NO332460B1 - Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling. - Google Patents

Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling. Download PDF

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Publication number
NO332460B1
NO332460B1 NO20012223A NO20012223A NO332460B1 NO 332460 B1 NO332460 B1 NO 332460B1 NO 20012223 A NO20012223 A NO 20012223A NO 20012223 A NO20012223 A NO 20012223A NO 332460 B1 NO332460 B1 NO 332460B1
Authority
NO
Norway
Prior art keywords
nogo
protein
nucleic acid
sequence
seq
Prior art date
Application number
NO20012223A
Other languages
English (en)
Norwegian (no)
Other versions
NO20012223D0 (no
NO20012223L (no
Inventor
Martin E Schwab
Maio S Chen
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO332460(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Zuerich filed Critical Univ Zuerich
Publication of NO20012223D0 publication Critical patent/NO20012223D0/no
Publication of NO20012223L publication Critical patent/NO20012223L/no
Publication of NO332460B1 publication Critical patent/NO332460B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
NO20012223A 1998-11-06 2001-05-04 Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling. NO332460B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon

Publications (3)

Publication Number Publication Date
NO20012223D0 NO20012223D0 (no) 2001-05-04
NO20012223L NO20012223L (no) 2001-07-02
NO332460B1 true NO332460B1 (no) 2012-09-24

Family

ID=22316666

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012223A NO332460B1 (no) 1998-11-06 2001-05-04 Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling.

Country Status (27)

Country Link
US (4) US7781188B1 (ja)
EP (3) EP2093294B1 (ja)
JP (2) JP2003531566A (ja)
KR (1) KR100728405B1 (ja)
CN (3) CN1721444A (ja)
AT (1) ATE435232T1 (ja)
AU (1) AU774367C (ja)
BR (1) BR9915137A (ja)
CA (1) CA2350395C (ja)
CY (1) CY1110679T1 (ja)
CZ (1) CZ304224B6 (ja)
DE (1) DE69941059D1 (ja)
DK (1) DK1124846T3 (ja)
ES (2) ES2529196T3 (ja)
HK (1) HK1038027A1 (ja)
HU (1) HUP0301829A3 (ja)
IL (3) IL142989A0 (ja)
MX (1) MXPA01004598A (ja)
NO (1) NO332460B1 (ja)
NZ (1) NZ511683A (ja)
PL (1) PL204293B1 (ja)
PT (1) PT1124846E (ja)
RU (3) RU2304585C2 (ja)
SK (1) SK287323B6 (ja)
TR (1) TR200700740T2 (ja)
WO (1) WO2000031235A2 (ja)
ZA (1) ZA200103714B (ja)

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US20020072493A1 (en) 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
EP2264174A3 (en) * 1998-07-22 2012-03-07 SmithKline Beecham Limited Protein similar to neuroendocrine-specific protein, and encoding CDNA
CN1721444A (zh) 1998-11-06 2006-01-18 苏黎世大学 Nogo基因的核苷酸序列和蛋白序列以及基于其的方法
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
WO2000060083A1 (en) * 1999-04-08 2000-10-12 Chiron Corporation Novel protein associated with cell stress response
NZ520065A (en) * 2000-01-12 2006-02-24 Univ Yale Nogo receptor-mediated blockade of axonal growth
US7119165B2 (en) 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
DK1325130T3 (da) * 2000-10-06 2010-05-25 Univ Yale Nogo-Receptorhomologer
GB0101312D0 (en) 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
TWI323265B (en) 2002-08-06 2010-04-11 Glaxo Group Ltd Antibodies
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
WO2004039836A1 (en) * 2002-10-31 2004-05-13 Pieris Proteolab Ag Soluble truncated polypeptides of the nogo-a protein
EP1606409B1 (en) 2003-03-19 2010-09-01 Biogen Idec MA Inc. Nogo receptor binding protein
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
JP4901480B2 (ja) * 2003-12-22 2012-03-21 グラクソ グループ リミテッド 神経疾患治療用の、nogo−aを中和する免疫グロブリン
JP4960865B2 (ja) 2004-06-24 2012-06-27 バイオジェン・アイデック・エムエイ・インコーポレイテッド 脱髄に関連する状態の処置
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
US20090137484A1 (en) * 2004-12-01 2009-05-28 National University Of Singapore Neuronal Network-Interacting Peptide
US7893032B2 (en) 2005-07-07 2011-02-22 Yale University NgR variants and compositions thereof for suppressing axonal growth inhibition
KR101245462B1 (ko) 2005-07-08 2013-03-20 바이오겐 아이덱 엠에이 인코포레이티드 Sp35 항체 및 그의 용도
US20070026463A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant Nogo-66 domain proteins
KR20080073748A (ko) 2005-11-16 2008-08-11 노파르티스 아게 척수 손상에서의 항-nogo-a 항체 치료를 위한바이오마커
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
CA2653456A1 (en) * 2006-05-24 2007-11-29 Richard Daneman Permeability of blood-brain barrier
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
MY149546A (en) * 2007-11-02 2013-09-13 Novartis Ag Improved nogo-a binding molecules and pharmaceutical use tereof
BRPI0820221A2 (pt) * 2007-11-22 2015-05-26 Symphogen As Método para caracterização de uma proteína policlonal recombinante
EP2315779A2 (en) 2008-07-09 2011-05-04 Biogen Idec MA Inc. Compositions comprising antibodies to lingo or fragments thereof
KR20120122869A (ko) * 2009-06-02 2012-11-07 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 신경변성 질환을 갖는 대상에서 항체에 의해 인식되는 소분자의 확인법
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
CN104470541A (zh) 2012-05-14 2015-03-25 比奥根艾迪克Ma公司 用于治疗涉及运动神经元的疾患的lingo-2拮抗剂
ES2647789T3 (es) 2013-08-08 2017-12-26 Global Bio Therapeutics, Inc. Dispositivo de inyección para procedimientos mínimamente invasivos
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
US10435467B2 (en) 2015-01-08 2019-10-08 Biogen Ma Inc. LINGO-1 antagonists and uses for treatment of demyelinating disorders
EP3250220B1 (en) * 2015-01-27 2020-03-11 Universität Zürich Agonists of the nogo-a s1pr pathway for the treatment of glioblastoma

