (enExample)
EP (1) EP0906426B1 (enExample)
JP (2) JP4750912B2 (enExample)
KR (2) KR100741452B1 (enExample)
CN (1) CN100447159C (enExample)
AT (1) ATE361364T1 (enExample)
AU (1) AU729081B2 (enExample)
BG (1) BG65138B1 (enExample)
BR (1) BR9709350B1 (enExample)
CA (1) CA2256308C (enExample)
CZ (1) CZ295531B6 (enExample)
DE (1) DE69737683T2 (enExample)
DK (1) DK0906426T3 (enExample)
EA (1) EA004329B1 (enExample)
ES (1) ES2286831T3 (enExample)
GB (1) GB9610967D0 (enExample)
HU (1) HUP0200546A2 (enExample)
IL (2) IL127216A0 (enExample)
IS (1) IS2508B (enExample)
NO (1) NO324904B1 (enExample)
NZ (1) NZ333083A (enExample)
PL (1) PL188557B1 (enExample)
PT (1) PT906426E (enExample)
SI (1) SI0906426T1 (enExample)
SK (1) SK285916B6 (enExample)
TR (1) TR199802416T2 (enExample)
UA (1) UA74129C2 (enExample)
WO (1) WO1997045544A1 (enExample)

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CN111148759B (zh) * 2017-09-30 2023-09-19 合肥立方制药股份有限公司 结合至纤维连接蛋白b结构域的蛋白
WO2019091918A1 (en) 2017-11-07 2019-05-16 Navigo Proteins Gmbh Fusion proteins with specificity for ed-b and long serum half-life for diagnosis or treatment of cancer
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WO2020070150A1 (en) 2018-10-02 2020-04-09 Philogen S.P.A Il2 immunoconjugates
JP2022544760A (ja) 2019-08-15 2022-10-21 ヤンセン バイオテツク，インコーポレーテツド 改善された単鎖可変断片のための材料及び方法
WO2021116337A1 (en) 2019-12-11 2021-06-17 Cilag Gmbh International Multispecific binding molecules comprising ltbr and edb binding domains and uses thereof
CN111234016B (zh) * 2020-02-23 2021-09-07 北京康普美特创新医药科技有限责任公司 一种抗补体c5分子的全人源单克隆抗体及应用
CN111171149B (zh) * 2020-02-23 2021-09-07 北京康普美特创新医药科技有限责任公司 一种抗补体c5分子的人源化单链抗体及其应用
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Also Published As

Publication number Publication date
SK285916B6 (sk) 2007-11-02
US20080274099A1 (en) 2008-11-06
ATE361364T1 (de) 2007-05-15
JP4750912B2 (ja) 2011-08-17
CZ381598A3 (cs) 1999-03-17
UA74129C2 (uk) 2005-11-15
EP0906426B1 (en) 2007-05-02
AU2910197A (en) 1998-01-05
CN1219968A (zh) 1999-06-16
SK161298A3 (en) 1999-07-12
BG65138B1 (bg) 2007-03-30
AU729081B2 (en) 2001-01-25
EP0906426A1 (en) 1999-04-07
TR199802416T2 (xx) 1999-02-22
IL127216A (en) 2008-11-26
DK0906426T3 (da) 2007-09-10
PL330075A1 (en) 1999-04-26
ES2286831T3 (es) 2007-12-01
CZ295531B6 (cs) 2005-08-17
SI0906426T1 (sl) 2007-10-31
CA2256308C (en) 2012-03-13
BG102950A (en) 1999-08-31
US7273924B1 (en) 2007-09-25
EA004329B1 (ru) 2004-04-29
KR20050010081A (ko) 2005-01-26
IL127216A0 (en) 1999-09-22
CN100447159C (zh) 2008-12-31
JP2000511416A (ja) 2000-09-05
DE69737683T2 (de) 2008-01-10
US20140134182A1 (en) 2014-05-15
US9096670B2 (en) 2015-08-04
KR20060035812A (ko) 2006-04-26
BR9709350A (pt) 2000-01-04
IS4883A (is) 1998-10-29
WO1997045544A1 (en) 1997-12-04
PT906426E (pt) 2007-07-23
US8703143B2 (en) 2014-04-22
JP2009050261A (ja) 2009-03-12
HUP0200546A2 (en) 2002-07-29
NO985459L (no) 1999-01-22
BR9709350B1 (pt) 2010-12-14
DE69737683D1 (de) 2007-06-14
PL188557B1 (pl) 2005-02-28
KR100741452B1 (ko) 2007-07-20
IS2508B (is) 2009-04-15
GB9610967D0 (en) 1996-07-31
HK1020990A1 (zh) 2000-05-26
CA2256308A1 (en) 1997-12-04
EA199801043A1 (ru) 1999-04-29
NO985459D0 (no) 1998-11-23
NO324904B1 (no) 2007-12-27

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