NO303580B1 - FremgangsmÕte for fremstilling av CD4 polypeptidvariant, nukleinsyre, replikerbar vektor og rekombinant vertscelle - Google Patents
FremgangsmÕte for fremstilling av CD4 polypeptidvariant, nukleinsyre, replikerbar vektor og rekombinant vertscelle Download PDFInfo
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- NO303580B1 NO303580B1 NO901311A NO901311A NO303580B1 NO 303580 B1 NO303580 B1 NO 303580B1 NO 901311 A NO901311 A NO 901311A NO 901311 A NO901311 A NO 901311A NO 303580 B1 NO303580 B1 NO 303580B1
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Classifications
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10432987A | 1987-10-02 | 1987-10-02 | |
| US25078588A | 1988-09-28 | 1988-09-28 | |
| PCT/US1988/003414 WO1989002922A1 (en) | 1987-10-02 | 1988-10-03 | Adheson variants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO901311D0 NO901311D0 (no) | 1990-03-21 |
| NO901311L NO901311L (no) | 1990-03-21 |
| NO303580B1 true NO303580B1 (no) | 1998-08-03 |
Family
ID=26801413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO901311A NO303580B1 (no) | 1987-10-02 | 1990-03-21 | FremgangsmÕte for fremstilling av CD4 polypeptidvariant, nukleinsyre, replikerbar vektor og rekombinant vertscelle |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP0383799B2 (de) |
| JP (1) | JP2888529B2 (de) |
| AT (1) | ATE166387T1 (de) |
| CA (1) | CA1341427C (de) |
| DE (1) | DE3856189T3 (de) |
| DK (1) | DK175930B1 (de) |
| ES (1) | ES2121733T5 (de) |
| HK (1) | HK1010790A1 (de) |
| NO (1) | NO303580B1 (de) |
| NZ (1) | NZ226414A (de) |
| PT (1) | PT88641B (de) |
| WO (1) | WO1989002922A1 (de) |
Families Citing this family (168)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989001940A1 (en) * | 1987-09-04 | 1989-03-09 | Biogen, Inc. | Dna sequences, recombinant dna molecules and processes for producing soluble t4 proteins |
| IL87902A0 (en) * | 1987-10-08 | 1989-03-31 | Dana Farber Cancer Inst Inc | Soluble human cd4 fragments and applications thereof |
| PT89484B (pt) * | 1988-01-22 | 1994-03-31 | Gen Hospital Corp | Genes clonados codificadores de proteinas de fusao ig-cd4 e sua utilizacao |
| US6004781A (en) * | 1988-01-22 | 1999-12-21 | The General Hospital Corporation | Nucleic acid encoding Ig-CD4 fusion proteins |
| GB8824869D0 (en) * | 1988-10-24 | 1988-11-30 | Stevenson G T | Synthetic antibody |
| US5681566A (en) * | 1988-10-24 | 1997-10-28 | 3I Research Exploitation Limited | Antibody conjugates with two or more covalently linked FC regions |
| US5225538A (en) * | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| US5116964A (en) * | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US6406697B1 (en) | 1989-02-23 | 2002-06-18 | Genentech, Inc. | Hybrid immunoglobulins |
| WO1990010015A1 (en) * | 1989-02-23 | 1990-09-07 | Seragen, Inc. | Chimeric toxin |
| US6267964B1 (en) | 1989-08-01 | 2001-07-31 | Affibody Technology Sweden Ab | Stabilized protein or peptide conjugates able to bond albumin having extended biological half-lives |
| FR2650598B1 (fr) * | 1989-08-03 | 1994-06-03 | Rhone Poulenc Sante | Derives de l'albumine a fonction therapeutique |
| JPH05500611A (ja) * | 1989-08-23 | 1993-02-12 | ザ・ジェネラル・ホスピタル・コーポレーション | 非ヒト霊長類ｃｄ４ポリペプチド、グリコシル化可能なヒトｃｄ４分子、その断片、その融合タンパク質、その遺伝子配列および使用 |
| US5395760A (en) * | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| NZ235148A (en) | 1989-09-05 | 1991-12-23 | Immunex Corp | Tumour necrosis factor receptor protein and dna sequences |
| US6541610B1 (en) | 1989-09-05 | 2003-04-01 | Immunex Corporation | Fusion proteins comprising tumor necrosis factor receptor |
| US5945397A (en) * | 1989-09-05 | 1999-08-31 | Immunex Corporation | Purified p75 (type II) tumor necrosis factor receptor polypeptides |
| DK0417563T3 (da) * | 1989-09-12 | 2000-11-06 | Hoffmann La Roche | TNF-bindende proteiner |
| CA2065029A1 (en) * | 1989-09-14 | 1991-03-15 | Ellen S. Vitetta | Therapeutic compositions; methods for treatment of hiv infections |
| US5767072A (en) * | 1989-09-14 | 1998-06-16 | Board Of Regents, The University Of Texas System | Therapeutic compositions comprising a CD4 peptide and methods of treatment of HIV infections |
| US5116944A (en) * | 1989-12-29 | 1992-05-26 | Neorx Corporation | Conjugates having improved characteristics for in vivo administration |
| AU7217891A (en) * | 1990-02-13 | 1991-09-03 | Oxford Virology Plc | Therapeutic agents, and intermediates for the synthesis thereof |
| US5498538A (en) * | 1990-02-15 | 1996-03-12 | The University Of North Carolina At Chapel Hill | Totally synthetic affinity reagents |
| US5614612A (en) * | 1990-03-09 | 1997-03-25 | Haigwood; Nancy L. | Purified gp120 compositions retaining natural conformation |
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- 1988-10-03 JP JP63508520A patent/JP2888529B2/ja not_active Expired - Lifetime
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- 1988-10-03 ES ES88309194T patent/ES2121733T5/es not_active Expired - Lifetime
- 1988-10-03 DE DE3856189T patent/DE3856189T3/de not_active Expired - Lifetime
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- 1988-10-03 EP EP88309194A patent/EP0314317B2/de not_active Expired - Lifetime
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1990
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Also Published As
| Publication number | Publication date |
|---|---|
| EP0383799B1 (de) | 1998-05-20 |
| DK175930B1 (da) | 2005-07-11 |
| EP0383799B2 (de) | 2005-02-09 |
| JPH04502850A (ja) | 1992-05-28 |
| PT88641A (pt) | 1988-10-01 |
| EP0314317A1 (de) | 1989-05-03 |
| NO901311D0 (no) | 1990-03-21 |
| DK80590A (da) | 1990-05-30 |
| NO901311L (no) | 1990-03-21 |
| NZ226414A (en) | 1992-07-28 |
| DE3856189T2 (de) | 1998-11-05 |
| DE3856189T3 (de) | 2005-11-10 |
| ATE166387T1 (de) | 1998-06-15 |
| JP2888529B2 (ja) | 1999-05-10 |
| WO1989002922A1 (en) | 1989-04-06 |
| PT88641B (pt) | 1993-04-30 |
| ES2121733T5 (es) | 2005-10-16 |
| EP0314317B1 (de) | 1998-08-26 |
| ES2121733T3 (es) | 1998-12-16 |
| EP0314317B2 (de) | 2005-03-23 |
| HK1010790A1 (en) | 1999-06-25 |
| DE3856189D1 (de) | 1998-06-25 |
| DK80590D0 (da) | 1990-03-30 |
| EP0383799A1 (de) | 1990-08-29 |
| CA1341427C (en) | 2003-04-22 |
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