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US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
CA1173823A (en) 1980-08-26 1984-09-04 Leonard M. Hjelmeland Nondenaturing zwitterionic detergent for membrane biochemistry
CA1341401C (en) 1984-03-23 2002-11-26 Adriano Fontana Immunosuppressant factor derived from human glioblastoma cells
EP0155433A1 (en) 1984-03-23 1985-09-25 Adriano Fontana Immunosuppressant factor
EP0233838A3 (en) 1986-02-04 1990-01-31 Incyte Pharmaceuticals, Inc. Neurite-promoting factor and process for the manufacture thereof
WO1989012690A1 (en) 1988-06-13 1989-12-28 American Biogentic Sciences, Inc. Method for the production of monoclonal antibodies utilizing a germfree animal
CA1341050C (en) * 1988-11-04 2000-07-11 Martin E. Schwab Neurite growth regulatory factors
US5250414A (en) 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
EP0396719B1 (en) 1988-11-04 1995-07-05 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
AU2152092A (en) * 1991-06-24 1993-01-25 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
US5858708A (en) * 1996-08-12 1999-01-12 Bandman; Olga Polynucleotides encoding two novel human neuroendocrine-specific proteins
CA2269755A1 (en) * 1996-10-25 1998-04-30 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
EP1042470A2 (en) * 1997-12-30 2000-10-11 Chiron Corporation Bone marrow secreted proteins and polynucleotides
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
EP2264174A3 (en) 1998-07-22 2012-03-07 SmithKline Beecham Limited Protein similar to neuroendocrine-specific protein, and encoding CDNA
CA2340616A1 (en) * 1998-08-24 2000-03-02 Alphagene, Inc. Secreted proteins and polynucleotides encoding them
CN1721444A (zh) 1998-11-06 2006-01-18 苏黎世大学 Nogo基因的核苷酸序列和蛋白序列以及基于其的方法
EP1147192A1 (en) * 1999-11-15 2001-10-24 Smithkline Beecham Plc Human nogo-c polynucleotide and polypeptide and their uses
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Also Published As

Publication number Publication date
KR20020003353A (ko) 2002-01-12
AU1469200A (en) 2000-06-13
NO20012223D0 (no) 2001-05-04
EP2093294B1 (en) 2014-10-29
CY1110679T1 (el) 2015-06-10
US7781188B1 (en) 2010-08-24
CN1721444A (zh) 2006-01-18
CA2350395A1 (en) 2000-06-02
CZ20011608A3 (cs) 2001-10-17
RU2432364C2 (ru) 2011-10-27
PL204293B1 (pl) 2009-12-31
EP1124846A2 (en) 2001-08-22
IL198027A (en) 2011-10-31
NO20012223L (no) 2001-07-02
SK287323B6 (sk) 2010-07-07
IL142989A (en) 2010-12-30
CA2350395C (en) 2014-07-08
CN1354755B (zh) 2010-06-02
RU2304585C2 (ru) 2007-08-20
US7425334B2 (en) 2008-09-16
AU774367B2 (en) 2004-06-24
RU2009103533A (ru) 2010-11-10
US20110086034A1 (en) 2011-04-14
ES2329635T3 (es) 2009-11-27
AU774367C (en) 2005-04-21
JP2003531566A (ja) 2003-10-28
HUP0301829A2 (hu) 2003-08-28
CN101684155A (zh) 2010-03-31
EP1124846B1 (en) 2009-07-01
ZA200103714B (en) 2004-06-25
NZ511683A (en) 2004-06-25
ATE435232T1 (de) 2009-07-15
DK1124846T3 (da) 2009-10-26
SK6222001A3 (en) 2001-12-03
BR9915137A (pt) 2004-06-08
US20090162367A1 (en) 2009-06-25
CN1354755A (zh) 2002-06-19
TR200700740T2 (tr) 2007-04-24
ES2529196T3 (es) 2015-02-17
RU2358982C2 (ru) 2009-06-20
EP1124846A4 (en) 2002-06-12
KR100728405B1 (ko) 2007-06-13
MXPA01004598A (es) 2002-04-24
PT1124846E (pt) 2009-10-08
PL362990A1 (en) 2004-11-15
RU2004103555A (ru) 2005-07-20
IL142989A0 (en) 2002-04-21
EP2093294A1 (en) 2009-08-26
HK1038027A1 (en) 2002-03-01
RU2001115705A (ru) 2004-03-10
WO2000031235A3 (en) 2000-11-09
US20050260616A1 (en) 2005-11-24
HUP0301829A3 (en) 2009-03-30
DE69941059D1 (de) 2009-08-13
EP2333064A1 (en) 2011-06-15
WO2000031235A2 (en) 2000-06-02
JP2012213406A (ja) 2012-11-08
CZ304224B6 (cs) 2014-01-15

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