MXPA02008110A - Liposomas terapeuticos radioactivos. - Google Patents

Liposomas terapeuticos radioactivos.

Info

Publication number
MXPA02008110A
MXPA02008110A MXPA02008110A MXPA02008110A MXPA02008110A MX PA02008110 A MXPA02008110 A MX PA02008110A MX PA02008110 A MXPA02008110 A MX PA02008110A MX PA02008110 A MXPA02008110 A MX PA02008110A MX PA02008110 A MXPA02008110 A MX PA02008110A
Authority
MX
Mexico
Prior art keywords
liposomes
radioactive therapeutic
therapeutic liposomes
radioactive
ionophores
Prior art date
Application number
MXPA02008110A
Other languages
English (en)
Inventor
Roy H Larsen
Original Assignee
Anticancer Therapeutic Inv Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anticancer Therapeutic Inv Sa filed Critical Anticancer Therapeutic Inv Sa
Publication of MXPA02008110A publication Critical patent/MXPA02008110A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1072—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from the reproductive system, e.g. ovaria, uterus, testes or prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1234—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MXPA02008110A 2000-02-21 2001-02-21 Liposomas terapeuticos radioactivos. MXPA02008110A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20000855A NO312708B1 (no) 2000-02-21 2000-02-21 Radioaktive liposomer til terapi
PCT/NO2001/000065 WO2001060417A2 (en) 2000-02-21 2001-02-21 Radioactive therapeutic liposomes

Publications (1)

Publication Number Publication Date
MXPA02008110A true MXPA02008110A (es) 2003-12-11

Family

ID=19910768

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02008110A MXPA02008110A (es) 2000-02-21 2001-02-21 Liposomas terapeuticos radioactivos.

Country Status (21)

Country Link
US (1) US6592843B2 (es)
EP (1) EP1257299B9 (es)
JP (1) JP4933712B2 (es)
KR (1) KR100822566B1 (es)
CN (1) CN100350981C (es)
AT (1) ATE300316T1 (es)
AU (2) AU2001237827B2 (es)
BR (1) BR0108572A (es)
CA (1) CA2400994C (es)
CZ (1) CZ299032B6 (es)
DE (1) DE60112251T2 (es)
DK (1) DK1257299T3 (es)
EA (1) EA005624B1 (es)
ES (1) ES2247069T3 (es)
MX (1) MXPA02008110A (es)
NO (1) NO312708B1 (es)
NZ (1) NZ520848A (es)
PL (1) PL201398B1 (es)
UA (1) UA73160C2 (es)
WO (1) WO2001060417A2 (es)
ZA (1) ZA200206500B (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO310544B1 (no) * 1999-01-04 2001-07-23 Algeta As Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben
NO314537B1 (no) * 1999-12-06 2003-04-07 Anticancer Therapeutic Inv Sa Reseptorbindende konjugater
US8029795B2 (en) * 1999-12-30 2011-10-04 Gwathmey, Inc. Targeted iron chelator delivery system
ES2312448T3 (es) * 2000-06-16 2009-03-01 Sloan-Kettering Institute For Cancer Research Encapsulacion liposomica de emisores alfa y sus usos.
US20040166060A1 (en) * 2000-06-16 2004-08-26 Sloan Kettering Institute For Cancer Research Liposomal encapsulation of alpha particle emittors and uses thereof
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
US6869591B2 (en) * 2002-03-26 2005-03-22 Barnes-Jewish Hospital Paramagnetic particles that provide improved relaxivity
GB0213261D0 (en) * 2002-06-10 2002-07-17 Anticancer Therapeutic Inv Sa Method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
PL1617876T3 (pl) * 2003-04-15 2015-03-31 Algeta Asa Tor-227 do zastosowania w radioterapii choroby tkanek miękkich
JP2007505043A (ja) * 2003-09-09 2007-03-08 ギリアード サイエンシーズ， インコーポレイテッド 処置用リポソーム
EP1735013B1 (en) * 2004-02-20 2012-02-08 Algeta ASA Alpha- and beta-emitting hydroxyapatite particles
EP1722762A2 (en) * 2004-03-02 2006-11-22 Massachusetts Institute of Technology Nanocell drug delivery system
US20070053845A1 (en) * 2004-03-02 2007-03-08 Shiladitya Sengupta Nanocell drug delivery system
GB0423565D0 (en) * 2004-10-22 2004-11-24 Algeta As Formulation
EP1861072A2 (en) * 2005-03-14 2007-12-05 Massachusetts Institute Of Technology Nanocells for diagnosis and treatment of diseases and disorders
US8709380B1 (en) * 2006-02-07 2014-04-29 Sirius Medicine, Llc Targeting agents for enhancing radiation therapy
US20070224115A1 (en) * 2006-03-22 2007-09-27 The Regents Of The University Of California Polymeric chelators for radionuclide delivery systems
CN101485629B (zh) * 2008-01-16 2013-01-23 沈阳药科大学 一种给药系统及其制备方法
US20100178245A1 (en) * 2009-01-13 2010-07-15 Arnsdorf Morton F Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites
US20100178244A1 (en) * 2009-01-13 2010-07-15 Arnsdorf Morton F Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites
WO2010135714A2 (en) 2009-05-22 2010-11-25 The Methodist Hospital Research Institute Methods for modulating adipocyte expression using microrna compositions
AU2010272957B2 (en) * 2009-07-17 2016-03-03 Rigshospitalet Loading technique for preparing radionuclide and ionophore containing liposomes in which the ionophore is 2-hydroxyquionoline (carbostyril) or structurally related 2-hydroxyquinolines
JP2011111438A (ja) * 2009-11-30 2011-06-09 Akita Univ 有機金属錯体を有効成分として含有する抗がん剤
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
EP2651447B1 (en) 2010-12-14 2018-08-29 Technical University of Denmark Entrapment of radionuclides in nanoparticle compositions
GB201105298D0 (en) * 2011-03-29 2011-05-11 Algeta Asa Pharmaceutical preparation
DE102011079031A1 (de) * 2011-07-12 2013-01-17 Algeta Asa Flüssigkeitsbehälter
GB201208309D0 (en) 2012-05-11 2012-06-27 Algeta As Complexes
WO2014164712A1 (en) * 2013-03-11 2014-10-09 Wayne State University Formation and uses of europium
ES2657388T3 (es) * 2015-02-26 2018-03-05 Sciencons AS Disoluciones radiofarmacéuticas con propiedades ventajosas
US9433690B1 (en) * 2015-02-26 2016-09-06 Sciencons AS Radiopharmaceutical solutions with advantageous properties
RU2741794C2 (ru) * 2015-02-26 2021-01-28 Сайенконс Ас Радиофармацевтические растворы с предпочтительными свойствами
EP3111959B1 (en) * 2015-07-03 2017-09-13 Oncoinvent AS Radiotherapeutic particles and suspensions
BR112018069485A2 (pt) 2016-03-24 2019-07-30 Bayer As complexos radiofarmacêuticos
MA45225A (fr) 2016-06-10 2019-04-17 Bayer As Complexes radiopharmaceutiques
WO2017220767A1 (en) * 2016-06-24 2017-12-28 Sciencons AS Preparation of 212pb labeled monoclonal antibodies
WO2018207105A1 (en) 2017-05-11 2018-11-15 Alpha Tau Medical Ltd. Polymer coatings for brachytherapy devices
KR102715288B1 (ko) 2018-04-02 2024-10-11 알파 타우 메디컬 리미티드 방사성 핵종의 제어된 방출
WO2021013978A1 (en) 2019-07-25 2021-01-28 Bayer As Targeted radiopharmaceuticals for the diagnosis and treatment of prostate cancer
CN114902350A (zh) 2019-12-05 2022-08-12 塞控斯公司 生产高纯度212Pb
EP4262888A4 (en) 2020-12-16 2024-10-30 Alpha Tau Medical Ltd. DIFFUSION ALPHA-EMITTER RADIATION THERAPY WITH IMPROVED BETA TREATMENT

