DE69831754D1 - Zelloberflächenglycoproteinen zusammenhang mit menschlicher b zell lymphomen - ulbp, dns und polypeptiden - Google Patents

Zelloberflächenglycoproteinen zusammenhang mit menschlicher b zell lymphomen - ulbp, dns und polypeptiden

Info

Publication number
DE69831754D1
DE69831754D1 DE69831754T DE69831754T DE69831754D1 DE 69831754 D1 DE69831754 D1 DE 69831754D1 DE 69831754 T DE69831754 T DE 69831754T DE 69831754 T DE69831754 T DE 69831754T DE 69831754 D1 DE69831754 D1 DE 69831754D1
Authority
DE
Germany
Prior art keywords
polypeptides
ulbp
cell
isolated
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831754T
Other languages
English (en)
Other versions
DE69831754T2 (de
Inventor
John Cosman
H Mullberg
Cristian Fanslow
Marek Kubin
Richard J Armitage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of DE69831754D1 publication Critical patent/DE69831754D1/de
Application granted granted Critical
Publication of DE69831754T2 publication Critical patent/DE69831754T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69831754T 1997-12-17 1998-12-17 Zelloberflächenglycoproteinen zusammenhang mit menschlicher b zell lymphomen - ulbp, dns und polypeptiden Expired - Lifetime DE69831754T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6985797P 1997-12-17 1997-12-17
US69857P 1997-12-17
US9294698P 1998-07-15 1998-07-15
US92946P 1998-07-15
PCT/US1998/027048 WO1999031241A1 (en) 1997-12-17 1998-12-17 Cell surface glycoproteins associated with human b cell lymphomas - ulbp, dna and polypeptides

Publications (2)

Publication Number Publication Date
DE69831754D1 true DE69831754D1 (de) 2006-02-09
DE69831754T2 DE69831754T2 (de) 2006-06-29

Family

ID=26750491

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831754T Expired - Lifetime DE69831754T2 (de) 1997-12-17 1998-12-17 Zelloberflächenglycoproteinen zusammenhang mit menschlicher b zell lymphomen - ulbp, dns und polypeptiden

Country Status (12)

Country Link
US (7) US6653447B1 (de)
EP (1) EP1037991B1 (de)
JP (1) JP4255211B2 (de)
AT (1) ATE305510T1 (de)
AU (1) AU742757C (de)
CA (1) CA2315251A1 (de)
DE (1) DE69831754T2 (de)
DK (1) DK1037991T3 (de)
ES (1) ES2251120T3 (de)
IL (2) IL136621A0 (de)
NZ (1) NZ505500A (de)
WO (1) WO1999031241A1 (de)

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US9809654B2 (en) 2002-09-27 2017-11-07 Vaccinex, Inc. Targeted CD1d molecules
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US7998481B2 (en) * 2004-04-05 2011-08-16 The Regents Of The University Of California Modulation of NKG2D for treating or preventing solid organ allograft rejection
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WO2011130749A2 (en) 2010-04-16 2011-10-20 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Identification of mutations in herpes simplex virus envelope glycoproteins that enable or enhance vector retargeting to novel non-hsv receptors
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WO2013036799A2 (en) * 2011-09-09 2013-03-14 Fred Hutchinson Cancer Research Center Methods and compositions involving nkg2d inhibitors and cancer
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US9371352B2 (en) 2013-02-08 2016-06-21 Vaccinex, Inc. Modified glycolipids and methods of making and using the same
WO2014144817A2 (en) 2013-03-15 2014-09-18 Amgen Inc. Inhibitory polypeptides specific to wnt inhibitors
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EP3712166A1 (de) 2013-09-05 2020-09-23 Amgen Inc. Fc-haltige moleküle mit vorhersagbaren, konsistenten und reproduzierbaren glycoformprofilen
DK3184641T3 (da) 2013-10-28 2020-08-03 Univ Of Pittsburgh - Of The Commonwealth System Of Higher Education Onkolytisk hsv-vektor
WO2015108907A2 (en) 2014-01-14 2015-07-23 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment, prevention, and treatment of melanoma using pd-l1 isoforms
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US11117969B2 (en) * 2014-12-05 2021-09-14 Xyphos Biosciences Inc. Insertable variable fragments of antibodies and modified α1-α2 domains of NKG2D ligands
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AU2018235928B2 (en) 2017-03-14 2023-09-21 Amgen Inc. Control of total afucosylated glycoforms of antibodies produced in cell culture
MX2020000993A (es) 2017-07-26 2020-07-22 Oncorus Inc Vectores virales oncolíticos y usos de estos.
WO2019133847A1 (en) 2017-12-29 2019-07-04 Oncorus, Inc. Oncolytic viral delivery of therapeutic polypeptides
US12325737B2 (en) 2018-03-26 2025-06-10 Amgen Inc. Total afucosylated glycoforms of antibodies produced in cell culture
MA52206A (fr) 2018-03-27 2021-02-17 Xyphos Biosciences Inc Domaines a1-a2 modifiés de ligands nkg2d non naturels se liant à des récepteurs nkg2d non naturels
WO2020051013A2 (en) * 2018-08-24 2020-03-12 The Trustees Of Columbia University In The City Of New York Anti-cd33 and nkg2d ligand chimeras for treatment of myeloid malignancies
KR20220069982A (ko) 2019-09-26 2022-05-27 암젠 인크 항체 조성물의 생산 방법
EP4045515A4 (de) 2019-10-18 2023-10-18 The Regents Of The University Of Michigan Biomaterialsensorsysteme
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Also Published As

Publication number Publication date
US6458350B1 (en) 2002-10-01
DE69831754T2 (de) 2006-06-29
US7193058B2 (en) 2007-03-20
CA2315251A1 (en) 1999-06-24
US20110281789A1 (en) 2011-11-17
US7427669B2 (en) 2008-09-23
JP2002508183A (ja) 2002-03-19
WO1999031241A1 (en) 1999-06-24
US6774224B2 (en) 2004-08-10
IL136621A0 (en) 2001-06-14
AU742757B2 (en) 2002-01-10
IL136621A (en) 2008-07-08
US20030147847A1 (en) 2003-08-07
EP1037991A1 (de) 2000-09-27
EP1037991B1 (de) 2005-09-28
US8410252B2 (en) 2013-04-02
DK1037991T3 (da) 2006-01-09
US20080008715A1 (en) 2008-01-10
ATE305510T1 (de) 2005-10-15
US20090324597A1 (en) 2009-12-31
NZ505500A (en) 2002-12-20
US7807796B2 (en) 2010-10-05
US6653447B1 (en) 2003-11-25
JP4255211B2 (ja) 2009-04-15
AU742757C (en) 2007-05-17
AU2004599A (en) 1999-07-05
US20040235058A1 (en) 2004-11-25
ES2251120T3 (es) 2006-04-16

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