IT8105186A0 - Steroidi metabolizzabili o degradabili capaci di esplicare un'azione antiflogistica. - Google Patents

Steroidi metabolizzabili o degradabili capaci di esplicare un'azione antiflogistica.

Info

Publication number
IT8105186A0
IT8105186A0 IT8105186A IT518681A IT8105186A0 IT 8105186 A0 IT8105186 A0 IT 8105186A0 IT 8105186 A IT8105186 A IT 8105186A IT 518681 A IT518681 A IT 518681A IT 8105186 A0 IT8105186 A0 IT 8105186A0
Authority
IT
Italy
Prior art keywords
explaing
metabolisable
degradable
steroids
phlogistic
Prior art date
Application number
IT8105186A
Other languages
English (en)
Other versions
IT1205446B (it
Inventor
Nicholas Stephen Bodor
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of IT8105186A0 publication Critical patent/IT8105186A0/it
Application granted granted Critical
Publication of IT1205446B publication Critical patent/IT1205446B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT05186/81A 1980-07-10 1981-07-09 Stereoidi metabolizzabili o degradabili capaci di esplicare un'azione antiflogistica IT1205446B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16845380A 1980-07-10 1980-07-10
US26578581A 1981-05-21 1981-05-21

Publications (2)

Publication Number Publication Date
IT8105186A0 true IT8105186A0 (it) 1981-07-09
IT1205446B IT1205446B (it) 1989-03-23

Family

ID=26864131

Family Applications (1)

Application Number Title Priority Date Filing Date
IT05186/81A IT1205446B (it) 1980-07-10 1981-07-09 Stereoidi metabolizzabili o degradabili capaci di esplicare un'azione antiflogistica

Country Status (17)

Country Link
KR (2) KR860000266B1 (it)
AT (1) AT379816B (it)
AU (1) AU540898B2 (it)
CA (1) CA1174667A (it)
CH (1) CH648856A5 (it)
DE (1) DE3126732A1 (it)
DK (1) DK165837C (it)
ES (2) ES8300785A1 (it)
FI (1) FI71748C (it)
FR (1) FR2486529A1 (it)
GB (1) GB2079755B (it)
IT (1) IT1205446B (it)
NL (1) NL192343C (it)
NO (1) NO163285C (it)
PH (1) PH25874A (it)
PT (1) PT73348B (it)
SE (1) SE449106B (it)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2137206B (en) * 1980-02-15 1985-04-03 Glaxo Group Ltd Androstane 17-carbothioc acid derivatives
JPS6041607A (ja) * 1983-08-12 1985-03-05 Otsuka Pharmaceut Co Ltd 軟膏基剤
SE8501693D0 (sv) * 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
IL78144A0 (en) * 1985-04-04 1986-07-31 Draco Ab Novel androstane-17beta-carboxylic acid esters
WO1989003390A1 (en) * 1987-10-13 1989-04-20 Bodor Nicholas S Soft steroids having anti-inflammatory activity
DE4025342A1 (de) * 1990-08-10 1992-02-13 Hoechst Ag In 17-stellung substituierte corticoid-17-alkylcarbonate, verfahren zu deren herstellung und diese enthaltende arzneimittel
ATE260931T1 (de) * 1997-06-30 2004-03-15 Glaxo Group Ltd Verfahren zur identifizierung von verbindungen mit verminderter systemischer aktivität
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
WO2002012265A1 (en) 2000-08-05 2002-02-14 Glaxo Group Limited 6.ALPHA., 9.ALPHA.-DIFLUORO-17.ALPHA.-`(2-FURANYLCARBOXYL) OXY!-11.BETA.-HYDROXY-16.ALPHA.-METHYL-3-OXO-ANDROST-1,4,-DIENE-17-CARBOTHIOIC ACID S-FLUOROMETHYL ESTER AS AN ANTI-INFLAMMATORY AGENT
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6750210B2 (en) 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US6777400B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6787532B2 (en) 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6858593B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
GB0316290D0 (en) * 2003-07-11 2003-08-13 Glaxo Group Ltd Novel compounds
ATE517908T1 (de) 2005-01-10 2011-08-15 Glaxo Group Ltd Androstan-17-alpha-carbonat-derivate zur verwendung bei der behandlung allergischer und entzündlicher zustände
TWI374147B (en) * 2006-01-27 2012-10-11 Sun Pharma Advance Res Company Ltd Novel 11β-hydroxyandrosta-4-ene-3-ones
US7687484B2 (en) * 2006-05-25 2010-03-30 Bodor Nicholas S Transporter enhanced corticosteroid activity
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
CN101942001B (zh) * 2010-08-24 2013-02-06 山东省医药工业研究所 一种氯替泼诺的提纯方法
CN103183714A (zh) * 2011-12-29 2013-07-03 山东方明药业集团股份有限公司 一种氯替泼诺的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1384372A (en) * 1971-01-20 1975-02-19 Glaxo Lab Ltd Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
IT1114534B (it) * 1978-02-08 1986-01-27 Glaxo Group Ltd Steroide anti-infiammatorio della serie dell'androstano composizioni che lo contengono e procedimento per produrlo
US4188385A (en) * 1978-04-05 1980-02-12 Syntex (U.S.A.) Inc. Thioetianic acid derivatives
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung

Also Published As

Publication number Publication date
CA1174667A (en) 1984-09-18
CH648856A5 (de) 1985-04-15
AT379816B (de) 1986-03-10
AU540898B2 (en) 1984-12-06
NL8103315A (nl) 1982-02-01
DE3126732C2 (it) 1987-04-30
SE449106B (sv) 1987-04-06
ES504340A0 (es) 1982-12-01
ES8306767A1 (es) 1983-06-16
DK165837C (da) 1993-06-21
FI71748C (fi) 1987-02-09
SE8104132L (sv) 1982-01-11
ATA307081A (de) 1985-07-15
FR2486529B1 (it) 1985-01-04
DK302181A (da) 1982-01-11
GB2079755B (en) 1985-01-30
ES514633A0 (es) 1983-06-16
NL192343C (nl) 1997-06-04
NL192343B (nl) 1997-02-03
GB2079755A (en) 1982-01-27
IT1205446B (it) 1989-03-23
FI71748B (fi) 1986-10-31
NO163285C (no) 1990-05-02
ES8300785A1 (es) 1982-12-01
KR860000452B1 (ko) 1986-04-26
PH25874A (en) 1991-12-02
NO163285B (no) 1990-01-22
NO812344L (no) 1982-01-11
KR830006327A (ko) 1983-09-24
FI812175L (fi) 1982-01-11
FR2486529A1 (fr) 1982-01-15
DE3126732A1 (de) 1982-03-25
KR850002759A (ko) 1985-05-15
KR860000266B1 (ko) 1986-03-22
PT73348B (en) 1982-09-23
DK165837B (da) 1993-01-25
AU7259181A (en) 1982-01-14
PT73348A (en) 1981-08-01

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970730