NO965403L - Mikropartikler for frigjöring av aktive preparat - Google Patents

Mikropartikler for frigjöring av aktive preparat

Info

Publication number
NO965403L
NO965403L NO965403A NO965403A NO965403L NO 965403 L NO965403 L NO 965403L NO 965403 A NO965403 A NO 965403A NO 965403 A NO965403 A NO 965403A NO 965403 L NO965403 L NO 965403L
Authority
NO
Norway
Prior art keywords
microparticles
pct
biodegradable
emulsion
sec
Prior art date
Application number
NO965403A
Other languages
English (en)
Other versions
NO965403D0 (no
NO317348B1 (no
Inventor
Ming-Kung Yeh
Alan G A Coombes
Paul G Jenkins
Stanley S Davis
Original Assignee
Univ Nottingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nottingham filed Critical Univ Nottingham
Publication of NO965403D0 publication Critical patent/NO965403D0/no
Publication of NO965403L publication Critical patent/NO965403L/no
Publication of NO317348B1 publication Critical patent/NO317348B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO19965403A 1994-06-18 1996-12-16 Mikropartikler for frigjoring av aktive preparat NO317348B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9412273A GB9412273D0 (en) 1994-06-18 1994-06-18 Administration means
PCT/GB1995/001426 WO1995035097A1 (en) 1994-06-18 1995-06-19 Polymer microparticles for drug delivery

Publications (3)

Publication Number Publication Date
NO965403D0 NO965403D0 (no) 1996-12-16
NO965403L true NO965403L (no) 1996-12-16
NO317348B1 NO317348B1 (no) 2004-10-18

Family

ID=10756962

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19965403A NO317348B1 (no) 1994-06-18 1996-12-16 Mikropartikler for frigjoring av aktive preparat

Country Status (11)

Country Link
US (1) US5869103A (no)
EP (1) EP0766554B1 (no)
JP (1) JP2963540B2 (no)
AT (1) ATE293437T1 (no)
AU (1) AU689272B2 (no)
CA (1) CA2193203C (no)
DE (1) DE69534163D1 (no)
FI (1) FI965068A (no)
GB (1) GB9412273D0 (no)
NO (1) NO317348B1 (no)
WO (1) WO1995035097A1 (no)

Families Citing this family (152)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612052A (en) * 1995-04-13 1997-03-18 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US6413539B1 (en) 1996-10-31 2002-07-02 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
GB9514285D0 (en) * 1995-07-13 1995-09-13 Univ Nottingham Polymeric lamellar substrate particles for drug delivery
GB2317340B (en) * 1995-07-13 1998-12-23 Danbiosyst Uk Polymeric lamellar substrate particles for drug delivery
US6143211A (en) 1995-07-21 2000-11-07 Brown University Foundation Process for preparing microparticles through phase inversion phenomena
CA2227287A1 (en) 1995-07-21 1997-02-06 Brown University Research Foundation A method for gene therapy using nucleic acid loaded polymeric microparticles
US6248720B1 (en) 1996-07-03 2001-06-19 Brown University Research Foundation Method for gene therapy using nucleic acid loaded polymeric microparticles
US6270795B1 (en) * 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
EP0965336A1 (en) 1995-11-09 1999-12-22 Microbiological Research Authority Microencapsulated DNA for gene therapy
GB9709900D0 (en) * 1997-05-15 1997-07-09 Microbiological Res Authority Microencapsulated DNA for vaccination and gene therapy
GB9600272D0 (en) * 1996-01-06 1996-03-06 Univ Nottingham Polymers
NZ325561A (en) * 1996-01-24 1999-06-29 Us Army Pharmaceutical composition containing an active ingredient and poly(lactide/glycolide) microcapsules which is a burst free controlled release formulation
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6303300B1 (en) * 1996-08-16 2001-10-16 Introgen B.V. Poly (organo) phosphazenes for use in synthetic transfection systems
EP1498115A1 (en) * 1997-01-16 2005-01-19 Massachusetts Institute Of Technology Preparation of particles for inhalation
EP0954282B1 (en) * 1997-01-16 2005-01-19 Massachusetts Institute Of Technology Preparation of particles for inhalation
US20020182258A1 (en) * 1997-01-22 2002-12-05 Zycos Inc., A Delaware Corporation Microparticles for delivery of nucleic acid
US5783567A (en) * 1997-01-22 1998-07-21 Pangaea Pharmaceuticals, Inc. Microparticles for delivery of nucleic acid
AU724294B2 (en) * 1997-01-22 2000-09-14 Eisai Inc. Microparticles for delivery of nucleic acid
NZ337054A (en) * 1997-01-30 2001-03-30 Chiron Corp Microparticles PLA and PLG with adsorbed viral antigen to stimulate immune responses particularly for intracellular viruses such as HSV-1 or HSV-2, varicella zoster virus. epstein-barr virus or cytomegalovirus (CMV)
US6884435B1 (en) * 1997-01-30 2005-04-26 Chiron Corporation Microparticles with adsorbent surfaces, methods of making same, and uses thereof
US20040202680A1 (en) * 1997-01-30 2004-10-14 O'hagan Derek Microparticles with adsorbent surfaces, methods of making same, and uses thereof
US5912225A (en) 1997-04-14 1999-06-15 Johns Hopkins Univ. School Of Medicine Biodegradable poly (phosphoester-co-desaminotyrosyl L-tyrosine ester) compounds, compositions, articles and methods for making and using the same
US6833275B1 (en) * 1997-07-22 2004-12-21 Roche Diagnostics Gmbh Gold conjugates containing detergent
CA2302569A1 (en) * 1997-09-05 1999-03-18 Maruho Kabushikikaisha Nanocapsule preparation for treatment of intra-articular diseases
US20040265377A1 (en) * 1997-10-27 2004-12-30 Harry Seager Solid dispersing vaccine composition for oral delivery
WO1999030737A1 (en) * 1997-12-16 1999-06-24 Chiron Corporation Use of microparticles combined with submicron oil-in-water emulsions
US7393630B2 (en) * 1997-12-16 2008-07-01 Novartis Vaccines And Diagnostics, Inc. Use of microparticles combined with submicron oil-in-water emulsions
US20030180368A1 (en) * 1998-03-14 2003-09-25 Cenes Drug Delivery Limited Production of microparticles
US6406719B1 (en) 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
EP1096957A1 (en) 1998-06-18 2001-05-09 Johns Hopkins University School of Medicine Methods and reagents for intramuscular delivery of nucleic acids
US6916490B1 (en) 1998-07-23 2005-07-12 UAB Research Center Controlled release of bioactive substances
KR100348397B1 (ko) * 1998-08-18 2003-01-24 김호연 경구관용유도용조성물
US7087236B1 (en) 1998-09-01 2006-08-08 Merrion Research I Limited Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
JP2002524741A (ja) * 1998-09-04 2002-08-06 パウダージェクト リサーチ リミテッド 粒子送達方法を使用する免疫診断
US6565874B1 (en) 1998-10-28 2003-05-20 Atrix Laboratories Polymeric delivery formulations of leuprolide with improved efficacy
US6143314A (en) 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst
GB9905136D0 (en) * 1999-03-06 1999-04-28 Danbiosyst Uk Surface modification of lamellar particles
WO2000072893A2 (en) * 1999-05-27 2000-12-07 Monsanto Company Biomaterials modified with superoxide dismutase mimics
US20040110722A1 (en) * 1999-05-27 2004-06-10 Ornberg Richard L. Modified hyaluronic acid polymers
US7030097B1 (en) 1999-07-14 2006-04-18 Cornell Research Foundation, Inc. Controlled nucleic acid delivery systems
AU6510400A (en) * 1999-08-04 2001-03-05 Oakwood Laboratories L.L.C. Slow release microspheres
US6503528B1 (en) * 1999-11-19 2003-01-07 Abbott Laboratories Polymeric compositions and a method of making the same
US20030206958A1 (en) * 2000-12-22 2003-11-06 Cattaneo Maurizio V. Chitosan biopolymer for the topical delivery of active agents
WO2001047572A2 (en) * 1999-12-29 2001-07-05 Advanced Cardiovascular Systems, Inc. Device and active component for inhibiting formation of thrombus-inflammatory cell matrix
AU2001264706A1 (en) * 2000-05-19 2001-12-03 Battelle Memorial Institute Controlled release of materials from polymer matrices
US20040022814A1 (en) * 2000-06-15 2004-02-05 O'hagan Derek Microparticles with adsorbent surfaces, methods of making same, and uses thereof
FR2811227A1 (fr) * 2000-07-07 2002-01-11 Philippe Maincent Vecteurs particulaires destines a ameliorer l'absorption orale de principes actifs
US6565888B1 (en) 2000-08-23 2003-05-20 Alkermes Controlled Therapeutics, Inc. Methods and compositions for the targeted delivery of biologically active agents
CN1468089B (zh) * 2000-09-28 2011-09-21 诺华疫苗和诊断公司 用于传送异源核酸的微粒体
BR0114304A (pt) * 2000-09-28 2003-07-29 Chiron Corp Composições de micropartìculas e métodos para a manufatura das mesmas
US8470359B2 (en) 2000-11-13 2013-06-25 Qlt Usa, Inc. Sustained release polymer
EP1423175B1 (en) 2001-08-08 2013-10-02 Brown University Research Foundation Methods for micronization of hydrophobic drugs
US7309498B2 (en) * 2001-10-10 2007-12-18 Belenkaya Bronislava G Biodegradable absorbents and methods of preparation
CA2466998A1 (en) * 2001-11-12 2003-05-22 Alkermes Controlled Therapeutics, Inc. Biocompatible polymer blends and uses thereof
US20060177495A1 (en) * 2001-12-21 2006-08-10 Christine Allen Polymer-lipid delivery vehicles
US20030235619A1 (en) * 2001-12-21 2003-12-25 Christine Allen Polymer-lipid delivery vehicles
JP4679822B2 (ja) * 2002-03-13 2011-05-11 ノバルティス アーゲー 医薬微粒子
EP1344520B1 (en) * 2002-03-15 2007-10-03 Alrise Biosystems GmbH Microparticles and method for their production
US8728510B1 (en) 2002-03-15 2014-05-20 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing a bioadhesive material
CA2479920A1 (en) * 2002-03-29 2003-10-09 The Regents Of The University Of California Microgel particles for the delivery of bioactive materials
AU2003217531A1 (en) * 2002-05-02 2003-11-17 Massachusetts Eye And Ear Infirmary Ocular drug delivery systems and use thereof
