DE69820449D1 - T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen - Google Patents
T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungenInfo
- Publication number
- DE69820449D1 DE69820449D1 DE69820449T DE69820449T DE69820449D1 DE 69820449 D1 DE69820449 D1 DE 69820449D1 DE 69820449 T DE69820449 T DE 69820449T DE 69820449 T DE69820449 T DE 69820449T DE 69820449 D1 DE69820449 D1 DE 69820449D1
- Authority
- DE
- Germany
- Prior art keywords
- cell
- tirc7
- membrane protein
- antibodies
- peptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101000854875 Homo sapiens V-type proton ATPase 116 kDa subunit a 3 Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102100020738 V-type proton ATPase 116 kDa subunit a 3 Human genes 0.000 title abstract 3
- 108010052285 Membrane Proteins Proteins 0.000 title 1
- 102000018697 Membrane Proteins Human genes 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 4
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000000172 allergic effect Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001363 autoimmune Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 108091005703 transmembrane proteins Proteins 0.000 abstract 1
- 102000035160 transmembrane proteins Human genes 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69820449T DE69820449T2 (de) | 1997-08-29 | 1998-08-28 | T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19738710A DE19738710A1 (de) | 1997-08-29 | 1997-08-29 | Verwendung von TIRC7 zur Herstellung von Mitteln zur Inhibition der Immunantwort |
DE19738710 | 1997-08-29 | ||
DE29802653 | 1998-02-12 | ||
DE29802653U | 1998-02-12 | ||
PCT/EP1998/005462 WO1999011782A1 (en) | 1997-08-29 | 1998-08-28 | T-cell membrane protein (tirc7), peptides and antibodies derived therefrom and uses thereof |
DE69820449T DE69820449T2 (de) | 1997-08-29 | 1998-08-28 | T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69820449D1 true DE69820449D1 (de) | 2004-01-22 |
DE69820449T2 DE69820449T2 (de) | 2005-03-10 |
Family
ID=26039678
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69820449T Expired - Lifetime DE69820449T2 (de) | 1997-08-29 | 1998-08-28 | T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP1350848A3 (de) |
JP (1) | JP4459435B2 (de) |
AT (1) | ATE256185T1 (de) |
AU (1) | AU751151C (de) |
CA (1) | CA2301499C (de) |
DE (1) | DE69820449T2 (de) |
DK (1) | DK0996726T3 (de) |
ES (1) | ES2213295T3 (de) |
PT (1) | PT996726E (de) |
WO (1) | WO1999011782A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL134830A0 (en) * | 2000-03-01 | 2001-05-20 | Chay 13 Medical Res Group N V | Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them |
ATE399019T1 (de) * | 2000-05-03 | 2008-07-15 | Cellact Pharma Gmbh | Verwendungen von tgap7 zur modulation der aktivierung von leukozyten |
EP1353687B1 (de) * | 2000-10-30 | 2006-07-26 | GenPat77 Pharmacogenetics AG | Verfahren zur gewinnung von inhibitoren der tirc7-liganden-bindung und verwendungszwecke dafür |
US6905827B2 (en) | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
WO2003025000A2 (en) * | 2001-09-17 | 2003-03-27 | Nalan Utku | Peptides capable of modulating immune response |
EP1448227A2 (de) * | 2001-11-27 | 2004-08-25 | GenPat77 Pharmacogenetics AG | Verwendung von "t cell immune response cdna7" (tirc7) zur modulierung der angiogenese und/oder der neovaskularisation |
