NO312325B1 - Fremgangsmåte for behandling av tobakk for å redusere innholdet av nitrosamin og produkter som fremstilles derved - Google Patents
Fremgangsmåte for behandling av tobakk for å redusere innholdet av nitrosamin og produkter som fremstilles derved Download PDFInfo
- Publication number
- NO312325B1 NO312325B1 NO19996314A NO996314A NO312325B1 NO 312325 B1 NO312325 B1 NO 312325B1 NO 19996314 A NO19996314 A NO 19996314A NO 996314 A NO996314 A NO 996314A NO 312325 B1 NO312325 B1 NO 312325B1
- Authority
- NO
- Norway
- Prior art keywords
- tobacco
- approx
- radiation
- content
- leaves
- Prior art date
Links
- 235000002637 Nicotiana tabacum Nutrition 0.000 title claims description 343
- 241000208125 Nicotiana Species 0.000 title claims description 327
- 238000000034 method Methods 0.000 title claims description 101
- XKLJHFLUAHKGGU-UHFFFAOYSA-N nitrous amide Chemical compound ON=N XKLJHFLUAHKGGU-UHFFFAOYSA-N 0.000 title claims description 45
- 230000008569 process Effects 0.000 title description 29
- 230000005855 radiation Effects 0.000 claims description 102
- 235000019505 tobacco product Nutrition 0.000 claims description 72
- 230000015572 biosynthetic process Effects 0.000 claims description 56
- 150000004005 nitrosamines Chemical class 0.000 claims description 47
- FLAQQSHRLBFIEZ-UHFFFAOYSA-N N-Methyl-N-nitroso-4-oxo-4-(3-pyridyl)butyl amine Chemical compound O=NN(C)CCCC(=O)C1=CC=CN=C1 FLAQQSHRLBFIEZ-UHFFFAOYSA-N 0.000 claims description 39
- 238000001035 drying Methods 0.000 claims description 32
- 230000000391 smoking effect Effects 0.000 claims description 32
- 238000003306 harvesting Methods 0.000 claims description 30
- 239000000779 smoke Substances 0.000 claims description 30
- 235000019504 cigarettes Nutrition 0.000 claims description 24
- 238000009825 accumulation Methods 0.000 claims description 18
- 238000004383 yellowing Methods 0.000 claims description 18
- 230000002829 reductive effect Effects 0.000 claims description 17
- 244000061176 Nicotiana tabacum Species 0.000 claims description 16
- 241000196324 Embryophyta Species 0.000 claims description 15
- ZJOFAFWTOKDIFH-JTQLQIEISA-N 3-[(2s)-1-nitroso-3,6-dihydro-2h-pyridin-2-yl]pyridine Chemical compound O=NN1CC=CC[C@H]1C1=CC=CN=C1 ZJOFAFWTOKDIFH-JTQLQIEISA-N 0.000 claims description 14
- BXYPVKMROLGXJI-JTQLQIEISA-N 3-[(2s)-1-nitrosopiperidin-2-yl]pyridine Chemical compound O=NN1CCCC[C@H]1C1=CC=CN=C1 BXYPVKMROLGXJI-JTQLQIEISA-N 0.000 claims description 13
- 238000010894 electron beam technology Methods 0.000 claims description 12
- 238000003825 pressing Methods 0.000 claims description 12
- 238000001228 spectrum Methods 0.000 claims description 11
- XKABJYQDMJTNGQ-VIFPVBQESA-N n-nitrosonornicotine Chemical compound O=NN1CCC[C@H]1C1=CC=CN=C1 XKABJYQDMJTNGQ-VIFPVBQESA-N 0.000 claims description 10
- 229940112822 chewing gum Drugs 0.000 claims description 8
- 235000015218 chewing gum Nutrition 0.000 claims description 8
- 235000019506 cigar Nutrition 0.000 claims description 8
- 239000007937 lozenge Substances 0.000 claims description 7
- UPAPMNCQXRTGHN-UHFFFAOYSA-N 4-(nitrosomethylamino)-1-pyridin-3-ylbutan-1-one Chemical compound O=NCNCCCC(=O)C1=CC=CN=C1 UPAPMNCQXRTGHN-UHFFFAOYSA-N 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 5
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- 238000004321 preservation Methods 0.000 description 51
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 18
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 15
- 238000010438 heat treatment Methods 0.000 description 13
- 210000004027 cell Anatomy 0.000 description 12
- FFRBMBIXVSCUFS-UHFFFAOYSA-N 2,4-dinitro-1-naphthol Chemical compound C1=CC=C2C(O)=C([N+]([O-])=O)C=C([N+]([O-])=O)C2=C1 FFRBMBIXVSCUFS-UHFFFAOYSA-N 0.000 description 10
- 241001301450 Crocidium multicaule Species 0.000 description 10
- MTXSIJUGVMTTMU-JTQLQIEISA-N (S)-anabasine Chemical compound N1CCCC[C@H]1C1=CC=CN=C1 MTXSIJUGVMTTMU-JTQLQIEISA-N 0.000 description 8
- 239000013068 control sample Substances 0.000 description 8
- 230000000694 effects Effects 0.000 description 8
- SOPPBXUYQGUQHE-JTQLQIEISA-N Anatabine Chemical compound C1C=CCN[C@@H]1C1=CC=CN=C1 SOPPBXUYQGUQHE-JTQLQIEISA-N 0.000 description 7
- 231100000357 carcinogen Toxicity 0.000 description 7
- 239000003183 carcinogenic agent Substances 0.000 description 7
- 230000036961 partial effect Effects 0.000 description 7
- 230000009467 reduction Effects 0.000 description 7
- 238000012545 processing Methods 0.000 description 6
- 229910002651 NO3 Inorganic materials 0.000 description 5
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 5
- 229930013930 alkaloid Natural products 0.000 description 5
- 238000005520 cutting process Methods 0.000 description 5
- 230000007246 mechanism Effects 0.000 description 5
- 230000000813 microbial effect Effects 0.000 description 5
- 244000005700 microbiome Species 0.000 description 5
- 230000032258 transport Effects 0.000 description 5
- 241000366676 Justicia pectoralis Species 0.000 description 4
- 230000000711 cancerogenic effect Effects 0.000 description 4
- 229930002875 chlorophyll Natural products 0.000 description 4
- 235000019804 chlorophyll Nutrition 0.000 description 4
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
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- 239000000126 substance Substances 0.000 description 4
- 210000003462 vein Anatomy 0.000 description 4
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 3
- 231100000315 carcinogenic Toxicity 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 238000011835 investigation Methods 0.000 description 3
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 3
- 229960002715 nicotine Drugs 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- MYKUKUCHPMASKF-VIFPVBQESA-N (S)-nornicotine Chemical compound C1CCN[C@@H]1C1=CC=CN=C1 MYKUKUCHPMASKF-VIFPVBQESA-N 0.000 description 2
- SOPPBXUYQGUQHE-UHFFFAOYSA-N Anatabine Natural products C1C=CCNC1C1=CC=CN=C1 SOPPBXUYQGUQHE-UHFFFAOYSA-N 0.000 description 2
- MYKUKUCHPMASKF-UHFFFAOYSA-N Nornicotine Natural products C1CCNC1C1=CC=CN=C1 MYKUKUCHPMASKF-UHFFFAOYSA-N 0.000 description 2
- 150000001412 amines Chemical class 0.000 description 2
- 229930014345 anabasine Natural products 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
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- 238000006243 chemical reaction Methods 0.000 description 2
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- 238000004108 freeze drying Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 150000002826 nitrites Chemical class 0.000 description 2
- 230000009935 nitrosation Effects 0.000 description 2
- 238000007034 nitrosation reaction Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
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- 230000000717 retained effect Effects 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- OGRXKBUCZFFSTL-UHFFFAOYSA-N 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol Chemical compound O=NN(C)CCCC(O)C1=CC=CN=C1 OGRXKBUCZFFSTL-UHFFFAOYSA-N 0.000 description 1
