NO329246B1 - Fremgangsmate for fremstilling av proteiner ved autoproteolytisk spalting ved bruk av ekspresjonsvektor og bakterievertscelle - Google Patents
Fremgangsmate for fremstilling av proteiner ved autoproteolytisk spalting ved bruk av ekspresjonsvektor og bakterievertscelle Download PDFInfo
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- NO329246B1 NO329246B1 NO20020507A NO20020507A NO329246B1 NO 329246 B1 NO329246 B1 NO 329246B1 NO 20020507 A NO20020507 A NO 20020507A NO 20020507 A NO20020507 A NO 20020507A NO 329246 B1 NO329246 B1 NO 329246B1
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- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
- C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT136899 | 1999-08-09 | ||
| PCT/EP2000/007642 WO2001011056A1 (en) | 1999-08-09 | 2000-08-07 | Production of proteins by autoproteolytic cleavage |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20020507D0 NO20020507D0 (no) | 2002-01-31 |
| NO20020507L NO20020507L (no) | 2002-04-05 |
| NO329246B1 true NO329246B1 (no) | 2010-09-20 |
Family
ID=3512383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20020507A NO329246B1 (no) | 1999-08-09 | 2002-01-31 | Fremgangsmate for fremstilling av proteiner ved autoproteolytisk spalting ved bruk av ekspresjonsvektor og bakterievertscelle |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7378512B2 (tr) |
| EP (1) | EP1200603B1 (tr) |
| JP (1) | JP5480458B2 (tr) |
| KR (1) | KR100735791B1 (tr) |
| CN (1) | CN1230542C (tr) |
| AU (1) | AU775681B2 (tr) |
| CA (1) | CA2380302C (tr) |
| CZ (1) | CZ303341B6 (tr) |
| HK (1) | HK1047127B (tr) |
| HU (1) | HU230117B1 (tr) |
| IL (2) | IL147411A0 (tr) |
| MX (1) | MXPA02001425A (tr) |
| NO (1) | NO329246B1 (tr) |
| PL (1) | PL203708B1 (tr) |
| SK (1) | SK288290B6 (tr) |
| TR (1) | TR200200048T2 (tr) |
| WO (1) | WO2001011056A1 (tr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2823220B1 (fr) | 2001-04-04 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo) |
| JP2005510244A (ja) * | 2001-11-26 | 2005-04-21 | ザ・ユニヴァーシティ・オヴ・クイーンズランド | フラビウイルスワクチン送達系 |
| GB0508435D0 (en) * | 2005-04-26 | 2005-06-01 | Sandoz Ag | Organic compounds |
| JP2008538897A (ja) | 2005-04-26 | 2008-11-13 | サンド・アクチエンゲゼルシヤフト | 融合タンパク質の自己タンパク質分解切断による組換えタンパク質の産生 |
| AU2011253661B2 (en) * | 2005-04-26 | 2013-06-13 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Production of recombinant proteins by autoproteolytic cleavage of a fusion protein |
| GB0508434D0 (en) * | 2005-04-26 | 2005-06-01 | Sandoz Ag | Organic compounds |
| US20100137563A1 (en) * | 2008-12-03 | 2010-06-03 | Northwestern University | Cysteine Protease Autoprocessing of Fusion Proteins |
| EP2684951A1 (en) | 2012-07-13 | 2014-01-15 | Sandoz Ag | Method for producing a recombinant protein of interest |
| EP2746390A1 (en) | 2012-12-19 | 2014-06-25 | Sandoz Ag | Method for producing a recombinant protein of interest |
| EP2746391A1 (en) | 2012-12-19 | 2014-06-25 | Sandoz Ag | Method for producing a recombinant protein of interest |
| UY35874A (es) | 2013-12-12 | 2015-07-31 | Novartis Ag | Un proceso para la preparación de una composición de proteínas pegiladas |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743679A (en) * | 1986-02-24 | 1988-05-10 | Creative Biomolecules, Inc. | Process for producing human epidermal growth factor and analogs thereof |
