DK1037991T3 - Celleoverfladeglycoproteiner associeret med humane B-cellelumfoner - ULBP, DNA og polypeptider - Google Patents
Celleoverfladeglycoproteiner associeret med humane B-cellelumfoner - ULBP, DNA og polypeptiderInfo
- Publication number
- DK1037991T3 DK1037991T3 DK98964802T DK98964802T DK1037991T3 DK 1037991 T3 DK1037991 T3 DK 1037991T3 DK 98964802 T DK98964802 T DK 98964802T DK 98964802 T DK98964802 T DK 98964802T DK 1037991 T3 DK1037991 T3 DK 1037991T3
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptides
- ulbp
- cell
- isolated
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6985797P | 1997-12-17 | 1997-12-17 | |
US9294698P | 1998-07-15 | 1998-07-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1037991T3 true DK1037991T3 (da) | 2006-01-09 |
Family
ID=26750491
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98964802T DK1037991T3 (da) | 1997-12-17 | 1998-12-17 | Celleoverfladeglycoproteiner associeret med humane B-cellelumfoner - ULBP, DNA og polypeptider |
Country Status (12)
Country | Link |
---|---|
US (7) | US6653447B1 (da) |
EP (1) | EP1037991B1 (da) |
JP (1) | JP4255211B2 (da) |
AT (1) | ATE305510T1 (da) |
AU (1) | AU742757C (da) |
CA (1) | CA2315251A1 (da) |
DE (1) | DE69831754T2 (da) |
DK (1) | DK1037991T3 (da) |
ES (1) | ES2251120T3 (da) |
IL (2) | IL136621A0 (da) |
NZ (1) | NZ505500A (da) |
WO (1) | WO1999031241A1 (da) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
ID30211A (id) * | 1999-03-15 | 2001-11-15 | Takeda Chemical Industries Ltd | Protein baru dan penggunaannya |
WO2002062997A1 (fr) * | 2001-02-05 | 2002-08-15 | Takeda Chemical Industries, Ltd. | Nouvelle proteine et son utilisation |
US6821522B2 (en) * | 2001-05-31 | 2004-11-23 | The Regents Of The University Of California | Tumor Therapy |
US7364890B2 (en) | 2001-07-28 | 2008-04-29 | Midwest Research Institute | Thermal tolerant avicelase from Acidothermus cellulolyticus |
MXPA04003057A (es) * | 2001-10-04 | 2005-06-20 | Immunex Corp | Proteina 4 de enlace ul16. |
CA2483343A1 (en) * | 2002-04-22 | 2003-10-30 | Fred Hutchinson Cancer Research Center | Soluble mic polypeptides as markers for diagnosis, prognosis and treatment of cancer and autoimmune diseases or conditions |
WO2004022706A2 (en) * | 2002-09-04 | 2004-03-18 | The Trustees Of The University Of Pennsylvania | Immune cell receptor ligand and immune cell receptor |
US9809654B2 (en) | 2002-09-27 | 2017-11-07 | Vaccinex, Inc. | Targeted CD1d molecules |
EP1413316A1 (en) * | 2002-09-27 | 2004-04-28 | Bruno Robert | Bifunctional conjugates or fusion proteins |
MXPA05010255A (es) * | 2003-03-24 | 2005-12-14 | Scripps Research Inst | Vacunas de adn contra crecimiento tumoral y metodos de uso de las mismas. |
US7666417B2 (en) * | 2003-04-22 | 2010-02-23 | Fred Hutchinson Cancer Research Center | Methods and compositions for treating autoimmune diseases or conditions |
GB0403491D0 (en) * | 2004-02-17 | 2004-03-24 | Univ Cambridge Tech | Polypeptides, methods and means |
US7998481B2 (en) * | 2004-04-05 | 2011-08-16 | The Regents Of The University Of California | Modulation of NKG2D for treating or preventing solid organ allograft rejection |
AU2005231478C1 (en) * | 2004-04-05 | 2009-04-09 | The Regents Of The University Of California | Modulation of NKG2D |
