NO317049B1 - Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein - Google Patents

Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein Download PDF

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Publication number
NO317049B1
NO317049B1 NO19943755A NO943755A NO317049B1 NO 317049 B1 NO317049 B1 NO 317049B1 NO 19943755 A NO19943755 A NO 19943755A NO 943755 A NO943755 A NO 943755A NO 317049 B1 NO317049 B1 NO 317049B1
Authority
NO
Norway
Prior art keywords
mbp
cells
cell
peptide
antigen
Prior art date
Application number
NO19943755A
Other languages
English (en)
Norwegian (no)
Other versions
NO943755L (no
NO943755D0 (no
Inventor
David A Hafler
Howard L Weiner
Ariel Miller
Ahmad Al-Sabbagh
Original Assignee
Autoimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Autoimmune Inc filed Critical Autoimmune Inc
Publication of NO943755D0 publication Critical patent/NO943755D0/no
Publication of NO943755L publication Critical patent/NO943755L/no
Publication of NO317049B1 publication Critical patent/NO317049B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Rehabilitation Therapy (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19943755A 1992-04-09 1994-10-06 Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein NO317049B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86531892A 1992-04-09 1992-04-09
PCT/US1993/003369 WO1993021222A1 (en) 1992-04-09 1993-04-09 Suppression of t-cell proliferation using peptide fragments of myelin basic protein

Publications (3)

Publication Number Publication Date
NO943755D0 NO943755D0 (no) 1994-10-06
NO943755L NO943755L (no) 1994-12-02
NO317049B1 true NO317049B1 (no) 2004-07-26

Family

ID=25345228

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19943755A NO317049B1 (no) 1992-04-09 1994-10-06 Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein

Country Status (15)

Country Link
EP (2) EP0863155B1 (enExample)
JP (1) JP3434510B2 (enExample)
KR (1) KR950700934A (enExample)
AT (2) ATE212358T1 (enExample)
AU (1) AU680824B2 (enExample)
BR (1) BR9306272A (enExample)
CA (1) CA2133749A1 (enExample)
DE (2) DE69331501T2 (enExample)
DK (1) DK0863155T3 (enExample)
ES (1) ES2172044T3 (enExample)
HU (1) HU219306B (enExample)
IL (1) IL105347A0 (enExample)
NO (1) NO317049B1 (enExample)
PT (1) PT863155E (enExample)
WO (1) WO1993021222A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869054A (en) * 1987-06-24 1999-02-09 Autoimmune Inc. Treatment of multiple sclerosis by oral administration of autoantigens
US5817629A (en) * 1991-10-22 1998-10-06 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US6252040B1 (en) 1991-10-22 2001-06-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
HUT76099A (en) * 1994-05-10 1997-06-30 Immulogic Pharma Corp Compositions and treatment for multiple sclerosis
PL324091A1 (en) * 1994-10-25 1998-05-11 Immulogic Pharma Corp Compositions and procedure for treating sclerosis multiplex
US6251396B1 (en) 1994-11-18 2001-06-26 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6329499B1 (en) * 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein
JPH10509714A (ja) 1994-11-18 1998-09-22 ニューロクライン バイオサイエンシーズ, インコーポレイテッド ヒトミエリン塩基性タンパク質の91位におけるペプチドアナログを用いる多発性硬化症の処置方法
US6379670B1 (en) 1994-11-18 2002-04-30 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
WO1996028470A2 (en) * 1995-03-09 1996-09-19 Neurocrine Biosciences, Inc. Peptide analogues of human myelin basic protein useful in treating multiple sclerosis
US5856446A (en) * 1995-07-07 1999-01-05 Autoimmune Inc. Method of treating rheumatoid arthritis with low dose type II collagen
IL116559A (en) * 1995-11-17 2005-11-20 Yissum Res Dev Co Chimeric protein consisting of a bacterial toxin and a myelin basic protein sequence
US6274136B1 (en) * 1996-05-29 2001-08-14 University Of Southern California Construction and use of genes encoding pathogenic epitopes for treatment of autoimmune disease
CA2201841C (en) * 1997-04-04 2010-01-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US20020072493A1 (en) 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
EP1080110A2 (en) * 1998-05-19 2001-03-07 Yeda Research And Development Co. Ltd. Use of activated t cells, nervous system-specific antigens for treating disorders of the nevrous system
US7261896B2 (en) 2000-05-24 2007-08-28 United States Of America As Represented By The Secretary Of The Department Of Health And Human Services National Institutes Of Health Methods for preventing strokes by inducing tolerance to e-selectin
US20080107664A1 (en) 2003-10-17 2008-05-08 Zang Ying C Q Method For Increasing Cd8+ Cytotoxic T Cell Responses And For Treating Multiple Sclerosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995008572A1 (en) * 1993-09-22 1995-03-30 The Board Of Trustees For The Leland Stanford Junior University Interaction of t-cell receptors and antigen in autoimmune disease
JPH10509714A (ja) * 1994-11-18 1998-09-22 ニューロクライン バイオサイエンシーズ, インコーポレイテッド ヒトミエリン塩基性タンパク質の91位におけるペプチドアナログを用いる多発性硬化症の処置方法

Also Published As

Publication number Publication date
ATE212358T1 (de) 2002-02-15
KR950700934A (ko) 1995-02-20
ATE170874T1 (de) 1998-09-15
JP3434510B2 (ja) 2003-08-11
WO1993021222A1 (en) 1993-10-28
DE69331501D1 (de) 2002-03-14
DE69320967D1 (de) 1998-10-15
HUT69169A (en) 1995-08-28
DE69320967T2 (de) 1999-05-12
KR100295606B1 (enExample) 2001-10-22
DE69331501T2 (de) 2002-08-29
BR9306272A (pt) 1998-06-23
CA2133749A1 (en) 1993-10-28
EP0650498B1 (en) 1998-09-09
HU219306B (en) 2001-03-28
AU4282493A (en) 1993-11-18
EP0650498A1 (en) 1995-05-03
IL105347A0 (en) 1993-08-18
PT863155E (pt) 2002-07-31
NO943755L (no) 1994-12-02
DK0863155T3 (da) 2002-05-13
AU680824B2 (en) 1997-08-14
EP0650498A4 (en) 1995-06-21
NO943755D0 (no) 1994-10-06
EP0863155A1 (en) 1998-09-09
HU9402909D0 (en) 1995-01-30
ES2172044T3 (es) 2002-09-16
JPH08500083A (ja) 1996-01-09
EP0863155B1 (en) 2002-01-23

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