MXPA02008110A - Liposomas terapeuticos radioactivos. - Google Patents

Liposomas terapeuticos radioactivos.

Info

Publication number
MXPA02008110A
MXPA02008110A MXPA02008110A MXPA02008110A MXPA02008110A MX PA02008110 A MXPA02008110 A MX PA02008110A MX PA02008110 A MXPA02008110 A MX PA02008110A MX PA02008110 A MXPA02008110 A MX PA02008110A MX PA02008110 A MXPA02008110 A MX PA02008110A
Authority
MX
Mexico
Prior art keywords
liposomes
radioactive therapeutic
therapeutic liposomes
radioactive
ionophores
Prior art date
Application number
MXPA02008110A
Other languages
English (en)
Inventor
Roy H Larsen
Original Assignee
Anticancer Therapeutic Inv Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anticancer Therapeutic Inv Sa filed Critical Anticancer Therapeutic Inv Sa
Publication of MXPA02008110A publication Critical patent/MXPA02008110A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1072—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from the reproductive system, e.g. ovaria, uterus, testes or prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1234—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MXPA02008110A 2000-02-21 2001-02-21 Liposomas terapeuticos radioactivos. MXPA02008110A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20000855A NO312708B1 (no) 2000-02-21 2000-02-21 Radioaktive liposomer til terapi
PCT/NO2001/000065 WO2001060417A2 (en) 2000-02-21 2001-02-21 Radioactive therapeutic liposomes

Publications (1)

Publication Number Publication Date
MXPA02008110A true MXPA02008110A (es) 2003-12-11

Family

ID=19910768

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02008110A MXPA02008110A (es) 2000-02-21 2001-02-21 Liposomas terapeuticos radioactivos.

Country Status (21)

Country Link
US (1) US6592843B2 (es)
EP (1) EP1257299B9 (es)
JP (1) JP4933712B2 (es)
KR (1) KR100822566B1 (es)
CN (1) CN100350981C (es)
AT (1) ATE300316T1 (es)
AU (2) AU3782701A (es)
BR (1) BR0108572A (es)
CA (1) CA2400994C (es)
CZ (1) CZ299032B6 (es)
DE (1) DE60112251T2 (es)
DK (1) DK1257299T3 (es)
EA (1) EA005624B1 (es)
ES (1) ES2247069T3 (es)
MX (1) MXPA02008110A (es)
NO (1) NO312708B1 (es)
NZ (1) NZ520848A (es)
PL (1) PL201398B1 (es)
UA (1) UA73160C2 (es)
WO (1) WO2001060417A2 (es)
ZA (1) ZA200206500B (es)

Families Citing this family (41)

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NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
US8029795B2 (en) * 1999-12-30 2011-10-04 Gwathmey, Inc. Targeted iron chelator delivery system
ES2312448T3 (es) * 2000-06-16 2009-03-01 Sloan-Kettering Institute For Cancer Research Encapsulacion liposomica de emisores alfa y sus usos.
US20040166060A1 (en) * 2000-06-16 2004-08-26 Sloan Kettering Institute For Cancer Research Liposomal encapsulation of alpha particle emittors and uses thereof
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
US6869591B2 (en) * 2002-03-26 2005-03-22 Barnes-Jewish Hospital Paramagnetic particles that provide improved relaxivity
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
KR20060015507A (ko) * 2003-04-15 2006-02-17 알게타 에이에스 연조직 질환의 방사선 치료에 사용하기 위한 토륨-227
CA2536393A1 (en) * 2003-09-09 2005-06-16 Gilead Sciences, Inc. Use of liposomes which are small unilamellar vesicles for the removal of an entity from a biological sample
BRPI0507824A (pt) * 2004-02-20 2007-07-10 Algeta As hidroxiapatita, processo para a preparação de um particulado de hidroxiapatita marcada com radionuclìdeo, composição farmacêutica, uso de hidroxiapatita e de um radionuclìdeo emissor de alfa ou um radionuclìdeo emissor de beta, dispositivo, e, método de tratamento radioquìmico de um ser humano ou de um indivìduo animal não humano necessitando do mesmo
US20070053845A1 (en) * 2004-03-02 2007-03-08 Shiladitya Sengupta Nanocell drug delivery system
EP1722762A2 (en) * 2004-03-02 2006-11-22 Massachusetts Institute of Technology Nanocell drug delivery system
GB0423565D0 (en) * 2004-10-22 2004-11-24 Algeta As Formulation
US20090110633A1 (en) * 2005-03-14 2009-04-30 Shiladitya Sengupta Nanocells for Diagnosis and Treatment of Diseases and Disorders
US8709380B1 (en) * 2006-02-07 2014-04-29 Sirius Medicine, Llc Targeting agents for enhancing radiation therapy
US20070224115A1 (en) * 2006-03-22 2007-09-27 The Regents Of The University Of California Polymeric chelators for radionuclide delivery systems
CN101485629B (zh) * 2008-01-16 2013-01-23 沈阳药科大学 一种给药系统及其制备方法
US20100178245A1 (en) * 2009-01-13 2010-07-15 Arnsdorf Morton F Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites
US20100178244A1 (en) * 2009-01-13 2010-07-15 Arnsdorf Morton F Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites
WO2010135714A2 (en) 2009-05-22 2010-11-25 The Methodist Hospital Research Institute Methods for modulating adipocyte expression using microrna compositions
CA2768444A1 (en) 2009-07-17 2011-01-20 Rigshospitalet Loading technique for preparing radionuclide and ionophore containing liposomes in which the ionophore is 2-hydroxyquionoline (carbostyril) or structurally related 2-hydroxyquinolines
JP2011111438A (ja) * 2009-11-30 2011-06-09 Akita Univ 有機金属錯体を有効成分として含有する抗がん剤
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
DK2651447T3 (en) * 2010-12-14 2018-12-17 Univ Denmark Tech Dtu Capture of radionuclides in nanoparticle compositions
GB201105298D0 (en) * 2011-03-29 2011-05-11 Algeta Asa Pharmaceutical preparation
DE102011079031A1 (de) * 2011-07-12 2013-01-17 Algeta Asa Flüssigkeitsbehälter
GB201208309D0 (en) 2012-05-11 2012-06-27 Algeta As Complexes
US20160022842A1 (en) 2013-03-11 2016-01-28 Wayne State University Formation and uses of europium
NO3061464T3 (es) * 2015-02-26 2018-03-24
AU2016223475B2 (en) * 2015-02-26 2021-04-08 Sciencons AS Radiopharmaceutical solutions with advantageous properties
US9433690B1 (en) * 2015-02-26 2016-09-06 Sciencons AS Radiopharmaceutical solutions with advantageous properties
EP3111959B1 (en) * 2015-07-03 2017-09-13 Oncoinvent AS Radiotherapeutic particles and suspensions
WO2017162555A1 (en) 2016-03-24 2017-09-28 Bayer Pharma Aktiengesellschaft Radio-pharmaceutical complexes
CA3026900A1 (en) 2016-06-10 2017-12-14 Bayer Pharma Aktiengesellschaft Radio-pharmaceutical complexes
AU2017281649B2 (en) * 2016-06-24 2023-07-27 Sciencons AS Preparation of 212Pb labeled monoclonal antibodies
CN110603076A (zh) 2017-05-11 2019-12-20 阿尔法陶医疗有限公司 用于近距离放射治疗装置的聚合物涂层
US11969485B2 (en) 2018-04-02 2024-04-30 Alpha Tau Medical Ltd. Controlled release of radionuclides
US20230072421A1 (en) 2019-07-25 2023-03-09 Bayer As Targeted radiopharmaceuticals for the diagnosis and treatment of prostate cancer
CA3202211A1 (en) 2020-12-16 2022-06-23 Alpha Tau Medical Ltd. Diffusing alpha-emitters radiation therapy with enhanced beta treatment

