ATE534408T1 - Bildgebungsmedium mit hyperpolarisiertem uüc- acetat und seine verwendung - Google Patents

Bildgebungsmedium mit hyperpolarisiertem uüc- acetat und seine verwendung

Info

Publication number
ATE534408T1
ATE534408T1 AT08787477T AT08787477T ATE534408T1 AT E534408 T1 ATE534408 T1 AT E534408T1 AT 08787477 T AT08787477 T AT 08787477T AT 08787477 T AT08787477 T AT 08787477T AT E534408 T1 ATE534408 T1 AT E534408T1
Authority
AT
Austria
Prior art keywords
acetate
uuc
imaging medium
medium containing
containing hyperpolarized
Prior art date
Application number
AT08787477T
Other languages
English (en)
Inventor
Anna Gisselsson
Georg Hansson
Sven Mansson
T Zandt Rene In
Magnus Karlsson
Pernille Jensen
Mathilde Lerche
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Application granted granted Critical
Publication of ATE534408T1 publication Critical patent/ATE534408T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/20—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations containing free radicals, e.g. trityl radical for overhauser

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Sorting Of Articles (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT08787477T 2007-08-27 2008-08-26 Bildgebungsmedium mit hyperpolarisiertem uüc- acetat und seine verwendung ATE534408T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20074367 2007-08-27
PCT/EP2008/061129 WO2009027388A2 (en) 2007-08-27 2008-08-26 Imaging medium comprising hyperpolarised 13c-acetate and use thereof

Publications (1)

Publication Number Publication Date
ATE534408T1 true ATE534408T1 (de) 2011-12-15

Family

ID=40297766

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08787477T ATE534408T1 (de) 2007-08-27 2008-08-26 Bildgebungsmedium mit hyperpolarisiertem uüc- acetat und seine verwendung

Country Status (8)

Country Link
US (1) US20110243855A1 (de)
EP (1) EP2180902B1 (de)
JP (1) JP5693224B2 (de)
CN (1) CN101854956B (de)
AT (1) ATE534408T1 (de)
ES (1) ES2375083T3 (de)
PL (1) PL2180902T3 (de)
WO (1) WO2009027388A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008086534A1 (en) * 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof
EP2872520B1 (de) * 2012-07-13 2016-09-14 Bracco Imaging S.p.A Triarylmethyl-radikale
US10408895B2 (en) * 2013-03-15 2019-09-10 Bruker Biospin Corporation Polarization sample geometry
US9606200B2 (en) * 2013-08-27 2017-03-28 Bruker Biospin Corporation Sample-preparation method to manipulate nuclear spin-relaxation times, including to facilitate ultralow temperature hyperpolarization
EP3101012A1 (de) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft Neue gadoliniumchelat-verbindung zur verwendung in der magnetresonanzbildgebung
US10921397B2 (en) * 2016-03-10 2021-02-16 Memorial Sloan Kettering Cancer Center Hyperpolarized micro-NMR system and methods
CA3044877A1 (en) 2016-11-28 2018-05-31 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
JOP20210114A1 (ar) 2018-11-23 2023-01-30 Bayer Ag تركيبة وسط تباين وعملية لتحضيرها

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413917A (en) * 1990-07-18 1995-05-09 Board Of Regents, The University Of Texas System Method of determining sources of acetyl-CoA under nonsteady-state conditions
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
US20080287774A1 (en) * 2005-11-06 2008-11-20 Rachel Katz-Brull Magnetic Resonance Imaging and Spectroscopy Means and Methods Thereof
ATE534407T1 (de) * 2005-12-01 2011-12-15 Ge Healthcare As Verfahren zur dynamischen kernpolarisation (dnp) unter verwendung eines tritylrests und eines paramagnetischen metallions
EP1962912B1 (de) * 2005-12-16 2012-09-26 Ge Healthcare As Verfahren zur herstellung hyperpolarisierter carboxylate organischer amine
EP1998813A2 (de) * 2006-03-29 2008-12-10 GE Healthcare AS Verfahren zur herstellung hyperpolaisierter carboxylate und sulfonate in gegenwart von anorganischen kationen
WO2007134160A2 (en) * 2006-05-12 2007-11-22 Massachusetts Institute Of Technology Temperature-jump dynamic nuclear polarization
CN101506179B (zh) * 2006-08-30 2012-08-22 通用电气医疗集团股份有限公司 动态核极化(dnp)的方法及用于所述方法的化合物和组合物
WO2008086534A1 (en) * 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof

Also Published As

Publication number Publication date
WO2009027388A2 (en) 2009-03-05
US20110243855A1 (en) 2011-10-06
JP2010536521A (ja) 2010-12-02
CN101854956B (zh) 2013-01-23
WO2009027388A3 (en) 2009-04-23
CN101854956A (zh) 2010-10-06
ES2375083T3 (es) 2012-02-24
EP2180902B1 (de) 2011-11-23
JP5693224B2 (ja) 2015-04-01
EP2180902A2 (de) 2010-05-05
PL2180902T3 (pl) 2012-07-31

Similar Documents

Publication Publication Date Title
ATE534408T1 (de) Bildgebungsmedium mit hyperpolarisiertem uüc- acetat und seine verwendung
IL197606A (en) Optical signal field restoration and restoration
BR112013024768A2 (pt) modulação de expressão de transdutor de sinal e ativador de transcrição 3 (stat 3)
BR112012000934A2 (pt) cassetes e métodos de utilizacao destes
NO345031B1 (no) System og fremgangsmåte for forvaltning av stigerørs livssyklus
GB2495238B (en) System for sensing human movement and methods of using the same
CO6640258A2 (es) Formulaciones de anticuerpos de alta concentración
EP2115492A4 (de) Direktzeiterfassungsumkehrung von seismischen daten
NL2002411A1 (nl) System and method for tissue specific MR imaging of metabolites using spectral-spatially formed stimulated echo.
BRPI0907272A2 (pt) "método de avaliação e aparelho de avaliação de perfusão de vasos perfurantes"
BRPI0908951A2 (pt) compostos de minociclina e método de uso dos mesmos
NO20091829L (no) Beregning av verdier for a undersoke en underjordisk struktur basert pa malinger i henhold til ulike elektromagnetiske undersokelsesteknikker
BRPI0906387A2 (pt) Anticorpos alfa 5 - beta 1 e seus usos
HU0700807D0 (en) Arrangement and method for detection and/or measurement of respiration
EP2606327A4 (de) Thermometer zur bestimmung der temperatur des trommelfells eines tieres und verwendungsverfahren dafür
WO2009013350A3 (en) Imaging medium comprising hyperpolarised 13 c-lactate and use thereof
SI2338157T1 (sl) Naprava za online merjenje toka hitrih in epitermičnih nevtronov
BR112012015877A2 (pt) dispositivo de exibição de informações de programa, método de exibição de informações de programa, programa, e meio de gravação
ATE549638T1 (de) 13c-mr-bildgebung oder spektroskopie von zelltod
MX2010002193A (es) Metodo de determinacion de actividad pdh y generacion de imagen para su uso en dicho metodo.
EP2332119A4 (de) Aufzeichnung und/oder verwendung von generierungsinformationen
BR112012003469A2 (pt) "dispositivo e método de pré-concentração.
ATE544474T1 (de) Magnetresonanz-abbildungsmittel, abbildungsmedium und verfahren zur abbildung, worin solch ein abbildungsmedium verwendet wird
FR2960068B1 (fr) Dispositif de detection et de denombrement d'elements metalliques
GB0814968D0 (en) Device for detecting skin sensitivity and use of the same