NO932872L - Nye 7-(substituerte)-8-(substituerte)-9-(substituert amino)-6-demetyl-6-deoksy-tetracykliner - Google Patents
Nye 7-(substituerte)-8-(substituerte)-9-(substituert amino)-6-demetyl-6-deoksy-tetracyklinerInfo
- Publication number
- NO932872L NO932872L NO932872A NO932872A NO932872L NO 932872 L NO932872 L NO 932872L NO 932872 A NO932872 A NO 932872A NO 932872 A NO932872 A NO 932872A NO 932872 L NO932872 L NO 932872L
- Authority
- NO
- Norway
- Prior art keywords
- substituted
- demethyl
- tetracyclines
- deoxy
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/10—Hydrazines
- C07C243/20—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
- C07C245/20—Diazonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
- C07C247/16—Compounds containing azido groups with azido groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C247/18—Compounds containing azido groups with azido groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/60—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups having oxygen atoms of carbamate groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
- C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Seasonings (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92859892A | 1992-08-13 | 1992-08-13 |
Publications (3)
Publication Number | Publication Date |
---|---|
NO932872D0 NO932872D0 (no) | 1993-08-12 |
NO932872L true NO932872L (no) | 1994-02-14 |
NO302568B1 NO302568B1 (no) | 1998-03-23 |
Family
ID=25456505
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO932872A NO302568B1 (no) | 1992-08-13 | 1993-08-12 | Nye 7-(substituerte)-8-(substituerte)-9-(substituert amino)-6-demetyl-6-deoksy-tetracykliner, farmasöytiske blandinger inneholdende disse og mellomprodukter i fremstillingen av dem |
Country Status (24)
Country | Link |
---|---|
US (4) | US5430162A (no) |
EP (1) | EP0582810B1 (no) |
JP (1) | JP3639313B2 (no) |
KR (1) | KR100309540B1 (no) |
CN (1) | CN1048719C (no) |
AT (1) | ATE215530T1 (no) |
AU (1) | AU674524B2 (no) |
CA (1) | CA2103861C (no) |
CZ (1) | CZ289195B6 (no) |
DE (1) | DE69331774T2 (no) |
DK (1) | DK0582810T3 (no) |
ES (1) | ES2173876T3 (no) |
FI (1) | FI933567A (no) |
HU (2) | HU213269B (no) |
IL (4) | IL119751A (no) |
NO (1) | NO302568B1 (no) |
NZ (1) | NZ248359A (no) |
PH (1) | PH31210A (no) |
PL (4) | PL174022B1 (no) |
PT (1) | PT582810E (no) |
RU (1) | RU2127255C1 (no) |
SG (1) | SG47520A1 (no) |
SK (1) | SK281871B6 (no) |
ZA (1) | ZA935892B (no) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5494903A (en) * | 1991-10-04 | 1996-02-27 | American Cyanamid Company | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
USRE40183E1 (en) | 1991-10-04 | 2008-03-25 | Wyeth Holdings Corporation | 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
US5442059A (en) * | 1992-08-13 | 1995-08-15 | American Cyanamid Company | 9-[(substituted glycyl)amido)]-6-demethyl-6-deoxytetracyclines |
US5248797A (en) * | 1992-08-13 | 1993-09-28 | American Cyanamid Company | Method for the production of 9-amino-6-demethyl-6-deoxytetracycline |
US5420272A (en) * | 1992-08-13 | 1995-05-30 | American Cyanamid Company | 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
SG47520A1 (en) * | 1992-08-13 | 1998-04-17 | American Cyanamid Co | New method for the production of 9-amino-6-demethyl-6-deoxytetracycline |
US6506740B1 (en) * | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
EP1666453A1 (en) * | 1999-09-14 | 2006-06-07 | Trustees Of Tufts College | Methods of preparing substituted tetracyclines with transition metal-based chemistries |
US6946118B1 (en) | 1999-09-14 | 2005-09-20 | Orapharma, Inc. | Formulations for treating or preventing mucositis |
US8106225B2 (en) * | 1999-09-14 | 2012-01-31 | Trustees Of Tufts College | Methods of preparing substituted tetracyclines with transition metal-based chemistries |
CA2404628A1 (en) * | 2000-03-31 | 2001-10-11 | Stuart B. Levy | 7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds |
CA2411342A1 (en) * | 2000-06-02 | 2001-12-13 | Yu Liu | Non-antibacterial tetracycline as anti-fungal agents |
WO2001098236A2 (en) * | 2000-06-16 | 2001-12-27 | Trustees Of Tufts College | 7-phenyl-substituted tetracycline compounds |
US20020132798A1 (en) * | 2000-06-16 | 2002-09-19 | Nelson Mark L. | 7-phenyl-substituted tetracycline compounds |
US6624168B2 (en) * | 2000-07-07 | 2003-09-23 | Trustees Of Tufts College | 7,8 and 9-substituted tetracycline compounds |
IL153639A0 (en) | 2000-07-07 | 2003-07-06 | Tufts College | 9-substituted minocycline compounds |
US7094806B2 (en) | 2000-07-07 | 2006-08-22 | Trustees Of Tufts College | 7, 8 and 9-substituted tetracycline compounds |
KR101083571B1 (ko) * | 2000-07-07 | 2011-11-14 | 파라테크 파마슈티컬스, 인크. | 7-치환 테트라사이클린 화합물 |
EP1241160A1 (en) | 2001-03-13 | 2002-09-18 | Glaxo Group Limited | Tetracycline derivatives and their use as antibiotic agents |
WO2002072506A2 (en) | 2001-03-13 | 2002-09-19 | Paratek Pharmaceuticals, Inc. | 7-pyrollyl tetracycline compounds and methods of use thereof |
EP1368305B1 (en) | 2001-03-13 | 2008-08-13 | Paratek Pharmaceuticals, Inc. | 7, 9-substituted tetracycline compounds |
US7553828B2 (en) | 2001-03-13 | 2009-06-30 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl substituted minocycline compounds |
US20040092490A1 (en) * | 2001-04-24 | 2004-05-13 | Michael Draper | Substituted tetracycline compounds for the treatment of malaria |
US20060194773A1 (en) * | 2001-07-13 | 2006-08-31 | Paratek Pharmaceuticals, Inc. | Tetracyline compounds having target therapeutic activities |
WO2003005971A2 (en) | 2001-07-13 | 2003-01-23 | Paratek Pharmaceuticals, Inc. | Tetracycline compounds having target therapeutic activities |
AU2002365120A1 (en) | 2001-08-02 | 2003-07-15 | Paratek Pharmaceuticals, Inc. | Medicaments |
EP2311798A1 (en) * | 2002-01-08 | 2011-04-20 | Paratek Pharmaceuticals, Inc. | 4-dedimethylamino tetracycline compounds |
KR101093842B1 (ko) * | 2002-03-08 | 2011-12-13 | 파라테크 파마슈티컬스, 인크. | 아미노-메틸 치환된 테트라시클린 화합물 |
CA2479877C (en) * | 2002-03-21 | 2012-08-21 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
KR20050005466A (ko) * | 2002-05-06 | 2005-01-13 | 콜라제넥스 파마슈티칼스, 인크 | 점막염 및 진균 감염을 동시에 치료하는 방법 |
AU2003256284A1 (en) * | 2002-06-20 | 2004-01-06 | Orapharma, Inc. | Rapidly disintegrating formulations for treating or preventing mucositis |
EA200900540A1 (ru) | 2002-07-12 | 2009-12-30 | Пэрэтек Фамэсьютикэлс, Инк. | Замещённые соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта |
EP1556007A4 (en) * | 2002-10-24 | 2008-12-17 | Paratek Pharm Innc | SUBSTITUTED TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF MALARIA |
US20060287283A1 (en) * | 2003-07-09 | 2006-12-21 | Paratek Pharmaceuticals, Inc. | Prodrugs of 9-aminomethyl tetracycline compounds |
CA2531728A1 (en) * | 2003-07-09 | 2005-02-03 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
JP5010284B2 (ja) * | 2004-01-15 | 2012-08-29 | パラテック ファーマシューティカルズ インコーポレイテッド | テトラサイクリン化合物の芳香族a環誘導体 |
PT1753713T (pt) | 2004-05-21 | 2016-11-08 | Harvard College | Síntese de tetraciclinas e seus análogos |
EP2287140A3 (en) | 2004-10-25 | 2011-09-21 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
JP2008518025A (ja) | 2004-10-25 | 2008-05-29 | パラテック ファーマシューティカルズ インコーポレイテッド | 4−アミノテトラサイクリンおよびその使用の方法 |
PA8652001A1 (es) | 2004-11-05 | 2006-10-13 | Wyeth Corp | Metabolitos glucuronidos de tigeciclina y epimeros de los mismos |
WO2006084265A1 (en) | 2005-02-04 | 2006-08-10 | Paratek Pharmaceuticals, Inc. | 11a, 12-DERIVATIVES OF TETRACYCLINE COMPOUNDS |
US20060183758A1 (en) * | 2005-02-17 | 2006-08-17 | Cb Research And Development, Inc. | Method for synthesis of AZA-annelated pyrroles, thiophenes, and furans |
AR057649A1 (es) | 2005-05-27 | 2007-12-12 | Wyeth Corp | Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas |
AR057032A1 (es) * | 2005-05-27 | 2007-11-14 | Wyeth Corp | Tigeciclina y metodos de preparacion |
AR057033A1 (es) * | 2005-05-27 | 2007-11-14 | Wyeth Corp | Tigeciclina y metodos para preparar 9-nitrominociclina |
AR057034A1 (es) * | 2005-05-27 | 2007-11-14 | Wyeth Corp | Metodos para purificar tigeciclina |
AR057324A1 (es) * | 2005-05-27 | 2007-11-28 | Wyeth Corp | Tigeciclina y metodos para preparar 9-aminominociclina |
CA2616224A1 (en) * | 2005-07-21 | 2007-02-01 | Paratek Pharmaceuticals, Inc. | 10-substituted tetracyclines and methods of use thereof |
AU2006331688A1 (en) * | 2005-12-22 | 2007-07-05 | Wyeth | Oral formulations comprising tigecycline |
BRPI0620430A2 (pt) * | 2005-12-22 | 2011-11-08 | Wyeth Corp | métodos para tratar infecções do trato gastrointestinal com tigeciclina |
JP2009543544A (ja) | 2006-05-15 | 2009-12-10 | パラテック ファーマシューティカルズ インコーポレイテッド | 置換されたテトラサイクリン化合物を用いて、遺伝子または遺伝子産物の発現を調節する方法 |
AR061485A1 (es) * | 2006-06-15 | 2008-08-27 | Serenex Inc | Composiciones estabilizadas de tetraciclina |
JP4729133B2 (ja) | 2007-11-29 | 2011-07-20 | アクテリオン ファーマシューティカルズ リミテッド | ホスホン酸誘導体及びp2y12受容体拮抗剤としてのそれらの使用 |
WO2010017470A1 (en) * | 2008-08-08 | 2010-02-11 | Tetraphase Pharmaceuticals, Inc. | C7-fluoro substituted tetracycline compounds |
EP2424834B1 (en) | 2009-04-30 | 2018-07-11 | President and Fellows of Harvard College | Synthesis of tetracyclines and intermediates thereof |
CN102459153A (zh) * | 2009-05-08 | 2012-05-16 | 四相制药公司 | 四环素类化合物 |
CN105622496B (zh) | 2009-08-28 | 2019-03-05 | 四相制药公司 | 四环素类化合物 |
CN108329312B (zh) | 2012-08-31 | 2021-12-31 | 四相制药公司 | 四环素化合物 |
CN110582486B (zh) | 2016-10-19 | 2024-01-12 | 四相制药公司 | 艾若威四环素的结晶形式 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE26271E (en) * | 1967-09-26 | Reductive alkylation process | ||
US2482055A (en) * | 1948-02-11 | 1949-09-13 | American Cyanamid Co | Aureomycin and preparation of same |
US3007965A (en) * | 1959-02-13 | 1961-11-07 | American Cyanamid Co | New tetracyclines produced by streptomyces aureofaciens |
US3043875A (en) * | 1959-10-22 | 1962-07-10 | Pfizer & Co C | Halogenated tetracycline derivatives and processes for their preparation |
FR1430859A (no) * | 1960-05-23 | 1966-05-25 | ||
US3338963A (en) * | 1960-10-28 | 1967-08-29 | American Cyanamid Co | Tetracycline compounds |
US3829453A (en) * | 1961-08-18 | 1974-08-13 | Pfizer | Octahydroanthracene-2-aminoacetic acids and esters and mixed anhydrides thereof |
US3360557A (en) * | 1963-05-10 | 1967-12-26 | American Cyanamid Co | 9-hydroxytetracyclines and a process of preparing same |
USRE26253E (en) * | 1963-05-17 | 1967-08-15 | And z-alkylamino-g-deoxytetracycline | |
US3341585A (en) * | 1966-05-06 | 1967-09-12 | American Cyanamid Co | Substituted 7-and/or 9-amino-6-deoxytetracyclines |
US3360561A (en) * | 1967-06-19 | 1967-12-26 | American Cyanamid Co | Nitration of tetracyclines |
US3518306A (en) * | 1968-02-19 | 1970-06-30 | American Cyanamid Co | 7- and/or 9-(n-nitrosoalkylamino)-6-demethyl-6-deoxytetracyclines |
US3579579A (en) * | 1968-04-18 | 1971-05-18 | American Cyanamid Co | Substituted 7- and/or 9-amino-6-demethyl-6-deoxytetracyclines |
US4806529A (en) * | 1982-11-18 | 1989-02-21 | Trustees Of Tufts College, Tufts University | Tetracycline activity enhancement |
US4518960A (en) * | 1982-11-23 | 1985-05-21 | Burroughs Corporation | Speed independent selector switch employing M-out-of-N codes |
US5328902A (en) * | 1992-08-13 | 1994-07-12 | American Cyanamid Co. | 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
US5284963A (en) * | 1992-08-13 | 1994-02-08 | American Cyanamid Company | Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines |
US5420272A (en) * | 1992-08-13 | 1995-05-30 | American Cyanamid Company | 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
SG47520A1 (en) * | 1992-08-13 | 1998-04-17 | American Cyanamid Co | New method for the production of 9-amino-6-demethyl-6-deoxytetracycline |
-
1993
- 1993-05-12 SG SG1996002634A patent/SG47520A1/en unknown
- 1993-06-21 DE DE69331774T patent/DE69331774T2/de not_active Expired - Fee Related
- 1993-06-21 EP EP93109850A patent/EP0582810B1/en not_active Expired - Lifetime
- 1993-06-21 PT PT93109850T patent/PT582810E/pt unknown
- 1993-06-21 ES ES93109850T patent/ES2173876T3/es not_active Expired - Lifetime
- 1993-06-21 DK DK93109850T patent/DK0582810T3/da active
- 1993-06-21 AT AT93109850T patent/ATE215530T1/de not_active IP Right Cessation
- 1993-08-04 CZ CZ19931575A patent/CZ289195B6/cs not_active IP Right Cessation
- 1993-08-09 NZ NZ248359A patent/NZ248359A/en unknown
- 1993-08-09 SK SK857-93A patent/SK281871B6/sk unknown
- 1993-08-11 JP JP21792793A patent/JP3639313B2/ja not_active Expired - Fee Related
- 1993-08-11 CA CA002103861A patent/CA2103861C/en not_active Expired - Fee Related
- 1993-08-12 IL IL11975193A patent/IL119751A/en not_active IP Right Cessation
- 1993-08-12 FI FI933567A patent/FI933567A/fi unknown
- 1993-08-12 PL PL93300066A patent/PL174022B1/pl not_active IP Right Cessation
- 1993-08-12 NO NO932872A patent/NO302568B1/no not_active IP Right Cessation
- 1993-08-12 PH PH46683A patent/PH31210A/en unknown
- 1993-08-12 PL PL93316768A patent/PL175487B1/pl not_active IP Right Cessation
- 1993-08-12 RU RU93048636A patent/RU2127255C1/ru not_active IP Right Cessation
- 1993-08-12 KR KR1019930015645A patent/KR100309540B1/ko not_active IP Right Cessation
- 1993-08-12 IL IL106677A patent/IL106677A/en not_active IP Right Cessation
- 1993-08-12 ZA ZA935892A patent/ZA935892B/xx unknown
- 1993-08-12 IL IL11975093A patent/IL119750A/en not_active IP Right Cessation
- 1993-08-12 PL PL93316767A patent/PL174230B1/pl not_active IP Right Cessation
- 1993-08-12 AU AU44601/93A patent/AU674524B2/en not_active Ceased
- 1993-08-12 PL PL93318908A patent/PL174127B1/pl not_active IP Right Cessation
- 1993-08-12 HU HU9302333A patent/HU213269B/hu not_active IP Right Cessation
- 1993-08-13 CN CN93109819A patent/CN1048719C/zh not_active Expired - Fee Related
-
1994
- 1994-03-21 US US08/214,992 patent/US5430162A/en not_active Expired - Lifetime
- 1994-12-08 US US08/352,407 patent/US5495018A/en not_active Expired - Lifetime
- 1994-12-08 US US08/352,310 patent/US5886175A/en not_active Expired - Fee Related
-
1995
- 1995-05-31 US US08/454,966 patent/US5512553A/en not_active Expired - Lifetime
- 1995-06-30 HU HU95P/P00672P patent/HU211303A9/hu unknown
-
1996
- 1996-12-03 IL IL11975096A patent/IL119750A0/xx unknown
Also Published As
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NO932871D0 (no) | Nye 7-(substituerte)-8-(substituerte)-9-((substituerte glycyl)amido)-6-demetyl-6-deoksytetracykliner | |
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