ATE256185T1 - T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen - Google Patents

T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen

Info

Publication number
ATE256185T1
ATE256185T1 AT98945293T AT98945293T ATE256185T1 AT E256185 T1 ATE256185 T1 AT E256185T1 AT 98945293 T AT98945293 T AT 98945293T AT 98945293 T AT98945293 T AT 98945293T AT E256185 T1 ATE256185 T1 AT E256185T1
Authority
AT
Austria
Prior art keywords
cell
peptides
tirc7
membrane protein
cell membrane
Prior art date
Application number
AT98945293T
Other languages
English (en)
Inventor
Nalan Utku
Steven R Gullans
Edgar L Milford
Original Assignee
Brigham & Womens Hospital
Nalan Utku
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19738710A external-priority patent/DE19738710A1/de
Application filed by Brigham & Womens Hospital, Nalan Utku filed Critical Brigham & Womens Hospital
Application granted granted Critical
Publication of ATE256185T1 publication Critical patent/ATE256185T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT98945293T 1997-08-29 1998-08-28 T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen ATE256185T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19738710A DE19738710A1 (de) 1997-08-29 1997-08-29 Verwendung von TIRC7 zur Herstellung von Mitteln zur Inhibition der Immunantwort
DE29802653 1998-02-12
PCT/EP1998/005462 WO1999011782A1 (en) 1997-08-29 1998-08-28 T-cell membrane protein (tirc7), peptides and antibodies derived therefrom and uses thereof

Publications (1)

Publication Number Publication Date
ATE256185T1 true ATE256185T1 (de) 2003-12-15

Family

ID=26039678

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98945293T ATE256185T1 (de) 1997-08-29 1998-08-28 T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen

Country Status (10)

Country Link
EP (2) EP1350848A3 (de)
JP (1) JP4459435B2 (de)
AT (1) ATE256185T1 (de)
AU (1) AU751151C (de)
CA (1) CA2301499C (de)
DE (1) DE69820449T2 (de)
DK (1) DK0996726T3 (de)
ES (1) ES2213295T3 (de)
PT (1) PT996726E (de)
WO (1) WO1999011782A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL134830A0 (en) * 2000-03-01 2001-05-20 Chay 13 Medical Res Group N V Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them
DE60134545D1 (de) * 2000-05-03 2008-08-07 Cellact Pharma Gmbh Verwendungen von tgap7 zur modulation der aktivierung von leukozyten
ATE333889T1 (de) * 2000-10-30 2006-08-15 Genpat77 Pharmacogenetics Ag Verfahren zur gewinnung von inhibitoren der tirc7-liganden-bindung und verwendungszwecke dafür
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7026121B1 (en) 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
CA2486545A1 (en) * 2001-09-17 2003-03-27 Nalan Utku Peptides capable of modulating immune response
US20050118178A1 (en) * 2001-11-27 2005-06-02 Nalan Utku Use of t-cell immune response cdna7 (tirc7) in angiogenic and anti-angiogenic therapy
EP1492817A2 (de) 2001-12-21 2005-01-05 GenPat77 Pharmacogenetics AG Therapeutische, monoklonale, anti-tirc7 antikörper und deren gebrauch in immun- und anderen erkrankungen
WO2003054018A2 (en) * 2001-12-21 2003-07-03 Genpat77 Pharmacogenetics Ag Anti-tirc7 antibodies in therapy of inflammatory diseases
WO2003066091A2 (en) * 2002-02-04 2003-08-14 Nalan Utku Compositions and methods for modulation of effects on phagocyte and lymphoid cell populations employing tirc7
AU2003229728A1 (en) * 2002-04-26 2003-11-10 Genpat77 Pharmacogenetics Ag Bispecific molecules for use in therapy and diagnosis of immune related and other diseases
US20070274998A1 (en) * 2002-04-29 2007-11-29 Genpatzz Pharmacogentetics Ag Novel Bispecific Molecules For Use In Therapy And Diagnosis
EP1891444A2 (de) * 2005-05-17 2008-02-27 GenPat77 Pharmacogenetics AG Tirc7 als marker zur vorzeitigen erkennung einer immunsystem-aktivierung
WO2006122792A1 (en) * 2005-05-17 2006-11-23 Genpat77 Pharmacogenetics Ag Peptides capable of modulating the function of tirc7
DE202011103324U1 (de) 2011-07-12 2012-01-02 Nekonal S.A.R.L. Therapeutische anti-TIRC7 Antikörper für die Verwendung in Immun und anderen Krankheiten
JP2019532303A (ja) 2016-08-09 2019-11-07 ネコナル エス．ア．エール．エル． Ｔｉｒｃ７を基礎とする癌の診断及び治療
JP2019526813A (ja) 2016-08-10 2019-09-19 ネコナル エス．ア．エール．エル． Ｔｉｒｃ７を基礎とする固形癌の診断及び治療
WO2021028579A1 (en) 2019-08-14 2021-02-18 Nekonal S.A.R.L. Method for producing engineered tirc7 specific t-regulatory cells (tregs)

Also Published As

Publication number Publication date
AU751151C (en) 2006-09-14
CA2301499A1 (en) 1999-03-11
EP1350848A3 (de) 2004-02-04
DK0996726T3 (da) 2004-04-13
DE69820449T2 (de) 2005-03-10
ES2213295T3 (es) 2004-08-16
EP0996726A1 (de) 2000-05-03
EP1350848A2 (de) 2003-10-08
JP2001514852A (ja) 2001-09-18
AU751151B2 (en) 2002-08-08
WO1999011782A1 (en) 1999-03-11
CA2301499C (en) 2010-01-26
EP0996726B1 (de) 2003-12-10
PT996726E (pt) 2004-04-30
DE69820449D1 (de) 2004-01-22
JP4459435B2 (ja) 2010-04-28
AU9265498A (en) 1999-03-22

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