ATE338121T1 - Von muc-1 abgeleitete peptide - Google Patents

Von muc-1 abgeleitete peptide

Info

Publication number
ATE338121T1
ATE338121T1 AT00965943T AT00965943T ATE338121T1 AT E338121 T1 ATE338121 T1 AT E338121T1 AT 00965943 T AT00965943 T AT 00965943T AT 00965943 T AT00965943 T AT 00965943T AT E338121 T1 ATE338121 T1 AT E338121T1
Authority
AT
Austria
Prior art keywords
muc
polypeptides
peptides
peptides derived
ctl
Prior art date
Application number
AT00965943T
Other languages
English (en)
Inventor
Joyce Taylor-Papadimitriou
Lukas Carl Heukamp
Rienk Offringa
Cornelis Johanna Maria Melief
Bruce Acres
Mireille Thomas
Original Assignee
Transgene Sa
Imp Cancer Res Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9921242.5A external-priority patent/GB9921242D0/en
Application filed by Transgene Sa, Imp Cancer Res Tech filed Critical Transgene Sa
Application granted granted Critical
Publication of ATE338121T1 publication Critical patent/ATE338121T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00965943T 1999-09-08 2000-09-07 Von muc-1 abgeleitete peptide ATE338121T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9921242.5A GB9921242D0 (en) 1999-09-08 1999-09-08 Cancer vaccine and diagnosis
EP99402237 1999-09-10
US18721500P 2000-03-03 2000-03-03

Publications (1)

Publication Number Publication Date
ATE338121T1 true ATE338121T1 (de) 2006-09-15

Family

ID=27240232

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00965943T ATE338121T1 (de) 1999-09-08 2000-09-07 Von muc-1 abgeleitete peptide

Country Status (11)

Country Link
US (3) US20050142640A1 (de)
EP (1) EP1210430B1 (de)
JP (1) JP2003510094A (de)
AT (1) ATE338121T1 (de)
AU (1) AU778701B2 (de)
CA (1) CA2383737C (de)
DE (1) DE60030450T2 (de)
DK (1) DK1210430T3 (de)
ES (1) ES2270870T3 (de)
PT (1) PT1210430E (de)
WO (1) WO2001018035A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090004212A1 (en) * 1997-12-30 2009-01-01 Franz-Georg Hanisch Tumour vaccines for MUC1-positive carcinomas
JP2003533181A (ja) * 2000-02-01 2003-11-11 ジ・オースティン・リサーチ・インスティテュート ムチン−１誘導抗原および免疫療法におけるその使用
EP1958642A1 (de) 2000-12-22 2008-08-20 Dana-Farber Cancer Institute Regulierung des Zellwachstums durch MUC1
JP2004533421A (ja) 2001-03-27 2004-11-04 バイオミラ，インコーポレイテッド Ｔ１免疫応答とｔ２免疫応答との間で調節するためのワクチン
DE60238864D1 (de) 2001-11-07 2011-02-17 Mankind Corp Für epitope von antigenen kodierende expressionsvektoren und verfahren zu deren konzeption
JP2006504630A (ja) * 2002-04-22 2006-02-09 ダイアックス コーポレイション ムチンポリペプチドに特異的な抗体
GB0212046D0 (en) * 2002-05-24 2002-07-03 Glaxo Group Ltd Vaccines
GB0212036D0 (en) * 2002-05-24 2002-07-03 Glaxo Group Ltd Vaccines
GB0304634D0 (en) * 2003-02-28 2003-04-02 Glaxo Group Ltd Vaccines
US7696306B2 (en) * 2003-07-11 2010-04-13 Board of Agents of the University of Nebraska Compositions and methods for preventing or treating cancer
GB0321614D0 (en) * 2003-09-15 2003-10-15 Glaxo Group Ltd Vaccines
WO2005042573A1 (en) 2003-10-24 2005-05-12 Dana-Farber Cancer Institute, Inc. Modulation of the interaction of muc1 with muc1 ligands
AU2004299457B2 (en) * 2003-12-12 2011-03-24 Government Of The United States Of America, As Represented By The Secretary Department Of Health And Human Services A human cytotoxic T-lymphocyte epitope and its agonist epitope from the non-variable number of tandem repeat sequence of MUC-1
TW201204410A (en) 2004-04-01 2012-02-01 Oncothyreon Inc Mucinous glycoprotein (MUC-1) vaccine
JP5364371B2 (ja) * 2005-06-28 2013-12-11 オンコセリオン インコーポレイテッド ムチン糖タンパク質（ｍｕｃ−１）ワクチンによって患者を処置する方法
US20090317414A1 (en) * 2006-07-25 2009-12-24 4G Vaccines Pty Ltd Cancer vaccine comprising a mucin 1 (muc1) t cell epitope-derived peptide
AU2007298494B2 (en) 2006-09-21 2013-09-26 Vaxil Biotherapeutics Ltd. Antigen specific multi epitope vaccines
US7871784B2 (en) 2007-02-02 2011-01-18 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of apoptosis by MUC1 and BH3-containing proapoptotic proteins
WO2008097840A2 (en) 2007-02-02 2008-08-14 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of muc1 by hsf1 and stat3
EP2250189A4 (de) * 2008-02-26 2012-07-04 Univ California Gylcopeptide sowie verfahren zu ihrer herstellung und verwendung
US8524669B2 (en) 2008-10-17 2013-09-03 Dana-Farber Cancer Institute, Inc. MUC-1 cytoplasmic domain peptides as inhibitors of cancer
MX2011012625A (es) * 2009-05-27 2012-04-20 Dana Faber Cancer Inst Inc Inhibicion de la inflamacion usando los antagonistas de mucina 1 (muc1).
WO2011100688A1 (en) 2010-02-12 2011-08-18 Dana-Farber Cancer Institute, Inc. Improved antagonists of muc1
EP2374470A1 (de) * 2010-04-08 2011-10-12 Beta Innov Therapeutische Anwendung von Protein Beta-2-M
JP6096111B2 (ja) 2010-05-10 2017-03-15 アセンド・バイオファーマシューティカルズ・リミテッド 免疫刺激組成物及びワクチン組成物
CN105193724A (zh) 2011-02-24 2015-12-30 肿瘤防护公司 含有佐剂的以muc1 为基础的糖脂肽疫苗
RU2642300C2 (ru) 2011-08-17 2018-01-24 Глоубиммьюн, Инк. Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения
WO2013103658A1 (en) * 2012-01-03 2013-07-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Native and agonist ctl epitopes of the muc1 tumor antigen
US9044421B2 (en) 2012-03-28 2015-06-02 Genus Oncology, Llc Treating MUC1-expressing cancers with combination therapies
EP3269726B1 (de) * 2015-03-09 2025-05-07 Nec Corporation Peptid aus muc1, pharmazeutische zusammensetzung zur behandlung oder vorbeugung von krebs damit, immunitätsinduzierer und verfahren zur herstellung von antigen-präsentierenden zellen
CA3057715A1 (en) 2017-04-04 2018-10-11 Avidea Technologies, Inc. Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response
EP3903811A1 (de) * 2020-05-01 2021-11-03 R.G.C.C. Holdings AG Pharmazeutische zusammensetzung und verfahren zur induzierung einer immunantwort

