NO323110B1 - Preparat innbefattende en nukleinsyre og kationisk polymer samt anvendelse av polymeren. - Google Patents
Preparat innbefattende en nukleinsyre og kationisk polymer samt anvendelse av polymeren. Download PDFInfo
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- NO323110B1 NO323110B1 NO19970049A NO970049A NO323110B1 NO 323110 B1 NO323110 B1 NO 323110B1 NO 19970049 A NO19970049 A NO 19970049A NO 970049 A NO970049 A NO 970049A NO 323110 B1 NO323110 B1 NO 323110B1
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- preparation according
- nucleic acid
- polymer
- cells
- transfection
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Polyamides (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9408735A FR2722506B1 (fr) | 1994-07-13 | 1994-07-13 | Composition contenant des acides nucleiques, preparation et utilisations |
| PCT/FR1995/000914 WO1996002655A1 (fr) | 1994-07-13 | 1995-07-07 | Composition contenant des acides nucleiques, preparation et utilisations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO970049D0 NO970049D0 (no) | 1997-01-07 |
| NO970049L NO970049L (no) | 1997-01-07 |
| NO323110B1 true NO323110B1 (no) | 2007-01-02 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| NO19970049A NO323110B1 (no) | 1994-07-13 | 1997-01-07 | Preparat innbefattende en nukleinsyre og kationisk polymer samt anvendelse av polymeren. |
Country Status (18)
| Country | Link |
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| US (1) | US6013240A (xx) |
| EP (1) | EP0770140B1 (xx) |
| JP (1) | JP4275728B2 (xx) |
| KR (1) | KR100424802B1 (xx) |
| AT (1) | ATE367448T1 (xx) |
| AU (1) | AU2930795A (xx) |
| CA (1) | CA2194797C (xx) |
| DE (1) | DE69535540T9 (xx) |
| DK (1) | DK0770140T3 (xx) |
| ES (1) | ES2290952T3 (xx) |
| FI (1) | FI119738B (xx) |
| FR (1) | FR2722506B1 (xx) |
| IL (1) | IL114566A (xx) |
| MX (1) | MX9700270A (xx) |
| NO (1) | NO323110B1 (xx) |
| PT (1) | PT770140E (xx) |
| WO (1) | WO1996002655A1 (xx) |
| ZA (1) | ZA955849B (xx) |
Families Citing this family (125)
| Publication number | Priority date | Publication date | Assignee | Title |
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| FR2730637B1 (fr) | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| CA2222328C (en) * | 1995-06-07 | 2012-01-10 | Inex Pharmaceuticals Corporation | Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer |
| US7422902B1 (en) | 1995-06-07 | 2008-09-09 | The University Of British Columbia | Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer |
| FR2739292B1 (fr) * | 1995-09-28 | 1997-10-31 | Rhone Poulenc Rorer Sa | Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations |
| GB2324534B (en) * | 1996-01-06 | 2000-05-10 | Danbiosyst Uk | Composition for delivery of nucleic acid to a cell |
| DE19746362A1 (de) * | 1996-10-23 | 1998-04-30 | Sueddeutsche Kalkstickstoff | Verfahren zur Herstellung von biologisch aktiven Polymernanopartikel-Nucleinsäure-Konjugaten |
| EP0956001B1 (en) * | 1996-11-12 | 2012-09-12 | The Regents of The University of California | Preparation of stable formulations of lipid-nucleic acid complexes for efficient in vivo delivery |
| US6884430B1 (en) * | 1997-02-10 | 2005-04-26 | Aventis Pharma S.A. | Formulation of stabilized cationic transfection agent(s) /nucleic acid particles |