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310506A (en) * 1979-02-22 1982-01-12 California Institute Of Technology Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species
IE58659B1 (en) * 1984-10-22 1993-11-03 Vestar Inc Use of a micellular particle composition encapsulating a chemotherapeutic agent for intravenous targeting to tumors
JP2710847B2 (ja) * 1987-11-04 1998-02-10 ネクスター・フアーマシユーテイカルズ・インコーポレイテツド 中性子捕獲療法剤およびその製法
US5527528A (en) * 1989-10-20 1996-06-18 Sequus Pharmaceuticals, Inc. Solid-tumor treatment method
CA2134239C (en) * 1992-06-09 2004-11-23 Donald B. Axworthy Pretargeting methods and compounds
GB9420390D0 (en) * 1994-10-10 1994-11-23 Nycomed Salutar Inc Liposomal agents
DE69937797D1 (de) * 1998-05-26 2008-01-31 Sloan Kettering Inst Cancer Alpha-emittierende konstrukte sowie deren verwendung

Also Published As

Publication number Publication date
EA005624B1 (ru) 2005-04-28
ZA200206500B (en) 2003-08-14
CN100350981C (zh) 2007-11-28
EP1257299B1 (en) 2005-07-27
CN1404402A (zh) 2003-03-19
NZ520848A (en) 2005-02-25
UA73160C2 (uk) 2005-06-15
CZ20023164A3 (cs) 2003-04-16
NO20000855D0 (no) 2000-02-21
JP2003522808A (ja) 2003-07-29
DE60112251D1 (de) 2005-09-01
EP1257299A2 (en) 2002-11-20
US6592843B2 (en) 2003-07-15
CA2400994A1 (en) 2001-08-23
EP1257299B9 (en) 2005-11-30
AU3782701A (en) 2001-08-27
EA200200793A1 (ru) 2003-02-27
JP4933712B2 (ja) 2012-05-16
ATE300316T1 (de) 2005-08-15
NO312708B1 (no) 2002-06-24
BR0108572A (pt) 2002-11-19
DK1257299T3 (da) 2005-11-21
WO2001060417A2 (en) 2001-08-23
KR100822566B1 (ko) 2008-04-16
NO20000855L (no) 2001-08-22
AU2001237827B2 (en) 2007-11-22
DE60112251T2 (de) 2006-03-30
ES2247069T3 (es) 2006-03-01
CA2400994C (en) 2009-07-07
KR20020092963A (ko) 2002-12-12
PL201398B1 (pl) 2009-04-30
PL358541A1 (en) 2004-08-09
WO2001060417A3 (en) 2002-02-07
AU2001237827B8 (en) 2001-08-27
CZ299032B6 (cs) 2008-04-09
US20010048914A1 (en) 2001-12-06

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