NO334035B1 - Fremgangsmåte for fremstilling av et hyperpolarisert kontrastmiddel for magnetresonansundersøkelse - Google Patents

Fremgangsmåte for fremstilling av et hyperpolarisert kontrastmiddel for magnetresonansundersøkelse Download PDF

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Publication number
NO334035B1
NO334035B1 NO20003251A NO20003251A NO334035B1 NO 334035 B1 NO334035 B1 NO 334035B1 NO 20003251 A NO20003251 A NO 20003251A NO 20003251 A NO20003251 A NO 20003251A NO 334035 B1 NO334035 B1 NO 334035B1
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Norway
Prior art keywords
agent
polarization
solid
contrast agent
omri contrast
Prior art date
Application number
NO20003251A
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English (en)
Norwegian (no)
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NO20003251D0 (no
NO20003251L (no
Inventor
Oskar H E Axelsson
Klaes Golman
Stefan Petersson
Jan Henrik Ardenkjaer-Larsen
Georg Gunnar Hansson
Ib Leunbach
Lars-Goeran Wistrand
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Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9800158.9A external-priority patent/GB9800158D0/en
Priority claimed from GBGB9813795.3A external-priority patent/GB9813795D0/en
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of NO20003251D0 publication Critical patent/NO20003251D0/no
Publication of NO20003251L publication Critical patent/NO20003251L/no
Publication of NO334035B1 publication Critical patent/NO334035B1/no

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Signal Processing (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • General Induction Heating (AREA)
  • Magnetic Ceramics (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
NO20003251A 1998-01-05 2000-06-22 Fremgangsmåte for fremstilling av et hyperpolarisert kontrastmiddel for magnetresonansundersøkelse NO334035B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9800158.9A GB9800158D0 (en) 1998-01-05 1998-01-05 Method
GBGB9813795.3A GB9813795D0 (en) 1998-06-25 1998-06-25 Method
PCT/GB1998/003904 WO1999035508A1 (en) 1998-01-05 1998-12-23 Method of magnetic resonance investigation

Publications (3)

Publication Number Publication Date
NO20003251D0 NO20003251D0 (no) 2000-06-22
NO20003251L NO20003251L (no) 2000-06-22
NO334035B1 true NO334035B1 (no) 2013-11-25

Family

ID=26312888

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003251A NO334035B1 (no) 1998-01-05 2000-06-22 Fremgangsmåte for fremstilling av et hyperpolarisert kontrastmiddel for magnetresonansundersøkelse

Country Status (15)

Country Link
US (2) US6278893B1 (https=)
EP (2) EP2119457B1 (https=)
JP (1) JP4764548B2 (https=)
KR (1) KR100699396B1 (https=)
CN (2) CN1138154C (https=)
AU (1) AU752308C (https=)
BR (1) BRPI9813244B1 (https=)
CA (1) CA2317526C (https=)
ES (1) ES2393833T3 (https=)
HU (1) HU229718B1 (https=)
IL (1) IL136780A0 (https=)
NO (1) NO334035B1 (https=)
NZ (1) NZ505151A (https=)
RU (1) RU2221255C2 (https=)
WO (1) WO1999035508A1 (https=)

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