EP1492818B1 (de) * | 2001-12-21 | 2012-08-08 | CellAct Pharma GmbH | Anti-tirc7 antikörper und tnf-alpha antagonisten zur kombinationstherapie von inflammatorischen erkrankungen |
WO2003054019A2 (en) * | 2001-12-21 | 2003-07-03 | Genpat77 Pharmacogenetics Ag | Therapeutic monoclonal anti-tirc7 antibodies for use in immune related and other diseases |
US20060165689A1 (en) * | 2002-02-04 | 2006-07-27 | Nalan Utku | Compositions and methods for modulation of effects on phagocyte and lymphoid cell populations employing tirc7 |
WO2003091285A1 (en) * | 2002-04-26 | 2003-11-06 | Genpat77 Pharmacogenetics Ag | Bispecific molecules for use in therapy and diagnosis of immune related and other diseases |
CA2484182A1 (en) * | 2002-04-29 | 2003-11-13 | Genpat77 Pharmacogenetics Ag | Novel antibody binding tcr and tirc7 and its use in therapy and diagnosis |
US20110183921A1 (en) * | 2005-05-17 | 2011-07-28 | Jojomed Gmbh | Peptides capable of modulating the function of tirc7 |
WO2006122791A2 (en) * | 2005-05-17 | 2006-11-23 | Genpat77 Pharmacogenetics Ag | Tirc7 as marker for detecting early immune activation |
DE202011103324U1 (de) | 2011-07-12 | 2012-01-02 | Nekonal S.A.R.L. | Therapeutische anti-TIRC7 Antikörper für die Verwendung in Immun und anderen Krankheiten |
EP3496745A1 (de) | 2016-08-09 | 2019-06-19 | Nekonal S.A.R.L. | Auf tirc7 basierende diagnose und therapie von krebs |
AU2017309985A1 (en) | 2016-08-10 | 2019-02-28 | Nekonal S.A.R.L. | TIRC7 based diagnostic and therapy of solid cancer |
US20220288120A1 (en) | 2019-08-14 | 2022-09-15 | Nekonal S.A.R.L. | Method for producing engineered tirc7 specific t-regulatory cells (tregs) |
-
1998
- 1998-08-28 CA CA2301499A patent/CA2301499C/en not_active Expired - Fee Related
- 1998-08-28 PT PT98945293T patent/PT996726E/pt unknown
- 1998-08-28 EP EP03015210A patent/EP1350848A3/de not_active Withdrawn
- 1998-08-28 DK DK98945293T patent/DK0996726T3/da active
- 1998-08-28 DE DE69820449T patent/DE69820449T2/de not_active Expired - Lifetime
- 1998-08-28 ES ES98945293T patent/ES2213295T3/es not_active Expired - Lifetime
- 1998-08-28 WO PCT/EP1998/005462 patent/WO1999011782A1/en active IP Right Grant
- 1998-08-28 AU AU92654/98A patent/AU751151C/en not_active Ceased
- 1998-08-28 AT AT98945293T patent/ATE256185T1/de active
- 1998-08-28 EP EP98945293A patent/EP0996726B1/de not_active Expired - Lifetime
- 1998-08-28 JP JP2000508792A patent/JP4459435B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2213295T3 (es) | 2004-08-16 |
EP1350848A3 (de) | 2004-02-04 |
DE69820449T2 (de) | 2005-03-10 |
CA2301499A1 (en) | 1999-03-11 |
ATE256185T1 (de) | 2003-12-15 |
AU751151B2 (en) | 2002-08-08 |
JP4459435B2 (ja) | 2010-04-28 |
AU9265498A (en) | 1999-03-22 |
DK0996726T3 (da) | 2004-04-13 |
EP0996726B1 (de) | 2003-12-10 |
EP1350848A2 (de) | 2003-10-08 |
CA2301499C (en) | 2010-01-26 |
WO1999011782A1 (en) | 1999-03-11 |
PT996726E (pt) | 2004-04-30 |
JP2001514852A (ja) | 2001-09-18 |
EP0996726A1 (de) | 2000-05-03 |
AU751151C (en) | 2006-09-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: THE BRIGHAM AND WOMEN'S HOSPITAL INC., BOSTON, MAS Owner name: UTKU, NALAN, DR., 10719 BERLIN, DE |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: KOENIG SZYNKA TILMANN VON RENESSE, 40549 DUESSELDO |