NO812557L - Fremgangsmaate for fremstilling av terapeutisk aktive 9-amino-1-hydroksyoktahydrobenzo(c)kinolinderivater - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive 9-amino-1-hydroksyoktahydrobenzo(c)kinolinderivater

Info

Publication number
NO812557L
NO812557L NO812557A NO812557A NO812557L NO 812557 L NO812557 L NO 812557L NO 812557 A NO812557 A NO 812557A NO 812557 A NO812557 A NO 812557A NO 812557 L NO812557 L NO 812557L
Authority
NO
Norway
Prior art keywords
hydrogen
formula
methyl
carbon atoms
compound
Prior art date
Application number
NO812557A
Other languages
English (en)
Norwegian (no)
Inventor
Michael Ross Johnson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO812557L publication Critical patent/NO812557L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NO812557A 1980-07-28 1981-07-27 Fremgangsmaate for fremstilling av terapeutisk aktive 9-amino-1-hydroksyoktahydrobenzo(c)kinolinderivater NO812557L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/173,207 US4309545A (en) 1980-07-28 1980-07-28 Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof

Publications (1)

Publication Number Publication Date
NO812557L true NO812557L (no) 1982-01-29

Family

ID=22630983

Family Applications (2)

Application Number Title Priority Date Filing Date
NO812557A NO812557L (no) 1980-07-28 1981-07-27 Fremgangsmaate for fremstilling av terapeutisk aktive 9-amino-1-hydroksyoktahydrobenzo(c)kinolinderivater
NO854454A NO854454L (no) 1980-07-28 1985-11-08 1-hydroksy-5,6,6a-beta,7-tertahydrobenzo(c)-kinolin-9(8h)-oksim-derivater.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO854454A NO854454L (no) 1980-07-28 1985-11-08 1-hydroksy-5,6,6a-beta,7-tertahydrobenzo(c)-kinolin-9(8h)-oksim-derivater.

Country Status (29)

Country Link
US (1) US4309545A (en:Method)
EP (1) EP0045171B1 (en:Method)
JP (1) JPS57112372A (en:Method)
KR (1) KR850000273B1 (en:Method)
AR (1) AR230988A1 (en:Method)
AT (1) ATE11775T1 (en:Method)
AU (1) AU525944B2 (en:Method)
CA (1) CA1178274A (en:Method)
CS (1) CS228515B2 (en:Method)
DD (1) DD202012A5 (en:Method)
DE (1) DE3168891D1 (en:Method)
DK (1) DK334581A (en:Method)
EG (1) EG15535A (en:Method)
ES (1) ES8301926A1 (en:Method)
FI (1) FI812338A7 (en:Method)
GR (1) GR75283B (en:Method)
GT (1) GT198170557A (en:Method)
HU (1) HU185133B (en:Method)
IE (1) IE51426B1 (en:Method)
IL (1) IL63423A0 (en:Method)
IN (1) IN158867B (en:Method)
NO (2) NO812557L (en:Method)
NZ (1) NZ197856A (en:Method)
PH (1) PH17281A (en:Method)
PL (1) PL133928B1 (en:Method)
PT (1) PT73440B (en:Method)
SU (1) SU1217254A3 (en:Method)
YU (1) YU185181A (en:Method)
ZA (1) ZA815128B (en:Method)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920221A (en) * 1982-03-16 1990-04-24 Pfizer Inc. Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US5605906A (en) * 1995-03-24 1997-02-25 Merck Frosst Canada, Inc. Cannabinoid receptor agonists
EE03523B1 (et) * 1996-01-31 2001-10-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Fenantridiinid, neid sisaldavad ravimid ja nende kasutamine
ATE224386T1 (de) * 1996-03-26 2002-10-15 Altana Pharma Ag Neue in 6-position substituierte phenanthridine
US6127378A (en) * 1996-03-26 2000-10-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenanthridines substituted in the 6 position
US5776482A (en) * 1996-03-29 1998-07-07 University Of Iowa Research Foundation Tetrahydroquinoline analogues for use in glaucoma treatment
PT1000035E (pt) * 1997-07-25 2003-04-30 Altana Pharma Ag 6-fenilfenantridinas substituidas
ATE224372T1 (de) * 1997-07-25 2002-10-15 Altana Pharma Ag Substituierte 6-alkylphenanthridine
BR0009200A (pt) 1999-03-22 2001-12-26 Immugen Pharmaceuticals Inc Compostos e composições para o tratamento dedoenças associada com disfunção imune
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US20060084021A1 (en) * 2004-09-10 2006-04-20 Kubicek Chris A Wick holder
AU2001296402A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
AU2002213429A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
AU2003214226A1 (en) * 2002-03-18 2003-10-08 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
NZ551379A (en) * 2004-05-25 2010-11-26 Othera Holding Inc Oculoselective drugs and prodrugs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839441A (en) * 1969-10-27 1974-10-01 Hoffmann La Roche Intermediates for partially hydrogenated phenanthridines
US3878219A (en) * 1973-07-13 1975-04-15 Abbott Lab 5H-{8 1{9 benzopyrano{8 3,4-d{9 pyridines
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
HU180916B (hu) 1976-05-17 1983-05-30 Pfizer Eljárás benzo[c]kinolin-származékok előállítására
US4152450A (en) * 1978-02-17 1979-05-01 Eli Lilly And Company 9-Amino-dibenzopyrans

Also Published As

Publication number Publication date
AU525944B2 (en) 1982-12-09
PL232331A1 (en) 1983-09-26
US4309545A (en) 1982-01-05
FI812338L (fi) 1982-01-29
ES504323A0 (es) 1982-12-16
GT198170557A (es) 1983-01-12
HU185133B (en) 1984-12-28
IL63423A0 (en) 1981-10-30
EP0045171A2 (en) 1982-02-03
PL133928B1 (en) 1985-07-31
ZA815128B (en) 1982-07-28
AR230988A1 (es) 1984-08-31
PT73440A (en) 1981-08-01
PT73440B (en) 1983-06-20
IE51426B1 (en) 1986-12-24
KR850000273B1 (ko) 1985-03-15
DE3168891D1 (en) 1985-03-28
GR75283B (en:Method) 1984-07-13
EG15535A (en) 1986-09-30
JPS57112372A (en) 1982-07-13
ATE11775T1 (de) 1985-02-15
NO854454L (no) 1985-01-29
YU185181A (en) 1983-12-31
NZ197856A (en) 1984-10-19
CS228515B2 (en) 1984-05-14
DK334581A (da) 1982-01-29
ES8301926A1 (es) 1982-12-16
SU1217254A3 (ru) 1986-03-07
DD202012A5 (de) 1983-08-24
EP0045171B1 (en) 1985-02-13
CA1178274A (en) 1984-11-20
FI812338A7 (fi) 1982-01-29
IN158867B (en:Method) 1987-02-07
AU7343481A (en) 1982-05-06
PH17281A (en) 1984-07-06
EP0045171A3 (en) 1982-04-28
KR830006217A (ko) 1983-09-20
IE811686L (en) 1982-01-28

Similar Documents

Publication Publication Date Title
NO812557L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 9-amino-1-hydroksyoktahydrobenzo(c)kinolinderivater
NL192451C (nl) Werkwijze voor de bereiding van ftalanderivaten en werkwijze voor de bereiding van farmaceutische preparaten die een ftalanderivaat bevatten.
US4260764A (en) 9-Hydroxyoctahydrobenzo [C] quinolines and intermediates therefor
JPS63277671A (ja) ３−アミノ−ジヒドロ−〔１〕−ベンゾピランおよびベンゾチオピラン
CN103073559B (zh) 手性芳香螺缩酮类化合物及其制备方法和应用
FI76334B (fi) Foerfarande foer framstaellning av som analgetiska och antiemetiska medel anvaendbara hexahydropyrrolo/1,2-a/ kinolin- och hexahydro-1h-pyrido/1,2-a/kinolinderivat.
NO147028B (no) Analogifremgangsmaate for fremstilling av farmasoeytisk aktive 1-hydroksyoktahydrobenzo(c)kinoliner
NO803693L (no) 2,3-indoldion-derivater.
US4351833A (en) 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
DD211559A5 (de) Verfahren zur herstellung bicyclischer, benzokondensierter verbindungen
HU180916B (hu) Eljárás benzo[c]kinolin-származékok előállítására
US4405626A (en) 9-Hydroxyoctahydrobenzo(c)quinolines analgesic compositions containing them and processes for producing analgesic with them
US4340737A (en) 9-Hydroxyoctahydrobenzo[C]quinolines and intermediates therefor
US3442949A (en) Method for preparing 5-(3-aminopropylidene)-5h-dibenzo - (a,d) - 10,11 - dihydrocycloheptenes
WO1990012795A1 (en) Substituted 3-amino chromans
US3583997A (en) Benzothiopyrano(2,3-c)pyridines
NO143169B (no) Veggkonsoll til feste av forhaandsmonterte markisebeslag
FI64142B (fi) Foerfarande foer framstaellning av nya terapeutiskt aktiva benso(c)kinolinonderivat
CA1101860A (en) Tetrahydro benzo [c] quinoline 9 (8h) ones useful as intermediates in the productions of pharmaceuticals
US4400385A (en) 9-Hydroxyoctahydrobenzo [c]quinolines, analgesic compositions containing them and processes for producing analgesia with them
US4380542A (en) 9-Hydroxyoctahydrobenzo[c]quinolines and their pharmaceutical compositions and method of use
KR820001354B1 (ko) 벤조[c]퀴놀린의 제조방법
US3884967A (en) Tricyclic amines and processes for the preparation thereof
KR820001353B1 (ko) 벤조[c〕 퀴놀린의 제조방법
US3960974A (en) 4-Halo-2,3,5,6-dibenzobicyclo[5.1.0]octane