IS4883A - Mótefni gegn ED-B hneppinu í fíbrónektíni, smíði þeirra og notkanir - Google Patents

Mótefni gegn ED-B hneppinu í fíbrónektíni, smíði þeirra og notkanir

Info

Publication number
IS4883A
IS4883A IS4883A IS4883A IS4883A IS 4883 A IS4883 A IS 4883A IS 4883 A IS4883 A IS 4883A IS 4883 A IS4883 A IS 4883A IS 4883 A IS4883 A IS 4883A
Authority
IS
Iceland
Prior art keywords
fibronectin
antibodies
box
construction
specific
Prior art date
Application number
IS4883A
Other languages
English (en)
Other versions
IS2508B (is
Inventor
Carnemolla Barbara
Siri Annalisa
Balza Enrica
Castellani Patrizia
Zardi Luciano
Borsi Laura
Neri Dario
Winter Greg
Pini Alessandro
Neri Giovanni
Original Assignee
Philogen S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philogen S.R.L. filed Critical Philogen S.R.L.
Publication of IS4883A publication Critical patent/IS4883A/is
Publication of IS2508B publication Critical patent/IS2508B/is

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
IS4883A 1996-05-24 1998-10-29 Mótefni gegn ED-B hneppinu í fíbrónektíni, smíði þeirra og notkanir IS2508B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9610967A GB9610967D0 (en) 1996-05-24 1996-05-24 Specific binding members,materials and methods
PCT/GB1997/001412 WO1997045544A1 (en) 1996-05-24 1997-05-23 Antibodies to the ed-b domain of fibronectin, their construction and uses

Publications (2)

Publication Number Publication Date
IS4883A true IS4883A (is) 1998-10-29
IS2508B IS2508B (is) 2009-04-15

Family

ID=10794298

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4883A IS2508B (is) 1996-05-24 1998-10-29 Mótefni gegn ED-B hneppinu í fíbrónektíni, smíði þeirra og notkanir

Country Status (29)

Country Link
US (3) US7273924B1 (is)
EP (1) EP0906426B1 (is)
JP (2) JP4750912B2 (is)
KR (2) KR100741452B1 (is)
CN (1) CN100447159C (is)
AT (1) ATE361364T1 (is)
AU (1) AU729081B2 (is)
BG (1) BG65138B1 (is)
BR (1) BR9709350B1 (is)
CA (1) CA2256308C (is)
CZ (1) CZ295531B6 (is)
DE (1) DE69737683T2 (is)
DK (1) DK0906426T3 (is)
EA (1) EA004329B1 (is)
ES (1) ES2286831T3 (is)
GB (1) GB9610967D0 (is)
HK (1) HK1020990A1 (is)
HU (1) HUP0200546A2 (is)
IL (2) IL127216A0 (is)
IS (1) IS2508B (is)
NO (1) NO324904B1 (is)
NZ (1) NZ333083A (is)
PL (1) PL188557B1 (is)
PT (1) PT906426E (is)
SI (1) SI0906426T1 (is)
SK (1) SK285916B6 (is)
TR (1) TR199802416T2 (is)
UA (1) UA74129C2 (is)
WO (1) WO1997045544A1 (is)

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US11414466B2 (en) 2017-11-07 2022-08-16 Navigo Proteins Gmbh Fusion proteins with specificity for ED-B and long serum half-life for diagnosis or treatment of cancer
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KR20220130687A (ko) 2019-12-11 2022-09-27 시락 게엠베하 인터내셔날 Ltbr 및 edb 결합 도메인을 포함하는 다중특이성 결합 분자 및 이의 용도
CN111171149B (zh) * 2020-02-23 2021-09-07 北京康普美特创新医药科技有限责任公司 一种抗补体c5分子的人源化单链抗体及其应用
CN111234016B (zh) * 2020-02-23 2021-09-07 北京康普美特创新医药科技有限责任公司 一种抗补体c5分子的全人源单克隆抗体及应用
KR102614063B1 (ko) 2020-12-24 2023-12-19 대화제약 주식회사 엑스트라도메인 b 피브로넥틴에 특이적으로 결합하는 신규한 항체
WO2023131611A1 (en) 2022-01-04 2023-07-13 Philogen S.P.A. Combination of an immunocytokine comprising il-12 and a kinase inhibitor
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Also Published As

Publication number Publication date
US9096670B2 (en) 2015-08-04
CZ381598A3 (cs) 1999-03-17
PT906426E (pt) 2007-07-23
BR9709350A (pt) 2000-01-04
CA2256308A1 (en) 1997-12-04
CA2256308C (en) 2012-03-13
ATE361364T1 (de) 2007-05-15
CN100447159C (zh) 2008-12-31
JP2009050261A (ja) 2009-03-12
US20140134182A1 (en) 2014-05-15
EA199801043A1 (ru) 1999-04-29
KR100741452B1 (ko) 2007-07-20
JP2000511416A (ja) 2000-09-05
KR20050010081A (ko) 2005-01-26
HK1020990A1 (en) 2000-05-26
JP4750912B2 (ja) 2011-08-17
ES2286831T3 (es) 2007-12-01
SK161298A3 (en) 1999-07-12
CZ295531B6 (cs) 2005-08-17
GB9610967D0 (en) 1996-07-31
EA004329B1 (ru) 2004-04-29
IL127216A0 (en) 1999-09-22
KR20060035812A (ko) 2006-04-26
AU729081B2 (en) 2001-01-25
HUP0200546A2 (en) 2002-07-29
IS2508B (is) 2009-04-15
NZ333083A (en) 2000-05-26
EP0906426A1 (en) 1999-04-07
US8703143B2 (en) 2014-04-22
NO985459L (no) 1999-01-22
SK285916B6 (sk) 2007-11-02
US7273924B1 (en) 2007-09-25
SI0906426T1 (sl) 2007-10-31
UA74129C2 (uk) 2005-11-15
BG102950A (en) 1999-08-31
BR9709350B1 (pt) 2010-12-14
IL127216A (en) 2008-11-26
NO324904B1 (no) 2007-12-27
DE69737683T2 (de) 2008-01-10
TR199802416T2 (xx) 1999-02-22
PL330075A1 (en) 1999-04-26
NO985459D0 (no) 1998-11-23
PL188557B1 (pl) 2005-02-28
EP0906426B1 (en) 2007-05-02
CN1219968A (zh) 1999-06-16
DE69737683D1 (de) 2007-06-14
US20080274099A1 (en) 2008-11-06
AU2910197A (en) 1998-01-05
WO1997045544A1 (en) 1997-12-04
DK0906426T3 (da) 2007-09-10
BG65138B1 (bg) 2007-03-30

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