NO20092804L - Kondensert, substituert aminopyrrolidinderivat - Google Patents

Kondensert, substituert aminopyrrolidinderivat

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Publication number
NO20092804L
NO20092804L NO20092804A NO20092804A NO20092804L NO 20092804 L NO20092804 L NO 20092804L NO 20092804 A NO20092804 A NO 20092804A NO 20092804 A NO20092804 A NO 20092804A NO 20092804 L NO20092804 L NO 20092804L
Authority
NO
Norway
Prior art keywords
quinolone
formula
substituent
against gram
antibacterial
Prior art date
Application number
NO20092804A
Other languages
English (en)
Inventor
Hisashi Takahashi
Rie Miyauchi
Makoto Takemura
Hiroaki Inagaki
Satoshi Komoriya
Takahiro Kitamura
Takashi Odagiri
Toshifumi Tsuda
Kiyoshi Nakayama
Kenichi Yoshida
Masatoshi Nagamochi
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of NO20092804L publication Critical patent/NO20092804L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Det er tilveiebrakt et syntetisk antibakterielt kinolonmiddel med utmerkede egenskaper som medisin, som har sterk antibakteriell aktivitet ikke bare mot gramnegative bakterier, men også mot grampositive kokker, lav sensitivitet overfor antibakterielle kinolonmidler, og som oppviser høy sikkerhet og utmerket farmakokinetikk; en forbindelse representert ved formel (I) eller et salt derav eller et hydrat derav; nærmere bestemt et kinolonderivat med formel (I), hvor substituentene R6 og R7 sammen med karbonatomene som de er bundet til, danner en ringstruktur som kan inneholde et oksygenatom som et ringbestanddelatom, hvor ringstrukturen danner en 5-4-, 5-5- eller 5-6-kondensert, bisyklisk pyrrolidinylsubstituent, hvor substituenten er bundet til et kinolonmoderskjelett Q som inneholder en pyridobenzoksazinstruktur.
NO20092804A 2007-01-05 2009-08-04 Kondensert, substituert aminopyrrolidinderivat NO20092804L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007000667 2007-01-05
JP2007074991 2007-03-22
PCT/JP2007/075434 WO2008082009A2 (en) 2007-01-05 2007-12-28 Fused substituted aminopyrrolidine derivative

Publications (1)

Publication Number Publication Date
NO20092804L true NO20092804L (no) 2009-10-05

Family

ID=39522355

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092804A NO20092804L (no) 2007-01-05 2009-08-04 Kondensert, substituert aminopyrrolidinderivat

Country Status (25)

