DE3772122D1 - Substituierte 1,5-benzodiazepin-derivate. - Google Patents

Substituierte 1,5-benzodiazepin-derivate.

Info

Publication number
DE3772122D1
DE3772122D1 DE8787109253T DE3772122T DE3772122D1 DE 3772122 D1 DE3772122 D1 DE 3772122D1 DE 8787109253 T DE8787109253 T DE 8787109253T DE 3772122 T DE3772122 T DE 3772122T DE 3772122 D1 DE3772122 D1 DE 3772122D1
Authority
DE
Germany
Prior art keywords
substituted
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787109253T
Other languages
English (en)
Inventor
Karnail Singh Atwal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of DE3772122D1 publication Critical patent/DE3772122D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DE8787109253T 1986-07-18 1987-06-26 Substituierte 1,5-benzodiazepin-derivate. Expired - Fee Related DE3772122D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/886,847 US4650797A (en) 1986-07-18 1986-07-18 Substituted 1,5-benzodiazepine compounds

Publications (1)

Publication Number Publication Date
DE3772122D1 true DE3772122D1 (de) 1991-09-19

Family

ID=25389908

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787109253T Expired - Fee Related DE3772122D1 (de) 1986-07-18 1987-06-26 Substituierte 1,5-benzodiazepin-derivate.

Country Status (4)

Country Link
US (1) US4650797A (de)
EP (1) EP0253178B1 (de)
JP (1) JPS6333369A (de)
DE (1) DE3772122D1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4650797A (en) * 1986-07-18 1987-03-17 E. R. Squibb & Sons, Inc. Substituted 1,5-benzodiazepine compounds
US4824831A (en) * 1987-12-21 1989-04-25 E. R. Squibb & Sons, Inc. 4,5-dihydro-1H-benzazepine-3-carboxylic acid esters which are useful as anti-hypertensive agents
US5580979A (en) * 1994-03-15 1996-12-03 Trustees Of Tufts University Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions
WO2003009815A2 (en) 2001-07-25 2003-02-06 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
JP4929500B2 (ja) * 2005-02-17 2012-05-09 塩野義製薬株式会社 新規ベンゾジアゼピン類
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
AU2010245823B2 (en) 2009-05-06 2016-11-24 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN105384700A (zh) * 2015-12-08 2016-03-09 梁彦云 一种治疗心肌损伤的药物组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4654335A (en) * 1985-07-11 1987-03-31 E. R. Squibb & Sons, Inc. Antihypertensive 1,5-benzothiazepine derivatives, compositions, and method of use therefor
US4647561A (en) * 1985-08-05 1987-03-03 E. R. Squibb & Sons, Inc. 1,5-benzodiazepine compounds
US4650797A (en) * 1986-07-18 1987-03-17 E. R. Squibb & Sons, Inc. Substituted 1,5-benzodiazepine compounds

Also Published As

Publication number Publication date
JPS6333369A (ja) 1988-02-13
EP0253178B1 (de) 1991-08-14
US4650797A (en) 1987-03-17
EP0253178A1 (de) 1988-01-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee