NO317625B1 - Ligand til CD40 reseptoren, DNA, Vektor, Vertcelle, Fremgangsmate for fremstilling, Protein og Farmasoytisk preparat. - Google Patents
Ligand til CD40 reseptoren, DNA, Vektor, Vertcelle, Fremgangsmate for fremstilling, Protein og Farmasoytisk preparat. Download PDFInfo
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- NO317625B1 NO317625B1 NO19941422A NO941422A NO317625B1 NO 317625 B1 NO317625 B1 NO 317625B1 NO 19941422 A NO19941422 A NO 19941422A NO 941422 A NO941422 A NO 941422A NO 317625 B1 NO317625 B1 NO 317625B1
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Classifications
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78370791A | 1991-10-25 | 1991-10-25 | |
US80572391A | 1991-12-05 | 1991-12-05 | |
PCT/US1992/008990 WO1993008207A1 (en) | 1991-10-25 | 1992-10-23 | Novel cytokine |
Publications (3)
Publication Number | Publication Date |
---|---|
NO941422D0 NO941422D0 (no) | 1994-04-19 |
NO941422L NO941422L (de) | 1994-06-27 |
NO317625B1 true NO317625B1 (no) | 2004-11-29 |
Family
ID=27120174
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19941422A NO317625B1 (no) | 1991-10-25 | 1994-04-19 | Ligand til CD40 reseptoren, DNA, Vektor, Vertcelle, Fremgangsmate for fremstilling, Protein og Farmasoytisk preparat. |
NO19980030A NO320073B1 (no) | 1991-10-25 | 1998-01-05 | Antistoffer som binder CD40-L |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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NO19980030A NO320073B1 (no) | 1991-10-25 | 1998-01-05 | Antistoffer som binder CD40-L |
Country Status (13)
Country | Link |
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EP (2) | EP0897983B1 (de) |
JP (2) | JP3308534B2 (de) |
KR (1) | KR100283541B1 (de) |
AT (2) | ATE274055T1 (de) |
AU (1) | AU661360B2 (de) |
CA (2) | CA2121798C (de) |
DE (2) | DE69233402T3 (de) |
DK (3) | DK0667901T4 (de) |
ES (2) | ES2227513T5 (de) |
FI (2) | FI116850B (de) |
HK (1) | HK1019343A1 (de) |
NO (2) | NO317625B1 (de) |
WO (1) | WO1993008207A1 (de) |
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US5474771A (en) | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
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AU1059095A (en) * | 1993-11-24 | 1995-06-13 | Australian National University, The | Treatment of viral disease with cd40l peptide |
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US5683693A (en) * | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
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ATE220331T1 (de) * | 1995-03-01 | 2002-07-15 | Immunex Corp | Cd40 bindendes protein zur stimulierung der immunantwort |
WO1996028568A1 (en) | 1995-03-13 | 1996-09-19 | The Regents Of The University Of Michigan | Cd40 binding compositions and methods of using same |
ATE257858T1 (de) * | 1995-06-07 | 2004-01-15 | Immunex Corp | Cd40l mutein |
DK0833847T3 (da) * | 1995-06-22 | 2003-12-29 | Biogen Inc | Krystaller af fregmenter af CD40-ligand og deres anvendelse |
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US6340459B1 (en) | 1995-12-01 | 2002-01-22 | The Trustees Of Columbia University In The City Of New York | Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients |
AU3570797A (en) * | 1996-06-14 | 1998-01-07 | University Of Washington | Absorption-enhanced differential extraction device |
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KR20000022445A (ko) * | 1996-07-10 | 2000-04-25 | 크리스토퍼 엘. 와이트, 스코트 지. 홀퀴스트, 스티븐 엘. 말라스카 | 수상돌기 세포의 활성화 방법 |
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US7300774B1 (en) | 1999-12-09 | 2007-11-27 | The Regents Of The University Of California | Multimeric fusion proteins of the TNF superfamily ligands |
EP1067194A1 (de) * | 1999-04-16 | 2001-01-10 | F. Hoffmann-La Roche Ag | Vektoren, die Gene enthalten, die für CD40 und/oder CD40L kodieren die unter der Kontrolle von einer Cytokin-induzierbaren Promotorsequenz sind. Dieser Promotor stammt von einem menschlischen akutphasen-Serumamyloid-A-Gen. Verfahren zur Herstellung derselben und Verwendung davon |
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WO2001016180A2 (en) * | 1999-08-27 | 2001-03-08 | Board Of Regents, The University Of Texas System | Cd40 agonist compositions and methods of use |
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CA2089229C (en) * | 1992-02-14 | 2010-04-13 | Alejandro A. Aruffo | Cd40cr receptor and ligands therefor |
US5540926A (en) * | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
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1992
- 1992-10-23 DE DE69233402T patent/DE69233402T3/de not_active Expired - Fee Related
- 1992-10-23 EP EP98113461A patent/EP0897983B1/de not_active Revoked
- 1992-10-23 DK DK92925017T patent/DK0667901T4/da active
- 1992-10-23 AU AU31226/93A patent/AU661360B2/en not_active Expired
- 1992-10-23 ES ES92925017T patent/ES2227513T5/es not_active Expired - Lifetime
- 1992-10-23 WO PCT/US1992/008990 patent/WO1993008207A1/en active IP Right Grant
- 1992-10-23 ES ES98113461T patent/ES2198025T3/es not_active Expired - Lifetime
- 1992-10-23 CA CA002121798A patent/CA2121798C/en not_active Expired - Fee Related
- 1992-10-23 AT AT92925017T patent/ATE274055T1/de not_active IP Right Cessation
- 1992-10-23 CA CA002312667A patent/CA2312667C/en not_active Expired - Lifetime
- 1992-10-23 KR KR1019940701285A patent/KR100283541B1/ko not_active IP Right Cessation
- 1992-10-23 JP JP50789793A patent/JP3308534B2/ja not_active Expired - Fee Related
- 1992-10-23 DE DE69233051T patent/DE69233051T2/de not_active Revoked
- 1992-10-23 DK DK97117514T patent/DK0822199T3/da active
- 1992-10-23 AT AT98113461T patent/ATE239790T1/de not_active IP Right Cessation
- 1992-10-23 DK DK98113461T patent/DK0897983T3/da active
- 1992-10-23 EP EP92925017A patent/EP0667901B2/de not_active Expired - Lifetime
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1994
- 1994-04-19 NO NO19941422A patent/NO317625B1/no not_active IP Right Cessation
- 1994-04-20 FI FI941837A patent/FI116850B/fi active IP Right Grant
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1997
- 1997-11-19 JP JP9318110A patent/JP2877788B2/ja not_active Expired - Lifetime
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1998
- 1998-01-05 NO NO19980030A patent/NO320073B1/no not_active IP Right Cessation
- 1998-08-17 FI FI981765A patent/FI116828B/fi not_active IP Right Cessation
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1999
- 1999-08-24 HK HK99103655A patent/HK1019343A1/xx not_active IP Right Cessation
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