| WO1998040510A1 (en) | 1997-03-11 | 1998-09-17 | Regents Of The University Of Minnesota | Dna-based transposon system for the introduction of nucleic acid into dna of a cell |
| US5912225A (en) | 1997-04-14 | 1999-06-15 | Johns Hopkins Univ. School Of Medicine | Biodegradable poly (phosphoester-co-desaminotyrosyl L-tyrosine ester) compounds, compositions, articles and methods for making and using the same |
| US6524613B1 (en) | 1997-04-30 | 2003-02-25 | Regents Of The University Of Minnesota | Hepatocellular chimeraplasty |
| DE19726186A1 (de) * | 1997-06-20 | 1998-12-24 | Boehringer Ingelheim Int | Komplexe für den Transport von Nukleinsäure in höhere eukaryotische Zellen |
| US20020022034A1 (en) * | 1997-09-15 | 2002-02-21 | Julianna Lisziewicz | Therapeutic DNA vaccination |
| EP1024836B1 (en) | 1997-09-15 | 2006-12-13 | Genetic Immunity, LLC | Compositions for delivering genes to antigen presenting cells of the skin |
| DE19743135A1 (de) * | 1997-09-30 | 1999-04-01 | Hoechst Marion Roussel De Gmbh | Biologisch verträgliche niedermolekular Polyethylenimine |
| EP1096957A1 (en) | 1998-06-18 | 2001-05-09 | Johns Hopkins University School of Medicine | Methods and reagents for intramuscular delivery of nucleic acids |
| US6916490B1 (en) | 1998-07-23 | 2005-07-12 | UAB Research Center | Controlled release of bioactive substances |
| US6562371B1 (en) * | 1998-11-02 | 2003-05-13 | Terumo Kabushiki Kaisha | Liposomes |
| US7160682B2 (en) * | 1998-11-13 | 2007-01-09 | Regents Of The University Of Minnesota | Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell |
| CA2368185A1 (en) * | 1999-04-02 | 2000-10-12 | Research Development Foundation | Polyethyleneimine:dna formulations for aerosol delivery |
| US6770740B1 (en) | 1999-07-13 | 2004-08-03 | The Regents Of The University Of Michigan | Crosslinked DNA condensate compositions and gene delivery methods |
| FR2797402B1 (fr) | 1999-07-15 | 2004-03-12 | Biomerieux Stelhys | Utilisation d'un polypeptide pour detecter, prevenir ou traiter un etat pathologique associe a une maladie degenerative, neurologique ou autoimmune |
| DE19960206A1 (de) * | 1999-12-14 | 2001-07-19 | Frank Czubayko | Komplexierung von RNS mit Polyethyleniminen zur deren Stabilisierung und zellulären Einschleusung |
| AU782912B2 (en) | 1999-12-28 | 2005-09-08 | Association Francaise Contre Les Myopathies | Use of lithium (Li+) for the preparation of a composition for transfection of a polynucleotide into a cell and compositions useful in gene therapy |
| EP1242609A2 (en) * | 1999-12-30 | 2002-09-25 | Novartis AG | Novel colloid synthetic vectors for gene therapy |
| FR2805271B1 (fr) * | 2000-02-18 | 2002-04-26 | Aventis Pharma Sa | Procede de preparation de polyalkylenimines fonctionnalises, compositions les contenant et leurs utilisations |
| ATE312088T1 (de) * | 2000-09-05 | 2005-12-15 | Centelion | Säureempfindliche verbindungen, deren herstellung und verwendungen |
| FR2813605B1 (fr) * | 2000-09-05 | 2002-10-18 | Aventis Pharma Sa | Composes acidosensibles, leur preparation et utilisations |
| FR2814370B1 (fr) * | 2000-09-22 | 2004-08-20 | Centre Nat Rech Scient | Utilisation d'un complexe acide nucleique/pei pour le ciblage de cellules souches du cerveau |
| CA2424967A1 (en) * | 2000-10-09 | 2003-04-04 | Bayer Aktiengesellschaft | Complexes for transferring nucleic acids into cells |
| DE10145134A1 (de) * | 2000-10-09 | 2002-05-16 | Bayer Ag | Komplexe zur Einführung von Nukleinsäuren in Zellen |
