DK307577A - 5-aroyl-1,2-dihydro-3h-pyrrol (1,2-a) pyrrol-1-carboxylsyrederivater og fremgangsmade til fremstilling deraf - Google Patents

5-aroyl-1,2-dihydro-3h-pyrrol (1,2-a) pyrrol-1-carboxylsyrederivater og fremgangsmade til fremstilling deraf

Info

Publication number
DK307577A
DK307577A DK307577A DK307577A DK307577A DK 307577 A DK307577 A DK 307577A DK 307577 A DK307577 A DK 307577A DK 307577 A DK307577 A DK 307577A DK 307577 A DK307577 A DK 307577A
Authority
DK
Denmark
Prior art keywords
pyrrol
aroyl
dihydro
carboxylic acid
acid derivatives
Prior art date
Application number
DK307577A
Other languages
English (en)
Other versions
DK151886C (da
DK151886B (da
Inventor
J M Muchowski
A F Kluge
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107410&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK307577(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US05/771,286 external-priority patent/US4089969A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK307577A publication Critical patent/DK307577A/da
Priority to DK479880A priority Critical patent/DK151335C/da
Priority to DK479780A priority patent/DK152733C/da
Priority to DK480080A priority patent/DK151337C/da
Priority to DK479980A priority patent/DK151336C/da
Publication of DK151886B publication Critical patent/DK151886B/da
Application granted granted Critical
Publication of DK151886C publication Critical patent/DK151886C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
DK307577A 1976-07-14 1977-07-07 Analogifremgangsmaade til fremstilling af (dl) eller (1) 5-benzoyl-1,2-dihydro-3h-pyrrolooe1,2-aaapyrrol-1-carboxylsyreestere DK151886C (da)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DK479880A DK151335C (da) 1976-07-14 1980-11-11 Analogifremgangsmaade til fremstilling af (dl)- eller (l)-5-benzoyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyreestere eller salte
DK479780A DK152733C (da) 1976-07-14 1980-11-11 (d)-5-benzoyl-1,2-dihydro-3h-pyrrolooe1,2-aaa-pyrrol-1-carboxylsyrer eller estere eller salte deraf til anvendelse som mellemprodukter ved fremstilling af tilsvarende (dl)- eller (1)-carboxylsyrederivater
DK480080A DK151337C (da) 1976-07-14 1980-11-11 Analogifremgangsmaade til fremstilling af (dl)- eller (l)-5-benzoyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrederivater
DK479980A DK151336C (da) 1976-07-14 1980-11-11 Analogifremgangsmaade til fremstilling af en (dl)- eller (l)-5-benzoyl-1,2-dihydro-3h-pyrrol(1,2-a)pyrrol-1-carboxylsyre

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70490976A 1976-07-14 1976-07-14
US70490976 1976-07-14
US05/771,286 US4089969A (en) 1976-07-14 1977-02-23 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
US77128677 1977-02-23

Publications (3)

Publication Number Publication Date
DK307577A true DK307577A (da) 1978-01-15
DK151886B DK151886B (da) 1988-01-11
DK151886C DK151886C (da) 1988-06-06

Family

ID=27107410

Family Applications (1)

Application Number Title Priority Date Filing Date
DK307577A DK151886C (da) 1976-07-14 1977-07-07 Analogifremgangsmaade til fremstilling af (dl) eller (1) 5-benzoyl-1,2-dihydro-3h-pyrrolooe1,2-aaapyrrol-1-carboxylsyreestere

Country Status (27)

