NO303729B1 - 1-substituerte, 2-substituerte 1H-imidazo (4,5-c)-kinolin-4-aminer - Google Patents

1-substituerte, 2-substituerte 1H-imidazo (4,5-c)-kinolin-4-aminer

Info

Publication number
NO303729B1
NO303729B1 NO933069A NO933069A NO303729B1 NO 303729 B1 NO303729 B1 NO 303729B1 NO 933069 A NO933069 A NO 933069A NO 933069 A NO933069 A NO 933069A NO 303729 B1 NO303729 B1 NO 303729B1
Authority
NO
Norway
Prior art keywords
substituted
imidazo
amines
quinoline
hydroxyalkyl
Prior art date
Application number
NO933069A
Other languages
English (en)
Norwegian (no)
Other versions
NO933069L (no
NO933069D0 (no
Inventor
John F Gerster
Stephen L Crooks
Kyle J Lindstrom
Original Assignee
Minnesota Mining & Mfg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining & Mfg filed Critical Minnesota Mining & Mfg
Publication of NO933069D0 publication Critical patent/NO933069D0/no
Publication of NO933069L publication Critical patent/NO933069L/no
Publication of NO303729B1 publication Critical patent/NO303729B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Lubricants (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
NO933069A 1991-03-01 1993-08-27 1-substituerte, 2-substituerte 1H-imidazo (4,5-c)-kinolin-4-aminer NO303729B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66292691A 1991-03-01 1991-03-01
US68732691A 1991-04-18 1991-04-18
PCT/US1992/001305 WO1992015582A1 (en) 1991-03-01 1992-02-20 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES

Publications (3)

Publication Number Publication Date
NO933069D0 NO933069D0 (no) 1993-08-27
NO933069L NO933069L (no) 1993-11-01
NO303729B1 true NO303729B1 (no) 1998-08-24

Family

ID=27098631

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933069A NO303729B1 (no) 1991-03-01 1993-08-27 1-substituerte, 2-substituerte 1H-imidazo (4,5-c)-kinolin-4-aminer

Country Status (18)

Country Link
EP (2) EP0872478B1 (cs)
JP (1) JP2955019B2 (cs)
AT (2) ATE179711T1 (cs)
AU (2) AU658621B2 (cs)
CA (2) CA2104782C (cs)
CZ (1) CZ285050B6 (cs)
DE (2) DE69232878T2 (cs)
DK (2) DK0582581T3 (cs)
ES (2) ES2186034T3 (cs)
HU (5) HU222251B1 (cs)
IE (1) IE920605A1 (cs)
IL (2) IL101110A (cs)
NO (1) NO303729B1 (cs)
NZ (1) NZ241784A (cs)
PH (1) PH31614A (cs)
SG (2) SG70625A1 (cs)
UA (1) UA32546C2 (cs)
WO (1) WO1992015582A1 (cs)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
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US5266575A (en) * 1991-11-06 1993-11-30 Minnesota Mining And Manufacturing Company 2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
US5395937A (en) * 1993-01-29 1995-03-07 Minnesota Mining And Manufacturing Company Process for preparing quinoline amines
WO1995002597A1 (en) * 1993-07-15 1995-01-26 Minnesota Mining And Manufacturing Company IMIDAZO[4,5-c]PYRIDIN-4-AMINES
US5352784A (en) * 1993-07-15 1994-10-04 Minnesota Mining And Manufacturing Company Fused cycloalkylimidazopyridines
US5648516A (en) * 1994-07-20 1997-07-15 Minnesota Mining And Manufacturing Company Fused cycloalkylimidazopyridines
US5482936A (en) * 1995-01-12 1996-01-09 Minnesota Mining And Manufacturing Company Imidazo[4,5-C]quinoline amines
US6133547A (en) * 1996-09-05 2000-10-17 Medtronic, Inc. Distributed activator for a two-dimensional shape memory alloy
US5939090A (en) * 1996-12-03 1999-08-17 3M Innovative Properties Company Gel formulations for topical drug delivery
JPH10298181A (ja) * 1997-04-25 1998-11-10 Sumitomo Pharmaceut Co Ltd タイプ２ヘルパーｔ細胞選択的免疫応答抑制剤
SI1341791T1 (en) * 2000-12-08 2005-10-31 3M Innovative Properties Company Thioether substituted imidazoquinolines
US6664264B2 (en) * 2000-12-08 2003-12-16 3M Innovative Properties Company Thioether substituted imidazoquinolines
UA75622C2 (en) * 2000-12-08 2006-05-15 3M Innovative Properties Co Aryl ether substituted imidazoquinolines, pharmaceutical composition based thereon
GB0211649D0 (en) * 2002-05-21 2002-07-03 Novartis Ag Organic compounds
MXPA05000893A (es) * 2002-07-23 2005-09-30 Biogal Gyogyszergyar Preparacion de 1h-imidazo[4,5-c]quinolin-4-aminas a traves de compuestos intermedios 1h-imidazo [4,5-c] quinolin-4-ftalimida.
BRPI0414856A (pt) 2003-10-03 2006-11-21 3M Innovative Properties Co imidazoquinolinas alcóxi-substituìdas
MXPA06005910A (es) 2003-11-25 2006-08-23 3M Innovative Properties Co Sistemas de anillo imidazo sustituido y metodos.
US7884207B2 (en) * 2004-06-18 2011-02-08 3M Innovative Properties Company Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
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JP2008538550A (ja) 2005-04-01 2008-10-30 コーリー ファーマシューティカル グループ，インコーポレイテッド ウイルス感染および腫瘍性疾患を処置するためのサイトカイン生合成の調節因子としての１−置換ピラゾロ（３，４−ｃ）環状化合物
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ES2429170T3 (es) * 2005-11-04 2013-11-13 3M Innovative Properties Company 1H-Imidazoquinolinas sustituidas con hidroxilo y alcoxilo y métodos
CN102727885A (zh) 2005-11-04 2012-10-17 诺华疫苗和诊断有限公司 包含颗粒佐剂和免疫增强剂组合的流感疫苗
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AU2009227674C1 (en) 2008-03-18 2015-01-29 Seqirus UK Limited Improvements in preparation of influenza virus vaccine antigens
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CN102438650A (zh) 2009-03-06 2012-05-02 诺华有限公司 衣原体抗原
CN109248313B (zh) 2009-04-14 2023-01-17 葛兰素史密丝克莱恩生物有限公司 用于免疫接种以抵御金黄色葡萄球菌的组合物
BE1019643A3 (fr) 2009-04-27 2012-09-04 Novartis Ag Vaccins de protection contre la grippe.
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MX2012000734A (es) 2009-07-16 2012-01-27 Novartis Ag Inmunogenos destoxificados de escherichia coli.
GB0918392D0 (en) 2009-10-20 2009-12-02 Novartis Ag Diagnostic and therapeutic methods
GB0919690D0 (en) 2009-11-10 2009-12-23 Guy S And St Thomas S Nhs Foun compositions for immunising against staphylococcus aureus
WO2011084726A1 (en) * 2009-12-21 2011-07-14 3M Innovative Properties Company BIS [4-AMINO-2-(ETHOXYMETHYL)-1-(2-HYDROXY-2-METHYLPROPYL)-1H-IMIDAZO[4,5-c]QUINOLIN-5-IUM] 4-[(3-CARBOXYLATO-2-HYDROXYNAPHTHALEN-1-YL)METHYL]-3-HYDROXYNAPHTHALENE-2-CARBOXYLATE COMPOSITIONS AND METHODS
WO2011084725A1 (en) * 2009-12-21 2011-07-14 3M Innovative Properties Company 4-AMINO-2-(ETHOXYMETHYL)-1-(2-HYDROXY-2-METHYLPROPYL)-1H-IMIDAZO[4,5-c]QUINOLIN-5-IUM 1-HYDROXYNAPHTHALENE-2-CARBOXYLATE COMPOSITIONS AND METHODS
JP5781542B2 (ja) 2009-12-30 2015-09-24 ノバルティス アーゲー Ｅ．ｃｏｌｉキャリアタンパク質に結合体化した多糖免疫原
CN107080839A (zh) 2010-05-26 2017-08-22 西莱克塔生物科技公司 多价的合成纳米载体疫苗
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RU2722149C1 (ru) * 2015-09-14 2020-05-27 Пфайзер Инк. Новые производные имидазо[4,5-c] хинолинов и имидазо[4,5-c][1,5] нафтиридинов в качестве ингибиторов LRRK2
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JP7012668B2 (ja) 2016-06-12 2022-02-14 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト ジヒドロピリミジニルベンズアゼピンジカルボキサミド化合物
TWI674261B (zh) * 2017-02-17 2019-10-11 美商英能腫瘤免疫股份有限公司 Nlrp3 調節劑
ES2928723T3 (es) * 2017-05-19 2022-11-22 Superb Wisdom Ltd Derivados de Resiquimod
RU2020102453A (ru) * 2017-06-23 2021-07-23 Бирди Байофармасьютикалз, Инк. Фармацевтические композиции
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Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
IL73534A (en) * 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
CA1271477A (en) * 1983-11-18 1990-07-10 John F. Gerster 1h-imidazo[4,5-c]quinolin-4-amines
EP0385630B1 (en) * 1989-02-27 1996-11-27 Riker Laboratories, Inc. 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals

Also Published As

Publication number Publication date
HU9302457D0 (en) 1993-11-29
DK0582581T3 (da) 1999-11-08
AU2715795A (en) 1995-09-21
ES2186034T3 (es) 2003-05-01
CZ285050B6 (cs) 1999-05-12
NO933069L (no) 1993-11-01
IL101110A (en) 1995-12-08
HU222250B1 (hu) 2003-05-28
AU1566992A (en) 1992-10-06
EP0582581A1 (en) 1994-02-16
CA2104782C (en) 2001-08-07
DE69232878D1 (de) 2003-01-30
CA2104782A1 (en) 1992-09-02
CZ178893A3 (en) 1995-10-18
DE69229114D1 (de) 1999-06-10
IE920605A1 (en) 1992-09-09
IE990988A1 (en) 2000-12-13
HU9701089D0 (en) 1997-08-28
DE69229114T2 (de) 1999-11-04
IL114570A0 (en) 1995-11-27
PH31614A (en) 1999-01-12
UA32546C2 (uk) 2001-02-15
JP2955019B2 (ja) 1999-10-04
HU9701083D0 (en) 1997-08-28
SG70625A1 (en) 2000-02-22
DE69232878T2 (de) 2003-11-20
HU222247B1 (hu) 2003-05-28
HU211242A9 (en) 1995-11-28
CA2289219A1 (en) 1992-09-02
EP0872478A3 (en) 1998-11-04
ATE179711T1 (de) 1999-05-15
IL101110A0 (en) 1992-11-15
AU673309B2 (en) 1996-10-31
DK0872478T3 (da) 2003-03-31
HU222111B1 (hu) 2003-04-28
HU222251B1 (hu) 2003-05-28
HUT67026A (en) 1995-01-30
JPH06504789A (ja) 1994-06-02
HU9701084D0 (en) 1997-08-28
NO933069D0 (no) 1993-08-27
EP0872478B1 (en) 2002-12-18
SG46492A1 (en) 1998-02-20
IL114570A (en) 1996-10-31
CA2289219C (en) 2003-05-20
ES2131070T3 (es) 1999-07-16
AU658621B2 (en) 1995-04-27
WO1992015582A1 (en) 1992-09-17
EP0872478A2 (en) 1998-10-21
ATE229943T1 (de) 2003-01-15
NZ241784A (en) 1995-06-27
EP0582581B1 (en) 1999-05-06

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