NO324272B1 - Humaniserte antistoff mot humant gp39, sammensetninger inneholdende dette, samt anvendelse derav ved fremstilling av medikamenter - Google Patents
Humaniserte antistoff mot humant gp39, sammensetninger inneholdende dette, samt anvendelse derav ved fremstilling av medikamenter Download PDFInfo
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- NO324272B1 NO324272B1 NO19982062A NO982062A NO324272B1 NO 324272 B1 NO324272 B1 NO 324272B1 NO 19982062 A NO19982062 A NO 19982062A NO 982062 A NO982062 A NO 982062A NO 324272 B1 NO324272 B1 NO 324272B1
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- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
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- C07K16/467—Igs with modifications in the FR-residues only
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/554,840 US6001358A (en) | 1995-11-07 | 1995-11-07 | Humanized antibodies to human gp39, compositions containing thereof |
PCT/US1996/017875 WO1997017446A2 (fr) | 1995-11-07 | 1996-11-07 | ANTICORPS HUMANISES DIRIGES CONTRE LA gp39 D'ORIGINE HUMAINE, COMPOSITIONS CONTENANT CES ANTICORPS ET LEUR UTILISATION THERAPEUTIQUE |
Publications (3)
Publication Number | Publication Date |
---|---|
NO982062D0 NO982062D0 (no) | 1998-05-06 |
NO982062L NO982062L (no) | 1998-07-06 |
NO324272B1 true NO324272B1 (no) | 2007-09-17 |
Family
ID=24214905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19982062A NO324272B1 (no) | 1995-11-07 | 1998-05-06 | Humaniserte antistoff mot humant gp39, sammensetninger inneholdende dette, samt anvendelse derav ved fremstilling av medikamenter |
Country Status (11)
Country | Link |
---|---|
US (4) | US6001358A (fr) |
EP (1) | EP0862630B1 (fr) |
JP (1) | JP2000500334A (fr) |
KR (1) | KR100389711B1 (fr) |
AT (1) | ATE364699T1 (fr) |
AU (1) | AU717762B2 (fr) |
DE (1) | DE69637131T2 (fr) |
HU (1) | HUP9902327A3 (fr) |
NO (1) | NO324272B1 (fr) |
NZ (1) | NZ324500A (fr) |
WO (1) | WO1997017446A2 (fr) |
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EP3816290A4 (fr) | 2018-06-26 | 2022-03-30 | Kyowa Kirin Co., Ltd. | Anticorps se liant à la molécule d'adhésion cellulaire 3 |
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CA3125316A1 (fr) | 2018-12-28 | 2020-07-02 | Kyowa Kirin Co., Ltd. | Anticorps bispecifique lie au recepteur de la transferrine (tfr) |
JPWO2020230901A1 (fr) | 2019-05-15 | 2020-11-19 | ||
TW202108626A (zh) | 2019-05-15 | 2021-03-01 | 日商協和麒麟股份有限公司 | 與cd40及fap結合之雙專一性抗體 |
EP4039814A4 (fr) | 2019-10-02 | 2023-10-11 | Kyushu University, National University Corporation | Procédé de production d'une substance du type héparine, cellules recombinantes et leur procédé de production |
TW202140561A (zh) | 2020-02-14 | 2021-11-01 | 日商協和麒麟股份有限公司 | 與cd3結合之雙特異性抗體 |
KR20220161337A (ko) | 2020-04-01 | 2022-12-06 | 쿄와 기린 가부시키가이샤 | 항체 조성물 |
CN111690061B (zh) * | 2020-06-28 | 2022-08-23 | 中国人民解放军东部战区疾病预防控制中心 | 人源化抗鼠疫耶尔森菌抗原f1的抗体及应用 |
WO2023027177A1 (fr) | 2021-08-26 | 2023-03-02 | 協和キリン株式会社 | Anticorps bispécifique se liant à cd116 et cd131 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
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GB8308235D0 (en) * | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4978745A (en) * | 1987-11-23 | 1990-12-18 | Centocor, Inc. | Immunoreactive heterochain antibodies |
US4975369A (en) * | 1988-04-21 | 1990-12-04 | Eli Lilly And Company | Recombinant and chimeric KS1/4 antibodies directed against a human adenocarcinoma antigen |
IL162181A (en) * | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
EP0519596B1 (fr) * | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | Procédé pour réduire l'immunogénicité des domaines variables d'anticorps |
DE69233402T3 (de) | 1991-10-25 | 2009-06-25 | Immunex Corp., Seattle | Neue cytokine |
US5474771A (en) * | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
CA2089229C (fr) | 1992-02-14 | 2010-04-13 | Alejandro A. Aruffo | Recepteur cd40cr et ligands pour celui-ci |
AU5098493A (en) * | 1992-08-21 | 1994-03-15 | Schering Corporation | Cd40 ligand, anti cd40 antibodies, and soluble cd40 |
US5540926A (en) | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
JP2991499B2 (ja) * | 1993-09-02 | 1999-12-20 | トラスティーズ・オブ・ダートマス・カレッジ | 抗gp39抗体およびその用途 |
ES2134954T3 (es) | 1993-09-02 | 1999-10-16 | Dartmouth College | Procedimiento de supresion prolongada de la inmunidad humoral. |
US5683693A (en) | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
US5876950A (en) * | 1995-01-26 | 1999-03-02 | Bristol-Myers Squibb Company | Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy |
US6440418B1 (en) | 1995-11-07 | 2002-08-27 | Idec Pharmaceuticals Corporation | Methods of treating autoimmune diseases with gp39-specific antibodies |
US6001358A (en) * | 1995-11-07 | 1999-12-14 | Idec Pharmaceuticals Corporation | Humanized antibodies to human gp39, compositions containing thereof |
AU4352997A (en) | 1996-08-30 | 1998-03-19 | Genzyme Corporation | Inhibition of primary and/or secondary immune response to repeat adenoviral vector administration using cd40l specific antibodies |
-
1995
- 1995-11-07 US US08/554,840 patent/US6001358A/en not_active Expired - Fee Related
-
1996
- 1996-11-07 EP EP96942732A patent/EP0862630B1/fr not_active Expired - Lifetime
- 1996-11-07 DE DE69637131T patent/DE69637131T2/de not_active Expired - Fee Related
- 1996-11-07 AU AU11576/97A patent/AU717762B2/en not_active Ceased
- 1996-11-07 JP JP9518328A patent/JP2000500334A/ja active Pending
- 1996-11-07 KR KR10-1998-0703380A patent/KR100389711B1/ko not_active IP Right Cessation
- 1996-11-07 AT AT96942732T patent/ATE364699T1/de not_active IP Right Cessation
- 1996-11-07 HU HU9902327A patent/HUP9902327A3/hu unknown
- 1996-11-07 NZ NZ324500A patent/NZ324500A/xx unknown
- 1996-11-07 WO PCT/US1996/017875 patent/WO1997017446A2/fr active IP Right Grant
-
1998
- 1998-05-06 NO NO19982062A patent/NO324272B1/no unknown
-
1999
- 1999-06-14 US US09/332,595 patent/US6506383B1/en not_active Expired - Fee Related
-
2002
- 2002-06-17 US US10/171,680 patent/US7074406B2/en not_active Expired - Fee Related
-
2006
- 2006-03-09 US US11/370,899 patent/US20060147446A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1997017446A3 (fr) | 1997-09-25 |
DE69637131T2 (de) | 2008-02-07 |
NO982062L (no) | 1998-07-06 |
US20030175269A1 (en) | 2003-09-18 |
HUP9902327A3 (en) | 2000-12-28 |
US6506383B1 (en) | 2003-01-14 |
AU717762B2 (en) | 2000-03-30 |
WO1997017446A2 (fr) | 1997-05-15 |
KR19990067370A (ko) | 1999-08-16 |
NZ324500A (en) | 1999-08-30 |
ATE364699T1 (de) | 2007-07-15 |
US6001358A (en) | 1999-12-14 |
US7074406B2 (en) | 2006-07-11 |
EP0862630A2 (fr) | 1998-09-09 |
US20060147446A1 (en) | 2006-07-06 |
HUP9902327A2 (hu) | 1999-10-28 |
KR100389711B1 (ko) | 2003-10-30 |
EP0862630B1 (fr) | 2007-06-13 |
AU1157697A (en) | 1997-05-29 |
JP2000500334A (ja) | 2000-01-18 |
NO982062D0 (no) | 1998-05-06 |
DE69637131D1 (de) | 2007-07-26 |
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