ES522823A0 - Derivados de 6 -metilprednisolona. - Google Patents
Derivados de 6 -metilprednisolona.Info
- Publication number
- ES522823A0 ES522823A0 ES522823A ES522823A ES522823A0 ES 522823 A0 ES522823 A0 ES 522823A0 ES 522823 A ES522823 A ES 522823A ES 522823 A ES522823 A ES 522823A ES 522823 A0 ES522823 A0 ES 522823A0
- Authority
- ES
- Spain
- Prior art keywords
- methylprednisolone
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9138982A JPS58208299A (ja) | 1982-05-31 | 1982-05-31 | 6α−メチルプレドニゾロン17,21−ジエステル化合物 |
JP11401182A JPS597200A (ja) | 1982-07-02 | 1982-07-02 | 6α−メチルプレドニゾロン17α−エステル化合物 |
JP6687283A JPS59193900A (ja) | 1983-04-15 | 1983-04-15 | 新規6α−メチルプレドニゾロン17α−エステル誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES522823A0 true ES522823A0 (es) | 1984-08-16 |
ES8407066A1 ES8407066A1 (es) | 1984-08-16 |
Family
ID=27299285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES522823A Expired ES8407066A1 (es) | 1982-05-31 | 1983-05-30 | Derivados de 6 -metilprednisolona. |
Country Status (3)
Country | Link |
---|---|
US (1) | US4567172A (es) |
EP (1) | EP0095894A3 (es) |
ES (1) | ES8407066A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3133081A1 (de) * | 1981-08-18 | 1983-03-10 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue 6(alpha)-methylprednisolon-derivate, ihre herstellung und verwendung |
DE3344834A1 (de) * | 1983-12-08 | 1985-06-13 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue hydrocortison-und prednisolon-derivate |
IT1199619B (it) * | 1985-01-03 | 1988-12-30 | Oece Ind Chimiche Spa | Vernici additivate |
DE4333920A1 (de) | 1993-10-05 | 1995-04-13 | Hoechst Ag | Corticoid-17,21-dicarbonsäureester sowie Corticosteroid-17-carbonsäureester-21-kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
GB9622884D0 (en) * | 1996-11-02 | 1997-01-08 | Duramed Europ Ltd | A method for th e preparation of steroids in the pregene class |
CN1978457B (zh) * | 2005-12-05 | 2010-06-09 | 浙江大学 | 6α-甲基强的松龙及其衍生物的生产方法 |
CN100439388C (zh) * | 2006-10-11 | 2008-12-03 | 汪家振 | 甲基泼尼松龙醋丙酸酯的合成方法 |
CN101659689B (zh) * | 2008-08-25 | 2013-07-03 | 天津金耀集团有限公司 | 一种甲泼尼龙衍生物 |
JP2012528140A (ja) * | 2009-05-29 | 2012-11-12 | ファイザー・リミテッド | 新規なグルココルチコイド受容体アゴニスト |
WO2011130877A1 (zh) * | 2010-04-21 | 2011-10-27 | 天津金耀集团有限公司 | 醋丙甲泼尼龙一水合物晶型及其制备方法 |
CN103193845B (zh) * | 2013-04-19 | 2015-07-08 | 中国科学院上海有机化学研究所 | 17羟基酰基化的皮质激素甾体药物中间体的合成方法 |
CN107840865A (zh) * | 2016-09-20 | 2018-03-27 | 天津金耀集团有限公司 | 一种甲泼尼龙的制备方法 |
CN111748010B (zh) * | 2019-03-29 | 2023-12-08 | 天津药业研究院股份有限公司 | 一种醋丙甲泼尼龙无水晶型及其组合物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1047518A (en) * | 1963-06-11 | 1966-11-02 | Glaxo Lab Ltd | 17ª-monoesters of 11,17,21-trihydroxy steroid compounds |
DE2144405A1 (de) * | 1971-09-04 | 1973-03-08 | Merck Patent Gmbh | Verfahren zur herstellung von estern der pregnanreihe |
DE3068965D1 (en) * | 1979-11-16 | 1984-09-20 | Sterosynt Ltd | 6-alpha-fluoro-16-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them |
JPS5686119A (en) * | 1979-12-17 | 1981-07-13 | Taiho Yakuhin Kogyo Kk | Steroid anti-inflammatory |
US4343799A (en) * | 1981-03-20 | 1982-08-10 | The Upjohn Company | Use of derivatives of 6α-methylprednisolone for the prevention or reduction of adriamycin-induced cardiotoxicity |
IL66432A0 (en) * | 1981-08-04 | 1982-12-31 | Plurichemie Anstalt | Process for the preparation of steroidal esters |
DE3133081A1 (de) * | 1981-08-18 | 1983-03-10 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue 6(alpha)-methylprednisolon-derivate, ihre herstellung und verwendung |
DE3133082A1 (de) * | 1981-08-18 | 1983-03-10 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue hydrocortison-derivate, ihre herstellung und verwendung |
-
1983
- 1983-05-25 EP EP83303027A patent/EP0095894A3/en not_active Ceased
- 1983-05-27 US US06/498,636 patent/US4567172A/en not_active Expired - Fee Related
- 1983-05-30 ES ES522823A patent/ES8407066A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0095894A3 (en) | 1985-01-02 |
ES8407066A1 (es) | 1984-08-16 |
US4567172A (en) | 1986-01-28 |
EP0095894A2 (en) | 1983-12-07 |
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