ES514633A0 - "metodo de preparar compuestos esteroidicos antiinflamatorios". - Google Patents

"metodo de preparar compuestos esteroidicos antiinflamatorios".

Info

Publication number
ES514633A0
ES514633A0 ES514633A ES514633A ES514633A0 ES 514633 A0 ES514633 A0 ES 514633A0 ES 514633 A ES514633 A ES 514633A ES 514633 A ES514633 A ES 514633A ES 514633 A0 ES514633 A0 ES 514633A0
Authority
ES
Spain
Prior art keywords
preparing anti
steroid compounds
inflammatory steroid
inflammatory
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES514633A
Other languages
English (en)
Other versions
ES8306767A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of ES514633A0 publication Critical patent/ES514633A0/es
Publication of ES8306767A1 publication Critical patent/ES8306767A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES514633A 1980-07-10 1982-08-02 "metodo de preparar compuestos esteroidicos antiinflamatorios". Expired ES8306767A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16845380A 1980-07-10 1980-07-10
US26578581A 1981-05-21 1981-05-21

Publications (2)

Publication Number Publication Date
ES514633A0 true ES514633A0 (es) 1983-06-16
ES8306767A1 ES8306767A1 (es) 1983-06-16

Family

ID=26864131

Family Applications (2)

Application Number Title Priority Date Filing Date
ES504340A Expired ES8300785A1 (es) 1980-07-10 1981-07-10 Procedimiento de preparar esteroides e intermedios de este- roides antiinflamatorios
ES514633A Expired ES8306767A1 (es) 1980-07-10 1982-08-02 "metodo de preparar compuestos esteroidicos antiinflamatorios".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES504340A Expired ES8300785A1 (es) 1980-07-10 1981-07-10 Procedimiento de preparar esteroides e intermedios de este- roides antiinflamatorios

Country Status (17)

Country Link
KR (2) KR860000266B1 (es)
AT (1) AT379816B (es)
AU (1) AU540898B2 (es)
CA (1) CA1174667A (es)
CH (1) CH648856A5 (es)
DE (1) DE3126732C2 (es)
DK (1) DK165837C (es)
ES (2) ES8300785A1 (es)
FI (1) FI71748C (es)
FR (1) FR2486529A1 (es)
GB (1) GB2079755B (es)
IT (1) IT1205446B (es)
NL (1) NL192343C (es)
NO (1) NO163285C (es)
PH (1) PH25874A (es)
PT (1) PT73348B (es)
SE (1) SE449106B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2137206B (en) * 1980-02-15 1985-04-03 Glaxo Group Ltd Androstane 17-carbothioc acid derivatives
JPS6041607A (ja) * 1983-08-12 1985-03-05 Otsuka Pharmaceut Co Ltd 軟膏基剤
SE8501693D0 (sv) * 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
IL78144A0 (en) * 1985-04-04 1986-07-31 Draco Ab Novel androstane-17beta-carboxylic acid esters
DE3786174T2 (de) * 1987-10-13 1993-10-21 Nicholas S Bodor Weiche steroide mit anti-entzündungswirkung.
DE4025342A1 (de) * 1990-08-10 1992-02-13 Hoechst Ag In 17-stellung substituierte corticoid-17-alkylcarbonate, verfahren zu deren herstellung und diese enthaltende arzneimittel
JP2000513380A (ja) * 1997-06-30 2000-10-10 グラクソ、グループ、リミテッド 化合物
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6750210B2 (en) 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US6858593B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6777400B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
ES2292604T5 (es) 2000-08-05 2015-06-01 Glaxo Group Limited Éster S-fluorometílico del ácido 6 ,9 -difluoro-17 -[(2-furanilcarbonil)oxi]-11 -hidroxi-16 -metil-3-oxo-androsta-1,4-dien-17 -carbotioico como agente antiinflamatorio
US6787532B2 (en) 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
GB0316290D0 (en) * 2003-07-11 2003-08-13 Glaxo Group Ltd Novel compounds
US7579335B2 (en) 2005-01-10 2009-08-25 Glaxo Group Limited Androstane 17α-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
AR059216A1 (es) * 2006-01-27 2008-03-19 Sun Pharmaceutical Ind Ltd 11b-hidroxiandrosta-4-eno-3-onas
US7687484B2 (en) * 2006-05-25 2010-03-30 Bodor Nicholas S Transporter enhanced corticosteroid activity
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
CN101942001B (zh) * 2010-08-24 2013-02-06 山东省医药工业研究所 一种氯替泼诺的提纯方法
CN103183714A (zh) * 2011-12-29 2013-07-03 山东方明药业集团股份有限公司 一种氯替泼诺的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1384372A (en) * 1971-01-20 1975-02-19 Glaxo Lab Ltd Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
IT1114534B (it) * 1978-02-08 1986-01-27 Glaxo Group Ltd Steroide anti-infiammatorio della serie dell'androstano composizioni che lo contengono e procedimento per produrlo
US4188385A (en) * 1978-04-05 1980-02-12 Syntex (U.S.A.) Inc. Thioetianic acid derivatives
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung

Also Published As

Publication number Publication date
GB2079755B (en) 1985-01-30
ATA307081A (de) 1985-07-15
ES504340A0 (es) 1982-12-01
FI812175L (fi) 1982-01-11
ES8300785A1 (es) 1982-12-01
FI71748C (fi) 1987-02-09
PT73348B (en) 1982-09-23
NO163285B (no) 1990-01-22
DK165837C (da) 1993-06-21
NL8103315A (nl) 1982-02-01
KR830006327A (ko) 1983-09-24
IT8105186A0 (it) 1981-07-09
CH648856A5 (de) 1985-04-15
DE3126732A1 (de) 1982-03-25
KR860000266B1 (ko) 1986-03-22
AT379816B (de) 1986-03-10
AU540898B2 (en) 1984-12-06
AU7259181A (en) 1982-01-14
GB2079755A (en) 1982-01-27
SE8104132L (sv) 1982-01-11
DK165837B (da) 1993-01-25
NL192343B (nl) 1997-02-03
PT73348A (en) 1981-08-01
FI71748B (fi) 1986-10-31
FR2486529A1 (fr) 1982-01-15
KR860000452B1 (ko) 1986-04-26
PH25874A (en) 1991-12-02
NO812344L (no) 1982-01-11
CA1174667A (en) 1984-09-18
ES8306767A1 (es) 1983-06-16
DE3126732C2 (de) 1987-04-30
IT1205446B (it) 1989-03-23
FR2486529B1 (es) 1985-01-04
NO163285C (no) 1990-05-02
KR850002759A (ko) 1985-05-15
SE449106B (sv) 1987-04-06
DK302181A (da) 1982-01-11
NL192343C (nl) 1997-06-04

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20030211