Country Link
US (2) US8618094B2 (no)
EP (2) EP2097400B1 (no)
JP (1) JP5197606B2 (no)
KR (1) KR101419085B1 (no)
AR (1) AR064753A1 (no)
AU (1) AU2007339692B2 (no)
BR (1) BRPI0720771A2 (no)
CA (1) CA2674369C (no)
CL (1) CL2008000026A1 (no)
CY (1) CY1114444T1 (no)
DK (1) DK2097400T3 (no)
ES (1) ES2428344T3 (no)
HK (1) HK1130056A1 (no)
IL (1) IL199694A (no)
MX (1) MX2009007291A (no)
MY (1) MY162052A (no)
NO (1) NO20092804L (no)
NZ (1) NZ577214A (no)
PE (1) PE20081631A1 (no)
PL (1) PL2097400T3 (no)
PT (1) PT2097400E (no)
RU (1) RU2443698C2 (no)
SI (1) SI2097400T1 (no)
TW (1) TWI409068B (no)
WO (1) WO2008082009A2 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2602253A4 (en) 2010-08-06 2014-01-01 Daiichi Sankyo Co Ltd CRYSTAL OF AN ANTIBACTERIAL CONNECTION
TW201444558A (zh) * 2013-03-15 2014-12-01 Melinta Therapeutics Inc 使用喹諾酮類抗生素治療淋病感染的方法
UA124879C2 (uk) 2016-02-12 2021-12-08 Сайтокінетікс, Інкорпорейтед Похідні тетрагідроізохіноліну
KR20220080176A (ko) * 2019-10-23 2022-06-14 타이젠 바이오테크놀러지 컴퍼니 리미티드 퀴놀론 카르복실산 유도체
CA3227204A1 (en) * 2021-07-22 2023-01-26 The Texas A&M University System Activated ferrate solutions and methods thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61282382A (ja) 1985-06-06 1986-12-12 Dainippon Pharmaceut Co Ltd フエニル置換１，８−ナフチリジン誘導体、そのエステルおよびその塩
EP0242789A3 (en) 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivates and processes for preparation thereof
JPH0676400B2 (ja) 1987-08-25 1994-09-28 大日本製薬株式会社 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
MY105136A (en) 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
JP2807277B2 (ja) 1988-08-31 1998-10-08 第一製薬株式会社 スピロ化合物
JPH0278659A (ja) * 1988-09-12 1990-03-19 Shionogi & Co Ltd アザビシクロアルカン類化合物
WO1994014794A1 (en) 1992-12-28 1994-07-07 Yoshitomi Pharmaceutical Industries, Ltd. 8-methoxyquinolonecarboxylic acid derivative
JPH06345261A (ja) 1993-04-16 1994-12-20 Daihen Corp 自動搬送装置の搬送用ハンド
PT812838E (pt) * 1994-02-04 2002-10-31 Dainippon Pharmaceutical Co Derivado de acido piridonacarboxilico substituido com o grupo amino biciclico seu ester seu sal e amina biciclica como seu intermediario
DE4435479A1 (de) 1994-10-04 1996-04-11 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
ATE411309T1 (de) * 1995-02-02 2008-10-15 Daiichi Sankyo Co Ltd Pyridonkarbonsaüre derivate und deren verwendung als antibakterielle wirkstoffe
AU6153096A (en) * 1995-06-06 1996-12-24 Abbott Laboratories Quinolizinone type compounds
JP4132155B2 (ja) * 1996-10-25 2008-08-13 第一三共株式会社 三環性アミン誘導体
EP1134219B1 (en) * 1998-11-24 2005-06-15 Daiichi Pharmaceutical Co., Ltd. Cycloalkyl-substituted aminomethylpyrrolidine derivatives
RU2276154C2 (ru) * 2000-11-24 2006-05-10 Мейдзи Сейка Кайся, Лтд. Производные карбапенема, применение их для изготовления фармацевтической композиции, фармацевтическая композиция на их основе и способ лечения и/или профилактики инфекционных заболеваний
WO2005049602A1 (en) * 2003-11-18 2005-06-02 Warner-Lambert Company Llc Quinolone antibacterial agents
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative

Also Published As

Publication number Publication date
PE20081631A1 (es) 2008-11-22
CL2008000026A1 (es) 2008-05-16
MX2009007291A (es) 2009-07-14
PL2097400T3 (pl) 2013-11-29
RU2009129975A (ru) 2011-02-10
JP5197606B2 (ja) 2013-05-15
DK2097400T3 (da) 2013-10-14
CY1114444T1 (el) 2016-08-31
IL199694A0 (en) 2010-04-15
AU2007339692A1 (en) 2008-07-10
EP2540715A1 (en) 2013-01-02
BRPI0720771A2 (pt) 2014-07-15
PT2097400E (pt) 2013-10-10
US20140142096A1 (en) 2014-05-22
US8618094B2 (en) 2013-12-31
KR101419085B1 (ko) 2014-07-15
WO2008082009A3 (en) 2008-12-11
AR064753A1 (es) 2009-04-22
TWI409068B (zh) 2013-09-21
TW200836733A (en) 2008-09-16
IL199694A (en) 2013-08-29
EP2097400A2 (en) 2009-09-09
ES2428344T3 (es) 2013-11-07
RU2443698C2 (ru) 2012-02-27
EP2097400B1 (en) 2013-07-03
NZ577214A (en) 2011-11-25
CA2674369C (en) 2012-04-03
JP2010515663A (ja) 2010-05-13
MY162052A (en) 2017-05-31
WO2008082009A2 (en) 2008-07-10
CA2674369A1 (en) 2008-07-10
US20120108582A1 (en) 2012-05-03
HK1130056A1 (en) 2009-12-18
US20130029977A9 (en) 2013-01-31
AU2007339692B2 (en) 2012-01-19
SI2097400T1 (sl) 2013-10-30
KR20090096618A (ko) 2009-09-11

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