NO982249D0 - Blodplate-aggregasjonsinhibitorer - Google Patents

Blodplate-aggregasjonsinhibitorer

Info

Publication number
NO982249D0
NO982249D0 NO982249A NO982249A NO982249D0 NO 982249 D0 NO982249 D0 NO 982249D0 NO 982249 A NO982249 A NO 982249A NO 982249 A NO982249 A NO 982249A NO 982249 D0 NO982249 D0 NO 982249D0
Authority
NO
Norway
Prior art keywords
alkyl
pais
independently
assay
benzyl
Prior art date
Application number
NO982249A
Other languages
English (en)
Other versions
NO982249L (no
NO312965B1 (no
Inventor
Robert Scarborough
David Lawrence Wolf
Israel F Charo
Original Assignee
Cor Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27408820&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO982249(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of NO982249L publication Critical patent/NO982249L/no
Application filed by Cor Therapeutics Inc filed Critical Cor Therapeutics Inc
Publication of NO982249D0 publication Critical patent/NO982249D0/no
Publication of NO312965B1 publication Critical patent/NO312965B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
NO19982249A 1989-06-16 1998-05-15 Blodplate-aggregasjonsinhibitorer NO312965B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36750989A 1989-06-16 1989-06-16
US41802889A 1989-10-06 1989-10-06
US07/483,229 US5318899A (en) 1989-06-16 1990-02-20 Platelet aggregation inhibitors
PCT/US1990/003417 WO1990015620A1 (en) 1989-06-16 1990-06-15 Platelet aggregation inhibitors

Publications (3)

Publication Number Publication Date
NO982249L NO982249L (no) 1992-01-31
NO982249D0 true NO982249D0 (no) 1998-05-15
NO312965B1 NO312965B1 (no) 2002-07-22

Family

ID=27408820

Family Applications (3)

Application Number Title Priority Date Filing Date
NO914962A NO304267B1 (no) 1989-06-16 1991-12-16 AnalogifremgangsmÕte for fremstilling av en terapeutisk aktiv spesifikk blodplateaggregasjonsinhibitor (PAI) peptid
NO19982249A NO312965B1 (no) 1989-06-16 1998-05-15 Blodplate-aggregasjonsinhibitorer
NO2000008C NO2000008I2 (no) 1989-06-16 2000-09-06 Analogifremgangsmaate for fremstilling av en terapeutisk aktiv spesifikk blodplateaggregasjonsinhibitor

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO914962A NO304267B1 (no) 1989-06-16 1991-12-16 AnalogifremgangsmÕte for fremstilling av en terapeutisk aktiv spesifikk blodplateaggregasjonsinhibitor (PAI) peptid

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2000008C NO2000008I2 (no) 1989-06-16 2000-09-06 Analogifremgangsmaate for fremstilling av en terapeutisk aktiv spesifikk blodplateaggregasjonsinhibitor

Country Status (16)

Country Link
US (4) US5318899A (no)
EP (2) EP0477295B2 (no)
JP (1) JP3281370B2 (no)
KR (1) KR0180918B1 (no)
AT (1) ATE146969T1 (no)
CA (2) CA2059124C (no)
DE (2) DE19975072I2 (no)
DK (1) DK0477295T4 (no)
ES (1) ES2097150T5 (no)
FI (1) FI104364B (no)
HU (1) HU216318B (no)
LU (1) LU90488I2 (no)
NL (1) NL990043I2 (no)
NO (3) NO304267B1 (no)
RU (1) RU2156468C2 (no)
WO (1) WO1990015620A1 (no)

Families Citing this family (67)

