NO2907521T3 - - Google Patents

Info

Publication number
NO2907521T3
NO2907521T3 NO15157320A NO15157320A NO2907521T3 NO 2907521 T3 NO2907521 T3 NO 2907521T3 NO 15157320 A NO15157320 A NO 15157320A NO 15157320 A NO15157320 A NO 15157320A NO 2907521 T3 NO2907521 T3 NO 2907521T3
Authority
NO
Norway
Application number
NO15157320A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47428641&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO2907521(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of NO2907521T3 publication Critical patent/NO2907521T3/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO15157320A 2011-12-19 2012-12-19 NO2907521T3 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11194208 2011-12-19
EP12805695.9A EP2672984B1 (en) 2011-12-19 2012-12-19 Novel prongf mutants and uses thereof in the production of beta-ngf
EP15157320.1A EP2907521B1 (en) 2011-12-19 2012-12-19 Novel prongf mutants and uses thereof in the production of beta-ngf

Publications (1)

Publication Number Publication Date
NO2907521T3 true NO2907521T3 (no) 2018-04-21

Family

ID=47428641

Family Applications (1)

Application Number Title Priority Date Filing Date
NO15157320A NO2907521T3 (no) 2011-12-19 2012-12-19

Country Status (28)

Country Link
US (3) US9617322B2 (no)
EP (2) EP2672984B1 (no)
JP (4) JP6039146B2 (no)
KR (2) KR20160120788A (no)
CN (2) CN104203264B (no)
AU (1) AU2012357052B2 (no)
BR (1) BR112014014913B1 (no)
CA (1) CA2859262C (no)
CY (2) CY1117016T1 (no)
DK (2) DK2907521T3 (no)
EA (1) EA031333B1 (no)
ES (2) ES2657344T3 (no)
HK (1) HK1202055A1 (no)
HR (2) HRP20150900T1 (no)
HU (2) HUE027245T2 (no)
IL (1) IL233137A0 (no)
LT (1) LT2907521T (no)
MX (2) MX370861B (no)
NO (1) NO2907521T3 (no)
PL (2) PL2672984T3 (no)
PT (2) PT2907521T (no)
RS (2) RS56893B1 (no)
SG (2) SG10201605028VA (no)
SI (2) SI2672984T1 (no)
SM (1) SMT201500201B (no)
TR (1) TR201802360T4 (no)
WO (1) WO2013092776A1 (no)
ZA (1) ZA201403753B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2657344T3 (es) 2011-12-19 2018-03-02 Wacker Chemie Ag Nuevos mutantes de proNGF y usos de los mismos en la producción de beta-NGF
WO2015038582A2 (en) * 2013-09-11 2015-03-19 New York University Methods and compositions for treating bone diseases
EP3406259A1 (en) 2017-05-24 2018-11-28 Dompé farmaceutici S.p.A. Neurotrophins for use in the treatment of hearing loss
CN108456681B (zh) * 2018-03-26 2019-10-11 江苏中新医药有限公司 高效表达重组人神经生长因子的基因组合
US20210079053A1 (en) 2018-04-27 2021-03-18 Chiesi Farmaceutici Spa Production of nerve growth factor (ngf) and of muteins thereof
CN112334151A (zh) * 2018-06-29 2021-02-05 学校法人同志社 包含恩利卡生的制剂
JP2022502359A (ja) 2018-09-17 2022-01-11 キエージ・フアルマチエウテイチ・エツセ・ピ・ア 皮膚科障害の処置のための薬剤
IT201900014646A1 (it) * 2019-08-12 2021-02-12 Consiglio Nazionale Ricerche Peptide neurotrofico resistente alle proteasi per il trattamento terapeutico di patologie neurodegenerative e/o cutanee
CA3147828A1 (en) * 2019-09-17 2021-03-25 Bruno Pietro Imbimbo Agent for use in treatment or prevention of ophthalmic disorders
IL302317A (en) 2020-10-28 2023-06-01 Dompe Farm Spa Pharmaceutical packaging including polypropylene containers and aqueous formulations of NGF packed in them
EP4039269A1 (en) 2021-02-05 2022-08-10 Dompe' Farmaceutici S.P.A. Ngf isoform for use in the treatment of ocular pathologies
IL307622A (en) 2021-04-13 2023-12-01 Domp? Farm S P A Treatment of neuropathic corneal pain with NGF
EP4311554A1 (en) 2022-07-29 2024-01-31 Dompé farmaceutici S.p.a. Combination for use in ophthalmology
EP4316505A1 (en) 2022-08-05 2024-02-07 Dompé farmaceutici S.p.a. Intranasal administration of ngf for the treatment of sensorineural hearing loss
EP4342485A1 (en) 2022-09-23 2024-03-27 Dompe' Farmaceutici S.P.A. Ngf for the treatment of spasticity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4139000A1 (de) * 1991-11-27 1993-06-03 Boehringer Mannheim Gmbh Verfahren zur gentechnologischen herstellung von biologisch aktivem ss-ngf
ES2213861T3 (es) 1998-10-09 2004-09-01 Scil Proteins Gmbh Procedimiento de obtencion de ngf-beta activa.
US20030040082A1 (en) 2001-02-16 2003-02-27 Mark Tuszynski Mutant pro-neurotrophin with improved activity
US7507799B2 (en) 2001-05-25 2009-03-24 Cornell Research Foundation, Inc. High affinity ligand for p75 neurotrophin receptor
DE10360483B4 (de) 2003-12-22 2007-11-15 Scil Proteins Gmbh Expressionsvektor und dessen Verwendung
ES2315842T3 (es) 2004-01-19 2009-04-01 Nsgene A/S Celulas terapeuticas humanas que secretan factor de crecimiento nervioso.
US20080050776A1 (en) 2006-05-26 2008-02-28 Kenneth Neet Stable mutated pro nerve growth factors
CN101260398B (zh) * 2007-03-07 2013-06-05 舒泰神（北京）生物制药股份有限公司 神经生长因子基因定位改造动物及其制备方法和应用
ES2657344T3 (es) * 2011-12-19 2018-03-02 Wacker Chemie Ag Nuevos mutantes de proNGF y usos de los mismos en la producción de beta-NGF

Also Published As

Publication number Publication date
EP2672984B1 (en) 2015-05-27
SG11201402585PA (en) 2014-10-30
SG10201605028VA (en) 2016-07-28
MX2014007317A (es) 2014-11-25
CA2859262A1 (en) 2013-06-27
MX353074B (es) 2017-12-19
CY1119926T1 (el) 2018-12-12
NZ627054A (en) 2015-06-26
HUE027245T2 (en) 2016-10-28
US9617322B2 (en) 2017-04-11
ES2545701T3 (es) 2015-09-15
KR20140103318A (ko) 2014-08-26
WO2013092776A1 (en) 2013-06-27
US20150087020A1 (en) 2015-03-26
US10308694B2 (en) 2019-06-04
KR101837802B1 (ko) 2018-03-12
JP6622683B2 (ja) 2019-12-18
HRP20150900T1 (hr) 2015-10-09
IL233137A0 (en) 2014-07-31
CN104203264B (zh) 2018-08-28
BR112014014913A2 (pt) 2017-06-13
HK1202055A1 (en) 2015-09-18
EP2907521B1 (en) 2017-11-22
HRP20180307T1 (hr) 2018-03-23
AU2012357052B2 (en) 2015-06-25
CY1117016T1 (el) 2017-04-05
AU2012357052A1 (en) 2014-07-24
SI2907521T1 (en) 2018-03-30
EP2672984A1 (en) 2013-12-18
JP2017071611A (ja) 2017-04-13
PL2907521T3 (pl) 2018-04-30
RS54220B1 (en) 2015-12-31
US20200031893A1 (en) 2020-01-30
KR20160120788A (ko) 2016-10-18
JP2019006781A (ja) 2019-01-17
SI2672984T1 (sl) 2015-11-30
ES2657344T3 (es) 2018-03-02
MX370861B (es) 2020-01-08
SMT201500201B (it) 2015-10-30
US20160244496A1 (en) 2016-08-25
PT2672984E (pt) 2015-10-01
BR112014014913B1 (pt) 2020-12-01
EA201491155A1 (ru) 2015-01-30
PT2907521T (pt) 2018-02-22
DK2907521T3 (en) 2018-03-05
TR201802360T4 (tr) 2018-03-21
EA031333B1 (ru) 2018-12-28
JP6039146B2 (ja) 2016-12-07
PL2672984T3 (pl) 2015-10-30
LT2907521T (lt) 2018-05-10
JP2015501828A (ja) 2015-01-19
CN104203264A (zh) 2014-12-10
ZA201403753B (en) 2015-11-25
DK2672984T3 (en) 2015-08-24
EP2907521A1 (en) 2015-08-19
CN109400693A (zh) 2019-03-01
JP2019011330A (ja) 2019-01-24
HUE036265T2 (hu) 2018-06-28
RS56893B1 (sr) 2018-04-30
CA2859262C (en) 2021-04-06

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