NO873426L - Fremgangsmaate for fremstilling av 1-(4-aminofenyl)-4-methyl-7,8-methylendioxy-3,4-dihydro-5h-2,3-benzodiazepin. - Google Patents

Fremgangsmaate for fremstilling av 1-(4-aminofenyl)-4-methyl-7,8-methylendioxy-3,4-dihydro-5h-2,3-benzodiazepin.

Info

Publication number
NO873426L
NO873426L NO873426A NO873426A NO873426L NO 873426 L NO873426 L NO 873426L NO 873426 A NO873426 A NO 873426A NO 873426 A NO873426 A NO 873426A NO 873426 L NO873426 L NO 873426L
Authority
NO
Norway
Prior art keywords
methylendioxy
benzodiazepine
aminophenyl
dihydro
methyl
Prior art date
Application number
NO873426A
Other languages
English (en)
Other versions
NO164656C (no
NO164656B (no
NO873426D0 (no
Inventor
Jeno Korosi
Tibor Lang
Ferenc Andrasi
Pal Berzsenyi
Peter Botka
Tamas Hamori
Katalin Goldschmidt
Jozsef Borsy
Istvan Elekes
Zsuzsa Lang
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Publication of NO873426D0 publication Critical patent/NO873426D0/no
Publication of NO873426L publication Critical patent/NO873426L/no
Publication of NO164656B publication Critical patent/NO164656B/no
Publication of NO164656C publication Critical patent/NO164656C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
NO873426A 1986-08-15 1987-08-14 Analogifremgangsmaate for fremstilling av terapeutisk aktivt 1-(4-amionfenyl)-4-methyl-7,8-methylendioxy-3,4-dihydro-5h-2,3-benzodiazepin. NO164656C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU863594A HU198494B (en) 1986-08-15 1986-08-15 Process for producing new 3,4-dihydro-5h-2,3-benzodiazepine derivative and acid addition salts thereof, as well as pharmaceutical compositions comprising same

Publications (4)

Publication Number Publication Date
NO873426D0 NO873426D0 (no) 1987-08-14
NO873426L true NO873426L (no) 1988-02-16
NO164656B NO164656B (no) 1990-07-23
NO164656C NO164656C (no) 1990-10-31

Family

ID=10964707

Family Applications (1)

Application Number Title Priority Date Filing Date
NO873426A NO164656C (no) 1986-08-15 1987-08-14 Analogifremgangsmaate for fremstilling av terapeutisk aktivt 1-(4-amionfenyl)-4-methyl-7,8-methylendioxy-3,4-dihydro-5h-2,3-benzodiazepin.

Country Status (23)

