NO943755D0 - Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein - Google Patents

Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein

Info

Publication number
NO943755D0
NO943755D0 NO943755A NO943755A NO943755D0 NO 943755 D0 NO943755 D0 NO 943755D0 NO 943755 A NO943755 A NO 943755A NO 943755 A NO943755 A NO 943755A NO 943755 D0 NO943755 D0 NO 943755D0
Authority
NO
Norway
Prior art keywords
fragments
suppression
cell proliferation
basic protein
myelin basic
Prior art date
Application number
NO943755A
Other languages
English (en)
Other versions
NO943755L (no
NO317049B1 (no
Inventor
Howard L Weiner
David A Hafler
Ariel Miller
Ahmad Al-Sabbagh
Original Assignee
Autoimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Autoimmune Inc filed Critical Autoimmune Inc
Publication of NO943755D0 publication Critical patent/NO943755D0/no
Publication of NO943755L publication Critical patent/NO943755L/no
Publication of NO317049B1 publication Critical patent/NO317049B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Rehabilitation Therapy (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19943755A 1992-04-09 1994-10-06 Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein NO317049B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86531892A 1992-04-09 1992-04-09
PCT/US1993/003369 WO1993021222A1 (en) 1992-04-09 1993-04-09 Suppression of t-cell proliferation using peptide fragments of myelin basic protein

Publications (3)

Publication Number Publication Date
NO943755D0 true NO943755D0 (no) 1994-10-06
NO943755L NO943755L (no) 1994-12-02
NO317049B1 NO317049B1 (no) 2004-07-26

Family

ID=25345228

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19943755A NO317049B1 (no) 1992-04-09 1994-10-06 Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein

Country Status (15)

Country Link
EP (2) EP0650498B1 (no)
JP (1) JP3434510B2 (no)
KR (1) KR950700934A (no)
AT (2) ATE170874T1 (no)
AU (1) AU680824B2 (no)
BR (1) BR9306272A (no)
CA (1) CA2133749A1 (no)
DE (2) DE69331501T2 (no)
DK (1) DK0863155T3 (no)
ES (1) ES2172044T3 (no)
HU (1) HU219306B (no)
IL (1) IL105347A0 (no)
NO (1) NO317049B1 (no)
PT (1) PT863155E (no)
WO (1) WO1993021222A1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869054A (en) * 1987-06-24 1999-02-09 Autoimmune Inc. Treatment of multiple sclerosis by oral administration of autoantigens
US6252040B1 (en) 1991-10-22 2001-06-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US5817629A (en) * 1991-10-22 1998-10-06 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
SK145896A3 (en) * 1994-05-10 1997-05-07 Immulogic Pharma Corp Medicaments containing therapeutically effective quantity of antigen peptid of human mbp and ifn-beta
WO1996012737A2 (en) * 1994-10-25 1996-05-02 Immulogic Pharmaceutical Corporation Compositions and treatment for multiple sclerosis
US6329499B1 (en) * 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein
US6251396B1 (en) 1994-11-18 2001-06-26 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
EP1172376A1 (en) * 1994-11-18 2002-01-16 Neurocrine Biosciences, Inc. Peptide analogues at position 91 of human myelin basic protein for treatment of multiple sclerosis
US6379670B1 (en) 1994-11-18 2002-04-30 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
AU5360796A (en) * 1995-03-09 1996-10-02 Neurocrine Biosciences, Inc. Peptide analogues of human myelin basic protein useful in treating multiple sclerosis
US5856446A (en) * 1995-07-07 1999-01-05 Autoimmune Inc. Method of treating rheumatoid arthritis with low dose type II collagen
IL116559A (en) * 1995-11-17 2005-11-20 Yissum Res Dev Co Chimeric protein consisting of a bacterial toxin and a myelin basic protein sequence
US6274136B1 (en) * 1996-05-29 2001-08-14 University Of Southern California Construction and use of genes encoding pathogenic epitopes for treatment of autoimmune disease
CA2494338C (en) * 1997-04-04 2007-07-17 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US20020072493A1 (en) 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
WO1999060021A2 (en) * 1998-05-19 1999-11-25 Yeda Research And Development Co. Ltd. Use of activated t cells, nervous system-specific antigens for treating disorders of the nevrous system
JP4986361B2 (ja) 2000-05-24 2012-07-25 ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ E−セレクチンに対する寛容誘導による脳卒中防止法
BRPI0415519A (pt) 2003-10-17 2006-12-26 Baylor College Medicine método para aumento das respostas de célula t citotóxica cd8+ e para tratamento de esclerose múltipla

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU695801B2 (en) * 1993-09-22 1998-08-20 Board Of Trustees Of The Leland Stanford Junior University Interaction of T-cell receptors and antigen in autoimmune disease
EP1172376A1 (en) * 1994-11-18 2002-01-16 Neurocrine Biosciences, Inc. Peptide analogues at position 91 of human myelin basic protein for treatment of multiple sclerosis

Also Published As

Publication number Publication date
DE69331501T2 (de) 2002-08-29
EP0650498A1 (en) 1995-05-03
AU4282493A (en) 1993-11-18
DE69320967D1 (de) 1998-10-15
DE69320967T2 (de) 1999-05-12
ATE212358T1 (de) 2002-02-15
EP0650498A4 (en) 1995-06-21
DK0863155T3 (da) 2002-05-13
HUT69169A (en) 1995-08-28
EP0650498B1 (en) 1998-09-09
BR9306272A (pt) 1998-06-23
DE69331501D1 (de) 2002-03-14
IL105347A0 (en) 1993-08-18
WO1993021222A1 (en) 1993-10-28
KR100295606B1 (no) 2001-10-22
ATE170874T1 (de) 1998-09-15
EP0863155A1 (en) 1998-09-09
PT863155E (pt) 2002-07-31
EP0863155B1 (en) 2002-01-23
HU219306B (en) 2001-03-28
ES2172044T3 (es) 2002-09-16
JP3434510B2 (ja) 2003-08-11
HU9402909D0 (en) 1995-01-30
NO943755L (no) 1994-12-02
AU680824B2 (en) 1997-08-14
NO317049B1 (no) 2004-07-26
KR950700934A (ko) 1995-02-20
JPH08500083A (ja) 1996-01-09
CA2133749A1 (en) 1993-10-28

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