NO914962L - Blodplate-aggregasjonsinhibitorer - Google Patents

Blodplate-aggregasjonsinhibitorer

Info

Publication number
NO914962L
NO914962L NO91914962A NO914962A NO914962L NO 914962 L NO914962 L NO 914962L NO 91914962 A NO91914962 A NO 91914962A NO 914962 A NO914962 A NO 914962A NO 914962 L NO914962 L NO 914962L
Authority
NO
Norway
Prior art keywords
alkyl
pais
independently
assay
benzyl
Prior art date
Application number
NO91914962A
Other languages
English (en)
Other versions
NO304267B1 (no
NO914962D0 (no
Inventor
Robert M Scarborough
David Lawrence Wolf
Israel F Charo
Original Assignee
Cor Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27408820&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO914962(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cor Therapeutics Inc filed Critical Cor Therapeutics Inc
Publication of NO914962D0 publication Critical patent/NO914962D0/no
Publication of NO914962L publication Critical patent/NO914962L/no
Publication of NO304267B1 publication Critical patent/NO304267B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
NO914962A 1989-06-16 1991-12-16 AnalogifremgangsmÕte for fremstilling av en terapeutisk aktiv spesifikk blodplateaggregasjonsinhibitor (PAI) peptid NO304267B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36750989A 1989-06-16 1989-06-16
US41802889A 1989-10-06 1989-10-06
US07/483,229 US5318899A (en) 1989-06-16 1990-02-20 Platelet aggregation inhibitors
PCT/US1990/003417 WO1990015620A1 (en) 1989-06-16 1990-06-15 Platelet aggregation inhibitors

Publications (3)

Publication Number Publication Date
NO914962D0 NO914962D0 (no) 1991-12-16
NO914962L true NO914962L (no) 1992-01-31
NO304267B1 NO304267B1 (no) 1998-11-23

Family

ID=27408820

Family Applications (3)

Application Number Title Priority Date Filing Date
NO914962A NO304267B1 (no) 1989-06-16 1991-12-16 AnalogifremgangsmÕte for fremstilling av en terapeutisk aktiv spesifikk blodplateaggregasjonsinhibitor (PAI) peptid
NO19982249A NO312965B1 (no) 1989-06-16 1998-05-15 Blodplate-aggregasjonsinhibitorer
NO2000008C NO2000008I2 (no) 1989-06-16 2000-09-06 Analogifremgangsmaate for fremstilling av en terapeutisk aktiv spesifikk blodplateaggregasjonsinhibitor

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO19982249A NO312965B1 (no) 1989-06-16 1998-05-15 Blodplate-aggregasjonsinhibitorer
NO2000008C NO2000008I2 (no) 1989-06-16 2000-09-06 Analogifremgangsmaate for fremstilling av en terapeutisk aktiv spesifikk blodplateaggregasjonsinhibitor

Country Status (16)

Country Link
US (4) US5318899A (no)
EP (2) EP0477295B2 (no)
JP (1) JP3281370B2 (no)
KR (1) KR0180918B1 (no)
AT (1) ATE146969T1 (no)
CA (2) CA2059124C (no)
DE (2) DE19975072I2 (no)
DK (1) DK0477295T4 (no)
ES (1) ES2097150T5 (no)
FI (1) FI104364B (no)
HU (1) HU216318B (no)
LU (1) LU90488I2 (no)
NL (1) NL990043I2 (no)
NO (3) NO304267B1 (no)
RU (1) RU2156468C2 (no)
WO (1) WO1990015620A1 (no)

Families Citing this family (67)

