ATE326950T1 - Verfahren zur herstellung von zusammensetzungen mit beschleunigter abgabe unter verwendung von komprimierten fluiden - Google Patents
Verfahren zur herstellung von zusammensetzungen mit beschleunigter abgabe unter verwendung von komprimierten fluidenInfo
- Publication number
- ATE326950T1 ATE326950T1 AT01911742T AT01911742T ATE326950T1 AT E326950 T1 ATE326950 T1 AT E326950T1 AT 01911742 T AT01911742 T AT 01911742T AT 01911742 T AT01911742 T AT 01911742T AT E326950 T1 ATE326950 T1 AT E326950T1
- Authority
- AT
- Austria
- Prior art keywords
- active ingredient
- accelerated release
- compressed fluid
- preparing
- release compositions
- Prior art date
Links
- 239000012530 fluid Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 4
- 239000012296 anti-solvent Substances 0.000 abstract 2
- 229920006037 cross link polymer Polymers 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000005470 impregnation Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000MI000560A IT1318404B1 (it) | 2000-03-17 | 2000-03-17 | Processo per la preparazione di formulazioni a rilascio accelerato conimpiego di fluidi compressi. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE326950T1 true ATE326950T1 (de) | 2006-06-15 |
Family
ID=11444510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01911742T ATE326950T1 (de) | 2000-03-17 | 2001-03-07 | Verfahren zur herstellung von zusammensetzungen mit beschleunigter abgabe unter verwendung von komprimierten fluiden |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6913779B2 (de) |
| EP (1) | EP1267836B1 (de) |
| JP (1) | JP2003526653A (de) |
| KR (1) | KR20030070815A (de) |
| CN (1) | CN1418090A (de) |
| AT (1) | ATE326950T1 (de) |
| AU (1) | AU4068201A (de) |
| BR (1) | BR0109312A (de) |
| CA (1) | CA2403343C (de) |
| DE (1) | DE60119914D1 (de) |
| IT (1) | IT1318404B1 (de) |
| MX (1) | MXPA02009056A (de) |
| WO (1) | WO2001068054A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE416784T1 (de) * | 2000-12-01 | 2008-12-15 | Takeda Pharmaceutical | Verfahren zur herstellung einer zubereitung mit einer bioaktiven substanz |
| GB0126716D0 (en) * | 2001-11-07 | 2002-01-02 | Advanced Phytonics Ltd | Method for the production of particles |
| WO2003074028A1 (en) * | 2002-03-07 | 2003-09-12 | Eurand Pharmaceuticals Ltd. | Process for loading and thermodynamically activating drugs on polymers by means of supercritical fluids |
| GB0205868D0 (en) * | 2002-03-13 | 2002-04-24 | Univ Nottingham | Polymer composite with internally distributed deposition matter |
| US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| BRPI0720550A2 (pt) * | 2006-10-06 | 2014-07-08 | Newsouth Innovations Pty Ltd | Formação de partículas |
| GB0812742D0 (en) * | 2008-07-11 | 2008-08-20 | Critical Pharmaceuticals Ltd | Process |
| FR2945449B1 (fr) * | 2009-05-15 | 2012-10-05 | Pf Medicament | Procede d'impregnation par co2 supercritique |
| CA2765033C (en) | 2009-06-12 | 2020-07-14 | Meritage Pharma, Inc. | Methods for treating gastrointestinal disorders |
| CN105687141A (zh) * | 2016-03-04 | 2016-06-22 | 中国药科大学 | 超临界抗溶剂法制备尼美舒利-左旋聚乳酸(Nim-PLLA)复合微球的工艺研究 |
| CN110859807A (zh) * | 2018-08-28 | 2020-03-06 | 康芝药业股份有限公司 | 一种尼美舒利的固体分散微粉及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225192A (en) * | 1988-10-17 | 1993-07-06 | Vectorpharma International S.P.A. | Poorly soluble medicaments supported on polymer substances in a form suitable for increasing their dissolving rate |
| IE63321B1 (en) * | 1986-02-03 | 1995-04-05 | Elan Corp Plc | Drug delivery system |
| IT1230566B (it) * | 1988-10-17 | 1991-10-28 | Vectorpharma Int | Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione |
| CA2017332A1 (en) * | 1989-06-29 | 1990-12-29 | Richard W. Greiner | Pharmaceutically impregnated catheters |
| US5340614A (en) * | 1993-02-11 | 1994-08-23 | Minnesota Mining And Manufacturing Company | Methods of polymer impregnation |
| WO1996029998A1 (en) * | 1995-03-28 | 1996-10-03 | Fidia Advanced Biopolymers S.R.L. | Nanospheres comprising a biocompatible polysaccharide |
| IT1296464B1 (it) * | 1997-11-19 | 1999-06-25 | Vectorpharma Int | Composizioni farmaceutiche in forma di polveri di polimeri reticolati caricati con farmaci e relativo processo di preparazione mediante |
| WO2001087368A1 (en) * | 2000-05-16 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Process for coating medical devices using super-critical carbon dioxide |
-
2000
- 2000-03-17 IT IT2000MI000560A patent/IT1318404B1/it active
-
2001
- 2001-03-07 KR KR1020027011977A patent/KR20030070815A/ko not_active Withdrawn
- 2001-03-07 AT AT01911742T patent/ATE326950T1/de not_active IP Right Cessation
- 2001-03-07 JP JP2001566618A patent/JP2003526653A/ja active Pending
- 2001-03-07 DE DE60119914T patent/DE60119914D1/de not_active Expired - Lifetime
- 2001-03-07 AU AU40682/01A patent/AU4068201A/en not_active Abandoned
- 2001-03-07 WO PCT/EP2001/002538 patent/WO2001068054A1/en not_active Ceased
- 2001-03-07 MX MXPA02009056A patent/MXPA02009056A/es unknown
- 2001-03-07 CN CN01806649A patent/CN1418090A/zh active Pending
- 2001-03-07 BR BR0109312-6A patent/BR0109312A/pt not_active Application Discontinuation
- 2001-03-07 CA CA2403343A patent/CA2403343C/en not_active Expired - Fee Related
- 2001-03-07 US US10/221,704 patent/US6913779B2/en not_active Expired - Lifetime
- 2001-03-07 EP EP01911742A patent/EP1267836B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001068054A1 (en) | 2001-09-20 |
| CA2403343A1 (en) | 2001-09-20 |
| CN1418090A (zh) | 2003-05-14 |
| CA2403343C (en) | 2010-05-11 |
| US20030161957A1 (en) | 2003-08-28 |
| DE60119914D1 (de) | 2006-06-29 |
| ITMI20000560A1 (it) | 2001-09-17 |
| BR0109312A (pt) | 2002-12-17 |
| IT1318404B1 (it) | 2003-08-25 |
| US6913779B2 (en) | 2005-07-05 |
| AU4068201A (en) | 2001-09-24 |
| EP1267836A1 (de) | 2003-01-02 |
| MXPA02009056A (es) | 2004-09-06 |
| JP2003526653A (ja) | 2003-09-09 |
| EP1267836B1 (de) | 2006-05-24 |
| ITMI20000560A0 (it) | 2000-03-17 |
| KR20030070815A (ko) | 2003-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |