NO810422L - Farmasoeytiske preparater. - Google Patents
Farmasoeytiske preparater.Info
- Publication number
- NO810422L NO810422L NO810422A NO810422A NO810422L NO 810422 L NO810422 L NO 810422L NO 810422 A NO810422 A NO 810422A NO 810422 A NO810422 A NO 810422A NO 810422 L NO810422 L NO 810422L
- Authority
- NO
- Norway
- Prior art keywords
- glycerol
- ether
- lower alkyl
- alkyl ether
- water
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 37
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 16
- 150000005215 alkyl ethers Chemical class 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000002904 solvent Substances 0.000 claims description 10
- RXDAPJJFRLSRPX-UHFFFAOYSA-N 2,3-dimethoxypropan-1-ol Chemical compound COCC(CO)OC RXDAPJJFRLSRPX-UHFFFAOYSA-N 0.000 claims description 9
- 229960003529 diazepam Drugs 0.000 claims description 9
- AAOVKJBEBIDNHE-UHFFFAOYSA-N diazepam Chemical compound N=1CC(=O)N(C)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 AAOVKJBEBIDNHE-UHFFFAOYSA-N 0.000 claims description 9
- 239000013543 active substance Substances 0.000 claims description 5
- ZESKRVSPQJVIMH-UHFFFAOYSA-N 1,3-dimethoxypropan-2-ol Chemical compound COCC(O)COC ZESKRVSPQJVIMH-UHFFFAOYSA-N 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- 229940124530 sulfonamide Drugs 0.000 claims description 3
- 150000003456 sulfonamides Chemical class 0.000 claims description 3
- 229940049706 benzodiazepine Drugs 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 229940088594 vitamin Drugs 0.000 claims description 2
- 229930003231 vitamin Natural products 0.000 claims description 2
- 235000013343 vitamin Nutrition 0.000 claims description 2
- 239000011782 vitamin Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 8
- 239000004480 active ingredient Substances 0.000 claims 2
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 claims 1
- WZRJTRPJURQBRM-UHFFFAOYSA-N 4-amino-n-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1.COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 WZRJTRPJURQBRM-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229940006995 sulfamethoxazole and trimethoprim Drugs 0.000 claims 1
- 150000003722 vitamin derivatives Chemical class 0.000 claims 1
- 239000000243 solution Substances 0.000 description 21
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 5
- 239000002504 physiological saline solution Substances 0.000 description 4
- 229930003448 Vitamin K Natural products 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 3
- 229960000342 retinol acetate Drugs 0.000 description 3
- 235000019173 retinyl acetate Nutrition 0.000 description 3
- 239000011770 retinyl acetate Substances 0.000 description 3
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 description 3
- 235000011121 sodium hydroxide Nutrition 0.000 description 3
- 229960005404 sulfamethoxazole Drugs 0.000 description 3
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 description 3
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 3
- 229960001082 trimethoprim Drugs 0.000 description 3
- 235000019168 vitamin K Nutrition 0.000 description 3
- 239000011712 vitamin K Substances 0.000 description 3
- 150000003721 vitamin K derivatives Chemical class 0.000 description 3
- 229940046010 vitamin k Drugs 0.000 description 3
- LOSWWGJGSSQDKH-UHFFFAOYSA-N 3-ethoxypropane-1,2-diol Chemical compound CCOCC(O)CO LOSWWGJGSSQDKH-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- PJSFRIWCGOHTNF-UHFFFAOYSA-N Sulphormetoxin Chemical compound COC1=NC=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=C1OC PJSFRIWCGOHTNF-UHFFFAOYSA-N 0.000 description 2
- 229930003427 Vitamin E Natural products 0.000 description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 2
- 239000008063 pharmaceutical solvent Substances 0.000 description 2
- 229960004673 sulfadoxine Drugs 0.000 description 2
- 235000019165 vitamin E Nutrition 0.000 description 2
- 229940046009 vitamin E Drugs 0.000 description 2
- 239000011709 vitamin E Substances 0.000 description 2
- 150000001557 benzodiazepines Chemical class 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 229960004782 chlordiazepoxide Drugs 0.000 description 1
- ANTSCNMPPGJYLG-UHFFFAOYSA-N chlordiazepoxide Chemical compound O=N=1CC(NC)=NC2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 ANTSCNMPPGJYLG-UHFFFAOYSA-N 0.000 description 1
- LDBTVAXGKYIFHO-UHFFFAOYSA-N diaveridine Chemical compound C1=C(OC)C(OC)=CC=C1CC1=CN=C(N)N=C1N LDBTVAXGKYIFHO-UHFFFAOYSA-N 0.000 description 1