- AYICONCBJGHAPX-UHFFFAOYSA-N 4-(nitrosomethylamino)-4-pyridin-3-ylbutanal Chemical compound O=CCCC(NCN=O)C1=CC=CN=C1 AYICONCBJGHAPX-UHFFFAOYSA-N 0.000 description 1
- NZSNJPDBPMIBSP-UHFFFAOYSA-N 4-[methyl(nitroso)amino]-4-pyridin-3-ylbutanoic acid Chemical compound OC(=O)CCC(N(N=O)C)C1=CC=CN=C1 NZSNJPDBPMIBSP-UHFFFAOYSA-N 0.000 description 1
- 208000032484 Accidental exposure to product Diseases 0.000 description 1
- 241000251169 Alopias vulpinus Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- LRHPLDYGYMQRHN-UHFFFAOYSA-N Butanol Natural products CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 1
- 229910000975 Carbon steel Inorganic materials 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 229920001875 Ebonite Polymers 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000208134 Nicotiana rustica Species 0.000 description 1
- 108090000913 Nitrate Reductases Proteins 0.000 description 1
- 108010025915 Nitrite Reductases Proteins 0.000 description 1
- JVMRPSJZNHXORP-UHFFFAOYSA-N ON=O.ON=O.ON=O.N Chemical compound ON=O.ON=O.ON=O.N JVMRPSJZNHXORP-UHFFFAOYSA-N 0.000 description 1
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- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
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- 150000001413 amino acids Chemical class 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
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- 229910052799 carbon Inorganic materials 0.000 description 1
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- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 235000015111 chews Nutrition 0.000 description 1
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- 235000013402 health food Nutrition 0.000 description 1
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- IIDMFFRDEFHWCJ-UHFFFAOYSA-N n-(4-hydroxy-1-pyridin-3-ylbutyl)-n-methylnitrous amide Chemical compound OCCCC(N(N=O)C)C1=CC=CN=C1 IIDMFFRDEFHWCJ-UHFFFAOYSA-N 0.000 description 1
- SFDJOSRHYKHMOK-UHFFFAOYSA-N nitramide Chemical class N[N+]([O-])=O SFDJOSRHYKHMOK-UHFFFAOYSA-N 0.000 description 1
- 235000020939 nutritional additive Nutrition 0.000 description 1
- 230000000771 oncological effect Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B3/00—Preparing tobacco in the factory
- A24B3/10—Roasting or cooling tobacco
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/22—Treatment of tobacco products or tobacco substitutes by application of electric or wave energy or particle radiation
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Manufacture Of Tobacco Products (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/879,905 US6135121A (en) | 1996-06-28 | 1997-06-20 | Tobacco products having reduced nitrosamine content |
US99804397A | 1997-12-23 | 1997-12-23 | |
PCT/US1998/012128 WO1998058555A1 (en) | 1997-06-20 | 1998-06-09 | Method of treating tobacco to reduce nitrosamine content, and products produced thereby |
Publications (3)
Publication Number | Publication Date |
---|---|
NO996314D0 NO996314D0 (no) | 1999-12-17 |
NO996314L NO996314L (no) | 2000-02-16 |
NO312325B1 true NO312325B1 (no) | 2002-04-29 |
Family
ID=27128558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19996314A NO312325B1 (no) | 1997-06-20 | 1999-12-17 | Fremgangsmåte for behandling av tobakk for å redusere innholdet av nitrosamin og produkter som fremstilles derved |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0991329A4 (xx) |
