FI873525A - Foerfarande foer framstaellning av ny, terapeutiskt anvaendbar 1-(4-aminofenyl)-4-metyl -7,8-metylendioxi-3,4-dihydro-5h-2,3-bensodiazepin och syraadditionssalter daerav. - Google Patents

Foerfarande foer framstaellning av ny, terapeutiskt anvaendbar 1-(4-aminofenyl)-4-metyl -7,8-metylendioxi-3,4-dihydro-5h-2,3-bensodiazepin och syraadditionssalter daerav. Download PDF

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Publication number
FI873525A
FI873525A FI873525A FI873525A FI873525A FI 873525 A FI873525 A FI 873525A FI 873525 A FI873525 A FI 873525A FI 873525 A FI873525 A FI 873525A FI 873525 A FI873525 A FI 873525A
Authority
FI
Finland
Prior art keywords
framstating
syraadditionssalter
anvaendbar
daerav
methylendioxy
Prior art date
Application number
FI873525A
Other languages
English (en)
Other versions
FI85706B (fi
FI85706C (fi
FI873525A0 (fi
Inventor
Jeno Koroesi
Tibor Lang
Ferenc Andrasi
Pal Berzsenyi
Peter Botka
Tamas Hamori
Nee Horvath Katali Goldschmidt
Jozsef Borsy
Istvan Elekes
Nee Rihmer Zsuzsa Lang
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Publication of FI873525A0 publication Critical patent/FI873525A0/fi
Publication of FI873525A publication Critical patent/FI873525A/fi
Publication of FI85706B publication Critical patent/FI85706B/fi
Application granted granted Critical
Publication of FI85706C publication Critical patent/FI85706C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
FI873525A 1986-08-15 1987-08-14 Foerfarande foer framstaellning av nytt terapeutiskt anvaendbart 1-(4-aminofenyl)-4-metyl -7,8-metylendioxi-3,4-dihydro-5h-2,3-bensodiazepin och syraadditionssalter daerav. FI85706C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU863594A HU198494B (en) 1986-08-15 1986-08-15 Process for producing new 3,4-dihydro-5h-2,3-benzodiazepine derivative and acid addition salts thereof, as well as pharmaceutical compositions comprising same
HU359486 1986-08-15

Publications (4)

Publication Number Publication Date
FI873525A0 FI873525A0 (fi) 1987-08-14
FI873525A true FI873525A (fi) 1988-02-16
FI85706B FI85706B (fi) 1992-02-14
FI85706C FI85706C (fi) 1992-05-25

Family

ID=10964707

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873525A FI85706C (fi) 1986-08-15 1987-08-14 Foerfarande foer framstaellning av nytt terapeutiskt anvaendbart 1-(4-aminofenyl)-4-metyl -7,8-metylendioxi-3,4-dihydro-5h-2,3-bensodiazepin och syraadditionssalter daerav.

Country Status (23)