- 229950000246 diaveridine Drugs 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 229960004535 oxazepam Drugs 0.000 description 1
- ADIMAYPTOBDMTL-UHFFFAOYSA-N oxazepam Chemical compound C12=CC(Cl)=CC=C2NC(=O)C(O)N=C1C1=CC=CC=C1 ADIMAYPTOBDMTL-UHFFFAOYSA-N 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- CYFLXLSBHQBMFT-UHFFFAOYSA-N sulfamoxole Chemical compound O1C(C)=C(C)N=C1NS(=O)(=O)C1=CC=C(N)C=C1 CYFLXLSBHQBMFT-UHFFFAOYSA-N 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH98380 | 1980-02-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO810422L true NO810422L (no) | 1981-08-10 |
Family
ID=4199742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO810422A NO810422L (no) | 1980-02-07 | 1981-02-06 | Farmasoeytiske preparater. |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US4339447A (fi) |
| EP (1) | EP0035132B1 (fi) |
| JP (1) | JPS56125316A (fi) |
| AR (1) | AR226334A1 (fi) |
| AU (1) | AU6676481A (fi) |
| CA (1) | CA1158161A (fi) |
| DE (1) | DE3170972D1 (fi) |
| DK (1) | DK47681A (fi) |
| FI (1) | FI803846L (fi) |
| GR (1) | GR70308B (fi) |
| IE (1) | IE810231L (fi) |
| IL (1) | IL62041A0 (fi) |
| MC (1) | MC1371A1 (fi) |
| NO (1) | NO810422L (fi) |
| NZ (1) | NZ196153A (fi) |
| PH (1) | PH17121A (fi) |
| ZA (1) | ZA81650B (fi) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3343530A1 (de) * | 1983-12-01 | 1985-06-13 | Max Planck Gesellschaft | Arzneimittel mit verbesserter penetration der gewebsmembran |
| JPS60224638A (ja) * | 1984-04-23 | 1985-11-09 | Kao Corp | 経皮吸収促進剤およびこれを含有する外用剤 |
| DE3583698D1 (de) * | 1984-04-23 | 1991-09-12 | Kao Corp | Perkutaner absorptions-beschleuniger und diesen enthaltendes praeparat. |
| GB8432542D0 (en) * | 1984-12-21 | 1985-02-06 | Micropore International Ltd | Power control arrangement |
| US5462740A (en) * | 1993-09-17 | 1995-10-31 | Athena Neurosciences, Inc. | Rectally-administered, epileptic-seizure-inhibiting composition |
| CN101998828A (zh) | 2008-03-28 | 2011-03-30 | 粒子科学有限公司 | 用于使治疗剂增溶的药物溶液和方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1752305A (en) * | 1925-04-21 | 1930-04-01 | Winthrop Chem Co | Solution of medicament and process of preparing same |
| DE2038107A1 (de) * | 1970-07-31 | 1972-02-10 | Henkel & Cie Gmbh | Fluessige,gegebenenfalls als Wasch- oder Reinigungsmittel brauchbare stabilisierte Enzympraeparate |
| DE2252637C3 (de) * | 1972-10-26 | 1979-07-19 | Klinge Pharma Gmbh & Co, 8000 Muenchen | Verwendung von 1,3-Glycerindiäthern |
| DE2708419C3 (de) * | 1977-02-26 | 1979-08-16 | Basf Ag, 6700 Ludwigshafen | Verwendung von 1,2-Butandiol-lmethyläther als Lösungsmittel für pharmazeutische Injektionslösungen |
-
1980
- 1980-12-10 FI FI803846A patent/FI803846L/fi not_active Application Discontinuation
- 1980-12-18 CA CA000367043A patent/CA1158161A/en not_active Expired
-
1981
- 1981-01-07 AR AR283887A patent/AR226334A1/es active
- 1981-01-20 PH PH25104A patent/PH17121A/en unknown
- 1981-01-27 US US06/228,792 patent/US4339447A/en not_active Expired - Fee Related
- 1981-01-30 ZA ZA00810650A patent/ZA81650B/xx unknown
- 1981-01-30 NZ NZ196153A patent/NZ196153A/xx unknown
- 1981-01-30 AU AU66764/81A patent/AU6676481A/en not_active Abandoned
- 1981-02-02 IL IL62041A patent/IL62041A0/xx unknown
- 1981-02-03 DK DK47681A patent/DK47681A/da not_active Application Discontinuation
- 1981-02-04 MC MC811498A patent/MC1371A1/xx unknown
- 1981-02-04 JP JP1450281A patent/JPS56125316A/ja active Pending
- 1981-02-05 GR GR64061A patent/GR70308B/el unknown
- 1981-02-06 EP EP81100862A patent/EP0035132B1/de not_active Expired
- 1981-02-06 IE IE810231A patent/IE810231L/xx unknown
- 1981-02-06 DE DE8181100862T patent/DE3170972D1/de not_active Expired
- 1981-02-06 NO NO810422A patent/NO810422L/no unknown
-
1982
- 1982-04-26 US US06/371,621 patent/US4393073A/en not_active Expired - Fee Related
- 1982-04-26 US US06/371,400 patent/US4393057A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL62041A0 (en) | 1981-03-31 |
| JPS56125316A (en) | 1981-10-01 |
| CA1158161A (en) | 1983-12-06 |
| EP0035132A3 (en) | 1982-09-29 |
| DE3170972D1 (en) | 1985-07-25 |
| US4339447A (en) | 1982-07-13 |
| PH17121A (en) | 1984-06-01 |
| US4393057A (en) | 1983-07-12 |
| DK47681A (da) | 1981-08-08 |
| AR226334A1 (es) | 1982-06-30 |
| GR70308B (fi) | 1982-09-08 |
| FI803846L (fi) | 1981-08-08 |
| ZA81650B (en) | 1982-03-31 |
| US4393073A (en) | 1983-07-12 |
| MC1371A1 (fr) | 1982-01-19 |
| IE810231L (en) | 1981-08-07 |
| NZ196153A (en) | 1983-07-29 |
| EP0035132B1 (de) | 1985-06-19 |
| AU6676481A (en) | 1981-08-13 |
| EP0035132A2 (de) | 1981-09-09 |
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