NO317049B1 - Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein - Google Patents

Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein Download PDF

Info

Publication number
NO317049B1
NO317049B1 NO19943755A NO943755A NO317049B1 NO 317049 B1 NO317049 B1 NO 317049B1 NO 19943755 A NO19943755 A NO 19943755A NO 943755 A NO943755 A NO 943755A NO 317049 B1 NO317049 B1 NO 317049B1
Authority
NO
Norway
Prior art keywords
mbp
cells
cell
peptide
antigen
Prior art date
Application number
NO19943755A
Other languages
English (en)
Norwegian (no)
Other versions
NO943755D0 (no
NO943755L (no
Inventor
David A Hafler
Howard L Weiner
Ariel Miller
Ahmad Al-Sabbagh
Original Assignee
Autoimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Autoimmune Inc filed Critical Autoimmune Inc
Publication of NO943755D0 publication Critical patent/NO943755D0/no
Publication of NO943755L publication Critical patent/NO943755L/no
Publication of NO317049B1 publication Critical patent/NO317049B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Rehabilitation Therapy (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19943755A 1992-04-09 1994-10-06 Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein NO317049B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86531892A 1992-04-09 1992-04-09
PCT/US1993/003369 WO1993021222A1 (en) 1992-04-09 1993-04-09 Suppression of t-cell proliferation using peptide fragments of myelin basic protein

Publications (3)

Publication Number Publication Date
NO943755D0 NO943755D0 (no) 1994-10-06
NO943755L NO943755L (no) 1994-12-02
NO317049B1 true NO317049B1 (no) 2004-07-26

Family

ID=25345228

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19943755A NO317049B1 (no) 1992-04-09 1994-10-06 Undertrykkelse av T-celleproliferasjon ved anvendelse av fragmenter av myelinbasisk protein

Country Status (15)

Country Link
EP (2) EP0650498B1 (da)
JP (1) JP3434510B2 (da)
KR (1) KR950700934A (da)
AT (2) ATE170874T1 (da)
AU (1) AU680824B2 (da)
BR (1) BR9306272A (da)
CA (1) CA2133749A1 (da)
DE (2) DE69331501T2 (da)
DK (1) DK0863155T3 (da)
ES (1) ES2172044T3 (da)
HU (1) HU219306B (da)
IL (1) IL105347A0 (da)
NO (1) NO317049B1 (da)
PT (1) PT863155E (da)
WO (1) WO1993021222A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869054A (en) * 1987-06-24 1999-02-09 Autoimmune Inc. Treatment of multiple sclerosis by oral administration of autoantigens
US5817629A (en) * 1991-10-22 1998-10-06 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US6252040B1 (en) * 1991-10-22 2001-06-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
PL317197A1 (en) * 1994-05-10 1997-03-17 Immulogic Pharma Corp Compositions for and method of treating sclerosis multiplex
CZ122697A3 (en) * 1994-10-25 1997-09-17 Immulogic Pharma Corp Preparations and methods of treating disseminated sclerosis
US6251396B1 (en) 1994-11-18 2001-06-26 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6329499B1 (en) * 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein
AU721898B2 (en) * 1994-11-18 2000-07-20 Board Of Trustees Of The Leland Stanford Junior University Methods for treatment of multiple sclerosis using peptide analogues at position 91 of human myelin basic protein
US6379670B1 (en) 1994-11-18 2002-04-30 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
WO1996028470A2 (en) * 1995-03-09 1996-09-19 Neurocrine Biosciences, Inc. Peptide analogues of human myelin basic protein useful in treating multiple sclerosis
US5856446A (en) * 1995-07-07 1999-01-05 Autoimmune Inc. Method of treating rheumatoid arthritis with low dose type II collagen
IL116559A (en) * 1995-11-17 2005-11-20 Yissum Res Dev Co Chimeric protein consisting of a bacterial toxin and a myelin basic protein sequence
US6274136B1 (en) * 1996-05-29 2001-08-14 University Of Southern California Construction and use of genes encoding pathogenic epitopes for treatment of autoimmune disease
CA2201841C (en) * 1997-04-04 2010-01-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US20020072493A1 (en) 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
JP2003532618A (ja) * 1998-05-19 2003-11-05 イエダ リサーチ アンド デベロプメント カンパニイ リミテッド 細胞、神経系−特異的抗原およびそれらの用途
ES2292594T3 (es) 2000-05-24 2008-03-16 The Government Of The Usa As Represented By The Secretary Of Department Of Health And Human Services E-selectina para tratar o prevenir accidentes cerebrovasculares.
JP2007509063A (ja) 2003-10-17 2007-04-12 ベイラー カレッジ オブ メディスン Cd8+細胞傷害性t細胞応答を増大させる方法、および多発性硬化症を処置するための方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2172512A1 (en) * 1993-09-22 1995-03-30 Lawrence Steinman Interaction of t-cell receptors and antigen in autoimmune disease
AU721898B2 (en) * 1994-11-18 2000-07-20 Board Of Trustees Of The Leland Stanford Junior University Methods for treatment of multiple sclerosis using peptide analogues at position 91 of human myelin basic protein

Also Published As

Publication number Publication date
EP0863155A1 (en) 1998-09-09
IL105347A0 (en) 1993-08-18
EP0863155B1 (en) 2002-01-23
HU219306B (en) 2001-03-28
KR100295606B1 (da) 2001-10-22
ES2172044T3 (es) 2002-09-16
EP0650498B1 (en) 1998-09-09
EP0650498A4 (en) 1995-06-21
AU680824B2 (en) 1997-08-14
NO943755D0 (no) 1994-10-06
NO943755L (no) 1994-12-02
JP3434510B2 (ja) 2003-08-11
HU9402909D0 (en) 1995-01-30
ATE170874T1 (de) 1998-09-15
DE69320967T2 (de) 1999-05-12
KR950700934A (ko) 1995-02-20
CA2133749A1 (en) 1993-10-28
DK0863155T3 (da) 2002-05-13
AU4282493A (en) 1993-11-18
DE69331501D1 (de) 2002-03-14
HUT69169A (en) 1995-08-28
DE69331501T2 (de) 2002-08-29
BR9306272A (pt) 1998-06-23
DE69320967D1 (de) 1998-10-15
WO1993021222A1 (en) 1993-10-28
EP0650498A1 (en) 1995-05-03
ATE212358T1 (de) 2002-02-15
PT863155E (pt) 2002-07-31
JPH08500083A (ja) 1996-01-09

Similar Documents

Publication Publication Date Title
US11718650B2 (en) Immunogenic peptides and their use in immune disorders
US5858980A (en) Peptide fragments of myelin basic protein
US8343500B2 (en) Peptide composition
EP0863155B1 (en) Suppression of T-cell proliferation using peptide fragments of myelin basic protein
AU651350B2 (en) Multiple sclerosis T-cell receptor
SI9520118A (sl) Sestavki in zdravljenje multiple skleroze
AU674494B2 (en) T cell receptor peptides as therapeutics for immune-related disease
CN105121463B (zh)
US20030220229A1 (en) Proinsulin peptide compounds for detecting and treating type I diabetes
Richert Human T-cell recognition of myelin basic protein peptides
US6509165B1 (en) Detection methods for type I diabetes
EP0825870A1 (en) Modulation of cytokine patterns of human autoreactive t-cell clones
AU738564B2 (en) Proinsulin peptide compounds for detecting and treating type I diabetes
AU9724801A (en) Proinsulin peptide compounds for detecting and treating type I diabetes

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees