DE3874027D1 - 1,3-dithiol-2-yliden-derivate. - Google Patents

1,3-dithiol-2-yliden-derivate.

Info

Publication number
DE3874027D1
DE3874027D1 DE8888810444T DE3874027T DE3874027D1 DE 3874027 D1 DE3874027 D1 DE 3874027D1 DE 8888810444 T DE8888810444 T DE 8888810444T DE 3874027 T DE3874027 T DE 3874027T DE 3874027 D1 DE3874027 D1 DE 3874027D1
Authority
DE
Germany
Prior art keywords
yliden
dithiol
derivatives
yliden derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888810444T
Other languages
English (en)
Other versions
DE3874027T2 (de
Inventor
Sup Kim Choong Sup Kim Choong
Seok Chae Jeong Seok Cha Jeong
Wook Lee Jong Wook Lee Jong
Ro Choi Young Ro Choi Young
Keun Yoo Joung Keun Yoo Joung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yuhan Corp
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of DE3874027D1 publication Critical patent/DE3874027D1/de
Application granted granted Critical
Publication of DE3874027T2 publication Critical patent/DE3874027T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
DE8888810444T 1987-07-01 1988-06-27 1,3-dithiol-2-yliden-derivate. Expired - Fee Related DE3874027T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019870006745A KR910005895B1 (ko) 1987-07-01 1987-07-01 1,3-디티올-2-일리덴 유도체와 그의 제조방법

Publications (2)

Publication Number Publication Date
DE3874027D1 true DE3874027D1 (de) 1992-10-01
DE3874027T2 DE3874027T2 (de) 1993-02-11

Family

ID=19262499

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888810444T Expired - Fee Related DE3874027T2 (de) 1987-07-01 1988-06-27 1,3-dithiol-2-yliden-derivate.

Country Status (5)

Country Link
US (1) US5158950A (de)
EP (1) EP0298040B1 (de)
JP (1) JPH01104068A (de)
KR (1) KR910005895B1 (de)
DE (1) DE3874027T2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920005434B1 (ko) * 1988-10-27 1992-07-03 주식회사 유한양행 티오케텐 유도체와 그의 제조방법
JPH11124379A (ja) * 1997-10-17 1999-05-11 Ss Pharmaceut Co Ltd ジチオリリデンアセトアミド誘導体

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5028498B2 (de) * 1973-02-03 1975-09-16
ZA763077B (en) * 1975-06-06 1977-04-27 Nihon Nohyaku Co Ltd Pharmaceutical composition cor curing liver diseases
JPS5463085A (en) * 1977-10-28 1979-05-21 Nippon Nohyaku Co Ltd Preparation of malonic acid derivative
JPS5533471A (en) * 1979-07-30 1980-03-08 Nippon Nohyaku Co Ltd Preparation of 1,3-dithiol-2-ylidene-malonic ester
JPS6016956B2 (ja) * 1979-10-27 1985-04-30 日本農薬株式会社 １，３−ジチオ−ル−２−イリデンマロネ−トの製造方法
US4327223A (en) * 1981-04-07 1982-04-27 Nihon Nohyaku Co., Ltd. Process for producing 1,3-dithiol-2-ylidene malonates
US4329479A (en) * 1981-04-07 1982-05-11 Nihon Nohyaku Co., Ltd. Process for producing 1,3-dithiol-2-ylidene malonic acid dialkyl esters
JPS5942377A (ja) * 1982-09-01 1984-03-08 Nippon Nohyaku Co Ltd ジチオ−ル誘導体
GB8401010D0 (en) * 1984-01-14 1984-02-15 Tanabe Seiyaku Co Thioketene derivatives
US4663319A (en) * 1984-01-14 1987-05-05 Tanabe Seiysku Co., Ltd. 3-(1,3-dithiol-2-ylidene)-2,4-dioxopyrrolidines, -piperidines, and -hexahydroazepines and use thereof against hepatic diseases
JPS60215682A (ja) * 1984-04-11 1985-10-29 Banyu Pharmaceut Co Ltd １，３−ジチオ−ル−２−イリデン誘導体
US4668799A (en) * 1985-05-30 1987-05-26 Banyu Pharmaceutical Co., Ltd. Anti-hepatitis and anti-cirrhotic 1,3-dithiol-2-ylidene derivatives, and pharmaceutical compositions therefor
DE3586541T2 (de) * 1985-05-31 1993-01-14 Banyu Pharma Co Ltd 1,3-dithiol-2-ylidenderivate.
JPS62158274A (ja) * 1985-12-28 1987-07-14 Banyu Pharmaceut Co Ltd 置換−１，３−ジチエタン誘導体
JPS632988A (ja) * 1986-03-19 1988-01-07 Hokko Chem Ind Co Ltd １，３−ジチオ−ル−２−イリデン　スルホニル酢酸誘導体

Also Published As

Publication number Publication date
KR890002092A (ko) 1989-04-08
JPH01104068A (ja) 1989-04-21
US5158950A (en) 1992-10-27
EP0298040B1 (de) 1992-08-26
DE3874027T2 (de) 1993-02-11
EP0298040A1 (de) 1989-01-04
KR910005895B1 (ko) 1991-08-06
JPH0587070B2 (de) 1993-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee