NZ211030A - Passive heterologous immunisation compositions based on antibodies from pre-immunised fowls and/or bovids - Google Patents
Passive heterologous immunisation compositions based on antibodies from pre-immunised fowls and/or bovidsInfo
- Publication number
- NZ211030A NZ211030A NZ211030A NZ21103085A NZ211030A NZ 211030 A NZ211030 A NZ 211030A NZ 211030 A NZ211030 A NZ 211030A NZ 21103085 A NZ21103085 A NZ 21103085A NZ 211030 A NZ211030 A NZ 211030A
- Authority
- NZ
- New Zealand
- Prior art keywords
- antibody
- antigen
- bovid
- milk
- fowl
- Prior art date
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/04—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from milk
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/02—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from eggs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/23—Immunoglobulins specific features characterized by taxonomic origin from birds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Dairy Products (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57780484A | 1984-02-07 | 1984-02-07 | |
| US06/622,130 US4748018A (en) | 1984-02-07 | 1984-06-19 | Method of passive immunization of mammals using avian antibody |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ211030A true NZ211030A (en) | 1989-11-28 |
Family
ID=27077340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ211030A NZ211030A (en) | 1984-02-07 | 1985-02-04 | Passive heterologous immunisation compositions based on antibodies from pre-immunised fowls and/or bovids |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4748018A (forum.php) |
| EP (2) | EP0395120B1 (forum.php) |
| JP (6) | JP2548115B2 (forum.php) |
| AT (1) | ATE135016T1 (forum.php) |
| CA (3) | CA1275044A (forum.php) |
| DE (1) | DE3504221C2 (forum.php) |
| DK (2) | DK166905B1 (forum.php) |
| GR (1) | GR850323B (forum.php) |
| HK (1) | HK1000183A1 (forum.php) |
| IE (1) | IE64365B1 (forum.php) |
| IL (1) | IL74155A (forum.php) |
| NZ (1) | NZ211030A (forum.php) |
Families Citing this family (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4824432A (en) * | 1981-03-24 | 1989-04-25 | S.V.S. Laboratories, Inc. | Method for treating AIDS and other immune deficiencies and immune disorders |
| US5932250A (en) * | 1982-06-03 | 1999-08-03 | Dcv, Inc. | Anti-cholesterolemic egg, vaccine and method for production, and use |
| US5130128A (en) * | 1982-06-03 | 1992-07-14 | Stolle Research & Development Corporation | Use of honey as vaccine |
| EP0225254B1 (en) * | 1985-11-25 | 1994-03-16 | Ghen Corporation | Specific antibody-containing substance from eggs and method of production and use thereof |
| CA1336818C (en) * | 1987-04-16 | 1995-08-29 | International Institute Of Cellular And Molecular Pathology | Treatment of allergy and composition thereof |
| US5284931A (en) * | 1987-05-04 | 1994-02-08 | Dana Farber Cancer Institute | Intercellular adhesion molecules, and their binding ligands |
| US5565550A (en) * | 1987-05-04 | 1996-10-15 | Dana Farber Cancer Institute | Antibodies to ICAM-2, and fragments thereof |
| JP2641228B2 (ja) * | 1988-01-22 | 1997-08-13 | 鐘紡株式会社 | 抗体およびそれを有効成分とするう蝕予防剤、並びにこれらの製造方法 |
| US5059419A (en) * | 1988-06-09 | 1991-10-22 | Grand Laboratories, Inc. | Streptococcus suis antiserum and its use in treating Streptococcus suis infections |
| JP2689511B2 (ja) * | 1988-08-18 | 1997-12-10 | ライオン株式会社 | 食 品 |
| US6511664B1 (en) | 1989-03-09 | 2003-01-28 | Dana Farber Cancer Institute | Intercellular adhesion molecule—2 and its binding ligands |
| DE3924746A1 (de) * | 1989-07-26 | 1991-01-31 | Behringwerke Ag | Erythropoietin (epo)-peptide und dagegen gerichtete antikoerper |
| US6932968B1 (en) | 1989-07-26 | 2005-08-23 | Dade Behring Marburg Gmbh | Erythropoietin (EPO) peptides and antibodies directed against these |
| US7005560B1 (en) * | 1989-10-27 | 2006-02-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
| US5196193A (en) * | 1989-10-31 | 1993-03-23 | Ophidian Pharmaceuticals, Inc. | Antivenoms and methods for making antivenoms |
| US5601823A (en) * | 1989-10-31 | 1997-02-11 | Ophidian Pharmaceuticals, Inc. | Avian antitoxins to clostridium difficle toxin A |
| US5958413A (en) * | 1990-11-01 | 1999-09-28 | Celltech Limited | Use of antibodies to TNF or fragments derived thereof and xanthine derivatives for combination therapy and compositions therefor |
| US5753228A (en) * | 1992-08-25 | 1998-05-19 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Method of treating parasitosis by the enteral administration of hyperimmune hen egg yolk antibodies |
| JP2553445B2 (ja) * | 1992-12-17 | 1996-11-13 | 同仁医薬化工株式会社 | 抗体の安定化方法 |
| DK0707485T3 (da) * | 1993-05-26 | 2002-08-26 | Dcv Inc | Cholesterolsænkende æg, vaccine og fremgangsmåde til fremstilling og anvendelse |
| US6068862A (en) * | 1993-06-30 | 2000-05-30 | Taiyo Kagaku Co., Ltd. | Tea-derived feed additive and animal feed containing the same |
| AU1518595A (en) * | 1994-01-14 | 1995-08-01 | Genentech Inc. | Antagonists to insulin receptor tyrosine kinase inhibitor |
| DE69535374T2 (de) | 1994-02-09 | 2007-08-23 | Epitopix Llc, Willmar | Aktive immunisierung gegen ein siderophores rezeptorprotein |
| US5830479A (en) * | 1994-02-09 | 1998-11-03 | Willmar Poultry Company, Inc. | Active immunization using a siderophore receptor protein |
| US5538733A (en) * | 1994-07-07 | 1996-07-23 | Willmar Poultry Company, Inc. | Method of priming an immune response in a one-day old animal |
| CA2196594A1 (en) * | 1994-08-05 | 1996-02-22 | Mark E. Cook | Use of antibodies to cck to improve feed efficiency |
| US5814316A (en) * | 1994-08-05 | 1998-09-29 | Wisconsin Alumni Research Foundation | Compound to mimick a naturally occurring peptide's effect |
| US5939269A (en) * | 1994-12-28 | 1999-08-17 | The Regents Of The University Of California | Antagonists to insulin receptor tyrosine kinase inhibitor |
| AU5431196A (en) * | 1995-03-24 | 1996-10-16 | Ophidian Pharmaceuticals | Treatment for verotoxin-producing escherichia coli |
| FI955389A0 (fi) * | 1995-11-09 | 1995-11-09 | Antti Sakari Aaltonen | Tandskyddande profylaktisk preparat och administreringsmedlen emot mellanoerpatogener |
| US6413515B1 (en) * | 1996-03-12 | 2002-07-02 | Ovogenix Immunpharma Gmbh | Avian, vitelline antibodies directed against HIV antigens |