Country Link
US (1) US4835152A (fi)
JP (1) JPS6399073A (fi)
AT (1) ATA202187A (fi)
AU (1) AU596206B2 (fi)
BE (1) BE1002415A4 (fi)
CA (1) CA1284322C (fi)
CH (1) CH673652A5 (fi)
CS (1) CS264150B2 (fi)
DD (1) DD265627A5 (fi)
DE (1) DE3727226A1 (fi)
DK (1) DK164555C (fi)
ES (1) ES2004985A6 (fi)
FI (1) FI85706C (fi)
FR (1) FR2602773B1 (fi)
GB (1) GB2194236B (fi)
HU (1) HU198494B (fi)
IT (1) IT1222508B (fi)
NL (1) NL8701909A (fi)
NO (1) NO164656C (fi)
PL (1) PL148535B1 (fi)
RU (1) RU1779251C (fi)
SE (1) SE467357B (fi)
YU (1) YU46223B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
US5639751A (en) * 1990-12-21 1997-06-17 Cyogyszerkutato Intezet Kft N-acyl-2,3-benzodiazepine derivatives for treating acute and chronic neurodegenerative disorders
HU206719B (en) * 1990-12-21 1992-12-28 Gyogyszerkutato Intezet Process for producing 1-/4-acylamino-phenyl/-7,8-methylenedioxy-5h-2,3-benzodiazepine derivatives, acid addicional salts and pharmaceutical compositions containing them
TR199501071A2 (tr) * 1994-08-31 1996-06-21 Lilly Co Eli Dihidro-2,3-benzodiazepin türevlerinin üretilmesi icin stereoselektif islem.
US6288057B1 (en) * 1994-08-31 2001-09-11 Eli Lilly And Company Physical form of dihydro-2,3-benzodiazepine derivative
US5891871A (en) * 1996-03-21 1999-04-06 Cocensys, Inc. Substituted 2,3-benzodiazepin-4-ones and the use thereof
UA67749C2 (uk) 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
US6649607B2 (en) * 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
US20040152695A1 (en) * 2002-12-03 2004-08-05 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine and uses thereof
CA2508542A1 (en) * 2002-12-03 2004-06-17 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5h-2,3-benzodiazepine and uses thereof
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20070021412A1 (en) * 2003-05-16 2007-01-25 Vela Pharmaceuticals, Inc. Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (S) 2,3-benzodiazepine
CA2525273C (en) * 2003-05-16 2012-04-17 Vela Pharmaceuticals, Inc. Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (r) 2,3-benzodiazepine
US20040254173A1 (en) * 2003-06-13 2004-12-16 Leventer Steven M. Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines
US20050096464A1 (en) * 2003-10-30 2005-05-05 Heikki Heikkila Separation process
EP4197536A1 (en) * 2021-12-20 2023-06-21 Universitat de València Haloperidol for use in the treatment of spinal muscular atrophy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU186760B (en) * 1981-03-12 1985-09-30 Gyogyszerkutato Intezet Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
DE3319491A1 (de) * 1982-06-19 1983-10-13 Alps Electric Co., Ltd., Tokyo Papierfuehrungsmechanismus fuer schreibgeraete
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines

Also Published As

Publication number Publication date
US4835152A (en) 1989-05-30
DK164555C (da) 1992-11-30
FI85706B (fi) 1992-02-14
NL8701909A (nl) 1988-03-01
DE3727226A1 (de) 1988-02-18
FI85706C (fi) 1992-05-25
RU1779251C (ru) 1992-11-30
FR2602773A1 (fr) 1988-02-19
DD265627A5 (de) 1989-03-08
HUT47287A (en) 1989-02-28
IT1222508B (it) 1990-09-05
FR2602773B1 (fr) 1990-11-02
DK164555B (da) 1992-07-13
NO873426D0 (no) 1987-08-14
CH673652A5 (fi) 1990-03-30
ATA202187A (de) 1993-06-15
BE1002415A4 (fr) 1991-02-05
NO164656C (no) 1990-10-31
YU46223B (sh) 1993-05-28
YU151487A (en) 1988-12-31
GB2194236A (en) 1988-03-02
ES2004985A6 (es) 1989-02-16
SE8703169L (sv) 1988-02-16
IT8721667A0 (it) 1987-08-14
CS600787A2 (en) 1988-08-16
NO873426L (no) 1988-02-16
FI873525A0 (fi) 1987-08-14
JPS6399073A (ja) 1988-04-30
HU198494B (en) 1989-10-30
DK424887D0 (da) 1987-08-14
CA1284322C (en) 1991-05-21
AU7688087A (en) 1988-02-18
GB8719265D0 (en) 1987-09-23
NO164656B (no) 1990-07-23
CS264150B2 (en) 1989-06-13
GB2194236B (en) 1990-03-21
SE467357B (sv) 1992-07-06
DK424887A (da) 1988-02-16
PL148535B1 (en) 1989-10-31
AU596206B2 (en) 1990-04-26
SE8703169D0 (sv) 1987-08-14

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Owner name: BIOGAL GYOGYSZERGYAR RT.