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281061A (en) * 1979-07-27 1981-07-28 Syva Company Double antibody for enhanced sensitivity in immunoassay
CA2003211A1 (en) * 1988-11-17 1990-05-17 Pei-Xiang Xing Monoclonal antibodies
FR2668064B1 (fr) * 1990-10-23 1994-12-16 Transgene Sa Composition pharmaceutique pour le traitement ou la prevention d'une tumeur maligne.
ES2139012T3 (es) * 1992-05-26 2000-02-01 Univ Leiden Peptidos de la proteina p53 humana destinados para ser utilizados en composiciones que inducen una reaccion en los linfocitos t humanos, y linfocitos t citotoxicos especificos de la proteina p53 humana.
IL110464A0 (en) 1994-07-26 1994-10-21 Univ Ramot Novel proteins for the diagnosis, imaging, and therapy of human cancer
US6548643B1 (en) * 1994-11-16 2003-04-15 Austin Research Institute Antigen carbohydrate compounds and their use in immunotherapy
US6024965A (en) 1996-10-18 2000-02-15 Erasums University Rotterdam Induction of REV and TAT specific cytotoxic T-cells for prevention and treatment of human immunodeficiency virus (HIV) infection
JP4480800B2 (ja) * 1997-05-08 2010-06-16 オンコシリオン・インコーポレイテッド 活性化ｔ細胞および抗原パルス標識した抗原提示細胞を生成する方法
AU753540B2 (en) * 1998-03-05 2002-10-24 Agouron Pharmaceuticals, Inc. Non-peptide GnRH agents
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
IL125608A0 (en) * 1998-07-30 1999-03-12 Yeda Res & Dev Tumor associated antigen peptides and use of same as anti-tumor vaccines
US20020052308A1 (en) * 1999-03-12 2002-05-02 Rosen Craig A. Nucleic acids, proteins and antibodies

Also Published As

Publication number Publication date
US20080227082A1 (en) 2008-09-18
AU7651500A (en) 2001-04-10
US20050142640A1 (en) 2005-06-30
CA2383737A1 (en) 2001-03-15
AU778701B2 (en) 2004-12-16
US7892828B2 (en) 2011-02-22
WO2001018035A2 (en) 2001-03-15
EP1210430B1 (de) 2006-08-30
US20100255501A1 (en) 2010-10-07
PT1210430E (pt) 2006-12-29
EP1210430A2 (de) 2002-06-05
CA2383737C (en) 2011-01-18
WO2001018035A3 (en) 2001-11-08
JP2003510094A (ja) 2003-03-18
DE60030450T2 (de) 2007-08-30
ES2270870T3 (es) 2007-04-16
DE60030450D1 (de) 2006-10-12
DK1210430T3 (da) 2006-11-20
WO2001018035A9 (en) 2002-09-06

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