NZ184610A - 5-benzoyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acids and pharmaceutical compositions - Google Patents

5-benzoyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acids and pharmaceutical compositions

Info

Publication number
NZ184610A
NZ184610A NZ184610A NZ18461077A NZ184610A NZ 184610 A NZ184610 A NZ 184610A NZ 184610 A NZ184610 A NZ 184610A NZ 18461077 A NZ18461077 A NZ 18461077A NZ 184610 A NZ184610 A NZ 184610A
Authority
NZ
New Zealand
Prior art keywords
pyrrolo
pyrrole
dihydro
benzoyl
pharmaceutical compositions
Prior art date
Application number
NZ184610A
Other languages
English (en)
Inventor
Jm Muchowski
Af Kluge
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107410&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ184610(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US05/771,286 external-priority patent/US4089969A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NZ184610A publication Critical patent/NZ184610A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
NZ184610A 1976-07-14 1977-07-11 5-benzoyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acids and pharmaceutical compositions NZ184610A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70490976A 1976-07-14 1976-07-14
US05/771,286 US4089969A (en) 1976-07-14 1977-02-23 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof

Publications (1)

Publication Number Publication Date
NZ184610A true NZ184610A (en) 1979-03-28

Family

ID=27107410

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ184610A NZ184610A (en) 1976-07-14 1977-07-11 5-benzoyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acids and pharmaceutical compositions

Country Status (27)

Country Link
JP (1) JPS539788A (enrdf_load_stackoverflow)
AR (1) AR224997A1 (enrdf_load_stackoverflow)
CA (1) CA1102809A (enrdf_load_stackoverflow)
CH (3) CH641458A5 (enrdf_load_stackoverflow)
CS (1) CS204954B2 (enrdf_load_stackoverflow)
DE (2) DE2731678A1 (enrdf_load_stackoverflow)
DK (1) DK151886C (enrdf_load_stackoverflow)
ES (2) ES460706A1 (enrdf_load_stackoverflow)
FI (1) FI63406C (enrdf_load_stackoverflow)
FR (2) FR2358406A1 (enrdf_load_stackoverflow)
GB (1) GB1554075A (enrdf_load_stackoverflow)
GR (1) GR61111B (enrdf_load_stackoverflow)
HK (1) HK15981A (enrdf_load_stackoverflow)
HU (1) HU174224B (enrdf_load_stackoverflow)
IE (1) IE45253B1 (enrdf_load_stackoverflow)
IL (2) IL52493A (enrdf_load_stackoverflow)
IT (1) IT1117313B (enrdf_load_stackoverflow)
MX (1) MX163202B (enrdf_load_stackoverflow)
MY (1) MY8100357A (enrdf_load_stackoverflow)
NL (2) NL186318C (enrdf_load_stackoverflow)
NO (1) NO147564C (enrdf_load_stackoverflow)
NZ (1) NZ184610A (enrdf_load_stackoverflow)
PL (4) PL124711B1 (enrdf_load_stackoverflow)
PT (1) PT66780B (enrdf_load_stackoverflow)
SE (1) SE434643B (enrdf_load_stackoverflow)
SU (1) SU695558A3 (enrdf_load_stackoverflow)
YU (1) YU40816B (enrdf_load_stackoverflow)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140698A (en) * 1977-07-25 1979-02-20 Syntex (Usa) Inc. 1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
JPS55124633A (en) * 1979-03-19 1980-09-25 Sohachi Takeuchi Manufacturing method of tubular vessel
US4344943A (en) * 1980-06-09 1982-08-17 Syntex (U.S.A.) Inc. 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
US4511724A (en) * 1982-06-10 1985-04-16 Merck & Co., Inc. 5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
JPS5910589A (ja) * 1982-06-10 1984-01-20 メルク　エンド　カムパニー　インコーポレーテツド 抗炎症剤および鎮痛剤として新規な５−（ピロ−ル−２−オイル）−１，２−ジヒドロ−３Ｈ−ピロロ〔１，２−ａ〕ピロ−ル誘導体
US4874871A (en) * 1987-03-25 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds
JPH0739418B2 (ja) * 1987-09-10 1995-05-01 久光製薬株式会社 新規な３−アロイル−６，７−ジヒドロ−５Ｈ−ピロロ〔１，２−ｃ〕イミダゾール−７−カルボン酸誘導体
JP2649168B2 (ja) * 1988-02-25 1997-09-03 久光製薬株式会社 新規な５，６−ジフェニル−１，２−ジヒドロ−３Ｈ−ピロロ［１，２−ａ］ピロール−１−カルボン酸誘導体
IT1250691B (it) * 1991-07-22 1995-04-21 Giancarlo Santus Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.
DE69229506T2 (de) * 1991-11-11 1999-10-28 Hisamitsu Pharmaceutical Co., Inc. Ketorolac enthaltender warmer umschlag
DE4300697C1 (de) * 1993-01-13 1994-05-19 Roemmers Sa Keterolac-Derivat mit wesentlich geringerer gastrointestinaler Reizung und Ulzeration
US5622948A (en) * 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents
JP2008210666A (ja) * 2007-02-27 2008-09-11 Okamura Corp 商品陳列棚における照明装置
CA3202461A1 (en) * 2020-12-16 2022-06-23 Robert T. Streeper Dicarboxylic acid esters for inducing an analgesic effect

Also Published As

Publication number Publication date
ES460706A1 (es) 1978-12-01
IL52493A0 (en) 1977-10-31
FR2358406B1 (enrdf_load_stackoverflow) 1981-04-17
NL7707651A (nl) 1978-01-17
PL124711B1 (en) 1983-02-28
DK151886C (da) 1988-06-06
AU513384B2 (en) 1980-11-27
HK15981A (en) 1981-05-01
FR2375234A1 (fr) 1978-07-21
NL186318B (nl) 1990-06-01
DE2760330C2 (enrdf_load_stackoverflow) 1989-06-15
CH646972A5 (en) 1984-12-28
DK151886B (da) 1988-01-11
CH646973A5 (en) 1984-12-28
NL930021I2 (nl) 1997-03-03
GB1554075A (en) 1979-10-17
DE2731678A1 (de) 1978-03-16
IE45253L (en) 1978-01-14
SU695558A3 (ru) 1979-10-30
NL186318C (nl) 1990-11-01
SE7708141L (sv) 1978-01-15
FR2358406A1 (fr) 1978-02-10
NO147564B (no) 1983-01-24
PT66780A (fr) 1977-08-01
CH641458A5 (en) 1984-02-29
DK307577A (da) 1978-01-15
CA1102809A (en) 1981-06-09
IT1117313B (it) 1986-02-17
DE2731678C2 (enrdf_load_stackoverflow) 1989-06-08
YU172177A (en) 1983-09-30
JPS6254109B2 (enrdf_load_stackoverflow) 1987-11-13
PT66780B (fr) 1978-12-18
PL199603A1 (pl) 1978-04-24
JPS539788A (en) 1978-01-28
GR61111B (en) 1978-09-12
ES470214A1 (es) 1979-09-16
MY8100357A (en) 1981-12-31
IL52493A (en) 1982-02-28
FR2375234B1 (enrdf_load_stackoverflow) 1980-11-07
AU2697577A (en) 1979-01-18
CS204954B2 (en) 1981-04-30
YU40816B (en) 1986-06-30
AR224997A1 (es) 1982-02-15
IL58779A0 (en) 1980-02-29
NO772494L (no) 1978-01-17
NL930021I1 (nl) 1993-05-03
PL109390B1 (en) 1980-05-31
PL124444B1 (en) 1983-01-31
PL124445B1 (en) 1983-01-31
SE434643B (sv) 1984-08-06
FI63406B (fi) 1983-02-28
HU174224B (hu) 1979-11-28
NO147564C (no) 1983-05-18
IE45253B1 (en) 1982-07-14
FI772153A7 (enrdf_load_stackoverflow) 1978-01-15
MX163202B (es) 1992-02-20
FI63406C (fi) 1983-06-10

Similar Documents

Publication Publication Date Title
ZA774238B (en) 5-aroyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof
AU518169B2 (en) 5-(2-PYRROLO-l, 2-DIHYDRO-3H-PYRROLO f 1 2-a 1 PYRROLE-1 CARBOXYLIC ACID DERIVATIVES
DE3065270D1 (en) Substituted pyrazolo (1,5-a) pyrimidines, and their preparation
PH12259A (en) Substituted imidazo(1,2-a)pyridines and composition containing them
NZ184610A (en) 5-benzoyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acids and pharmaceutical compositions
IL55181A (en) Preparation of 5-substituted-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acids and the corresponding novel nitrile starting materials
PH16228A (en) Triazolo pyridazine derivatives,pharmaceutical composition containing the same and their use
IL50930A (en) 1-alkyl-4-oxo-1,6,7,8-tetrahydro-4h-pyrido(1,2-a)pyrimidine-3-carboxamide derivatives,their preparation and pharmaceutical compositions containing them
DE3377713D1 (en) New 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole derivatives as anti-inflammatory and analgesic agents
AU3233178A (en) 4-subituted imidazo(1, 2-a) quinoxaline
NZ184611A (en) 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acids and phsrmaceutical compositions
CS528780A2 (en) Zpusob vyroby substituovanych pyrido-(1,2-a)pyrimidinu
IL61535A (en) 5-oxo-5h-thiazolo(3,2-a)pyrimidine-6-carboxylic acids and n-(5-tetrazolyl)-carboxamide derivatives thereof
IL59987A0 (en) 3-substituted-tetrahydro-pyrrolo(1,2-a)pyrimidines,process for the preparation thereof and pharmaceutical compositions containing them
FI781797A7 (fi) Foerfarande foer framstaellning av imidazo (1,2-a) pyridiner
AU514427B2 (en) Pyrimido (1, 2-a)denzimidazole derivatives
IL56132A (en) 9-amino-4h-pyrido(1,2-a)pyrimidin-4-one compounds,their preparation and pharmaceutical compositions containing them
GB1551166A (en) Pyrazolo (1,5-a)quinoxaline-3-carboxylic acid and derivatives thereof
IL49161A (en) Imidazo(1,5-a)(1,4)-diazepine derivatives,their manufacture and pharmaceutical compositions containing them
CS340780A2 (en) Zpusob vyroby pyrazolo (1,5 c) chinazolinovych derivatu
IL60026A0 (en) 3-substituted-hexahydro-pyrimido(1,2-a azepins,process for the preparation thereof and pharmaceutical compositions containing the same
HRP940490B1 (en) 5-AROYL-1,2-DIHYDRO-3H-PYRROLO(1,2-a)PYRROLE-1-CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THE PRODUCTION THEREOF
IL60027A0 (en) 9-hydrazono-6,7,8,9-tetrahydro-4h-pyrido(1,2-a)pyrimidin-4-one derivatives and process for their preparation
IL58779A (en) Alkyl 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylates and their preparation
AU513384C (en) 5-aroyl-l., 2-dihydro-3H-pyrrolo(1, 2-a) pyrrole 1-carboxylic acid derivatives