NO2017015I2 - Kombinasjon avNεB29-Nα-(HOOC(CH2)14CO)-γ-Glu)des(B30)-humant insulin og Arg34Lys26(Nε-(γ-glutamyl(Nα-heksadekanoyl)))-GLP-1(7-37) - Google Patents

Kombinasjon avNεB29-Nα-(HOOC(CH2)14CO)-γ-Glu)des(B30)-humant insulin og Arg34Lys26(Nε-(γ-glutamyl(Nα-heksadekanoyl)))-GLP-1(7-37)

Info

Publication number
NO2017015I2
NO2017015I2 NO2017015C NO2017015C NO2017015I2 NO 2017015 I2 NO2017015 I2 NO 2017015I2 NO 2017015 C NO2017015 C NO 2017015C NO 2017015 C NO2017015 C NO 2017015C NO 2017015 I2 NO2017015 I2 NO 2017015I2
Authority
NO
Norway
Prior art keywords
nεb29
arg34lys26
hexadecanoyl
hooc
glutamyl
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NO2017015C
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English (en)
Norwegian (no)
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NO2017015I1 (no
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Novo Nordisk As
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Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO2017015I1 publication Critical patent/NO2017015I1/no
Publication of NO2017015I2 publication Critical patent/NO2017015I2/no

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
NO2017015C 2007-11-16 2017-04-21 Kombinasjon avNεB29-Nα-(HOOC(CH2)14CO)-γ-Glu)des(B30)-humant insulin og Arg34Lys26(Nε-(γ-glutamyl(Nα-heksadekanoyl)))-GLP-1(7-37) NO2017015I2 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07120880 2007-11-16
PCT/EP2008/065601 WO2009063072A2 (en) 2007-11-16 2008-11-14 Pharmaceutical compositions containing insulin and an insulinotropic peptide

Publications (2)

Publication Number Publication Date
NO2017015I1 NO2017015I1 (no) 2017-04-21
NO2017015I2 true NO2017015I2 (no) 2017-04-21

Family

ID=40639234

Family Applications (1)

Application Number Title Priority Date Filing Date
NO2017015C NO2017015I2 (no) 2007-11-16 2017-04-21 Kombinasjon avNεB29-Nα-(HOOC(CH2)14CO)-γ-Glu)des(B30)-humant insulin og Arg34Lys26(Nε-(γ-glutamyl(Nα-heksadekanoyl)))-GLP-1(7-37)

Country Status (15)

Country Link
US (1) US8937042B2 (cg-RX-API-DMAC7.html)
EP (2) EP2597103B1 (cg-RX-API-DMAC7.html)
JP (2) JP5241849B2 (cg-RX-API-DMAC7.html)
CN (3) CN101861333A (cg-RX-API-DMAC7.html)
BR (1) BRPI0820535B8 (cg-RX-API-DMAC7.html)
CA (1) CA2705821A1 (cg-RX-API-DMAC7.html)
DK (1) DK2597103T3 (cg-RX-API-DMAC7.html)
ES (2) ES2612736T3 (cg-RX-API-DMAC7.html)
HU (2) HUE030383T2 (cg-RX-API-DMAC7.html)
MX (1) MX2010005245A (cg-RX-API-DMAC7.html)
NO (1) NO2017015I2 (cg-RX-API-DMAC7.html)
PL (2) PL2597103T3 (cg-RX-API-DMAC7.html)
PT (1) PT2597103T (cg-RX-API-DMAC7.html)
WO (1) WO2009063072A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201003019B (cg-RX-API-DMAC7.html)

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NO2017015I1 (no) 2017-04-21
CN107412742B (zh) 2022-03-15
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US8937042B2 (en) 2015-01-20
CA2705821A1 (en) 2009-05-22
ES2612736T3 (es) 2017-05-18
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