NO323937B1 - Rekombinante hjelpe baculovirus samt fremgangsmate for fremstilling av rekombinante virus. - Google Patents

Rekombinante hjelpe baculovirus samt fremgangsmate for fremstilling av rekombinante virus. Download PDF

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Publication number
NO323937B1
NO323937B1 NO19992464A NO992464A NO323937B1 NO 323937 B1 NO323937 B1 NO 323937B1 NO 19992464 A NO19992464 A NO 19992464A NO 992464 A NO992464 A NO 992464A NO 323937 B1 NO323937 B1 NO 323937B1
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Norway
Prior art keywords
baculovirus
genome
recombinant
defective
adenovirus
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NO19992464A
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English (en)
Norwegian (no)
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NO992464L (no
NO992464D0 (no
Inventor
Patrice Yeh
Emmanuelle Vigne
Michel Perricaudet
Helene Leblois-Prehaud
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Centelion
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Application filed by Centelion filed Critical Centelion
Publication of NO992464D0 publication Critical patent/NO992464D0/no
Publication of NO992464L publication Critical patent/NO992464L/no
Publication of NO323937B1 publication Critical patent/NO323937B1/no

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    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/14011Baculoviridae
    • C12N2710/14041Use of virus, viral particle or viral elements as a vector
    • C12N2710/14043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vectore
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/14011Baculoviridae
    • C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2800/00Nucleic acids vectors
    • C12N2800/30Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/001Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pens And Brushes (AREA)
  • Materials For Medical Uses (AREA)
NO19992464A 1996-11-22 1999-05-21 Rekombinante hjelpe baculovirus samt fremgangsmate for fremstilling av rekombinante virus. NO323937B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9614278A FR2756297B1 (fr) 1996-11-22 1996-11-22 Procede de production de virus recombinants
PCT/FR1997/002073 WO1998022607A1 (fr) 1996-11-22 1997-11-18 Procede de production de virus recombinants

Publications (3)

Publication Number Publication Date
NO992464D0 NO992464D0 (no) 1999-05-21
NO992464L NO992464L (no) 1999-06-23
NO323937B1 true NO323937B1 (no) 2007-07-23

Family

ID=9497899

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19992464A NO323937B1 (no) 1996-11-22 1999-05-21 Rekombinante hjelpe baculovirus samt fremgangsmate for fremstilling av rekombinante virus.
NO2013009C NO2013009I1 (no) 1996-11-22 2013-04-15 Alipogen tiparvovec

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2013009C NO2013009I1 (no) 1996-11-22 2013-04-15 Alipogen tiparvovec

Country Status (18)

Country Link
US (2) US6387670B1 (cs)
EP (1) EP0946741B1 (cs)
JP (1) JP4686670B2 (cs)
KR (1) KR100719645B1 (cs)
AT (1) ATE317908T1 (cs)
AU (1) AU731106B2 (cs)
BR (1) BR9713388B1 (cs)
CA (1) CA2271438C (cs)
CZ (1) CZ293947B6 (cs)
DE (1) DE69735274T2 (cs)
ES (1) ES2260803T3 (cs)
FR (1) FR2756297B1 (cs)
HU (1) HU224713B1 (cs)
IL (1) IL129686A (cs)
NO (2) NO323937B1 (cs)
SK (1) SK286900B6 (cs)
WO (1) WO1998022607A1 (cs)
ZA (1) ZA9710516B (cs)

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US6793926B1 (en) * 1999-05-27 2004-09-21 Genovo, Inc. Methods for production of a recombinant adeno-associated virus
WO2000073480A1 (en) * 1999-05-27 2000-12-07 Genovo, Incorporated Compositions and methods for production of recombinant virus using a carrier vector derived from a nonmammalian virus
WO2000073424A1 (en) * 1999-05-28 2000-12-07 Mount Sinai School Of Medicine A novel baculovirus/adenovirus hybrid vector for the rescue, production and titration of high-capacity adenovirus amplicon vectors
GB9919409D0 (en) 1999-08-18 1999-10-20 Univ Oxford Brookes Baculovirus expression system
EP2801614B1 (en) 2002-08-29 2019-05-15 The Board of Trustees of the Leland Stanford Junior University Circular nucleic acid vectors and methods for making and using the same
GB0702695D0 (en) * 2007-02-12 2007-03-21 Ark Therapeutics Ltd Production of vectors
GB0702694D0 (en) * 2007-02-12 2007-03-21 Ark Therapeutics Ltd Vectors
EP2019143A1 (en) 2007-07-23 2009-01-28 Genethon CNS gene delivery using peripheral administration of AAV vectors
EP2058401A1 (en) 2007-10-05 2009-05-13 Genethon Widespread gene delivery to motor neurons using peripheral injection of AAV vectors
CA2717354C (en) * 2008-03-05 2017-10-31 Council Of Scientific & Industrial Research Hybrid membrane comprising chitosan, hydroxy ethyl cellulose, and montmorillonite
EP2287323A1 (en) 2009-07-31 2011-02-23 Association Institut de Myologie Widespread gene delivery to the retina using systemic administration of AAV vectors
EP2292781A1 (en) 2009-08-17 2011-03-09 Genethon Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions
CN102884196B (zh) * 2010-04-01 2015-05-06 肖卫东 重组病毒载体的结构及其制备
KR101549296B1 (ko) 2010-04-14 2015-09-01 이엠디 밀리포어 코포레이션 고역가 고순도 바이러스 스톡의 생산 방법 및 이의 사용 방법
EP3470523A1 (en) 2012-05-09 2019-04-17 Oregon Health & Science University Adeno associated virus plasmids and vectors
TWI702955B (zh) 2012-05-15 2020-09-01 澳大利亞商艾佛蘭屈澳洲私營有限公司 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd)
JP6417322B2 (ja) 2012-06-21 2018-11-07 アソシアシオン・アンスティテュ・ドゥ・ミオロジーAssociation Institut De Myologie 遺伝子治療ベクターの広範な遺伝子送達
US11078464B2 (en) * 2013-08-30 2021-08-03 Amgen Inc. High titer recombinant AAV vector production in adherent and suspension cells
ES3042252T3 (en) 2014-03-17 2025-11-19 Adverum Biotechnologies Inc Compositions and methods for enhanced gene expression in cone cells
BR112017018846A2 (pt) 2015-03-02 2018-07-31 Adverum Biotechnologies, Inc. composições e métodos para entrega intravítrea de polinucleotídeos a cones retinianos.
GB2545763A (en) 2015-12-23 2017-06-28 Adverum Biotechnologies Inc Mutant viral capsid libraries and related systems and methods
AU2018373279B2 (en) 2017-11-27 2024-07-25 Trames Bio, Inc. Compositions and methods for neurological diseases
US10610606B2 (en) 2018-02-01 2020-04-07 Homology Medicines, Inc. Adeno-associated virus compositions for PAH gene transfer and methods of use thereof
KR20200127170A (ko) 2018-02-01 2020-11-10 호몰로지 메디슨, 인크. Pah 유전자 기능 복원을 위한 아데노-연관 바이러스 조성물 및 이의 사용 방법
EP3755795A4 (en) 2018-02-19 2022-07-20 Homology Medicines, Inc. Adeno-associated virus compositions for restoring f8 gene function and methods of use thereof
BR112020022669A2 (pt) 2018-05-08 2021-02-17 Neuracle Science Co., Ltd distribuição de vírus adenoassociado (aav) de anticorpos anti-fam19a5
WO2020160508A1 (en) 2019-01-31 2020-08-06 Oregon Health & Science University Methods for using transcription-dependent directed evolution of aav capsids
CN114746450A (zh) 2019-08-21 2022-07-12 科达生物治疗医药有限公司 用于神经学疾病的组合物和方法
TW202140791A (zh) 2020-01-13 2021-11-01 美商霍蒙拉奇醫藥公司 治療苯酮尿症之方法
TW202208632A (zh) 2020-05-27 2022-03-01 美商同源醫藥公司 用於恢復pah基因功能的腺相關病毒組成物及其使用方法
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US20230374542A1 (en) 2020-10-07 2023-11-23 Asklepios Biopharmaceutical, Inc. Therapeutic adeno-associated virus delivery of fukutin related protein (fkrp) for treating dystroglycanopathy. disorders including limb girdle 21 (lgmd21)
CN119487063A (zh) 2022-04-29 2025-02-18 博闻生物有限责任公司 双特异性抗体以及治疗眼部疾病的方法
WO2023212294A1 (en) 2022-04-29 2023-11-02 Broadwing Bio Llc Angiopoietin-related protein 7-specific antibodies and uses thereof
WO2023212293A1 (en) 2022-04-29 2023-11-02 Broadwing Bio Llc Complement factor h related 4-specific antibodies and uses thereof
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EP0785803A4 (en) * 1994-09-23 2000-08-02 Gen Hospital Corp Use of a non-mammalian dna virus to express an exogenous gene in a mammalian cell

Also Published As

Publication number Publication date
US6387670B1 (en) 2002-05-14
JP4686670B2 (ja) 2011-05-25
IL129686A0 (en) 2000-02-29
DE69735274T2 (de) 2006-10-12
HUP0001762A3 (en) 2002-01-28
CZ182299A3 (cs) 1999-08-11
SK286900B6 (sk) 2009-07-06
KR20000057202A (ko) 2000-09-15
US20030022356A1 (en) 2003-01-30
WO1998022607A1 (fr) 1998-05-28
EP0946741B1 (fr) 2006-02-15
ES2260803T3 (es) 2006-11-01
JP2001503993A (ja) 2001-03-27
NO992464L (no) 1999-06-23
AU5226198A (en) 1998-06-10
FR2756297B1 (fr) 1999-01-08
HUP0001762A2 (hu) 2000-09-28
KR100719645B1 (ko) 2007-05-17
BR9713388A (pt) 2000-03-21
ATE317908T1 (de) 2006-03-15
NO2013009I1 (no) 2013-04-29
IL129686A (en) 2005-12-18
AU731106B2 (en) 2001-03-22
HU224713B1 (en) 2006-01-30
CA2271438C (fr) 2010-10-26
BR9713388B1 (pt) 2009-01-13
EP0946741A1 (fr) 1999-10-06
CZ293947B6 (cs) 2004-08-18
SK66699A3 (en) 2000-02-14
CA2271438A1 (fr) 1998-05-28
FR2756297A1 (fr) 1998-05-29
NO992464D0 (no) 1999-05-21
ZA9710516B (en) 1998-06-10
DE69735274D1 (de) 2006-04-20

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