Country Link
US (1) US4835152A (no)
JP (1) JPS6399073A (no)
AT (1) ATA202187A (no)
AU (1) AU596206B2 (no)
BE (1) BE1002415A4 (no)
CA (1) CA1284322C (no)
CH (1) CH673652A5 (no)
CS (1) CS264150B2 (no)
DD (1) DD265627A5 (no)
DE (1) DE3727226A1 (no)
DK (1) DK164555C (no)
ES (1) ES2004985A6 (no)
FI (1) FI85706C (no)
FR (1) FR2602773B1 (no)
GB (1) GB2194236B (no)
HU (1) HU198494B (no)
IT (1) IT1222508B (no)
NL (1) NL8701909A (no)
NO (1) NO164656C (no)
PL (1) PL148535B1 (no)
RU (1) RU1779251C (no)
SE (1) SE467357B (no)
YU (1) YU46223B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
US5639751A (en) * 1990-12-21 1997-06-17 Cyogyszerkutato Intezet Kft N-acyl-2,3-benzodiazepine derivatives for treating acute and chronic neurodegenerative disorders
HU206719B (en) * 1990-12-21 1992-12-28 Gyogyszerkutato Intezet Process for producing 1-/4-acylamino-phenyl/-7,8-methylenedioxy-5h-2,3-benzodiazepine derivatives, acid addicional salts and pharmaceutical compositions containing them
US6329364B1 (en) * 1994-08-31 2001-12-11 Eli Lilly And Company Crystalline form of dihydro-2,3-benzodiazepine derivative
TR199501071A2 (tr) * 1994-08-31 1996-06-21 Lilly Co Eli Dihidro-2,3-benzodiazepin türevlerinin üretilmesi icin stereoselektif islem.
US5891871A (en) * 1996-03-21 1999-04-06 Cocensys, Inc. Substituted 2,3-benzodiazepin-4-ones and the use thereof
UA67749C2 (uk) 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
US6649607B2 (en) * 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US7745431B2 (en) * 2002-12-03 2010-06-29 Vela Acquisition Corporation Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5H-2,3-benzodiazepine and uses thereof
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
MXPA05005893A (es) * 2002-12-03 2006-02-08 Vela Pharmaceuticals Inc Composicion farmaceutica de 1-(3-hidroxi -4-metoxifenil) -4-metil-5 -etil-7, 8-dimetoxi- 5h-2, 3-benzodiazepina y usos de la misma.
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20070021412A1 (en) * 2003-05-16 2007-01-25 Vela Pharmaceuticals, Inc. Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (S) 2,3-benzodiazepine
JP4611308B2 (ja) * 2003-05-16 2011-01-12 ヴェラ アクイジション コーポレイション 鏡像的に純粋な（ｒ）２，３−ベンゾジアゼピンを使用する胃腸の機能不全及び関連するストレスの治療
US20040254173A1 (en) * 2003-06-13 2004-12-16 Leventer Steven M. Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines
US20050096464A1 (en) * 2003-10-30 2005-05-05 Heikki Heikkila Separation process
EP4197536A1 (en) * 2021-12-20 2023-06-21 Universitat de València Haloperidol for use in the treatment of spinal muscular atrophy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU186760B (en) * 1981-03-12 1985-09-30 Gyogyszerkutato Intezet Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
DE3319491A1 (de) * 1982-06-19 1983-10-13 Alps Electric Co., Ltd., Tokyo Papierfuehrungsmechanismus fuer schreibgeraete
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines

Also Published As

Publication number Publication date
RU1779251C (ru) 1992-11-30
NO164656C (no) 1990-10-31
YU46223B (sh) 1993-05-28
AU7688087A (en) 1988-02-18
DK164555B (da) 1992-07-13
ATA202187A (de) 1993-06-15
PL148535B1 (en) 1989-10-31
AU596206B2 (en) 1990-04-26
SE467357B (sv) 1992-07-06
CS264150B2 (en) 1989-06-13
DE3727226A1 (de) 1988-02-18
GB8719265D0 (en) 1987-09-23
NO164656B (no) 1990-07-23
GB2194236B (en) 1990-03-21
NL8701909A (nl) 1988-03-01
NO873426D0 (no) 1987-08-14
JPS6399073A (ja) 1988-04-30
DK424887D0 (da) 1987-08-14
DK164555C (da) 1992-11-30
FR2602773A1 (fr) 1988-02-19
HUT47287A (en) 1989-02-28
FI873525A (fi) 1988-02-16
SE8703169L (sv) 1988-02-16
FI85706C (fi) 1992-05-25
FI873525A0 (fi) 1987-08-14
IT1222508B (it) 1990-09-05
ES2004985A6 (es) 1989-02-16
DD265627A5 (de) 1989-03-08
FI85706B (fi) 1992-02-14
HU198494B (en) 1989-10-30
FR2602773B1 (fr) 1990-11-02
CH673652A5 (no) 1990-03-30
CS600787A2 (en) 1988-08-16
YU151487A (en) 1988-12-31
BE1002415A4 (fr) 1991-02-05
CA1284322C (en) 1991-05-21
US4835152A (en) 1989-05-30
SE8703169D0 (sv) 1987-08-14
IT8721667A0 (it) 1987-08-14
DK424887A (da) 1988-02-16
GB2194236A (en) 1988-03-02

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