NO312708B1 - Radioaktive liposomer til terapi - Google Patents
Radioaktive liposomer til terapi Download PDFInfo
- Publication number
- NO312708B1 NO312708B1 NO20000855A NO20000855A NO312708B1 NO 312708 B1 NO312708 B1 NO 312708B1 NO 20000855 A NO20000855 A NO 20000855A NO 20000855 A NO20000855 A NO 20000855A NO 312708 B1 NO312708 B1 NO 312708B1
- Authority
- NO
- Norway
- Prior art keywords
- liposomes
- stated
- composition
- radionuclide
- solution
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title claims description 124
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1072—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from the reproductive system, e.g. ovaria, uterus, testes or prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
- A61K51/1234—Liposomes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Optics & Photonics (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Priority Applications (22)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20000855A NO312708B1 (no) | 2000-02-21 | 2000-02-21 | Radioaktive liposomer til terapi |
| NZ520848A NZ520848A (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| CZ20023164A CZ299032B6 (cs) | 2000-02-21 | 2001-02-21 | Konjugátorový systém |
| JP2001559512A JP4933712B2 (ja) | 2000-02-21 | 2001-02-21 | 放射線治療用リポソーム |
| UA2002086850A UA73160C2 (ru) | 2000-02-21 | 2001-02-21 | Конъюгационная система, представляющая собой радиоактивные терапевтические липосомы, способ получения и применения |
| BR0108572-7A BR0108572A (pt) | 2000-02-21 | 2001-02-21 | Sistema conjugador, método para preparar um sistema conjugador radiorrotulado, uso do sistema conjugador, método para utilizar o sistema conjugador, e, kit para a preparação do sistema conjugador |
| DE60112251T DE60112251T2 (de) | 2000-02-21 | 2001-02-21 | Radioaktive therapeutische liposomen |
| AT01910251T ATE300316T1 (de) | 2000-02-21 | 2001-02-21 | Radioaktive therapeutische liposomen |
| KR1020027010848A KR100822566B1 (ko) | 2000-02-21 | 2001-02-21 | 방사성 치료 리포좀 |
| PCT/NO2001/000065 WO2001060417A2 (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| EA200200793A EA005624B1 (ru) | 2000-02-21 | 2001-02-21 | Радиоактивные терапевтические липосомы |
| CNB018053726A CN100350981C (zh) | 2000-02-21 | 2001-02-21 | 有放射活性的治疗性脂质体 |
| US09/790,260 US6592843B2 (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| CA002400994A CA2400994C (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| PL358541A PL201398B1 (pl) | 2000-02-21 | 2001-02-21 | System koniugatora radionuklid-liposom, sposób jego wytwarzania, zastosowanie systemu koniugatora do wytwarzania roztworu farmaceutycznego, zastosowanie terapeutyczne systemu koniugatora oraz zestaw do wytwarzania systemu koniugatora |
| DK01910251T DK1257299T3 (da) | 2000-02-21 | 2001-02-21 | Radioaktive, terapeutiske liposomer |
| MXPA02008110A MXPA02008110A (es) | 2000-02-21 | 2001-02-21 | Liposomas terapeuticos radioactivos. |
| AU2001237827A AU2001237827B2 (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| ES01910251T ES2247069T3 (es) | 2000-02-21 | 2001-02-21 | Liposomas terapeuticos radioactivos. |
| EP01910251A EP1257299B9 (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| AU3782701A AU3782701A (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| ZA200206500A ZA200206500B (en) | 2000-02-21 | 2002-08-14 | Radioactive therapeutic liposomes. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20000855A NO312708B1 (no) | 2000-02-21 | 2000-02-21 | Radioaktive liposomer til terapi |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20000855D0 NO20000855D0 (no) | 2000-02-21 |
| NO20000855L NO20000855L (no) | 2001-08-22 |
| NO312708B1 true NO312708B1 (no) | 2002-06-24 |
Family
ID=19910768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20000855A NO312708B1 (no) | 2000-02-21 | 2000-02-21 | Radioaktive liposomer til terapi |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6592843B2 (ru) |
| EP (1) | EP1257299B9 (ru) |
| JP (1) | JP4933712B2 (ru) |
| KR (1) | KR100822566B1 (ru) |
| CN (1) | CN100350981C (ru) |
| AT (1) | ATE300316T1 (ru) |
| AU (2) | AU2001237827B2 (ru) |
| BR (1) | BR0108572A (ru) |
| CA (1) | CA2400994C (ru) |
| CZ (1) | CZ299032B6 (ru) |
| DE (1) | DE60112251T2 (ru) |
| DK (1) | DK1257299T3 (ru) |
| EA (1) | EA005624B1 (ru) |
| ES (1) | ES2247069T3 (ru) |
| MX (1) | MXPA02008110A (ru) |
| NO (1) | NO312708B1 (ru) |
| NZ (1) | NZ520848A (ru) |
| PL (1) | PL201398B1 (ru) |
| UA (1) | UA73160C2 (ru) |
| WO (1) | WO2001060417A2 (ru) |
| ZA (1) | ZA200206500B (ru) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO310544B1 (no) * | 1999-01-04 | 2001-07-23 | Algeta As | Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben |
| NO314537B1 (no) * | 1999-12-06 | 2003-04-07 | Anticancer Therapeutic Inv Sa | Reseptorbindende konjugater |
| US8029795B2 (en) * | 1999-12-30 | 2011-10-04 | Gwathmey, Inc. | Targeted iron chelator delivery system |
| US20040166060A1 (en) * | 2000-06-16 | 2004-08-26 | Sloan Kettering Institute For Cancer Research | Liposomal encapsulation of alpha particle emittors and uses thereof |
| EP1289570B1 (en) * | 2000-06-16 | 2008-09-10 | Sloan-Kettering Institute For Cancer Research | Liposomal encapsulation of alpha-emitters and uses thereof |
| NO313180B1 (no) * | 2000-07-04 | 2002-08-26 | Anticancer Therapeutic Inv Sa | Bensökende alfapartikkel emitterende radiofarmasöytika |
| US6869591B2 (en) * | 2002-03-26 | 2005-03-22 | Barnes-Jewish Hospital | Paramagnetic particles that provide improved relaxivity |
| GB0213261D0 (en) * | 2002-06-10 | 2002-07-17 | Anticancer Therapeutic Inv Sa | Method |
| EA008195B1 (ru) * | 2003-04-15 | 2007-04-27 | Алгета Ас | Применение тория-227 в лучевой терапии заболеваний мягких тканей |
| GB0308731D0 (en) * | 2003-04-15 | 2003-05-21 | Anticancer Therapeutic Inv Sa | Method of radiotherapy |
| JP2007505043A (ja) * | 2003-09-09 | 2007-03-08 | ギリアード サイエンシーズ， インコーポレイテッド | 処置用リポソーム |
| WO2005079867A2 (en) * | 2004-02-20 | 2005-09-01 | Algeta As | Alpha-emitting hydroxyapatite particles |
| US20070053845A1 (en) * | 2004-03-02 | 2007-03-08 | Shiladitya Sengupta | Nanocell drug delivery system |
| CN101031287A (zh) * | 2004-03-02 | 2007-09-05 | 麻省理工学院 | 纳米细胞药物递送系统 |
| GB0423565D0 (en) * | 2004-10-22 | 2004-11-24 | Algeta As | Formulation |
| US20070065359A1 (en) * | 2005-03-14 | 2007-03-22 | Shiladitya Sengupta | Nanocells for diagnosis and treatment of diseases and disorders |
| US8709380B1 (en) * | 2006-02-07 | 2014-04-29 | Sirius Medicine, Llc | Targeting agents for enhancing radiation therapy |
| US20070224115A1 (en) * | 2006-03-22 | 2007-09-27 | The Regents Of The University Of California | Polymeric chelators for radionuclide delivery systems |
| CN101485629B (zh) * | 2008-01-16 | 2013-01-23 | 沈阳药科大学 | 一种给药系统及其制备方法 |
| US20100178244A1 (en) * | 2009-01-13 | 2010-07-15 | Arnsdorf Morton F | Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites |
| US20100178245A1 (en) * | 2009-01-13 | 2010-07-15 | Arnsdorf Morton F | Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites |
| WO2010135714A2 (en) | 2009-05-22 | 2010-11-25 | The Methodist Hospital Research Institute | Methods for modulating adipocyte expression using microrna compositions |
| CA2768444A1 (en) | 2009-07-17 | 2011-01-20 | Rigshospitalet | Loading technique for preparing radionuclide and ionophore containing liposomes in which the ionophore is 2-hydroxyquionoline (carbostyril) or structurally related 2-hydroxyquinolines |
| JP2011111438A (ja) * | 2009-11-30 | 2011-06-09 | Akita Univ | 有機金属錯体を有効成分として含有する抗がん剤 |
| GB201002508D0 (en) | 2010-02-12 | 2010-03-31 | Algeta As | Product |
| WO2012079582A1 (en) | 2010-12-14 | 2012-06-21 | Technical University Of Denmark | Entrapment of radionuclides in nanoparticle compositions |
| GB201105298D0 (en) * | 2011-03-29 | 2011-05-11 | Algeta Asa | Pharmaceutical preparation |
| DE102011079031A1 (de) * | 2011-07-12 | 2013-01-17 | Algeta Asa | Flüssigkeitsbehälter |
| GB201208309D0 (en) | 2012-05-11 | 2012-06-27 | Algeta As | Complexes |