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US5827821A (en) * 1987-12-10 1998-10-27 The Burnham Institute Conformationally stabilized cell adhesion peptides
EP0394326B1 (en) * 1987-12-10 1996-07-31 La Jolla Cancer Research Foundation Methods for the production of conformationally stabilized cell adhesion peptides
US5770198A (en) * 1988-05-18 1998-06-23 The Research Foundation Of The State Of New York Platelet-specific chimeric 7E3 immunoglobulin
US5807828A (en) * 1989-06-16 1998-09-15 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5318899A (en) * 1989-06-16 1994-06-07 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5643872A (en) * 1989-10-23 1997-07-01 Smithkline Beecham Corporation Cyclic anti-aggregatory peptides
AU6470590A (en) 1989-10-23 1991-04-26 Smithkline Beecham Corporation Cyclic anti-aggregatory peptides
US5612311A (en) 1990-04-06 1997-03-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5780303A (en) * 1990-04-06 1998-07-14 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5648330A (en) * 1990-04-06 1997-07-15 La Jolla Cancer Research Foundation Method and composition for treating vascular graft occlusion
US6521594B1 (en) 1990-04-06 2003-02-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
DK0527798T3 (da) * 1990-04-06 1997-12-15 Jolla Cancer Res Found Fremgangsmåde og sammensætning til behandling af thrombose
US5192746A (en) * 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
CA2092315A1 (en) * 1990-11-02 1992-05-03 John P. Burnier Platelet aggregation inhibitors
US5342830A (en) * 1990-11-16 1994-08-30 Cor Therapeutics, Inc. Antithrombosis agents
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
WO1992017492A1 (en) * 1991-04-05 1992-10-15 Genentech, Inc. PLATELET AGGREGATION INHIBITORS HAVING HIGH SPECIFICITY FOR GP IIbIII¿a?
US5250679A (en) * 1991-10-18 1993-10-05 Genentech, Inc. Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
US5663166A (en) * 1991-10-18 1997-09-02 Genentech, Inc. Nonpeptidyl integrin inhibitors having specificity for the GPIIb IIIa receptor
US5227490A (en) * 1992-02-21 1993-07-13 Merck & Co., Inc. Fibrinogen receptor antagonists
DE4212304A1 (de) * 1992-04-13 1993-10-14 Cassella Ag Asparaginsäurederivate, ihre Herstellung und Verwendung
US5747447A (en) * 1992-04-30 1998-05-05 Cor Therapeutics Stable polypeptide composition
WO1993024520A1 (en) * 1992-06-04 1993-12-09 Merrell Dow Pharmaceuticals Inc. Conformationally restrained peptide analogs as antiplatelet agents
IL106197A (en) * 1992-07-30 1999-11-30 Cor Therapeutics Inc Agagonists for the rhombin receptors and pharmaceutical preparations containing them
ZW4194A1 (en) * 1993-03-29 1994-12-21 Zeneca Ltd Heterocyclic compounds
US5750754A (en) * 1993-03-29 1998-05-12 Zeneca Limited Heterocyclic compounds
DE69411900T2 (de) * 1993-03-29 1998-12-10 Zeneca Ltd., London Heterozyklische derivate als plätchenaggregationsinhibitoren
US5753659A (en) * 1993-03-29 1998-05-19 Zeneca Limited Heterocyclic compouds
US5652242A (en) * 1993-03-29 1997-07-29 Zeneca Limited Heterocyclic derivatives
JPH09501910A (ja) * 1993-06-18 1997-02-25 ラ ホヤ キャンサー リサーチ ファウンデイション 血栓症処置のための方法および組成物
US5770575A (en) * 1994-03-16 1998-06-23 Ortho Pharmaceutical Corporation Nipecotic acid derivatives as antithrombotic compounds
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US5877224A (en) * 1995-07-28 1999-03-02 Rutgers, The State University Of New Jersey Polymeric drug formulations
WO1997025999A1 (en) * 1996-01-16 1997-07-24 Rensselaer Polytechnic Institute Peptides for altering osteoblast adhesion
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US6818617B1 (en) 1997-08-15 2004-11-16 Temple University- Of The Commonwealth System Of Higher Education EC-3, an inhibitor of α4β1 and α4β7 integrins
US6210904B1 (en) 1997-10-14 2001-04-03 Merck & Co., Inc. Anticoagulant test
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US6087332A (en) * 1997-12-23 2000-07-11 Galler; Lawrence Isaac Streptokinase derivatives with high affinity for activated platelets and methods of their production and use in thrombolytic therapy
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EP1322322A4 (en) * 2000-09-11 2005-04-06 Univ Temple COMPOUNDS AND METHODS FOR INHIBITING INTEGRINS ALPHA-1 BETA-1
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US7691968B2 (en) * 2002-05-03 2010-04-06 Avecia Biologics Limited Process for the synthesis of peptides amides by side-chain attachment to a solid phase
RU2524129C2 (ru) * 2003-01-10 2014-07-27 Аблинкс Н.В. Терапевтические полипептиды, их гомологи, их фрагменты и их применение для модуляции агрегации, опосредованной тромбоцитами
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US7723474B2 (en) * 2003-10-21 2010-05-25 The Regents Of The University Of California Molecules that selectively home to vasculature of pre-malignant dysplastic lesions or malignancies
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US7566701B2 (en) * 2004-09-07 2009-07-28 Archemix Corp. Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics
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WO2008020743A2 (fr) * 2006-08-16 2008-02-21 Wisdom Asset Company Procédé permettant d'extraire un inhibiteur de l'agrégation plaquettaire du venin d'agkistrodon blomhoffii ussuriensis
WO2008150495A2 (en) * 2007-06-01 2008-12-11 Archemix Corp. Vwf aptamer formulations and methods for use
GB2462022B (en) 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods thereof
CA2804926C (en) 2010-07-09 2019-01-08 James Trinca Green Combination immediate/delayed release delivery system for short half-life pharmaceuticals including remogliflozin
RU2444731C1 (ru) * 2010-10-06 2012-03-10 Российская Федерация, от имени которой выступает Министерство образования и науки Российской Федерации (Минобрнауки России) Способ выравнивания хроматограмм пептидных смесей
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Also Published As

Publication number Publication date
ATE146969T1 (de) 1997-01-15
DE69029579D1 (de) 1997-02-13
DK0477295T3 (da) 1997-07-07
NO982249L (no) 1992-01-31
NO312965B1 (no) 2002-07-22
WO1990015620A1 (en) 1990-12-27
NO982249D0 (no) 1998-05-15
ES2097150T3 (es) 1997-04-01
NO304267B1 (no) 1998-11-23
AU636159B2 (en) 1993-04-22
EP0477295B1 (en) 1997-01-02
LU90488I2 (fr) 2000-02-15
CA2059124C (en) 2002-08-20
FI104364B (fi) 2000-01-14
DE69029579T3 (de) 2006-06-22
EP0477295A1 (en) 1992-04-01
NL990043I1 (nl) 2000-02-01
AU6036990A (en) 1991-01-08
DE69029579T2 (de) 1997-07-24
US5318899A (en) 1994-06-07
US5958732A (en) 1999-09-28
HU216318B (hu) 1999-06-28
US5496724A (en) 1996-03-05
DK0477295T4 (da) 2005-12-12
KR0180918B1 (ko) 1999-04-01
CA2388770A1 (en) 1990-12-27
NL990043I2 (nl) 2000-04-03
HU905490D0 (en) 1992-03-30
RU2156468C2 (ru) 2000-09-20
HUT59835A (en) 1992-07-28
KR920702627A (ko) 1992-10-06
DE19975072I2 (de) 2011-01-20
JP3281370B2 (ja) 2002-05-13
NO914962D0 (no) 1991-12-16
CA2059124A1 (en) 1990-12-17
NO2000008I2 (no) 2006-01-16
EP0477295A4 (en) 1992-10-07
FI915919A0 (fi) 1991-12-16
EP0751219A1 (en) 1997-01-02
EP0477295B2 (en) 2005-11-16
DE19975072I1 (de) 2000-03-09
JPH05500750A (ja) 1993-02-18
ES2097150T5 (es) 2006-06-16
US5736339A (en) 1998-04-07

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