IT1217724B - Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori - Google Patents

Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori

Info

Publication number
IT1217724B
IT1217724B IT20741/88A IT2074188A IT1217724B IT 1217724 B IT1217724 B IT 1217724B IT 20741/88 A IT20741/88 A IT 20741/88A IT 2074188 A IT2074188 A IT 2074188A IT 1217724 B IT1217724 B IT 1217724B
Authority
IT
Italy
Prior art keywords
monoclonal antibody
antibody
tumors
diagnosis
sequence
Prior art date
Application number
IT20741/88A
Other languages
English (en)
Other versions
IT8820741A0 (it
Inventor
Luciano Zardi
Original Assignee
Ist Naz Ric Sul Cancro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ist Naz Ric Sul Cancro filed Critical Ist Naz Ric Sul Cancro
Priority to IT20741/88A priority Critical patent/IT1217724B/it
Publication of IT8820741A0 publication Critical patent/IT8820741A0/it
Priority to EP89830234A priority patent/EP0344134B1/en
Priority to AT89830234T priority patent/ATE100471T1/de
Priority to DE89830234T priority patent/DE68912403T2/de
Application granted granted Critical
Publication of IT1217724B publication Critical patent/IT1217724B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT20741/88A 1988-05-26 1988-05-26 Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori IT1217724B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT20741/88A IT1217724B (it) 1988-05-26 1988-05-26 Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori
EP89830234A EP0344134B1 (en) 1988-05-26 1989-05-25 Monoclonal antibody specific to a fibronectin sequence expressed in transformed cells, hybridoma secreting said antibody and use of said monoclonal antibody in the diagnosis of tumors
AT89830234T ATE100471T1 (de) 1988-05-26 1989-05-25 Monoklonaler antikoerper, spezifisch fuer eine in transformierten zellen exprimierte fibronectinsequenz, hybridoma, das diesen antikoerper erzeugt und verwendung dieses monoklonalen antikoerpers zur diagnose von tumoren.
DE89830234T DE68912403T2 (de) 1988-05-26 1989-05-25 Monoklonaler Antikörper, spezifisch für eine in transformierten Zellen exprimierte Fibronectin-Sequenz, Hybridoma, das diesen Antikörper erzeugt und Verwendung dieses monoklonalen Antikörpers zur Diagnose von Tumoren.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20741/88A IT1217724B (it) 1988-05-26 1988-05-26 Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori

Publications (2)

Publication Number Publication Date
IT8820741A0 IT8820741A0 (it) 1988-05-26
IT1217724B true IT1217724B (it) 1990-03-30

Family

ID=11171367

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20741/88A IT1217724B (it) 1988-05-26 1988-05-26 Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori

Country Status (4)

Country Link
EP (1) EP0344134B1 (it)
AT (1) ATE100471T1 (it)
DE (1) DE68912403T2 (it)
IT (1) IT1217724B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI892197A (fi) * 1989-05-08 1990-11-09 Locus Oy Foerfarande foer detektering av tumoerer.
EP0522086B1 (en) * 1990-03-12 1994-07-20 The Biomembrane Institute DNA SEQUENCE ENCODING GALACTOPROTEIN b3
GB9610967D0 (en) 1996-05-24 1996-07-31 Cambridge Antibody Tech Specific binding members,materials and methods
DK1037927T3 (da) 1997-12-08 2004-09-06 Emd Lexigen Res Ct Corp Heterodimere fusionsproteiner, der er nyttige til målrettet immunterapi og generel immunstimulering
GB9726539D0 (en) 1997-12-16 1998-02-11 Univ Dundee Polypeptides, polynucleotides and uses thereof
AU4314801A (en) 2000-02-11 2001-08-20 Lexigen Pharm Corp Enhancing the circulating half-life of antibody-based fusion proteins
CA2400622A1 (en) 2000-02-24 2001-08-30 Eidgenossische Technische Hochschule Zurich Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis
ATE526039T1 (de) 2000-02-24 2011-10-15 Philogen Spa Zusammensetzungen und verfahren zur behandlung von angiogenese in pathologischen schädigungen
WO2002072605A2 (en) 2001-03-07 2002-09-19 Merck Patent Gmbh Expression technology for proteins containing a hybrid isotype antibody moiety
WO2002090566A2 (en) 2001-05-03 2002-11-14 Merck Patent Gmbh Recombinant tumor specific antibody and use thereof
BR0214650A (pt) 2001-12-04 2005-05-03 Merck Patent Gmbh Imunocitoquinas com seletividade modulada
CA2552590A1 (en) 2004-01-05 2005-07-21 Emd Lexigen Research Center Corp. Interleukin-12 targeted to oncofoetal fibronectin
CA2553883C (en) 2004-01-22 2013-04-02 Merck Patent Gesellschaft Mit Beschraenkter Haftung Anti-cancer antibodies with reduced complement fixation
US7785591B2 (en) 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
DK2270050T3 (da) 2005-12-30 2013-08-12 Merck Patent Gmbh Anti-CD19-antistoffer med nedsat immunogenicitet
ES2609813T3 (es) 2007-04-02 2017-04-24 Philogen S.P.A. Antígeno nuevo asociado con la neovasculatura de metástasis tumorales
US10202442B2 (en) 2007-07-25 2019-02-12 Philogen S.P.A. Antigen associated with lung cancers and lymphomas
DK2209805T3 (en) 2007-10-30 2017-10-16 Philogen Spa Antigen associated with rheumatoid arthritis
EP2100621A1 (en) 2008-03-10 2009-09-16 mivenion GmbH Polyether polyol dendron conjugates with effector molecules for biological targeting
ES2640981T3 (es) 2009-08-05 2017-11-07 Philogen S.P.A. Selección como diana de neovasculatura de médula ósea
SI2903629T1 (sl) 2012-10-03 2019-09-30 Philogen S.P.A. Konjugat protitelesa za uporabo pri zdravljenju vnetnih črevesnih bolezni

Also Published As

Publication number Publication date
DE68912403T2 (de) 1994-05-11
EP0344134A2 (en) 1989-11-29
DE68912403D1 (de) 1994-03-03
EP0344134A3 (en) 1990-08-08
ATE100471T1 (de) 1994-02-15
IT8820741A0 (it) 1988-05-26
EP0344134B1 (en) 1994-01-19

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