Country Link
JP (1) JPS539788A (da)
AR (1) AR224997A1 (da)
CA (1) CA1102809A (da)
CH (3) CH641458A5 (da)
CS (1) CS204954B2 (da)
DE (2) DE2760330C2 (da)
DK (1) DK151886C (da)
ES (2) ES460706A1 (da)
FI (1) FI63406C (da)
FR (2) FR2358406A1 (da)
GB (1) GB1554075A (da)
GR (1) GR61111B (da)
HK (1) HK15981A (da)
HU (1) HU174224B (da)
IE (1) IE45253B1 (da)
IL (2) IL52493A (da)
IT (1) IT1117313B (da)
MX (1) MX163202B (da)
MY (1) MY8100357A (da)
NL (2) NL186318C (da)
NO (1) NO147564C (da)
NZ (1) NZ184610A (da)
PL (4) PL124445B1 (da)
PT (1) PT66780B (da)
SE (1) SE434643B (da)
SU (1) SU695558A3 (da)
YU (1) YU40816B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140698A (en) * 1977-07-25 1979-02-20 Syntex (Usa) Inc. 1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
JPS55124633A (en) * 1979-03-19 1980-09-25 Sohachi Takeuchi Manufacturing method of tubular vessel
US4344943A (en) * 1980-06-09 1982-08-17 Syntex (U.S.A.) Inc. 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
JPS5910589A (ja) * 1982-06-10 1984-01-20 メルク　エンド　カムパニー　インコーポレーテツド 抗炎症剤および鎮痛剤として新規な５−（ピロ−ル−２−オイル）−１，２−ジヒドロ−３Ｈ−ピロロ〔１，２−ａ〕ピロ−ル誘導体
US4511724A (en) * 1982-06-10 1985-04-16 Merck & Co., Inc. 5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
US4874871A (en) * 1987-03-25 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds
JPH0739418B2 (ja) * 1987-09-10 1995-05-01 久光製薬株式会社 新規な３−アロイル−６，７−ジヒドロ−５Ｈ−ピロロ〔１，２−ｃ〕イミダゾール−７−カルボン酸誘導体
JP2649168B2 (ja) * 1988-02-25 1997-09-03 久光製薬株式会社 新規な５，６−ジフェニル−１，２−ジヒドロ−３Ｈ−ピロロ［１，２−ａ］ピロール−１−カルボン酸誘導体
IT1250691B (it) * 1991-07-22 1995-04-21 Giancarlo Santus Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.
ES2136093T3 (es) * 1991-11-11 1999-11-16 Hisamitsu Pharmaceutical Co Fomentacion que contiene cetorolac.
DE4300697C1 (de) * 1993-01-13 1994-05-19 Roemmers Sa Keterolac-Derivat mit wesentlich geringerer gastrointestinaler Reizung und Ulzeration
US5622948A (en) * 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents
JP2008210666A (ja) * 2007-02-27 2008-09-11 Okamura Corp 商品陳列棚における照明装置

Also Published As

Publication number Publication date
NO147564C (no) 1983-05-18
CA1102809A (en) 1981-06-09
SE7708141L (sv) 1978-01-15
DK151886C (da) 1988-06-06
PL199603A1 (pl) 1978-04-24
HU174224B (hu) 1979-11-28
CH641458A5 (en) 1984-02-29
NL930021I1 (nl) 1993-05-03
NL930021I2 (nl) 1997-03-03
IE45253L (en) 1978-01-14
FI772153A (da) 1978-01-15
GB1554075A (en) 1979-10-17
IL58779A0 (en) 1980-02-29
AU2697577A (en) 1979-01-18
FR2375234B1 (da) 1980-11-07
DK151886B (da) 1988-01-11
IE45253B1 (en) 1982-07-14
FI63406B (fi) 1983-02-28
IL52493A0 (en) 1977-10-31
NZ184610A (en) 1979-03-28
CH646973A5 (en) 1984-12-28
CH646972A5 (en) 1984-12-28
NL186318B (nl) 1990-06-01
PT66780A (fr) 1977-08-01
PT66780B (fr) 1978-12-18
FR2375234A1 (fr) 1978-07-21
DE2731678A1 (de) 1978-03-16
HK15981A (en) 1981-05-01
IT1117313B (it) 1986-02-17
DE2760330C2 (da) 1989-06-15
DE2731678C2 (da) 1989-06-08
JPS6254109B2 (da) 1987-11-13
MX163202B (es) 1992-02-20
AU513384B2 (en) 1980-11-27
JPS539788A (en) 1978-01-28
CS204954B2 (en) 1981-04-30
MY8100357A (en) 1981-12-31
YU40816B (en) 1986-06-30
FR2358406A1 (fr) 1978-02-10
FR2358406B1 (da) 1981-04-17
IL52493A (en) 1982-02-28
AR224997A1 (es) 1982-02-15
NL7707651A (nl) 1978-01-17
ES460706A1 (es) 1978-12-01
PL124445B1 (en) 1983-01-31
NO772494L (no) 1978-01-17
NO147564B (no) 1983-01-24
PL109390B1 (en) 1980-05-31
PL124444B1 (en) 1983-01-31
NL186318C (nl) 1990-11-01
FI63406C (fi) 1983-06-10
SU695558A3 (ru) 1979-10-30
GR61111B (en) 1978-09-12
ES470214A1 (es) 1979-09-16
YU172177A (en) 1983-09-30
PL124711B1 (en) 1983-02-28
SE434643B (sv) 1984-08-06

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