SG11201910176PA - Polymer coatings for brachytherapy devices - Google Patents
Polymer coatings for brachytherapy devicesInfo
- Publication number
- SG11201910176PA SG11201910176PA SG11201910176PA SG11201910176PA SG 11201910176P A SG11201910176P A SG 11201910176PA SG 11201910176P A SG11201910176P A SG 11201910176PA SG 11201910176P A SG11201910176P A SG 11201910176PA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- street
- tel aviv
- pct
- radionuclide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
- A61K51/1289—Devices or containers for impregnation, for emanation, e.g. bottles or jars for radioactive water for use in radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1027—Interstitial radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
- G21G4/04—Radioactive sources other than neutron sources
- G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
- G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/02—Methods for coating medical devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/08—Coatings comprising two or more layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N2005/1019—Sources therefor
- A61N2005/1025—Wires
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D1/00—Processes for applying liquids or other fluent materials
- B05D1/18—Processes for applying liquids or other fluent materials performed by dipping
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D7/00—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
- B05D7/50—Multilayers
- B05D7/52—Two layers
- B05D7/54—No clear coat specified
- B05D7/548—No curing step for the last layer
- B05D7/5483—No curing step for any layer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Dispersion Chemistry (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Laminated Bodies (AREA)
Abstract
TO 22 FIG. 1 W O 20 18/ 207 105 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 15 November 2018 (15.11.2018) WIPO I PCT IiiimmomiolollmonolooloionmoionomovoimIE (10) International Publication Number WO 2018/207105 Al (51) International Patent Classification: A61N 5/10 (2006.01) C23C 14/06 (2006.01) A61K 51/12 (2006.01) C23C 14/48 (2006.01) A61K 9/00 (2006.01) (21) International Application Number: PCT/IB2018/053213 (22) International Filing Date: 09 May 2018 (09.05.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/504,800 11 May 2017 (11.05.2017) US (71) Applicant: ALPHA TAU MEDICAL LTD. [IL/IL]; School of Physics, Tel Aviv University, P.O. Box 39040, 6997801 Tel Aviv (IL). (72) Inventors: KELSON, Itzhak; 94 Dizengoff Street, 6439606 Tel Aviv (IL). KEISARI, Yona; 8 Hagaon Eliyahu Street, 5236477 Ramat Gan (IL). SCHMIDT, Michael; 7 Eucalyptus Street, 4453507 Kfar Saba (IL). BERKOWITZ, Avia; 34/8 Hasida Street, 7169334 Modiin (IL). MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) Agent: D. KLIGLER I. P. SERVICES LTD.; P. O. Box 57651, 61576 Tel Aviv (IL). Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, (54) Title: POLYMER COATINGS FOR BRACHYTHERAPY DEVICES (57) : Described embodiments include an apparatus (20, 21), which includes a support (22), including an outer surface (24) and config- ured for insertion into a body of a subject. The apparatus further includes multiple atoms (26) of a radionuclide, which radioactively decays to pro- duce a daughter radionuclide, coupled to the outer surface, and a layer (28, 33) of a polymer, which is permeable to the daughter radionuclide, that covers the atoms. Other embodiments are also described.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762504800P | 2017-05-11 | 2017-05-11 | |
PCT/IB2018/053213 WO2018207105A1 (en) | 2017-05-11 | 2018-05-09 | Polymer coatings for brachytherapy devices |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201910176PA true SG11201910176PA (en) | 2019-11-28 |
Family
ID=64104434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201910176P SG11201910176PA (en) | 2017-05-11 | 2018-05-09 | Polymer coatings for brachytherapy devices |
Country Status (12)
Country | Link |
---|---|
US (2) | US11529432B2 (en) |
EP (1) | EP3621692A4 (en) |
JP (2) | JP7232489B2 (en) |
KR (1) | KR102560243B1 (en) |
CN (1) | CN110603076A (en) |
AU (1) | AU2018265386B2 (en) |
CA (1) | CA3059534A1 (en) |
MX (1) | MX2019013346A (en) |
RU (1) | RU2763750C2 (en) |
SG (1) | SG11201910176PA (en) |
WO (1) | WO2018207105A1 (en) |
ZA (1) | ZA201906581B (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9821174B1 (en) | 2015-02-06 | 2017-11-21 | Gammatile Llc | Radioactive implant planning system and placement guide system |
US10888710B1 (en) | 2016-11-29 | 2021-01-12 | Gt Medical Technologies, Inc. | Transparent loading apparatus |
JP2021519126A (en) | 2018-04-02 | 2021-08-10 | アルファ タウ メディカル リミテッド | Controlled release of radionuclides |
AU2021400142A1 (en) | 2020-12-16 | 2023-06-22 | Alpha Tau Medical Ltd. | Diffusing alpha-emitters radiation therapy with enhanced beta treatment |
US11964168B2 (en) | 2021-06-10 | 2024-04-23 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for prostate cancer |
US20220395702A1 (en) | 2021-06-10 | 2022-12-15 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for glioblastoma |
US20220395701A1 (en) | 2021-06-10 | 2022-12-15 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for pancreatic cancer |
US20220395703A1 (en) | 2021-06-10 | 2022-12-15 | Alpha Tau Medical Ltd. | Activity levels for diffusing alpha-emitter radiation therapy |
CN113908346B (en) * | 2021-11-12 | 2023-03-07 | 上海交通大学 | Radioactive lumen stent and preparation method thereof |
US20230335315A1 (en) * | 2022-04-14 | 2023-10-19 | Zense-Life Inc. | Coating a working wire for a continuous biological sensor |
Family Cites Families (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1810528A1 (en) | 1968-11-23 | 1970-06-04 | Messerschmitt Boelkow Blohm | Radionuclide generator |
US3811426A (en) | 1973-05-21 | 1974-05-21 | Atomic Energy Commission | Method and apparatus for the in-vessel radiation treatment of blood |
US4107283A (en) | 1976-07-19 | 1978-08-15 | New England Nuclear Corporation | Tracer for circulation determinations |
DE3241589A1 (en) | 1982-11-10 | 1984-05-17 | Pfaudler-Werke Ag, 6830 Schwetzingen | IMPLANTS AND METHOD FOR THE PRODUCTION THEREOF |
US4697575A (en) | 1984-11-21 | 1987-10-06 | Henry Ford Hospital | Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member |
US4976680A (en) | 1988-10-07 | 1990-12-11 | Hayman Michael H | Apparatus for in situ radiotherapy |
US6099457A (en) | 1990-08-13 | 2000-08-08 | Endotech, Inc. | Endocurietherapy |
US5342283A (en) | 1990-08-13 | 1994-08-30 | Good Roger R | Endocurietherapy |
US5531662A (en) | 1990-12-17 | 1996-07-02 | Microwave Medical Systems, Inc. | Dual mode microwave/ionizing probe |
JP3406661B2 (en) | 1993-12-06 | 2003-05-12 | 日本メジフィジックス株式会社 | Syringe barrel sheath |
RU2089143C1 (en) | 1994-03-02 | 1997-09-10 | Московский научно-исследовательский институт глазных болезней им.Гельмгольца | Method for brachytherapy of intraocular tumors |
US6589502B1 (en) * | 1995-11-27 | 2003-07-08 | International Brachytherapy S.A. | Radioisotope dispersed in a matrix for brachytherapy |
US5713828A (en) | 1995-11-27 | 1998-02-03 | International Brachytherapy S.A | Hollow-tube brachytherapy device |
CA2248076A1 (en) | 1996-03-11 | 1997-09-18 | Richard D. Leavitt | Polymeric delivery of radionuclides and radiopharmaceuticals |
DE19724230C1 (en) | 1997-04-30 | 1998-11-26 | Schering Ag | Applying radioactive coating to stent that has been treated with adhesion promoter |
WO1999002194A1 (en) | 1997-07-11 | 1999-01-21 | Innerdyne, Inc. | Methods and systems for preparing and sealing radiation delivery structures |
US6254552B1 (en) * | 1997-10-03 | 2001-07-03 | E.I. Du Pont De Nemours And Company | Intra-coronary radiation devices containing Ce-144 or Ru-106 |
US6419621B1 (en) | 1997-10-24 | 2002-07-16 | Radiomed Corporation | Coiled brachytherapy device |
US6030333A (en) | 1997-10-24 | 2000-02-29 | Radiomed Corporation | Implantable radiotherapy device |
US6394945B1 (en) | 1997-12-22 | 2002-05-28 | Mds (Canada), Inc. | Radioactively coated devices |
US6077413A (en) | 1998-02-06 | 2000-06-20 | The Cleveland Clinic Foundation | Method of making a radioactive stent |
US6060036A (en) | 1998-02-09 | 2000-05-09 | Implant Sciences Corporation | Radioactive seed implants |
EP1054707B1 (en) | 1998-02-12 | 2005-04-27 | Robert Robertson | Encapsulated low-energy brachytherapy sources |
US20020131935A1 (en) | 1998-04-10 | 2002-09-19 | Fisher Darrell R. | Fibrin carrier compound for treatment of disease |
WO2000006243A2 (en) | 1998-07-28 | 2000-02-10 | Innerdyne, Inc. | Absorbable brachytherapy and chemotherapy delivery devices and methods |
US6676595B1 (en) | 1998-08-24 | 2004-01-13 | Varian Medical Systems Technologies, Inc. | Radioactive medical implant and method of manufacturing |
JP2002530128A (en) | 1998-11-18 | 2002-09-17 | ラジオバスキュラー、システムズ、リミテッド、ライアビリティ、カンパニー | Radioactive coating solution, method and substrate |
US20020077520A1 (en) | 1998-11-18 | 2002-06-20 | Jerome Segal | Device and method for dilating and irradiating a vascular segment or body passageway |
NO310544B1 (en) | 1999-01-04 | 2001-07-23 | Algeta As | Preparation and use of radium-223 for the preparation of preparations and kits for the treatment of calcified tissue for palliation, bone cancer therapy and / or bone surface treatment |
US6224536B1 (en) | 1999-02-08 | 2001-05-01 | Advanced Cardiovascular Systems | Method for delivering radiation therapy to an intravascular site in a body |
US6391911B1 (en) | 1999-02-26 | 2002-05-21 | Robert E. Bases | Coadministration of lucanthone and radiation for treatment of cancer |
US6059714A (en) | 1999-03-26 | 2000-05-09 | Implant Sciences Corporation | Radioactive medical devices |
US6392068B1 (en) | 1999-07-07 | 2002-05-21 | The University Of Georgia Research Foundation, Inc. | Carborane containing cholesterol, a new type of molecule for targeted boron drug delivery |
AU1374601A (en) | 1999-11-12 | 2001-05-30 | Angiotech International Ag | Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors |
US6575888B2 (en) | 2000-01-25 | 2003-06-10 | Biosurface Engineering Technologies, Inc. | Bioabsorbable brachytherapy device |
NO312708B1 (en) | 2000-02-21 | 2002-06-24 | Anticancer Therapeutic Inv Sa | Radioactive liposomes for therapy |
NO313180B1 (en) | 2000-07-04 | 2002-08-26 | Anticancer Therapeutic Inv Sa | Visiting alpha particles emitting radiopharmaceuticals |
CA2320557A1 (en) | 2000-09-25 | 2002-03-25 | Michelangelo Delfino | Radioactive medical implant and method of manufacturing |
AU2001297657A1 (en) | 2000-11-16 | 2002-09-12 | Microspherix Llc | Polymeric imagable brachytherapy seed |
EP1545705A4 (en) | 2000-11-16 | 2010-04-28 | Microspherix Llc | Flexible and/or elastic brachytherapy seed or strand |
US6638205B1 (en) * | 2000-11-17 | 2003-10-28 | Mds (Canada) Inc. | Radioactive medical device for radiation therapy |
RU2174015C1 (en) | 2000-11-21 | 2001-09-27 | Кешелава Виктор Владимирович | Method for producing preparation and treating oncologic diseases |
EP1232770A1 (en) * | 2001-02-15 | 2002-08-21 | AEA Technology QSA GmbH | Radioactive capsule seed |
EP1232769A1 (en) | 2001-02-15 | 2002-08-21 | AEA Technology QSA GmbH | Capsule seed manufactured with Pd-103 |
WO2002078785A2 (en) | 2001-04-02 | 2002-10-10 | Radiovascular, Inc. | A brachytherapy device and method of use |
RU2182022C1 (en) | 2001-05-24 | 2002-05-10 | Российская медицинская академия последипломного образования МЗ РФ | Method for treating oncological diseases of the thyroid gland |
US6723052B2 (en) | 2001-06-07 | 2004-04-20 | Stanley L. Mills | Echogenic medical device |
US20030118649A1 (en) | 2001-10-04 | 2003-06-26 | Jinming Gao | Drug delivery devices and methods |
AU2003226408B2 (en) | 2002-04-15 | 2007-06-14 | Sloan-Kettering Institute For Cancer Research | Combination therapy for the treatment of cancer |
JP4987232B2 (en) * | 2002-11-18 | 2012-07-25 | ラットガーズ,ザ・ステート・ユニバーシティ・オブ・ニュージャージー | Medical devices using new polymers |
US20050222013A1 (en) | 2003-01-16 | 2005-10-06 | Georgetown University | Methods for the use of inhibitors of histone deacetylase as synergistic agents in cancer therapy |
US20060039858A1 (en) | 2003-02-11 | 2006-02-23 | Ekaterina Dadachova | Radiolabeled antibodies and peptides for treatment of tumors |
US20060142853A1 (en) | 2003-04-08 | 2006-06-29 | Xingwu Wang | Coated substrate assembly |
GB0308731D0 (en) | 2003-04-15 | 2003-05-21 | Anticancer Therapeutic Inv Sa | Method of radiotherapy |
EP2060274B1 (en) | 2003-04-30 | 2014-03-26 | Ramot at Tel-Aviv University Ltd. | Method and device for radiotherapy |
US7922646B2 (en) | 2003-08-20 | 2011-04-12 | International Brachytherapy, S.A. | Plastic brachytherapy sources |
US20050159809A1 (en) | 2004-01-21 | 2005-07-21 | Medtronic Vascular, Inc. | Implantable medical devices for treating or preventing restenosis |
WO2006003123A2 (en) | 2004-06-25 | 2006-01-12 | The European Community, Represented By The European Commission | Radionuclides for medical use |
US20060014938A1 (en) | 2004-07-14 | 2006-01-19 | Groman Ernest V | Stable aqueous colloidal lanthanide oxides |
DE602005020642D1 (en) | 2004-08-13 | 2010-05-27 | Setagon Inc | METHOD OF MANUFACTURING MEDICINE PRODUCTS WITH NANOPOROUS LAYERS |
GB0423565D0 (en) | 2004-10-22 | 2004-11-24 | Algeta As | Formulation |
WO2006110889A2 (en) | 2005-04-11 | 2006-10-19 | The Board Of Trustees Of The Leland Stanford Junior University | Multi-layer structure having a predetermined layer pattern including an agent |
CA2615589A1 (en) * | 2005-07-26 | 2007-02-01 | Ramot At Tel Aviv University Ltd. | A radioactive surface source and a method for producing the same |
US7862496B2 (en) | 2005-11-10 | 2011-01-04 | Cianna Medical, Inc. | Brachytherapy apparatus and methods for using them |
US20080249398A1 (en) | 2007-04-09 | 2008-10-09 | Harder George Fred | Hybrid Source Containing Multi-Radionuclides for Use in Radiation Therapy |
US20100015042A1 (en) | 2008-07-03 | 2010-01-21 | Ramot At Tel Aviv University Ltd. | Combine radiation therapy and chemotherapy for treating cancer |
US8821364B2 (en) * | 2008-09-02 | 2014-09-02 | Battelle Memorial Institute | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
US8764619B2 (en) | 2009-04-21 | 2014-07-01 | Breast Microseed Llc | Brachytherapy fiducial needle fixation system and method |
WO2011018792A1 (en) | 2009-08-12 | 2011-02-17 | Soreq NRC | Brachytherapy radioactive seeds compositions and methods for producing them |
WO2012066498A1 (en) | 2010-11-18 | 2012-05-24 | Northern Oncology (Pty) Ltd | Brachytherapy seed, methodology and calculating dose of brachytherapy and method of treatment |
CN103596622A (en) | 2011-06-01 | 2014-02-19 | 核通运营有限公司 | Brachytherapy source assembly |
US20140296612A1 (en) | 2013-03-26 | 2014-10-02 | David Schwartz | Brachytherapy Assist Device |
US9951399B2 (en) | 2014-04-09 | 2018-04-24 | Los Alamos National Security, Llc | Separation of protactinum, actinium, and other radionuclides from proton irradiated thorium target |
US9433690B1 (en) | 2015-02-26 | 2016-09-06 | Sciencons AS | Radiopharmaceutical solutions with advantageous properties |
MX2017016217A (en) | 2015-06-18 | 2018-04-24 | Acuitybio Corp | Implantable drug delivery compositions and methods of use thereof. |
RU2606108C2 (en) * | 2015-11-02 | 2017-01-10 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский радиологический центр" Министерства здравоохранения Российской Федерации (ФГБУ "НМИРЦ" Минздрава России) | Method of brachytherapy for localised prostate cancer |
JP2021519126A (en) * | 2018-04-02 | 2021-08-10 | アルファ タウ メディカル リミテッド | Controlled release of radionuclides |
-
2018
- 2018-05-09 MX MX2019013346A patent/MX2019013346A/en unknown
- 2018-05-09 CA CA3059534A patent/CA3059534A1/en active Pending
- 2018-05-09 JP JP2019557389A patent/JP7232489B2/en active Active
- 2018-05-09 WO PCT/IB2018/053213 patent/WO2018207105A1/en unknown
- 2018-05-09 CN CN201880029827.1A patent/CN110603076A/en active Pending
- 2018-05-09 EP EP18797701.2A patent/EP3621692A4/en active Pending
- 2018-05-09 US US16/610,507 patent/US11529432B2/en active Active
- 2018-05-09 SG SG11201910176P patent/SG11201910176PA/en unknown
- 2018-05-09 RU RU2019139620A patent/RU2763750C2/en active
- 2018-05-09 AU AU2018265386A patent/AU2018265386B2/en active Active
- 2018-05-09 KR KR1020197033304A patent/KR102560243B1/en active IP Right Grant
-
2019
- 2019-10-07 ZA ZA2019/06581A patent/ZA201906581B/en unknown
-
2022
- 2022-09-20 US US17/948,280 patent/US20230014526A1/en active Pending
-
2023
- 2023-02-07 JP JP2023017195A patent/JP2023055923A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP7232489B2 (en) | 2023-03-03 |
AU2018265386A1 (en) | 2019-10-31 |
US11529432B2 (en) | 2022-12-20 |
AU2018265386B2 (en) | 2020-07-23 |
RU2019139620A (en) | 2021-06-11 |
US20230014526A1 (en) | 2023-01-19 |
KR102560243B1 (en) | 2023-07-27 |
CA3059534A1 (en) | 2018-11-15 |
WO2018207105A1 (en) | 2018-11-15 |
US20210154340A1 (en) | 2021-05-27 |
JP2020519322A (en) | 2020-07-02 |
EP3621692A1 (en) | 2020-03-18 |
KR20200007816A (en) | 2020-01-22 |
MX2019013346A (en) | 2020-01-20 |
JP2023055923A (en) | 2023-04-18 |
RU2763750C2 (en) | 2022-01-10 |
CN110603076A (en) | 2019-12-20 |
RU2019139620A3 (en) | 2021-07-01 |
EP3621692A4 (en) | 2021-01-13 |
ZA201906581B (en) | 2021-01-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG11201910176PA (en) | Polymer coatings for brachytherapy devices | |
SG11201909949XA (en) | Targeted immunotolerance | |
SG11201909168VA (en) | Combination comprising a ppar agonist such as elafibranor and an acetyl-coa carboxylase (acc) inhibitor | |
SG11201900480YA (en) | Anti-tim-3 antibodies | |
SG11201805186VA (en) | Compositions and methods for immune cell modulation in adoptive immunotherapies | |
SG11201806624XA (en) | Deposition of molybdenum thin films using a molybdenum carbonyl precursor | |
SG11201903857UA (en) | Antibodies to pd-1 and uses thereof | |
SG11201808622SA (en) | Chimeric receptors to flt3 and methods of use thereof | |
SG11201811564QA (en) | Methods of treating ovarian cancer | |
SG11201808125RA (en) | Methods for solid tumor treatment | |
SG11201805311XA (en) | Method of treating a mammal, including human, against cancer using methionine and asparagine depletion | |
SG11201811095UA (en) | Multi-level storage in ferroelectric memory | |
SG11201907673YA (en) | Pharmaceutical compositions for combination therapy | |
SG11201805828YA (en) | Method of treating c3 glomerulopathy | |
SG11201803834UA (en) | Methods for treating conditions associated with masp-2 dependent complement activation | |
SG11201806825RA (en) | A data source system agnostic fact category partitioned information repository and methods for the insertion and retrieval of data using the information repository | |
SG11201408810TA (en) | Methods of treating arthritis | |
SG11201910195WA (en) | Methods for trapping and barcoding discrete biological units in hydrogel | |
SG11201808106YA (en) | Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation | |
SG11201909064RA (en) | Combination of an anti-pd-l1 antibody and a dna-pk inhibitor for the treatment of cancer | |
SG11201808686VA (en) | Synthesis of indazoles | |
SG11201901228QA (en) | Chromatography method for quantifying a non-ionic surfactant in a composition comprising the non-ionic surfactant and a polypeptide | |
SG11201906973TA (en) | Multiple transgene recombinant adenovirus | |
SG11201903786UA (en) | Farnesyltransferase inhibitors for use in methods of treating cancer | |
SG11201906987RA (en) | Combination of a ppar agonist with a fxr agonist |