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310506A (en) * 1979-02-22 1982-01-12 California Institute Of Technology Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species
DK482685D0 (da) * 1984-10-22 1985-10-21 Hope Nat Medical Center Fremgangsmaade til tilfoersel af micellulaere partikler, der indkapslerbilleddannende og kemoterapeutiske midler, til tumorer i et legeme
EP0386146B1 (en) * 1987-11-04 1993-04-28 Vestar, Inc. Composition and method of use for liposome encapsulated compounds for neutron capture tumor therapy
US5527528A (en) * 1989-10-20 1996-06-18 Sequus Pharmaceuticals, Inc. Solid-tumor treatment method
EP1138334A3 (en) * 1992-06-09 2002-04-03 Neorx Corporation Pretargeting methods and compounds
GB9420390D0 (en) * 1994-10-10 1994-11-23 Nycomed Salutar Inc Liposomal agents
JP5064608B2 (ja) * 1998-05-26 2012-10-31 スローン−ケッタリング インスティトゥート フォー カンサー リサーチ アルファ粒子放出構成物およびその使用方法

Also Published As

Publication number Publication date
DE60112251D1 (de) 2005-09-01
PL358541A1 (en) 2004-08-09
EP1257299B9 (en) 2005-11-30
CA2400994A1 (en) 2001-08-23
KR100822566B1 (ko) 2008-04-16
CN100350981C (zh) 2007-11-28
PL201398B1 (pl) 2009-04-30
DE60112251T2 (de) 2006-03-30
US6592843B2 (en) 2003-07-15
BR0108572A (pt) 2002-11-19
DK1257299T3 (da) 2005-11-21
WO2001060417A3 (en) 2002-02-07
UA73160C2 (uk) 2005-06-15
NZ520848A (en) 2005-02-25
US20010048914A1 (en) 2001-12-06
CA2400994C (en) 2009-07-07
CZ299032B6 (cs) 2008-04-09
CN1404402A (zh) 2003-03-19
JP2003522808A (ja) 2003-07-29
NO20000855D0 (no) 2000-02-21
JP4933712B2 (ja) 2012-05-16
ATE300316T1 (de) 2005-08-15
EA005624B1 (ru) 2005-04-28
WO2001060417A2 (en) 2001-08-23
EP1257299A2 (en) 2002-11-20
AU3782701A (en) 2001-08-27
AU2001237827B8 (en) 2001-08-27
NO312708B1 (no) 2002-06-24
EA200200793A1 (ru) 2003-02-27
AU2001237827B2 (en) 2007-11-22
ZA200206500B (en) 2003-08-14
ES2247069T3 (es) 2006-03-01
NO20000855L (no) 2001-08-22
KR20020092963A (ko) 2002-12-12
EP1257299B1 (en) 2005-07-27
CZ20023164A3 (cs) 2003-04-16

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