MXPA05002589A (es) * 2002-09-05 2005-09-20 Ambrose Catherine G Microesferas antibioticas para el tratamiento de infecciones y osteomelitis.
US8986737B2 (en) * 2002-09-05 2015-03-24 Wm. Marsh Rice University Antibiotic microspheres for treatment and prevention of osteomyelitis and enhancement of bone regrowth
FR2850880B1 (fr) * 2003-02-07 2006-06-23 Cerexagri Fabrication de microbilles de pesticides et utilisation de ces microbilles dans la protection des cultures
US20070207211A1 (en) * 2003-04-10 2007-09-06 Pr Pharmaceuticals, Inc. Emulsion-based microparticles and methods for the production thereof
AU2004253853B2 (en) 2003-04-10 2010-04-01 Evonik Corporation A method for the production of emulsion-based micro particles
WO2004105791A2 (en) * 2003-06-02 2004-12-09 The Talwar Research Foundation Recombinant anti-lhrh vaccines
ES2596553T3 (es) * 2003-06-02 2017-01-10 Glaxosmithkline Biologicals Sa Composiciones inmunogénicas a base de micropartículas que comprenden toxoide adsorbido y un antígeno que contiene un polisacárido
ES2741576T3 (es) * 2003-07-23 2020-02-11 Evonik Corp Composiciones de liberación controlada
US20060263350A1 (en) * 2003-09-26 2006-11-23 Fairfield Clinical Trials Llc Combination antihistamine medication
EP1704585B1 (en) 2003-12-19 2017-03-15 The University Of North Carolina At Chapel Hill Methods for fabricating isolated micro- and nano- structures using soft or imprint lithography
US9040090B2 (en) 2003-12-19 2015-05-26 The University Of North Carolina At Chapel Hill Isolated and fixed micro and nano structures and methods thereof
WO2007030698A2 (en) * 2005-09-07 2007-03-15 The University Of North Carolina At Chapel Hill Materials and methods for fabricating isolated micro-and nano-structures having chemical functionality
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US20050281886A1 (en) * 2004-05-06 2005-12-22 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents
EP1786443B1 (en) 2004-07-19 2018-06-06 Celator Pharmaceuticals, Inc. Particulate constructs for release of active agents
US20060057215A1 (en) * 2004-09-15 2006-03-16 Raiche Adrian T Method for the production of nanoparticles and microparticles by ternary agent concentration and temperature alteration induced immiscibility
WO2007001448A2 (en) * 2004-11-04 2007-01-04 Massachusetts Institute Of Technology Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
KR20080018178A (ko) * 2005-05-06 2008-02-27 후지필름 가부시키가이샤 나노입자의 농축 방법 및 응집 나노입자의 분산 방법
US9267937B2 (en) * 2005-12-15 2016-02-23 Massachusetts Institute Of Technology System for screening particles
JP2009534309A (ja) 2006-03-31 2009-09-24 マサチューセッツ インスティテュート オブ テクノロジー 治療剤の標的化送達のためのシステム
CA2652280C (en) * 2006-05-15 2014-01-28 Massachusetts Institute Of Technology Polymers for functional particles
WO2007137117A2 (en) * 2006-05-17 2007-11-29 Massachusetts Institute Of Technology Aptamer-directed drug delivery
US9381477B2 (en) * 2006-06-23 2016-07-05 Massachusetts Institute Of Technology Microfluidic synthesis of organic nanoparticles
WO2008011051A1 (en) * 2006-07-17 2008-01-24 Liquidia Technologies, Inc. Nanoparticle fabrication methods, systems, and materials
WO2008013952A2 (en) 2006-07-27 2008-01-31 The University Of North Carolina At Chapel Hill Nanoparticle fabrication methods, systems, and materials for fabricating artificial red blood cells
WO2008019142A2 (en) * 2006-08-04 2008-02-14 Massachusetts Institute Of Technology Oligonucleotide systems for targeted intracellular delivery
US8039010B2 (en) 2006-11-03 2011-10-18 Allergan, Inc. Sustained release intraocular drug delivery systems comprising a water soluble therapeutic agent and a release modifier
US9217129B2 (en) * 2007-02-09 2015-12-22 Massachusetts Institute Of Technology Oscillating cell culture bioreactor
US20100151031A1 (en) * 2007-03-23 2010-06-17 Desimone Joseph M Discrete size and shape specific organic nanoparticles designed to elicit an immune response
WO2008117313A1 (en) * 2007-03-28 2008-10-02 National Institute Of Immunology Polymer particles based vaccine
WO2008124639A2 (en) * 2007-04-04 2008-10-16 Massachusetts Institute Of Technology Poly (amino acid) targeting moieties
WO2008124634A1 (en) * 2007-04-04 2008-10-16 Massachusetts Institute Of Technology Polymer-encapsulated reverse micelles
EP2044934A1 (en) * 2007-10-01 2009-04-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Dispersion of poloxamer-protein particles, methods of manufacturing and uses thereof
CA3014633C (en) * 2007-10-08 2022-05-17 Aurinia Pharmaceuticals Inc. Ophthalmic compositions comprising calcineurin inhibitors or mtor inhibitors
EP3424525A1 (en) 2007-10-12 2019-01-09 Massachusetts Institute Of Technology Vaccine nanotechnology
CA2709712C (en) 2007-12-20 2016-05-10 Surmodics Pharmaceuticals, Inc. Process for preparing microparticles having a low residual solvent volume
US8613951B2 (en) 2008-06-16 2013-12-24 Bind Therapeutics, Inc. Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
KR101706178B1 (ko) 2008-06-16 2017-02-15 화이자 인코포레이티드 약물 부하된 중합체성 나노입자, 및 이의 제조 및 사용 방법
JP2012501966A (ja) 2008-06-16 2012-01-26 バインド バイオサイエンシズ インコーポレイテッド ビンカアルカロイド含有治療用ポリマーナノ粒子並びにその製造方法及び使用方法
WO2010001932A1 (ja) * 2008-07-01 2010-01-07 日東電工株式会社 表面被覆微粒子の医薬組成物
US20100087337A1 (en) * 2008-09-10 2010-04-08 Bind Biosciences, Inc. High Throughput Fabrication of Nanoparticles
US8343498B2 (en) 2008-10-12 2013-01-01 Massachusetts Institute Of Technology Adjuvant incorporation in immunonanotherapeutics
US8591905B2 (en) * 2008-10-12 2013-11-26 The Brigham And Women's Hospital, Inc. Nicotine immunonanotherapeutics
US8343497B2 (en) 2008-10-12 2013-01-01 The Brigham And Women's Hospital, Inc. Targeting of antigen presenting cells with immunonanotherapeutics
US8277812B2 (en) 2008-10-12 2012-10-02 Massachusetts Institute Of Technology Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
WO2010068866A2 (en) 2008-12-12 2010-06-17 Bind Biosciences Therapeutic particles suitable for parenteral administration and methods of making and using same
EP2379064B1 (en) 2008-12-15 2020-02-26 Pfizer Inc. Long circulating nanoparticles for sustained release of therapeutic agents
JP2012515837A (ja) * 2009-01-23 2012-07-12 サーモディクス ファーマシューティカルズ, インコーポレイテッド 異なる非反復単位を有するポリマーを含むポリマー混合物、ならびにそれを作製および使用するための方法
EP2389161A2 (en) * 2009-01-23 2011-11-30 Surmodics Pharmaceuticals, Inc. Controlled release systems from polymer blends
JP2012524780A (ja) * 2009-04-21 2012-10-18 セレクタ バイオサイエンシーズ インコーポレーテッド Th1バイアス応答をもたらす免疫ナノ治療薬(Immunonanotherapeutics)
US20110020388A1 (en) 2009-05-27 2011-01-27 Selecta Biosciences, Inc. Targeted synthetic nanocarriers with ph sensitive release of immunomodulatory agents
WO2010144194A1 (en) * 2009-06-09 2010-12-16 Lux Biosciences, Inc. Topical drug delivery systems for ophthalmic use
DK2509634T3 (en) 2009-12-11 2019-04-23 Pfizer Stable formulations for lyophilization of therapeutic particles
WO2011084513A2 (en) 2009-12-15 2011-07-14 Bind Biosciences, Inc. Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers
EP2516053B1 (en) * 2009-12-22 2019-11-20 Evonik Corporation Emulsion-based process for preparing microparticles and workhead assembly for use with same
WO2011119262A1 (en) 2010-03-26 2011-09-29 Cerulean Pharma Inc. Methods and systems for generating nanoparticles
US20110262491A1 (en) * 2010-04-12 2011-10-27 Selecta Biosciences, Inc. Emulsions and methods of making nanocarriers
BR112012029823A2 (pt) 2010-05-26 2020-09-01 Selecta Biosciences, Inc. seleção da dose de nanoveículos sintéticos adjuvantados