| US20020091242A1 (en) | 2000-10-11 | 2002-07-11 | Michel Bessodes | Acid-sensitive compounds, their preparation and uses |
| JP2004537501A (ja) * | 2001-02-01 | 2004-12-16 | ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム | 肺への遺伝子送達のための安定化ポリマーエアロゾル |
| US6652886B2 (en) | 2001-02-16 | 2003-11-25 | Expression Genetics | Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents |
| WO2002100435A1 (en) * | 2001-06-11 | 2002-12-19 | Centre Hospitalier Universitaire De Montreal | Compositions and methods for enhancing nucleic acid transfer into cells |
| ATE447967T1 (de) | 2001-09-14 | 2009-11-15 | Cytos Biotechnology Ag | Verpackung von immunstimulierendem cpg in virusähnlichen partikeln: herstellungsverfahren und verwendung |
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| US8227432B2 (en) * | 2002-04-22 | 2012-07-24 | Regents Of The University Of Minnesota | Transposon system and methods of use |
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-
1994
- 1994-07-13 FR FR9408735A patent/FR2722506B1/fr not_active Expired - Lifetime
-
1995
- 1995-07-07 JP JP50474196A patent/JP4275728B2/ja not_active Expired - Lifetime
- 1995-07-07 PT PT95925026T patent/PT770140E/pt unknown
- 1995-07-07 AT AT95925026T patent/ATE367448T1/de active
- 1995-07-07 MX MX9700270A patent/MX9700270A/es unknown
- 1995-07-07 AU AU29307/95A patent/AU2930795A/en not_active Abandoned
- 1995-07-07 CA CA2194797A patent/CA2194797C/fr not_active Expired - Lifetime
- 1995-07-07 ES ES95925026T patent/ES2290952T3/es not_active Expired - Lifetime
- 1995-07-07 US US08/765,679 patent/US6013240A/en not_active Expired - Lifetime
- 1995-07-07 WO PCT/FR1995/000914 patent/WO1996002655A1/fr active IP Right Grant
- 1995-07-07 KR KR1019970700200A patent/KR100424802B1/ko not_active IP Right Cessation
- 1995-07-07 DE DE69535540T patent/DE69535540T9/de active Active
- 1995-07-07 DK DK95925026T patent/DK0770140T3/da active
- 1995-07-07 EP EP95925026A patent/EP0770140B1/fr not_active Expired - Lifetime
- 1995-07-12 IL IL11456695A patent/IL114566A/xx not_active IP Right Cessation
- 1995-07-13 ZA ZA955849A patent/ZA955849B/xx unknown
-
1997
- 1997-01-07 NO NO19970049A patent/NO323110B1/no not_active IP Right Cessation
- 1997-01-10 FI FI970115A patent/FI119738B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69535540T2 (de) | 2008-06-19 |
| JP4275728B2 (ja) | 2009-06-10 |
| ZA955849B (en) | 1996-02-21 |
| ES2290952T3 (es) | 2008-02-16 |
| WO1996002655A1 (fr) | 1996-02-01 |
| NO970049D0 (no) | 1997-01-07 |
| DK0770140T3 (da) | 2007-11-19 |
| KR970704889A (ko) | 1997-09-06 |
| PT770140E (pt) | 2007-10-19 |
| ATE367448T1 (de) | 2007-08-15 |
| IL114566A (en) | 2005-08-31 |
| MX9700270A (es) | 1997-05-31 |
| DE69535540D1 (de) | 2007-08-30 |
| JPH10502918A (ja) | 1998-03-17 |
| FR2722506A1 (fr) | 1996-01-19 |
| FR2722506B1 (fr) | 1996-08-14 |
| CA2194797A1 (fr) | 1996-02-01 |
| EP0770140A1 (fr) | 1997-05-02 |
| AU2930795A (en) | 1996-02-16 |
| FI970115A (fi) | 1997-01-10 |
| IL114566A0 (en) | 1995-11-27 |
| NO970049L (no) | 1997-01-07 |
| DE69535540T9 (de) | 2012-03-15 |
| CA2194797C (fr) | 2010-03-23 |
| FI119738B (fi) | 2009-02-27 |
| KR100424802B1 (ko) | 2004-06-23 |
| EP0770140B1 (fr) | 2007-07-18 |
| US6013240A (en) | 2000-01-11 |
| FI970115A0 (fi) | 1997-01-10 |
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