US9249464B2 (en) | 2004-11-29 | 2016-02-02 | Sequenom, Inc. | Kits and methods for detecting methylated DNA |
CA2589487C (en) | 2004-11-29 | 2014-07-29 | Klinikum Der Universitat Regensburg | Means and methods for detecting methylated dna |
EP1909832A4 (en) * | 2005-06-29 | 2010-01-13 | Univ Miami | ANTIBODY IMMUNOCELL LIGAND FUSION PROTEIN FOR CANCER THERAPY |
WO2007143245A2 (en) | 2006-06-01 | 2007-12-13 | Midwest Research Institute | An l-arabinose fermenting yeast |
CA2678618C (en) | 2007-02-21 | 2019-03-12 | Vaccinex, Inc. | Modulation of nkt cell activity with antigen-loaded cd1d molecules |
JP2010531666A (ja) * | 2007-06-26 | 2010-09-30 | ユニバーシティ オブ マイアミ | 抗体−エンドスタチン融合タンパク質及びそのバリアント |
US9611313B2 (en) | 2007-06-26 | 2017-04-04 | University Of Miami | Antibody-endostatin fusion protein and its variants |
US8070021B2 (en) * | 2007-10-31 | 2011-12-06 | Momentive Performance Materials | Hydraulic container evacuator and method |
EP2385980B1 (en) | 2009-01-08 | 2018-04-18 | Albert Einstein College of Medicine, Inc. | Bacterial vaccines with cell wall-associated ceramide-like glycolipids and uses thereof |
JP2013528360A (ja) | 2010-04-09 | 2013-07-11 | アムジェン インコーポレイテッド | Btnl9タンパク質、核酸および抗体ならびにそれらの使用 |
US9593347B2 (en) | 2010-04-16 | 2017-03-14 | University of Pittsburgh—of the Commonwealth System of Higher Education | Identification of mutations in herpes simplex virus envelope glycoproteins that enable or enhance vector retargeting to novel non-HSV receptors |
US9539427B2 (en) | 2010-11-08 | 2017-01-10 | The Johns Hopkins University | Methods for improving heart function |
US10040853B2 (en) * | 2011-09-09 | 2018-08-07 | Fred Hutchinson Cancer Research Center | Methods and compositions involving NKG2D inhibitors and cancer |
US8969519B2 (en) | 2011-09-13 | 2015-03-03 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for brown fat induction and activity using FNDC5 |
US20130156808A1 (en) * | 2011-11-22 | 2013-06-20 | Stipan Jonjic | Vaccine comprising beta-herpesvirus |
CA2878400A1 (en) | 2012-07-19 | 2014-01-23 | Amgen Inc. | Btnl3 proteins, nucleic acids, and antibodies and uses thereof |
UY35148A (es) | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
US9371352B2 (en) | 2013-02-08 | 2016-06-21 | Vaccinex, Inc. | Modified glycolipids and methods of making and using the same |
WO2014144817A2 (en) | 2013-03-15 | 2014-09-18 | Amgen Inc. | Inhibitory polypeptides specific to wnt inhibitors |
AU2014296288B2 (en) | 2013-07-31 | 2020-02-13 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for modulating thermogenesis using PTH-related and EGF-related molecules |
EP3712166A1 (en) | 2013-09-05 | 2020-09-23 | Amgen Inc. | Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles |
NZ720021A (en) | 2013-10-28 | 2022-08-26 | Univ Pittsburgh Commonwealth Sys Higher Education | Oncolytic hsv vector |
EP3094736A4 (en) | 2014-01-14 | 2017-10-25 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for identification, assessment, prevention, and treatment of melanoma using pd-l1 isoforms |
JP6671298B2 (ja) | 2014-05-16 | 2020-03-25 | アムジェン インコーポレイテッド | Th1及びth2細胞集団を検出するためのアッセイ |
US11117969B2 (en) * | 2014-12-05 | 2021-09-14 | Xyphos Biosciences Inc. | Insertable variable fragments of antibodies and modified α1-α2 domains of NKG2D ligands |
CA2963274C (en) | 2014-12-05 | 2024-01-30 | Avidbiotics Corp. | Insertable variable fragments of antibodies and modified a1-a2 domains of nkg2d ligands |
WO2017075329A2 (en) | 2015-10-29 | 2017-05-04 | Dana-Farber Cancer Institute, Inc. | Methods for identification, assessment, prevention, and treatment of metabolic disorders using pm20d1 and n-lipidated amino acids |
DK3408382T3 (da) | 2016-01-27 | 2022-06-20 | Oncorus Inc | Onkolytiske virale vektorer og anvendelser deraf |
MX2018015542A (es) | 2016-06-14 | 2019-10-14 | Univ Pittsburgh Commonwealth Sys Higher Education | Expresion de proteinas de ligando activadoras de nkg2d para la sensibilizacion de celulas cancerosas para el ataque por celulas inmunocitotoxicas. |
MX2019000252A (es) | 2016-06-30 | 2019-10-09 | Oncorus Inc | Administracion viral oncolitica pseudotipada de polipeptidos terapeuticos. |
CN110382685A (zh) | 2016-12-21 | 2019-10-25 | 创新生物科学公司 | 用于提高木糖吸收的表达梅奇酵母木糖转运蛋白的生物和方法 |
CA3047841A1 (en) | 2016-12-21 | 2018-06-28 | Creatus Biosciences Inc. | Xylitol producing metschnikowia species |
SG11201908328XA (en) | 2017-03-14 | 2019-10-30 | Amgen Inc | Control of total afucosylated glycoforms of antibodies produced in cell culture |
SG11202000691XA (en) | 2017-07-26 | 2020-02-27 | Oncorus Inc | Oncolytic viral vectors and uses thereof |
WO2019133847A1 (en) | 2017-12-29 | 2019-07-04 | Oncorus, Inc. | Oncolytic viral delivery of therapeutic polypeptides |
BR112020019559A2 (pt) | 2018-03-26 | 2021-01-12 | Amgen Inc. | Glicoformas afucosiladas totais de anticorpos produzidos em cultura de células |
WO2020051013A2 (en) * | 2018-08-24 | 2020-03-12 | The Trustees Of Columbia University In The City Of New York | Anti-cd33 and nkg2d ligand chimeras for treatment of myeloid malignancies |
BR112022005583A2 (pt) | 2019-09-26 | 2022-09-20 | Amgen Inc | Métodos para a produção de composições de anticorpos |
EP4162257A1 (en) | 2020-06-04 | 2023-04-12 | Amgen Inc. | Assessment of cleaning procedures of a biotherapeutic manufacturing process |
MX2023004364A (es) | 2020-10-15 | 2023-05-03 | Amgen Inc | Glucanos no emparejados relativos en metodos de produccion de anticuerpos. |
WO2022261021A1 (en) | 2021-06-07 | 2022-12-15 | Amgen Inc. | Using fucosidase to control afucosylation level of glycosylated proteins |
AU2022361382A1 (en) | 2021-10-05 | 2024-03-28 | Amgen Inc. | Fc-gamma receptor ii binding and glycan content |
WO2023158732A1 (en) | 2022-02-16 | 2023-08-24 | Dana-Farber Cancer Institute, Inc. | Methods for decreasing pathologic alpha-synuclein using agents that modulate fndc5 or biologically active fragments thereof |
WO2023215725A1 (en) | 2022-05-02 | 2023-11-09 | Fred Hutchinson Cancer Center | Compositions and methods for cellular immunotherapy |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4959314A (en) * | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
USRE38824E1 (en) * | 1986-08-04 | 2005-10-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Antibodies against human herpes virus-6(HHV-6) and method of use |
US5834229A (en) * | 1991-05-24 | 1998-11-10 | Genentech, Inc. | Nucleic acids vectors and host cells encoding and expressing heregulin 2-α |
