IT8322230A0 - Carbapenem-derivati fluoroalchilati. - Google Patents

Carbapenem-derivati fluoroalchilati.

Info

Publication number
IT8322230A0
IT8322230A0 IT8322230A IT2223083A IT8322230A0 IT 8322230 A0 IT8322230 A0 IT 8322230A0 IT 8322230 A IT8322230 A IT 8322230A IT 2223083 A IT2223083 A IT 2223083A IT 8322230 A0 IT8322230 A0 IT 8322230A0
Authority
IT
Italy
Prior art keywords
carbapenem
fluoroalkylated
derivatives
fluoroalkylated derivatives
Prior art date
Application number
IT8322230A
Other languages
English (en)
Other versions
IT8322230A1 (it
IT1194339B (it
Inventor
Ching Pong Mak
Hans Fliri
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8322230A0 publication Critical patent/IT8322230A0/it
Publication of IT8322230A1 publication Critical patent/IT8322230A1/it
Application granted granted Critical
Publication of IT1194339B publication Critical patent/IT1194339B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT22230/83A 1982-07-26 1983-07-26 Carbapenem-derivati fluoroalchilati IT1194339B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH453982 1982-07-26
CH565482 1982-09-24
CH764882 1982-12-31

Publications (3)

Publication Number Publication Date
IT8322230A0 true IT8322230A0 (it) 1983-07-26
IT8322230A1 IT8322230A1 (it) 1985-01-26
IT1194339B IT1194339B (it) 1988-09-14

Family

ID=27174888

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22230/83A IT1194339B (it) 1982-07-26 1983-07-26 Carbapenem-derivati fluoroalchilati

Country Status (18)

Country Link
US (1) US4720490A (it)
AT (1) AT386600B (it)
AU (1) AU1724183A (it)
CA (1) CA1250839A (it)
CH (1) CH661729A5 (it)
DE (1) DE3390137T1 (it)
DK (1) DK340483A (it)
ES (1) ES524424A0 (it)
FI (1) FI832619A (it)
FR (1) FR2530634B1 (it)
GB (1) GB2124625B (it)
HU (1) HUT34029A (it)
IL (1) IL69324A0 (it)
IT (1) IT1194339B (it)
NL (1) NL8302619A (it)
PT (1) PT77094B (it)
SE (1) SE462492B (it)
WO (1) WO1984000547A1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4997936A (en) * 1977-10-19 1991-03-05 Merck & Co., Inc. 2-carbamimidoyl-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids
CH662117A5 (de) * 1983-10-03 1987-09-15 Sanraku Inc Carbapenemderivate und verfahren zu ihrer herstellung.
US4665169A (en) * 1985-09-11 1987-05-12 Bristol-Myers Company Carbapenem antibiotics
EP0234484B1 (en) * 1986-02-19 1993-10-20 Sanraku Incorporated Novel azetidinone derivatives
US4948165A (en) * 1988-01-26 1990-08-14 Nissan Motor Company, Limited Proportioning valve assembly for an actively controlled suspension system
JPH09202789A (ja) * 1995-11-20 1997-08-05 Suntory Ltd ペネム誘導体およびこれを含有する抗菌剤
US7932381B2 (en) * 2005-02-15 2011-04-26 Shionogi & Co., Ltd. Process for producing carbapenem derivative and intermediate crystal therefor
CN116987278A (zh) * 2023-08-04 2023-11-03 浙江永通新材料股份有限公司 一种低温可自愈合聚硅氧烷超分子弹性体及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55147284A (en) * 1979-04-17 1980-11-17 Sanraku Inc Novel beta-lactam derivative and its preparation
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
US4235922A (en) * 1979-06-15 1980-11-25 Merck & Co., Inc. 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acid
US4372965A (en) * 1979-10-15 1983-02-08 Merck & Co., Inc. 6-, 1- And 2-substituted-thio-1-carbadethiapen-2-em-3-carboxylic acid S-oxides
US4309346A (en) * 1980-03-27 1982-01-05 Merck & Co., Inc. Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates
DE3169321D1 (en) * 1980-03-27 1985-04-25 Merck & Co Inc Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals
IE52147B1 (en) * 1980-03-27 1987-07-08 Merck & Co Inc 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0038869A1 (en) * 1980-04-30 1981-11-04 Merck & Co. Inc. Process for the preparation of 1-carbapenems, and intermediates for their preparation
EP0044170A1 (en) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-lactam antibiotics, their preparation and use
PT73791B (en) * 1980-10-17 1983-10-14 Merck & Co Inc Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids
EP0060612A1 (en) * 1981-02-04 1982-09-22 Beecham Group Plc Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
ES514240A0 (es) * 1981-08-03 1984-04-16 Merck & Co Inc Un procedimiento para la prepracion de nuevos derivados de acidos 2-carbamimidoil-1-,carbadestiapen-2-en-3-carboxilados.

Also Published As

Publication number Publication date
CH661729A5 (de) 1987-08-14
US4720490A (en) 1988-01-19
FI832619A (fi) 1984-01-27
DK340483A (da) 1984-01-27
DE3390137T1 (de) 1984-09-20
ES8506018A1 (es) 1985-06-16
FR2530634A1 (fr) 1984-01-27
GB2124625A (en) 1984-02-22
AU1724183A (en) 1984-02-02
CA1250839A (en) 1989-03-07
NL8302619A (nl) 1984-02-16
FR2530634B1 (fr) 1986-11-14
GB2124625B (en) 1986-03-19
SE8304124D0 (sv) 1983-07-25
IL69324A0 (en) 1983-11-30
ES524424A0 (es) 1985-06-16
FI832619A0 (fi) 1983-07-19
IT8322230A1 (it) 1985-01-26
IT1194339B (it) 1988-09-14
WO1984000547A1 (en) 1984-02-16
PT77094B (en) 1986-02-26
SE462492B (sv) 1990-07-02
GB8319761D0 (en) 1983-08-24
AT386600B (de) 1988-09-12
SE8304124L (sv) 1984-01-27
DK340483D0 (da) 1983-07-25
PT77094A (en) 1983-08-01
HUT34029A (en) 1985-01-28
ATA903783A (de) 1988-02-15

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