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US5827821A (en) * 1987-12-10 1998-10-27 The Burnham Institute Conformationally stabilized cell adhesion peptides
EP0394326B1 (en) * 1987-12-10 1996-07-31 La Jolla Cancer Research Foundation Methods for the production of conformationally stabilized cell adhesion peptides
US5770198A (en) * 1988-05-18 1998-06-23 The Research Foundation Of The State Of New York Platelet-specific chimeric 7E3 immunoglobulin
US5807828A (en) * 1989-06-16 1998-09-15 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5318899A (en) * 1989-06-16 1994-06-07 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5643872A (en) * 1989-10-23 1997-07-01 Smithkline Beecham Corporation Cyclic anti-aggregatory peptides
AU6470590A (en) 1989-10-23 1991-04-26 Smithkline Beecham Corporation Cyclic anti-aggregatory peptides
US5612311A (en) 1990-04-06 1997-03-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5780303A (en) * 1990-04-06 1998-07-14 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5648330A (en) * 1990-04-06 1997-07-15 La Jolla Cancer Research Foundation Method and composition for treating vascular graft occlusion
US6521594B1 (en) 1990-04-06 2003-02-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
DK0527798T3 (da) * 1990-04-06 1997-12-15 Jolla Cancer Res Found Fremgangsmåde og sammensætning til behandling af thrombose
US5192746A (en) * 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
CA2092315A1 (en) * 1990-11-02 1992-05-03 John P. Burnier Platelet aggregation inhibitors
US5342830A (en) * 1990-11-16 1994-08-30 Cor Therapeutics, Inc. Antithrombosis agents
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
WO1992017492A1 (en) * 1991-04-05 1992-10-15 Genentech, Inc. PLATELET AGGREGATION INHIBITORS HAVING HIGH SPECIFICITY FOR GP IIbIII¿a?
US5250679A (en) * 1991-10-18 1993-10-05 Genentech, Inc. Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
US5663166A (en) * 1991-10-18 1997-09-02 Genentech, Inc. Nonpeptidyl integrin inhibitors having specificity for the GPIIb IIIa receptor
US5227490A (en) * 1992-02-21 1993-07-13 Merck & Co., Inc. Fibrinogen receptor antagonists
DE4212304A1 (de) * 1992-04-13 1993-10-14 Cassella Ag Asparaginsäurederivate, ihre Herstellung und Verwendung
US5747447A (en) * 1992-04-30 1998-05-05 Cor Therapeutics Stable polypeptide composition
WO1993024520A1 (en) * 1992-06-04 1993-12-09 Merrell Dow Pharmaceuticals Inc. Conformationally restrained peptide analogs as antiplatelet agents
IL106197A (en) * 1992-07-30 1999-11-30 Cor Therapeutics Inc Agagonists for the rhombin receptors and pharmaceutical preparations containing them
ZW4194A1 (en) * 1993-03-29 1994-12-21 Zeneca Ltd Heterocyclic compounds
US5750754A (en) * 1993-03-29 1998-05-12 Zeneca Limited Heterocyclic compounds
DE69411900T2 (de) * 1993-03-29 1998-12-10 Zeneca Ltd., London Heterozyklische derivate als plätchenaggregationsinhibitoren
US5753659A (en) * 1993-03-29 1998-05-19 Zeneca Limited Heterocyclic compouds
US5652242A (en) * 1993-03-29 1997-07-29 Zeneca Limited Heterocyclic derivatives
JPH09501910A (ja) * 1993-06-18 1997-02-25 ラ ホヤ キャンサー リサーチ ファウンデイション 血栓症処置のための方法および組成物
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US5877224A (en) * 1995-07-28 1999-03-02 Rutgers, The State University Of New Jersey Polymeric drug formulations
WO1997025999A1 (en) * 1996-01-16 1997-07-24 Rensselaer Polytechnic Institute Peptides for altering osteoblast adhesion
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US6818617B1 (en) 1997-08-15 2004-11-16 Temple University- Of The Commonwealth System Of Higher Education EC-3, an inhibitor of α4β1 and α4β7 integrins
US6210904B1 (en) 1997-10-14 2001-04-03 Merck & Co., Inc. Anticoagulant test
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US6087332A (en) * 1997-12-23 2000-07-11 Galler; Lawrence Isaac Streptokinase derivatives with high affinity for activated platelets and methods of their production and use in thrombolytic therapy
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US7691968B2 (en) * 2002-05-03 2010-04-06 Avecia Biologics Limited Process for the synthesis of peptides amides by side-chain attachment to a solid phase
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WO2008020743A2 (fr) * 2006-08-16 2008-02-21 Wisdom Asset Company Procédé permettant d'extraire un inhibiteur de l'agrégation plaquettaire du venin d'agkistrodon blomhoffii ussuriensis
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GB2462022B (en) 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods thereof
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RU2444731C1 (ru) * 2010-10-06 2012-03-10 Российская Федерация, от имени которой выступает Министерство образования и науки Российской Федерации (Минобрнауки России) Способ выравнивания хроматограмм пептидных смесей
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Also Published As

Publication number Publication date
ATE146969T1 (de) 1997-01-15
DE69029579D1 (de) 1997-02-13
DK0477295T3 (da) 1997-07-07
NO982249L (no) 1992-01-31
NO312965B1 (no) 2002-07-22
WO1990015620A1 (en) 1990-12-27
ES2097150T3 (es) 1997-04-01
NO304267B1 (no) 1998-11-23
AU636159B2 (en) 1993-04-22
EP0477295B1 (en) 1997-01-02
NO914962L (no) 1992-01-31
LU90488I2 (fr) 2000-02-15
CA2059124C (en) 2002-08-20
FI104364B (fi) 2000-01-14
DE69029579T3 (de) 2006-06-22
EP0477295A1 (en) 1992-04-01
NL990043I1 (nl) 2000-02-01
AU6036990A (en) 1991-01-08
DE69029579T2 (de) 1997-07-24
US5318899A (en) 1994-06-07
US5958732A (en) 1999-09-28
HU216318B (hu) 1999-06-28
US5496724A (en) 1996-03-05
DK0477295T4 (da) 2005-12-12
KR0180918B1 (ko) 1999-04-01
CA2388770A1 (en) 1990-12-27
NL990043I2 (nl) 2000-04-03
HU905490D0 (en) 1992-03-30
RU2156468C2 (ru) 2000-09-20
HUT59835A (en) 1992-07-28
KR920702627A (ko) 1992-10-06
DE19975072I2 (de) 2011-01-20
JP3281370B2 (ja) 2002-05-13
NO914962D0 (no) 1991-12-16
CA2059124A1 (en) 1990-12-17
NO2000008I2 (no) 2006-01-16
EP0477295A4 (en) 1992-10-07
FI915919A0 (fi) 1991-12-16
EP0751219A1 (en) 1997-01-02
EP0477295B2 (en) 2005-11-16
DE19975072I1 (de) 2000-03-09
JPH05500750A (ja) 1993-02-18
ES2097150T5 (es) 2006-06-16
US5736339A (en) 1998-04-07

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