PL2180902T3 - Ośrodek obrazujący zawierający hiperpolaryzowany ¹³C-octan oraz jego zastosowanie - Google Patents

Ośrodek obrazujący zawierający hiperpolaryzowany ¹³C-octan oraz jego zastosowanie

Info

Publication number
PL2180902T3
PL2180902T3 PL08787477T PL08787477T PL2180902T3 PL 2180902 T3 PL2180902 T3 PL 2180902T3 PL 08787477 T PL08787477 T PL 08787477T PL 08787477 T PL08787477 T PL 08787477T PL 2180902 T3 PL2180902 T3 PL 2180902T3
Authority
PL
Poland
Prior art keywords
hyperpolarised
acetate
imaging medium
imaging
medium
Prior art date
Application number
PL08787477T
Other languages
English (en)
Inventor
Anna Gisselsson
Georg Hansson
Sven Månsson
Zandt René In't
Magnus Karlsson
Pernille R Jensen
Mathilde H Lerche
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of PL2180902T3 publication Critical patent/PL2180902T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/20—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations containing free radicals, e.g. trityl radical for overhauser

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Sorting Of Articles (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
PL08787477T 2007-08-27 2008-08-26 Ośrodek obrazujący zawierający hiperpolaryzowany ¹³C-octan oraz jego zastosowanie PL2180902T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20074367 2007-08-27
EP08787477A EP2180902B1 (en) 2007-08-27 2008-08-26 Imaging medium comprising hyperpolarised ¹³c-acetate and use thereof
PCT/EP2008/061129 WO2009027388A2 (en) 2007-08-27 2008-08-26 Imaging medium comprising hyperpolarised 13c-acetate and use thereof

Publications (1)

Publication Number Publication Date
PL2180902T3 true PL2180902T3 (pl) 2012-07-31

Family

ID=40297766

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08787477T PL2180902T3 (pl) 2007-08-27 2008-08-26 Ośrodek obrazujący zawierający hiperpolaryzowany ¹³C-octan oraz jego zastosowanie

Country Status (8)

Country Link
US (1) US20110243855A1 (pl)
EP (1) EP2180902B1 (pl)
JP (1) JP5693224B2 (pl)
CN (1) CN101854956B (pl)
AT (1) ATE534408T1 (pl)
ES (1) ES2375083T3 (pl)
PL (1) PL2180902T3 (pl)
WO (1) WO2009027388A2 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008086534A1 (en) * 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof
EP2872520B1 (en) * 2012-07-13 2016-09-14 Bracco Imaging S.p.A Triarylmethyl radicals
US10408895B2 (en) * 2013-03-15 2019-09-10 Bruker Biospin Corporation Polarization sample geometry
US9606200B2 (en) * 2013-08-27 2017-03-28 Bruker Biospin Corporation Sample-preparation method to manipulate nuclear spin-relaxation times, including to facilitate ultralow temperature hyperpolarization
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
US10921397B2 (en) * 2016-03-10 2021-02-16 Memorial Sloan Kettering Cancer Center Hyperpolarized micro-NMR system and methods
CA3044877A1 (en) 2016-11-28 2018-05-31 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
JOP20210114A1 (ar) 2018-11-23 2023-01-30 Bayer Ag تركيبة وسط تباين وعملية لتحضيرها

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413917A (en) * 1990-07-18 1995-05-09 Board Of Regents, The University Of Texas System Method of determining sources of acetyl-CoA under nonsteady-state conditions
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
US20080287774A1 (en) * 2005-11-06 2008-11-20 Rachel Katz-Brull Magnetic Resonance Imaging and Spectroscopy Means and Methods Thereof
ATE534407T1 (de) * 2005-12-01 2011-12-15 Ge Healthcare As Verfahren zur dynamischen kernpolarisation (dnp) unter verwendung eines tritylrests und eines paramagnetischen metallions
EP1962912B1 (en) * 2005-12-16 2012-09-26 Ge Healthcare As Method to produce hyperpolarised carboxylates of organic amines
EP1998813A2 (en) * 2006-03-29 2008-12-10 GE Healthcare AS Method to produce hyperpolarised carboxylates and sulphonates in the presence of inorganic cations
WO2007134160A2 (en) * 2006-05-12 2007-11-22 Massachusetts Institute Of Technology Temperature-jump dynamic nuclear polarization
CN101506179B (zh) * 2006-08-30 2012-08-22 通用电气医疗集团股份有限公司 动态核极化(dnp)的方法及用于所述方法的化合物和组合物
WO2008086534A1 (en) * 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof

Also Published As

Publication number Publication date
WO2009027388A2 (en) 2009-03-05
US20110243855A1 (en) 2011-10-06
JP2010536521A (ja) 2010-12-02
CN101854956B (zh) 2013-01-23
WO2009027388A3 (en) 2009-04-23
CN101854956A (zh) 2010-10-06
ATE534408T1 (de) 2011-12-15
ES2375083T3 (es) 2012-02-24
EP2180902B1 (en) 2011-11-23
JP5693224B2 (ja) 2015-04-01
EP2180902A2 (en) 2010-05-05

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