NO812344L - Analogifremgangsmaate for fremstilling av terapeutisk aktive steroider. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive steroider.

Info

Publication number
NO812344L
NO812344L NO812344A NO812344A NO812344L NO 812344 L NO812344 L NO 812344L NO 812344 A NO812344 A NO 812344A NO 812344 A NO812344 A NO 812344A NO 812344 L NO812344 L NO 812344L
Authority
NO
Norway
Prior art keywords
preparation
therapeutic active
active steroids
analogue procedure
analogue
Prior art date
Application number
NO812344A
Other languages
English (en)
Other versions
NO163285B (no
NO163285C (no
Inventor
Nicholas Stephen Bodor
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO812344L publication Critical patent/NO812344L/no
Publication of NO163285B publication Critical patent/NO163285B/no
Publication of NO163285C publication Critical patent/NO163285C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO812344A 1980-07-10 1981-07-09 Analogifremgangsmaate for fremstilling av terapeutisk aktive steroider. NO163285C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16845380A 1980-07-10 1980-07-10
US26578581A 1981-05-21 1981-05-21

Publications (3)

Publication Number Publication Date
NO812344L true NO812344L (no) 1982-01-11
NO163285B NO163285B (no) 1990-01-22
NO163285C NO163285C (no) 1990-05-02

Family

ID=26864131

Family Applications (1)

Application Number Title Priority Date Filing Date
NO812344A NO163285C (no) 1980-07-10 1981-07-09 Analogifremgangsmaate for fremstilling av terapeutisk aktive steroider.

Country Status (17)

Country Link
KR (2) KR860000266B1 (no)
AT (1) AT379816B (no)
AU (1) AU540898B2 (no)
CA (1) CA1174667A (no)
CH (1) CH648856A5 (no)
DE (1) DE3126732C2 (no)
DK (1) DK165837C (no)
ES (2) ES8300785A1 (no)
FI (1) FI71748C (no)
FR (1) FR2486529A1 (no)
GB (1) GB2079755B (no)
IT (1) IT1205446B (no)
NL (1) NL192343C (no)
NO (1) NO163285C (no)
PH (1) PH25874A (no)
PT (1) PT73348B (no)
SE (1) SE449106B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2137206B (en) * 1980-02-15 1985-04-03 Glaxo Group Ltd Androstane 17-carbothioc acid derivatives
JPS6041607A (ja) * 1983-08-12 1985-03-05 Otsuka Pharmaceut Co Ltd 軟膏基剤
SE8501693D0 (sv) * 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
IL78144A0 (en) * 1985-04-04 1986-07-31 Draco Ab Novel androstane-17beta-carboxylic acid esters
DE3786174T2 (de) * 1987-10-13 1993-10-21 Nicholas S Bodor Weiche steroide mit anti-entzündungswirkung.
DE4025342A1 (de) * 1990-08-10 1992-02-13 Hoechst Ag In 17-stellung substituierte corticoid-17-alkylcarbonate, verfahren zu deren herstellung und diese enthaltende arzneimittel
JP2000513380A (ja) * 1997-06-30 2000-10-10 グラクソ、グループ、リミテッド 化合物
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6750210B2 (en) 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US6858593B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6777400B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
ES2292604T5 (es) 2000-08-05 2015-06-01 Glaxo Group Limited Éster S-fluorometílico del ácido 6 ,9 -difluoro-17 -[(2-furanilcarbonil)oxi]-11 -hidroxi-16 -metil-3-oxo-androsta-1,4-dien-17 -carbotioico como agente antiinflamatorio
US6787532B2 (en) 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
GB0316290D0 (en) * 2003-07-11 2003-08-13 Glaxo Group Ltd Novel compounds
US7579335B2 (en) 2005-01-10 2009-08-25 Glaxo Group Limited Androstane 17α-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
AR059216A1 (es) * 2006-01-27 2008-03-19 Sun Pharmaceutical Ind Ltd 11b-hidroxiandrosta-4-eno-3-onas
US7687484B2 (en) * 2006-05-25 2010-03-30 Bodor Nicholas S Transporter enhanced corticosteroid activity
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
CN101942001B (zh) * 2010-08-24 2013-02-06 山东省医药工业研究所 一种氯替泼诺的提纯方法
CN103183714A (zh) * 2011-12-29 2013-07-03 山东方明药业集团股份有限公司 一种氯替泼诺的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1384372A (en) * 1971-01-20 1975-02-19 Glaxo Lab Ltd Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
IT1114534B (it) * 1978-02-08 1986-01-27 Glaxo Group Ltd Steroide anti-infiammatorio della serie dell'androstano composizioni che lo contengono e procedimento per produrlo
US4188385A (en) * 1978-04-05 1980-02-12 Syntex (U.S.A.) Inc. Thioetianic acid derivatives
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung

Also Published As

Publication number Publication date
GB2079755B (en) 1985-01-30
ATA307081A (de) 1985-07-15
ES504340A0 (es) 1982-12-01
FI812175L (fi) 1982-01-11
ES8300785A1 (es) 1982-12-01
FI71748C (fi) 1987-02-09
PT73348B (en) 1982-09-23
NO163285B (no) 1990-01-22
DK165837C (da) 1993-06-21
ES514633A0 (es) 1983-06-16
NL8103315A (nl) 1982-02-01
KR830006327A (ko) 1983-09-24
IT8105186A0 (it) 1981-07-09
CH648856A5 (de) 1985-04-15
DE3126732A1 (de) 1982-03-25
KR860000266B1 (ko) 1986-03-22
AT379816B (de) 1986-03-10
AU540898B2 (en) 1984-12-06
AU7259181A (en) 1982-01-14
GB2079755A (en) 1982-01-27
SE8104132L (sv) 1982-01-11
DK165837B (da) 1993-01-25
NL192343B (nl) 1997-02-03
PT73348A (en) 1981-08-01
FI71748B (fi) 1986-10-31
FR2486529A1 (fr) 1982-01-15
KR860000452B1 (ko) 1986-04-26
PH25874A (en) 1991-12-02
CA1174667A (en) 1984-09-18
ES8306767A1 (es) 1983-06-16
DE3126732C2 (de) 1987-04-30
IT1205446B (it) 1989-03-23
FR2486529B1 (no) 1985-01-04
NO163285C (no) 1990-05-02
KR850002759A (ko) 1985-05-15
SE449106B (sv) 1987-04-06
DK302181A (da) 1982-01-11
NL192343C (nl) 1997-06-04

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