| US5807551A (en) * | 1996-04-01 | 1998-09-15 | Iowa State University Research Foundation, Inc. | Method to provide artificial passive immunity in birds |
| US5725873A (en) * | 1996-07-22 | 1998-03-10 | Wisconsin Alumni Research Foundation | Method of improving the growth or the efficiency of feed conversion of an animal and compositions for use therein |
| US5772999A (en) * | 1996-07-30 | 1998-06-30 | Dcv Biologics, L.P. | Method of preventing, countering, or reducing NSAID-induced gastrointestinal damage by administering milk or egg products from hyperimmunized animals |
| EP0930891A4 (en) * | 1996-10-02 | 2001-07-04 | Ovimmune Inc | ORAL ADMINISTRATION OF CHICKEN EGG ANTIBODIES FOR TREATING DISEASES |
| JP3430853B2 (ja) * | 1997-04-11 | 2003-07-28 | 株式会社ゲン・コーポレーション | 胃炎、胃潰瘍および十二指腸潰瘍の予防剤並びに治療剤 |
| JPH10298105A (ja) * | 1997-04-23 | 1998-11-10 | Gen Corp:Kk | 腸管出血性大腸菌による感染症の予防剤および治療剤 |
| WO1998055143A1 (en) * | 1997-06-04 | 1998-12-10 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Lipid-reduced oral formulation for egg yolk-derived therapeutic protein |
| US6086878A (en) * | 1997-08-21 | 2000-07-11 | Dcv, Inc. | Method of increasing muscle protein and reducing fat in animals |
| CZ287956B6 (cs) * | 1997-11-04 | 2001-03-14 | Medipharm Cz, S. R. O. | Perorální přípravek k prevenci a léčbě parvovirózy psů |
| US6395273B1 (en) * | 1998-06-10 | 2002-05-28 | Promega Corporation | Prevention and treatment of inflammatory bowel disease |
| JP2000351735A (ja) * | 1999-04-09 | 2000-12-19 | Akzo Nobel Nv | カンピロバクターワクチン |
| US7238351B2 (en) * | 1999-07-15 | 2007-07-03 | Peter Nash | Immunogen adherence inhibitor directed to lactic acid producing organisms and method of making and using it |
| US7241443B1 (en) * | 1999-07-15 | 2007-07-10 | Camas Incorporated | Immunogen adherence inhibitor and method of making and using same |
| WO2001013928A1 (en) * | 1999-08-24 | 2001-03-01 | Ortho Corporation Co., Ltd. | Methods of pasteurizing immune substance containing antiinflammatory factor and utilization thereof |
| US6706267B1 (en) | 1999-09-14 | 2004-03-16 | Arkion Life Sciences Llc | Glucosamine and egg for reducing inflammation |
| GB0002386D0 (en) * | 2000-02-02 | 2000-03-22 | Novartis Nutrition Ag | Therapeutic composition |
| WO2001072141A2 (en) * | 2000-03-24 | 2001-10-04 | Trouw Nutrition Usa | Combination of plasma and hyperimmunized products for increased performance of weanlings |
| EP1353689B9 (en) * | 2001-01-03 | 2006-06-28 | Epitopix LLC | Immunizing compositions and methods of use |
| CA2339436A1 (fr) | 2001-03-15 | 2002-09-15 | Josee Harel | Production d'anticorps contre les facteurs de virulence associes aux souches d'escherichia coli aeec, et leur utilisation |
| US20030017154A1 (en) * | 2001-05-18 | 2003-01-23 | Hunchar Jeffrey G. | Method of increasing uniformity in avians |
| CA2392344A1 (en) * | 2001-07-02 | 2003-01-02 | Nutratech Inc. | Method for removal of pathogens from a localized environment |
| US6770280B1 (en) | 2001-11-15 | 2004-08-03 | Humanetics Corporation | Treatment of menorrhagia, hypermenorrhea, dysmenorrhea and menstrual migraines by the administration of an antibacterial milk product |
| EP1476184A4 (en) * | 2001-12-28 | 2006-01-04 | Camas Inc | IMMUNOGENOUS LIABILITY AND METHOD FOR ITS MANUFACTURE AND USE |
| KR100489615B1 (ko) * | 2002-01-30 | 2005-05-17 | 주식회사 단바이오텍 | 리스테리아 모노사이토제네스 감염의 예방 및 치료를 위한항체, 이를 포함하는 알 및 이들의 제조방법 |
| CA2474360A1 (en) * | 2002-02-11 | 2003-08-21 | Arkion Life Sciences Llc | Purified cytokine inhibitory factor |
| US20040005327A1 (en) * | 2002-05-16 | 2004-01-08 | Subramanian Iyer | Immune T-cell stimulation |
| US6729265B2 (en) * | 2002-06-27 | 2004-05-04 | Arkion Life Sciences Llc | Supplemented antibody feed to enter the circulating system of newborns |
| CN1819844B (zh) * | 2003-02-19 | 2012-02-22 | 彼得·纳什 | 免疫原粘附抑制剂及其制备和使用方法 |
| US9701737B2 (en) * | 2003-02-19 | 2017-07-11 | Camas, Incorporated | Immunogen adherence and method of making and using same |
| WO2005003173A1 (en) * | 2003-07-07 | 2005-01-13 | Luiz Fernando Mesquita | Process of obtaining a freeze-dried complex from mammal gland secretion |
| ES2395022T3 (es) | 2003-09-19 | 2013-02-07 | Epitopix, Llc | Polipéptidos de Campylobacter y sus métodos de uso |
| DE602005026287D1 (de) * | 2004-04-16 | 2011-03-24 | Univ Alberta | Anti-gluten-eigelb-antikörper zur behanldung von zoeliakie |
| US8877187B2 (en) * | 2005-07-25 | 2014-11-04 | Avianax, Llc | Therapeutic antibodies for treatment and prophylaxis of transmittable viral diseases |
| WO2007027321A2 (en) * | 2005-07-25 | 2007-03-08 | Avianax, Inc. | Therapeutic antibodies for treatment and prophylaxis of transmittable viral diseases |
| US20070264264A1 (en) * | 2005-08-30 | 2007-11-15 | La Belle Associates, Inc. | Method and composition for conferring immunity in mammals |
| CA2521156A1 (en) * | 2005-09-16 | 2007-03-16 | John Hare | Antibodies as growth promoting agents |
| EP1790358A1 (en) * | 2005-11-23 | 2007-05-30 | Université de Reims Champagne-Ardennes | Protein constructs designed for targeting and lysis of cells |
| EP1998800A2 (en) | 2006-01-18 | 2008-12-10 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
| JP4753808B2 (ja) * | 2006-06-20 | 2011-08-24 | アサマ化成株式会社 | 感染症予防食品添加用組成物 |
| CA2663377A1 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| US8282928B2 (en) * | 2007-05-30 | 2012-10-09 | The Governors Of The University Of Alberta | Anti-gluten egg yolk antibodies for the treatment of celiac disease |
| ES2599639T3 (es) | 2007-07-09 | 2017-02-02 | Nestec S.A. | Procedimientos para reducir las alergias causadas por alérgenos ambientales |
| KR101661946B1 (ko) | 2007-08-31 | 2016-10-05 | 유니버시티 오브 시카고 | 스타필로코커스 폐 질환 및 상태에 대한 면역화와 관련된 방법 및 조성물 |
| WO2010028072A2 (en) * | 2008-09-02 | 2010-03-11 | Huan Nguyen | Avian antibodies specific to influenza virus and technologically simple methods of their manufacture and use |
| CN102333540B (zh) | 2008-10-06 | 2015-04-22 | 芝加哥大学 | 与细菌eap、emp和/或adsa蛋白相关的组合物和方法 |
| EP2414387B1 (en) | 2009-04-03 | 2015-12-16 | University Of Chicago | Compositions and methods related to protein a (spa) variants |
| EP3461840A1 (en) | 2009-04-27 | 2019-04-03 | Immuron Limited | Anti-lps enriched immunoglobulin preparation for use in treatment and/or prophylaxis of non alcoholic steatohepatitis |
| US10266585B2 (en) | 2009-08-28 | 2019-04-23 | The Board Of Regents Of The Univerity Of Texas System | Methods of treating brain injury |
| JP2013523818A (ja) | 2010-04-05 | 2013-06-17 | ザ・ユニバーシティー・オブ・シカゴ | 免疫反応のエンハンサーとしてのプロテインＡ（ＳｐＡ）抗体に関連する組成物および方法 |
| WO2011140550A2 (en) * | 2010-05-07 | 2011-11-10 | Camas Incorporated | Immunogen adherence and method of making and using same |
| EP2588120B1 (en) | 2010-07-02 | 2017-11-15 | The University of Chicago | Compositions and methods related to protein a (spa) variants |
| CA2808361A1 (en) | 2010-08-17 | 2012-02-23 | Immuron Ltd. | Anti-lps enriched immunoglobulin preparation for use in treatment and/or prophylaxis of inflammatory bowel disease |
| EP2614074A1 (en) | 2010-09-09 | 2013-07-17 | The University of Chicago | Methods and compositions involving protective staphylococcal antigens |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| CN105012950A (zh) * | 2010-11-23 | 2015-11-04 | 潘瑟里克公司 | 用于在广谱、未分化或混合临床应用中治疗的组合物和方法 |
| DE102011006781A1 (de) * | 2011-04-05 | 2012-10-11 | Mat-Malta Advanced Technologies Limited | Antikörperprodukt, umfassend n spezifische Antikörper |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| WO2013025834A2 (en) | 2011-08-15 | 2013-02-21 | The University Of Chicago | Compositions and methods related to antibodies to staphylococcal protein a |
| JP6251730B2 (ja) | 2012-04-26 | 2017-12-20 | ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ | 黄色ブドウ球菌（ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）疾患の間にコアグラーゼ活性を中和する抗体に関連した組成物および方法 |
| US9968668B2 (en) | 2012-04-26 | 2018-05-15 | The University Of Chicago | Staphylococcal coagulase antigens and methods of their use |
| US10125373B2 (en) | 2013-01-22 | 2018-11-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Geminiviral vector for expression of rituximab |
| AU2014253685B2 (en) | 2013-04-19 | 2019-07-11 | Immuron Limited | Methods and compositions for the treatment and/or prophylaxis of clostridium difficile associated disease |
| US10716850B2 (en) | 2014-12-31 | 2020-07-21 | Wellin, Inc. | Anti-inflammatory factor retentate, method of isolation, and use |
| US11246924B2 (en) | 2016-04-01 | 2022-02-15 | Duke University | Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform |
| US10166280B2 (en) | 2016-06-08 | 2019-01-01 | Epitopix, Llc | Polypeptides and immunizing compositions containing Bacillus polypeptides and methods of use |
| WO2019183500A1 (en) | 2018-03-23 | 2019-09-26 | Hung Chiung Yu | Coccidioides antigens and methods of their use |
| US11339387B2 (en) | 2018-05-22 | 2022-05-24 | The Government Of The United States Of America As Represented By The Secretary Of Homeland Security | Modified foot-and-mouth disease virus 3C proteases and methods for processing FMDV P1 precursor polypeptide |
| WO2020176637A1 (en) | 2019-02-26 | 2020-09-03 | Pantheryx, Inc. | Compositions for management of disorders of the gastrointestinal tract |
| US11701423B2 (en) | 2021-03-12 | 2023-07-18 | Lay Sciences, Inc. | Hyperimmunized egg product for treatment or prevention of coronavirus infection |
| WO2022243769A1 (en) | 2021-05-17 | 2022-11-24 | Societe Des Produits Nestle Sa | Cat food supplements comprising an anti-fel-d1 molecule and an animal digest |
| WO2023212604A1 (en) | 2022-04-27 | 2023-11-02 | Lay Sciences, Inc. | Targeted anti-sglt1 avian igy antibodies as treatment of pre-diabetes, type 2 diabetes and gestational diabetes |
| JP2025516644A (ja) | 2022-05-13 | 2025-05-30 | プロディジー バイオテック，インコーポレーテッド | ポリペプチド、抗体及びタンパク質の経口送達のための製剤及びその使用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3128230A (en) * | 1961-04-04 | 1964-04-07 | Sunbury Milk Products Co | Milk having antibodies therein and process for producing same |
| US3376198A (en) * | 1965-07-21 | 1968-04-02 | Collins Products Inc | Method of producing antibodies in milk |
| US3646193A (en) * | 1969-07-25 | 1972-02-29 | Joseph B Michaelson | Iga antibody from lacteal fluids |
| CH590064A5 (forum.php) * | 1973-11-28 | 1977-07-29 | Biokema Sa | |
| US4357272A (en) * | 1978-03-22 | 1982-11-02 | The South African Inventions Development Corporation | Recovering purified antibodies from egg yolk |
| US4585651A (en) * | 1978-10-17 | 1986-04-29 | Stolle Research & Development Corporation | Active/passive immunization of the internal female reproductive organs |
| GB2057451B (en) * | 1979-09-05 | 1983-05-05 | South African Inventions | Immunological preparations comprising egg yolk antibodies |
| US4284623A (en) * | 1979-11-09 | 1981-08-18 | Beck Lee R | Method of treating inflammation using bovine milk |
| NZ201698A (en) * | 1981-08-31 | 1985-12-13 | S L Gaffin | Composition of antibodies specific to endotoxins |
| CA1340372C (en) * | 1984-07-09 | 1999-02-02 | John D. Clements | Production of e. coli lt-b enterotoxin subunit |
-
1984
- 1984-06-19 US US06/622,130 patent/US4748018A/en not_active Expired - Lifetime
-
1985
- 1985-01-25 IL IL74155A patent/IL74155A/xx not_active IP Right Cessation
- 1985-02-04 NZ NZ211030A patent/NZ211030A/en unknown
- 1985-02-05 GR GR850323A patent/GR850323B/el unknown
- 1985-02-06 AT AT90110631T patent/ATE135016T1/de not_active IP Right Cessation
- 1985-02-06 EP EP90110631A patent/EP0395120B1/en not_active Expired - Lifetime
- 1985-02-06 IE IE28985A patent/IE64365B1/en not_active IP Right Cessation
- 1985-02-06 CA CA000473706A patent/CA1275044A/en not_active Expired - Lifetime
- 1985-02-06 EP EP85300786A patent/EP0152270B1/en not_active Expired - Lifetime
- 1985-02-06 DK DK053485A patent/DK166905B1/da not_active IP Right Cessation
- 1985-02-07 JP JP60022742A patent/JP2548115B2/ja not_active Expired - Lifetime
- 1985-02-07 DE DE3504221A patent/DE3504221C2/de not_active Expired - Lifetime
-
1988
- 1988-10-26 CA CA000581407A patent/CA1276884C/en not_active Expired - Lifetime
- 1988-10-26 CA CA000581406A patent/CA1276883C/en not_active Expired - Lifetime
-
1990
- 1990-09-20 DK DK227190A patent/DK227190D0/da not_active Application Discontinuation
-
1991
- 1991-06-14 JP JP3169314A patent/JP2543633B2/ja not_active Expired - Lifetime
-
1995
- 1995-12-13 JP JP7324840A patent/JP2690476B2/ja not_active Expired - Lifetime
- 1995-12-13 JP JP7324830A patent/JP2723870B2/ja not_active Expired - Lifetime
- 1995-12-27 JP JP7341970A patent/JP2698778B2/ja not_active Expired - Lifetime
- 1995-12-27 JP JP7341971A patent/JP2698779B2/ja not_active Expired - Lifetime
-
1997
- 1997-09-02 HK HK97101706A patent/HK1000183A1/en not_active IP Right Cessation
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