JP (1) | JP3996958B2 (xx) |
KR (1) | KR100458405B1 (xx) |
CN (1) | CN1135070C (xx) |
AP (1) | AP1524A (xx) |
AU (1) | AU736493B2 (xx) |
BR (1) | BR9810060A (xx) |
CA (1) | CA2294130C (xx) |
EA (1) | EA002448B1 (xx) |
EE (1) | EE9900590A (xx) |
GE (2) | GEP20022696B (xx) |
HU (1) | HUP0002532A3 (xx) |
IL (3) | IL154166A (xx) |
IS (1) | IS5311A (xx) |
NO (1) | NO312325B1 (xx) |
NZ (2) | NZ507948A (xx) |
OA (2) | OA11738A (xx) |
PL (1) | PL188860B1 (xx) |
TR (3) | TR199903160T2 (xx) |
WO (1) | WO1998058555A1 (xx) |
YU (1) | YU68799A (xx) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6805134B2 (en) | 1999-04-26 | 2004-10-19 | R. J. Reynolds Tobacco Company | Tobacco processing |
KR101281133B1 (ko) * | 2002-07-18 | 2013-07-02 | 유.에스. 스모크리스 토바코 컴퍼니 엘엘씨 | 담배 구성 성분의 감소 방법 |
JP3922985B2 (ja) * | 2002-08-22 | 2007-05-30 | 日本たばこ産業株式会社 | 空気乾燥種葉たばこの乾燥方法 |
WO2006038558A1 (ja) * | 2004-10-01 | 2006-04-13 | Japan Tobacco Inc. | バーレー種葉タバコの乾燥方法および該乾燥方法により乾燥したバーレー種葉タバコ |
CN101416770B (zh) * | 2008-11-25 | 2011-08-24 | 云南省烟草科学研究所 | 一种烟叶烘烤过程中防治黑蚂皮症状产生的烤烟烘烤工艺 |
US8151804B2 (en) * | 2008-12-23 | 2012-04-10 | Williams Jonnie R | Tobacco curing method |
US8539958B2 (en) | 2009-10-13 | 2013-09-24 | Philip Morris Usa Inc. | Oral moist smokeless tobacco products with net-structured gel coating and methods of making |
CN101933656B (zh) * | 2010-08-13 | 2012-10-03 | 川渝中烟工业有限责任公司 | 应用蒸汽爆破与微波辐射技术相结合改善烟梗品质的方法 |
RU2448586C1 (ru) * | 2010-12-23 | 2012-04-27 | Олег Иванович Квасенков | Способ выработки некурительного изделия из махорки |
RU2448587C1 (ru) * | 2010-12-27 | 2012-04-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
RU2448588C1 (ru) * | 2011-01-11 | 2012-04-27 | Олег Иванович Квасенков | Способ выработки некурительного изделия из махорки |
RU2443244C1 (ru) * | 2011-01-13 | 2012-02-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
RU2443362C1 (ru) * | 2011-01-20 | 2012-02-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
RU2443246C1 (ru) * | 2011-01-20 | 2012-02-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
RU2443363C1 (ru) * | 2011-01-20 | 2012-02-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
RU2443245C1 (ru) * | 2011-01-20 | 2012-02-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
RU2443364C1 (ru) * | 2011-01-27 | 2012-02-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
RU2443247C1 (ru) * | 2011-01-27 | 2012-02-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
RU2443365C1 (ru) * | 2011-02-01 | 2012-02-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
RU2443366C1 (ru) * | 2011-02-01 | 2012-02-27 | Олег Иванович Квасенков | Способ производства некурительного изделия из махорки |
RU2443332C1 (ru) * | 2011-02-10 | 2012-02-27 | Олег Иванович Квасенков | Способ выработки некурительного изделия из махорки |
RU2451471C1 (ru) * | 2011-02-18 | 2012-05-27 | Олег Иванович Квасенков | Способ получения некурительного изделия из махорки |
US9066538B2 (en) * | 2011-03-15 | 2015-06-30 | R.J. Reynolds Tobacco Company | Cured tobacco and method therefor |
RU2450759C1 (ru) * | 2011-05-11 | 2012-05-20 | Олег Иванович Квасенков | Способ получения некурительного изделия из табака |
RU2450760C1 (ru) * | 2011-05-11 | 2012-05-20 | Олег Иванович Квасенков | Способ получения некурительного изделия из табака |
RU2450761C1 (ru) * | 2011-05-17 | 2012-05-20 | Олег Иванович Квасенков | Способ выработки некурительного изделия из табака (варианты) |
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