WO2012103182A1 (en) 2011-01-28 2012-08-02 Cerulean Pharma Inc. Method for fabricating nanoparticles
CA2838481A1 (en) * 2011-07-27 2013-01-31 Polypid Ltd. Matrix compositions for controlled release of peptide and polypeptide molecules
CN109172819A (zh) 2011-07-29 2019-01-11 西莱克塔生物科技公司 产生体液和细胞毒性t淋巴细胞(ctl)免疫应答的合成纳米载体
US9877923B2 (en) 2012-09-17 2018-01-30 Pfizer Inc. Process for preparing therapeutic nanoparticles
ES2737692T3 (es) 2014-03-14 2020-01-15 Pfizer Nanopartículas terapéuticas que comprenden un agente terapéutico y procedimientos de fabricación y uso de las mismas
CN107278151A (zh) 2014-12-15 2017-10-20 约翰霍普金斯大学 舒尼替尼制剂及其在治疗青光眼中的使用方法
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
EP3340982B1 (en) 2015-08-26 2021-12-15 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
US10953103B2 (en) 2015-11-06 2021-03-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V Composition comprising a biocompatible and biodegradable polymer, nanocarriers and a drug and methods of making and using the same
MX2018005932A (es) 2015-11-12 2019-05-20 Graybug Vision Inc Microparticulas aglomerantes para terapia medica.
EP3455218A4 (en) 2016-05-10 2019-12-18 C4 Therapeutics, Inc. C3 CARBON-BASED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION
EP3454862B1 (en) 2016-05-10 2024-09-11 C4 Therapeutics, Inc. Spirocyclic degronimers for target protein degradation
WO2017197055A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Heterocyclic degronimers for target protein degradation
AU2017290593A1 (en) 2016-06-27 2019-01-03 Achillion Pharmaceuticals, Inc. Quinazoline and indole compounds to treat medical disorders
CN109789143A (zh) 2016-07-01 2019-05-21 G1治疗公司 基于嘧啶的抗增殖剂
ES2907847T3 (es) * 2016-09-30 2022-04-26 Mati Therapeutics Inc Formulación de liberación sostenida de fármaco oftálmico y sus usos
KR20240019857A (ko) 2017-03-01 2024-02-14 아칠리온 파르마세우티칼스 인코포레이티드 의학적 장애의 치료를 위한 아릴, 헤테로아릴, 및 헤테로사이클릭 약학적 화합물
EP3600324A4 (en) 2017-03-23 2020-12-09 Graybug Vision, Inc. COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS
BR112019022908A2 (pt) 2017-05-10 2020-05-26 Graybug Vision, Inc. Micropartícula de agregação sólida, sólido liofilizado ou reconstituível de micropartículas de agregação, método para tratamento de um distúrbio ocular, e, uso das micropartículas de agregação sólidas
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
JP2021519337A (ja) 2018-03-26 2021-08-10 シー4 セラピューティクス, インコーポレイテッド Ikarosの分解のためのセレブロン結合剤
JP7538113B2 (ja) 2018-08-20 2024-08-21 アキリオン ファーマシューティカルズ,インコーポレーテッド 補体d因子の医学的障害の治療のための医薬化合物
US20220088150A1 (en) * 2018-09-20 2022-03-24 Biovena Science, Llc Octreotide Microsphere-Based Arterial Embolization for Treating Obesity
WO2020081723A1 (en) 2018-10-16 2020-04-23 Georgia State University Research Foundation, Inc. Carbon monoxide prodrugs for the treatment of medical disorders
US20220241204A1 (en) * 2019-06-07 2022-08-04 Diomics Corporation Topical time release delivery using layered biopolymer
JP2021028305A (ja) 2019-08-09 2021-02-25 株式会社リコー 粒子、医薬組成物、及び粒子の製造方法
US11980636B2 (en) 2020-11-18 2024-05-14 Jazz Pharmaceuticals Ireland Limited Treatment of hematological disorders
CN114159411A (zh) * 2021-10-21 2022-03-11 广东省科学院健康医学研究所 一种载药聚合物微球及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
DE3378250D1 (en) * 1982-04-22 1988-11-24 Ici Plc Continuous release formulations
DE3916020C2 (de) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retardierende Mikropartikel aus bioabbaubaren Polyestern; Verfahren zu deren Herstellung unter Verzicht auf toxische Lösungsmittel und diese Mikropartikel enthaltende pharmazentische Zubereitungen
IT1243390B (it) * 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
US5543158A (en) * 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles

Also Published As

Publication number Publication date
JPH09510477A (ja) 1997-10-21
AU2743695A (en) 1996-01-15
FI965068A (fi) 1997-02-17
US5869103A (en) 1999-02-09
CA2193203A1 (en) 1995-12-28
EP0766554A1 (en) 1997-04-09
DE69534163D1 (de) 2005-05-25
EP0766554B1 (en) 2005-04-20
JP2963540B2 (ja) 1999-10-18
AU689272B2 (en) 1998-03-26
CA2193203C (en) 2000-12-05
NO965403D0 (no) 1996-12-16
ATE293437T1 (de) 2005-05-15
NO317348B1 (no) 2004-10-18
FI965068A0 (fi) 1996-12-17
GB9412273D0 (en) 1994-08-10
WO1995035097A1 (en) 1995-12-28

Similar Documents

Publication Publication Date Title
NO965403L (no) Mikropartikler for frigjöring av aktive preparat
FI921351A (fi) Laktonpolymerisation som katalyserats med yttrium och saellsynta jordmetalloxidfoereningar.
DE60014400D1 (de) Antiadhäsionsschicht aus hyaluronsäure
ATE221373T1 (de) Verfahren zur herstellung von präparaten mit kontrollierter wirkstofffreisetzung auf basis von polymeren
NO984923D0 (no) Sure polymelkesyrepolymerer
ES2172574T3 (es) Preparacion de microparticulas biodegradables que contienen un agente biologicamente activo.
DK0643963T3 (da) Biologisk nedbrydelig indretning til indgivelse af virksomme stoffer
ATE240718T1 (de) Verfahren zur herstellung von arzneiformen mit kontrollierter wirkstoffabgabe auf polymerbasis
ES2110544T3 (es) Procedimiento para la fabricacion de una preparacion a base de microesferas de liberacion sostenida.
BRPI0213564B8 (pt) formulação depósito e micropartícula compreendendo iloperidona e polímero poli(d,l-lactídeo-co-glicolídeo), e processo para preparação da referida micropartícula
NO991011L (no) Fast skumpreparater med aktiv bestandel og fremgangsmÕte for fremstilling derav
ATE163230T1 (de) Makromolekulare mikropartikel und verfahren zu ihrer herstellung
ATE405251T1 (de) Zusammensetzungen zur verzögerten abgabe von hydrophoben arzneimitteln und verfahren zu ihrer herstellung
DE69914787D1 (de) Flüssige zusammensetzungen mit kontrollierter freigabe mit niedrigem initialfreisetzungsstoss des wirkstoffs
WO2001068052A3 (en) Phosphate based biodegradable polymers
DE59909717D1 (de) Verfahren zur Herstellung von festen Dosierungsformen
AR018451A1 (es) Composiciones para el cuidado de cabello y metodo para depositar particulas de polimeros expandidos sobre el cabello
BR0014472A (pt) Processo e dispositivo para a preparação contìnua de uma mistura de polìmeros termoplástica e sua aplicação
ATE326950T1 (de) Verfahren zur herstellung von zusammensetzungen mit beschleunigter abgabe unter verwendung von komprimierten fluiden
BR0013346B1 (pt) mÉtodo para inibir polimerizaÇço prematura de monâmero vinil-aromÁtico e composiÇço.
GB2303551A (en) Polymer microparticles for drug delivery
BR9606353A (pt) Processo para a preparaç o de uma resina desodorizada para um toner seco
DE69026312D1 (de) Verfahren zur Herstellung von vernetztem Polybeta-alanin in einem einzigen Schritt aus Acrylamid und einer polyfunktionalen copolymerisierbaren Verbindung
DK1484033T3 (da) Flydende polymersammensætninger til kontrolleret frigivelse af bioaktive stoffer
ES2078182A1 (es) Procedimiento para la preparacion de microesferas biodegradables con liberacion controlada y microesferas correspondientes.