| WO2014164712A1 (en) | 2013-03-11 | 2014-10-09 | Wayne State University | Formation and uses of europium |
| NO3061464T3 (ru) * | 2015-02-26 | 2018-03-24 | ||
| DK3261681T3 (da) * | 2015-02-26 | 2020-04-27 | Sciencons AS | Radiofarmaceutiske opløsninger med fordelagtige egenskaber |
| US9433690B1 (en) * | 2015-02-26 | 2016-09-06 | Sciencons AS | Radiopharmaceutical solutions with advantageous properties |
| EP3111959B1 (en) * | 2015-07-03 | 2017-09-13 | Oncoinvent AS | Radiotherapeutic particles and suspensions |
| MX2018011629A (es) | 2016-03-24 | 2019-03-14 | Bayer Pharma AG | Complejos radiofarmaceuticos. |
| BR112018075554A2 (pt) | 2016-06-10 | 2019-10-01 | Bayer As | complexos radiofarmacêuticos |
| MX2018016121A (es) * | 2016-06-24 | 2019-05-30 | Sciencons AS | Preparacion de anticuerpos monoclonales marcados con 212pb. |
| RU2763750C2 (ru) | 2017-05-11 | 2022-01-10 | Альфа Тау Медикал Лтд. | Полимерные покрытия для брахитерапевтических устройств |
| KR20200139722A (ko) | 2018-04-02 | 2020-12-14 | 알파 타우 메디컬 리미티드 | 방사성 핵종의 제어된 방출 |
| CA3148382A1 (en) | 2019-07-25 | 2021-01-28 | Bayer As | Targeted radiopharmaceuticals for the diagnosis and treatment of prostate cancer |
| JP2024503995A (ja) | 2020-12-16 | 2024-01-30 | アルファ タウ メディカル リミテッド | ベータ線治療を強化した拡散アルファ放射体放射線治療 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4310506A (en) * | 1979-02-22 | 1982-01-12 | California Institute Of Technology | Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species |
| DK482685D0 (da) * | 1984-10-22 | 1985-10-21 | Hope Nat Medical Center | Fremgangsmaade til tilfoersel af micellulaere partikler, der indkapslerbilleddannende og kemoterapeutiske midler, til tumorer i et legeme |
| CA1314209C (en) * | 1987-11-04 | 1993-03-09 | Gary Fujii | Composition and method for use for liposome encapsulated compounds for neutron capture tumor therapy |
| US5527528A (en) * | 1989-10-20 | 1996-06-18 | Sequus Pharmaceuticals, Inc. | Solid-tumor treatment method |
| EP1138334A3 (en) * | 1992-06-09 | 2002-04-03 | Neorx Corporation | Pretargeting methods and compounds |
| GB9420390D0 (en) * | 1994-10-10 | 1994-11-23 | Nycomed Salutar Inc | Liposomal agents |
| CA2333125C (en) * | 1998-05-26 | 2009-12-15 | Sloan-Kettering Institute For Cancer Research | Alpha emitting constructs and uses thereof |
-
2000
- 2000-02-21 NO NO20000855A patent/NO312708B1/no not_active IP Right Cessation
-
2001
- 2001-02-21 MX MXPA02008110A patent/MXPA02008110A/es active IP Right Grant
- 2001-02-21 AU AU2001237827A patent/AU2001237827B2/en not_active Ceased
- 2001-02-21 KR KR1020027010848A patent/KR100822566B1/ko not_active IP Right Cessation
- 2001-02-21 EA EA200200793A patent/EA005624B1/ru not_active IP Right Cessation
- 2001-02-21 CZ CZ20023164A patent/CZ299032B6/cs not_active IP Right Cessation
- 2001-02-21 ES ES01910251T patent/ES2247069T3/es not_active Expired - Lifetime
- 2001-02-21 NZ NZ520848A patent/NZ520848A/en not_active IP Right Cessation
- 2001-02-21 WO PCT/NO2001/000065 patent/WO2001060417A2/en active IP Right Grant
- 2001-02-21 BR BR0108572-7A patent/BR0108572A/pt not_active IP Right Cessation
- 2001-02-21 US US09/790,260 patent/US6592843B2/en not_active Expired - Lifetime
- 2001-02-21 DK DK01910251T patent/DK1257299T3/da active
- 2001-02-21 JP JP2001559512A patent/JP4933712B2/ja not_active Expired - Fee Related
- 2001-02-21 CN CNB018053726A patent/CN100350981C/zh not_active Expired - Fee Related
- 2001-02-21 AT AT01910251T patent/ATE300316T1/de active
- 2001-02-21 PL PL358541A patent/PL201398B1/pl unknown
- 2001-02-21 CA CA002400994A patent/CA2400994C/en not_active Expired - Fee Related
- 2001-02-21 DE DE60112251T patent/DE60112251T2/de not_active Expired - Lifetime
- 2001-02-21 UA UA2002086850A patent/UA73160C2/ru unknown
- 2001-02-21 AU AU3782701A patent/AU3782701A/xx active Pending
- 2001-02-21 EP EP01910251A patent/EP1257299B9/en not_active Expired - Lifetime
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2002
- 2002-08-14 ZA ZA200206500A patent/ZA200206500B/en unknown
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