US5474771A (en) * | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
US5464771A (en) * | 1994-04-29 | 1995-11-07 | The United States Of America As Represented By The Secretary Of Agriculture | Biologically pure culture of Actinomyces viscosus strain used for the bioremediation of chlorinated hydrocarbons |
WO1997038110A2 (en) * | 1996-04-05 | 1997-10-16 | Kieta Holding S.A. | Compositions and methods relating to drug discovery and detection and treatment of gastrointestinal diseases |
US5912415A (en) * | 1996-05-16 | 1999-06-15 | Regents Of The University Of Minnesota | Arabidopsis spindly gene, methods of identification and use |
US20030054987A1 (en) * | 1997-06-16 | 2003-03-20 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
-
1998
- 1998-12-17 WO PCT/US1998/027048 patent/WO1999031241A1/en active IP Right Grant
- 1998-12-17 DE DE69831754T patent/DE69831754T2/de not_active Expired - Lifetime
- 1998-12-17 AT AT98964802T patent/ATE305510T1/de not_active IP Right Cessation
- 1998-12-17 NZ NZ505500A patent/NZ505500A/xx unknown
- 1998-12-17 IL IL13662198A patent/IL136621A0/xx unknown
- 1998-12-17 EP EP98964802A patent/EP1037991B1/en not_active Expired - Lifetime
- 1998-12-17 JP JP2000539141A patent/JP4255211B2/ja not_active Expired - Fee Related
- 1998-12-17 DK DK98964802T patent/DK1037991T3/da active
- 1998-12-17 AU AU20045/99A patent/AU742757C/en not_active Ceased
- 1998-12-17 ES ES98964802T patent/ES2251120T3/es not_active Expired - Lifetime
- 1998-12-17 CA CA002315251A patent/CA2315251A1/en not_active Abandoned
-
2000
- 2000-03-13 US US09/524,100 patent/US6653447B1/en not_active Expired - Fee Related
- 2000-03-22 US US09/532,856 patent/US6458350B1/en not_active Expired - Lifetime
- 2000-06-07 IL IL136621A patent/IL136621A/en not_active IP Right Cessation
-
2002
- 2002-08-05 US US10/212,507 patent/US6774224B2/en not_active Expired - Fee Related
-
2004
- 2004-06-23 US US10/875,869 patent/US7193058B2/en not_active Expired - Fee Related
-
2006
- 2006-12-13 US US11/638,966 patent/US7427669B2/en not_active Expired - Fee Related
-
2008
- 2008-08-04 US US12/221,490 patent/US7807796B2/en not_active Expired - Fee Related
-
2010
- 2010-08-24 US US12/862,629 patent/US8410252B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1037991A1 (en) | 2000-09-27 |
ATE305510T1 (de) | 2005-10-15 |
US7193058B2 (en) | 2007-03-20 |
DE69831754T2 (de) | 2006-06-29 |
NZ505500A (en) | 2002-12-20 |
IL136621A0 (en) | 2001-06-14 |
IL136621A (en) | 2008-07-08 |
US6774224B2 (en) | 2004-08-10 |
US7427669B2 (en) | 2008-09-23 |
AU742757B2 (en) | 2002-01-10 |
US7807796B2 (en) | 2010-10-05 |
US20090324597A1 (en) | 2009-12-31 |
JP2002508183A (ja) | 2002-03-19 |
US8410252B2 (en) | 2013-04-02 |
JP4255211B2 (ja) | 2009-04-15 |
US6653447B1 (en) | 2003-11-25 |
AU2004599A (en) | 1999-07-05 |
DE69831754D1 (de) | 2006-02-09 |
EP1037991B1 (en) | 2005-09-28 |
US20080008715A1 (en) | 2008-01-10 |
AU742757C (en) | 2007-05-17 |
CA2315251A1 (en) | 1999-06-24 |
US20040235058A1 (en) | 2004-11-25 |
US20030147847A1 (en) | 2003-08-07 |
ES2251120T3 (es) | 2006-04-16 |
US6458350B1 (en) | 2002-10-01 |
WO1999031241A1 (en) | 1999-06-24 |
US20110281789A1 (en) | 2011-11-17 |
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