| EP0321973B1 (de) * | 1987-12-23 | 1993-11-03 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Expression der viral kodierten Protease P2A des HRV2 |
| US6077694A (en) * | 1990-09-21 | 2000-06-20 | The United States Of America As Represented By The Department Of Health And Human Services | Method for over-expression and rapid purification of biosynthetic proteins |
| MX219629B (es) * | 1997-04-25 | 2004-03-30 | Sembiosys Genetics Inc | Metodo para separar proteinas de fusion |
| DE59812768D1 (de) * | 1997-08-22 | 2005-06-09 | Roche Diagnostics Gmbh | Autokatalytisch aktivierbare zymogene vorstufen von proteasen und deren verwendung |
| WO1999010483A2 (de) * | 1997-08-22 | 1999-03-04 | Roche Diagnostics Gmbh | Autokatalytisch aktivierbare vorstufen von proteasen und deren verwendung |
| HU230231B1 (hu) * | 1999-08-09 | 2015-10-28 | Sandoz Ag | Fehérjék termelése |
-
2000
- 2000-08-07 EP EP00954596.3A patent/EP1200603B1/en not_active Expired - Lifetime
- 2000-08-07 HU HU0203051A patent/HU230117B1/hu unknown
- 2000-08-07 AU AU66998/00A patent/AU775681B2/en not_active Expired
- 2000-08-07 JP JP2001515841A patent/JP5480458B2/ja not_active Expired - Lifetime
- 2000-08-07 IL IL14741100A patent/IL147411A0/xx unknown
- 2000-08-07 CN CNB008110719A patent/CN1230542C/zh not_active Expired - Lifetime
- 2000-08-07 SK SK187-2002A patent/SK288290B6/sk not_active IP Right Cessation
- 2000-08-07 WO PCT/EP2000/007642 patent/WO2001011056A1/en active IP Right Grant
- 2000-08-07 CZ CZ20020480A patent/CZ303341B6/cs not_active IP Right Cessation
- 2000-08-07 CA CA2380302A patent/CA2380302C/en not_active Expired - Lifetime
- 2000-08-07 KR KR1020027001667A patent/KR100735791B1/ko active IP Right Grant
- 2000-08-07 TR TR2002/00048T patent/TR200200048T2/tr unknown
- 2000-08-07 MX MXPA02001425A patent/MXPA02001425A/es active IP Right Grant
- 2000-08-07 PL PL353090A patent/PL203708B1/pl unknown
-
2001
- 2001-12-31 IL IL147411A patent/IL147411A/en active IP Right Grant
-
2002
- 2002-01-31 NO NO20020507A patent/NO329246B1/no not_active IP Right Cessation
- 2002-09-24 HK HK02106953.0A patent/HK1047127B/zh not_active IP Right Cessation
-
2004
- 2004-01-23 US US10/763,619 patent/US7378512B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU6699800A (en) | 2001-03-05 |
| PL203708B1 (pl) | 2009-11-30 |
| JP2003506092A (ja) | 2003-02-18 |
| JP5480458B2 (ja) | 2014-04-23 |
| EP1200603B1 (en) | 2014-12-24 |
| HUP0203051A2 (hu) | 2002-12-28 |
| TR200200048T2 (tr) | 2002-04-22 |
| AU775681B2 (en) | 2004-08-12 |
| CZ2002480A3 (cs) | 2002-05-15 |
| HK1047127A1 (en) | 2003-02-07 |
| HUP0203051A3 (en) | 2003-12-29 |
| PL353090A1 (en) | 2003-10-06 |
| MXPA02001425A (es) | 2002-08-12 |
| KR100735791B1 (ko) | 2007-07-06 |
| WO2001011056A1 (en) | 2001-02-15 |
| CA2380302C (en) | 2013-02-26 |
| SK288290B6 (sk) | 2015-07-01 |
| EP1200603A1 (en) | 2002-05-02 |
| CA2380302A1 (en) | 2001-02-15 |
| CN1367837A (zh) | 2002-09-04 |
| HK1047127B (zh) | 2015-08-21 |
| IL147411A (en) | 2013-12-31 |
| CZ303341B6 (cs) | 2012-08-08 |
| HU230117B1 (hu) | 2015-08-28 |
| KR20020021175A (ko) | 2002-03-18 |
| NO20020507L (no) | 2002-04-05 |
| US20040215008A1 (en) | 2004-10-28 |
| SK1872002A3 (en) | 2002-07-02 |
| NO20020507D0 (no) | 2002-01-31 |
| US7378512B2 (en) | 2008-05-27 |
| IL147411A0 (en) | 2002-08-14 |
| CN1230542C (zh) | 2005-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |