NO20083813L - Nitrogenholdig heterocyklisk derivat, og farmasoytisk middel omfattende derivatet som aktiv bestanddel - Google Patents
Nitrogenholdig heterocyklisk derivat, og farmasoytisk middel omfattende derivatet som aktiv bestanddelInfo
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- NO20083813L NO20083813L NO20083813A NO20083813A NO20083813L NO 20083813 L NO20083813 L NO 20083813L NO 20083813 A NO20083813 A NO 20083813A NO 20083813 A NO20083813 A NO 20083813A NO 20083813 L NO20083813 L NO 20083813L
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- C—CHEMISTRY; METALLURGY
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- A61P17/06—Antipsoriatics
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P37/02—Immunomodulators
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- A61P37/08—Antiallergic agents
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Otolaryngology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
Abstract
En forbindelse representert ved den generelle formel (I), et salt eller N-oksyd av forbindelsen, et solvat av forbindelsen. saltet eller N-oksydet, eller et prodrug av forbindelsen, saltet, N-oksydet eller solvatet, som kan binde spesifikt til CCR5 og derfor er anvendbar for forebygging og/eller behandling av en CCR5-assosiert sykdom, slik som inflammatorisk sykdom (f.eks. astma, nefritt, nefropati, hepatitt, artritt, revmatoid artritt, rhinitt, konjunktivitt, ulcerøs kolitt), en immunmediert sykdom (f eks. autoimmun sykdom, rejeksjon etter organtransplantasjon, immunsuppresjon, psoriasis, multippel sklerose), en infeksiøs sykdom (feks. infeksjon med humant immunsviktvirus, ervervet immunsviktsyndrom), en allergisk sykdom (feks. atopisk dermatitt, urticaria, allergisk bronkopulmonal aspergillose, allergisk eosinofil gastroenteritt), suppresjon av ischemi-reperfusjonsskade, akutt respiratorisk syndrom, sjokk forbundet med en bakteriell infeksjon, diabetes, cancermetastase eller lignende. hvori hvert symbol er som definert i beskrivelsen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006066451 | 2006-03-10 | ||
PCT/JP2007/054684 WO2007105637A1 (ja) | 2006-03-10 | 2007-03-09 | 含窒素複素環誘導体およびそれらを有効成分とする薬剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20083813L true NO20083813L (no) | 2008-12-10 |
Family
ID=38509460
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20083813A NO20083813L (no) | 2006-03-10 | 2008-09-08 | Nitrogenholdig heterocyklisk derivat, og farmasoytisk middel omfattende derivatet som aktiv bestanddel |
Country Status (15)
Country | Link |
---|---|
US (1) | US8003642B2 (no) |
EP (1) | EP1995246A4 (no) |
JP (1) | JPWO2007105637A1 (no) |
KR (1) | KR20090008217A (no) |
CN (1) | CN101443322A (no) |
AU (1) | AU2007225836A1 (no) |
BR (1) | BRPI0708731A2 (no) |
CA (1) | CA2644368A1 (no) |
EA (1) | EA200870344A1 (no) |
MA (1) | MA30294B1 (no) |
MX (1) | MX2008011414A (no) |
NO (1) | NO20083813L (no) |
RU (1) | RU2008140144A (no) |
WO (1) | WO2007105637A1 (no) |
ZA (1) | ZA200807767B (no) |
Families Citing this family (53)
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CA2517888C (en) | 2003-03-14 | 2012-05-01 | Ono Pharmaceutical Co., Ltd. | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient |
TW200600086A (en) * | 2004-06-05 | 2006-01-01 | Astrazeneca Ab | Chemical compound |
TWI400232B (zh) | 2004-09-13 | 2013-07-01 | Ono Pharmaceutical Co | 含氮雜環衍生物及以該含氮雜環衍生物為有效成分之藥劑 |
AU2006268406C1 (en) | 2005-07-09 | 2011-02-24 | Astrazeneca Ab | Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes |
HUE030235T2 (en) | 2005-12-13 | 2017-04-28 | Incyte Holdings Corp | Heteroaryl-substituted pyrrolo [2,3-b] pyridines and pyrrolo [2,3-b] pyrimidines as Janus kinase inhibitors |
CA2644368A1 (en) | 2006-03-10 | 2007-09-20 | Ono Pharmaceutical Co., Ltd. | Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient |
CL2007003061A1 (es) * | 2006-10-26 | 2008-08-01 | Astrazeneca Ab | Compuestos derivados de 3,5-dioxi-benzamida; proceso de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar una enfermedad mediada a traves de glk, tal como la diabetes tipo 2. |
JP2010519216A (ja) * | 2007-02-15 | 2010-06-03 | ファイザー・リミテッド | Ccr5拮抗薬のための医薬組成物および方法 |
EP3070090B1 (en) | 2007-06-13 | 2018-12-12 | Incyte Holdings Corporation | Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile |
ES2526966T3 (es) | 2008-06-05 | 2015-01-19 | Glaxo Group Limited | Compuestos novedosos |
WO2009147188A1 (en) | 2008-06-05 | 2009-12-10 | Glaxo Group Limited | Benzpyrazol derivatives as inhibitors of pi3 kinases |
ATE552255T1 (de) | 2008-06-05 | 2012-04-15 | Glaxo Group Ltd | 4-aminoindazole |
AU2009278929B2 (en) * | 2008-08-04 | 2012-07-05 | Astrazeneca Ab | Pyrazolo [3,4] pyrimidin-4-yl derivatives and their uses to treat diabetes and obesity |
CL2009001884A1 (es) * | 2008-10-02 | 2010-05-14 | Incyte Holdings Corp | Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco. |
GB0902406D0 (en) | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Crystalline polymorphic form |
GB0902434D0 (en) | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Chemical process |
JP5656880B2 (ja) | 2009-03-09 | 2015-01-21 | グラクソ グループ リミテッドGlaxo Group Limited | Pi3キナーゼの阻害剤としての4−オキサジアゾール−2−イル−インダゾール |
AR076220A1 (es) | 2009-04-09 | 2011-05-26 | Astrazeneca Ab | Derivados de pirazol [4,5 - e] pirimidina |
AR076221A1 (es) * | 2009-04-09 | 2011-05-26 | Astrazeneca Ab | Derivado de pirazol [4,5-e] pirimidina y su uso para tratar diabetes y obesidad |
AU2010243613B2 (en) | 2009-04-30 | 2015-05-07 | Glaxo Group Limited | Oxazole substituted indazoles as PI3-kinase inhibitors |
EA020494B1 (ru) | 2009-05-22 | 2014-11-28 | Инсайт Корпорейшн | 3-[4-(7H-ПИРРОЛО[2,3-d]ПИРИМИДИН-4-ИЛ)-1H-ПИРАЗОЛ-1-ИЛ]ОКТАН- ИЛИ ГЕПТАННИТРИЛ КАК JAK-ИНГИБИТОРЫ |
AR076794A1 (es) | 2009-05-22 | 2011-07-06 | Incyte Corp | Derivados de n-(hetero)aril-pirrolidina de pirazol-4-il-pirrolo [2,3-d]pirimidinas y pirrol-3-il-pirrolo [2,3-d ]pirimidinas como inhibidores de la quinasa janus y composiciones farmaceuticas que los contienen |
AR078012A1 (es) * | 2009-09-01 | 2011-10-05 | Incyte Corp | Derivados heterociclicos de las pirazol-4-il- pirrolo (2,3-d) pirimidinas como inhibidores de la quinasa janus |
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CN104169425A (zh) | 2011-03-09 | 2014-11-26 | 理查德·G·佩斯泰尔 | 前列腺癌细胞系、遗传标志及其用途 |
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2007
- 2007-03-09 CA CA002644368A patent/CA2644368A1/en not_active Abandoned
- 2007-03-09 AU AU2007225836A patent/AU2007225836A1/en not_active Abandoned
- 2007-03-09 KR KR1020087024728A patent/KR20090008217A/ko not_active Application Discontinuation
- 2007-03-09 MX MX2008011414A patent/MX2008011414A/es not_active Application Discontinuation
- 2007-03-09 RU RU2008140144/04A patent/RU2008140144A/ru not_active Application Discontinuation
- 2007-03-09 EA EA200870344A patent/EA200870344A1/ru unknown
- 2007-03-09 CN CNA2007800167421A patent/CN101443322A/zh active Pending
- 2007-03-09 BR BRPI0708731-4A patent/BRPI0708731A2/pt not_active IP Right Cessation
- 2007-03-09 WO PCT/JP2007/054684 patent/WO2007105637A1/ja active Application Filing
- 2007-03-09 EP EP07738169A patent/EP1995246A4/en not_active Withdrawn
- 2007-03-09 JP JP2008505116A patent/JPWO2007105637A1/ja not_active Withdrawn
- 2007-03-09 US US12/282,464 patent/US8003642B2/en not_active Expired - Fee Related
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2008
- 2008-09-08 NO NO20083813A patent/NO20083813L/no not_active Application Discontinuation
- 2008-09-09 ZA ZA200807767A patent/ZA200807767B/xx unknown
- 2008-09-29 MA MA31263A patent/MA30294B1/fr unknown
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US20090131403A1 (en) | 2009-05-21 |
WO2007105637A1 (ja) | 2007-09-20 |
KR20090008217A (ko) | 2009-01-21 |
EP1995246A1 (en) | 2008-11-26 |
CN101443322A (zh) | 2009-05-27 |
EP1995246A4 (en) | 2010-11-17 |
CA2644368A1 (en) | 2007-09-20 |
MX2008011414A (es) | 2008-09-22 |
BRPI0708731A2 (pt) | 2011-06-07 |
US8003642B2 (en) | 2011-08-23 |
RU2008140144A (ru) | 2010-04-20 |
ZA200807767B (en) | 2009-08-26 |
JPWO2007105637A1 (ja) | 2009-07-30 |
MA30294B1 (fr) | 2009-03-02 |
AU2007225836A1 (en) | 2007-09-20 |
EA200870344A1 (ru) | 2009-04-28 |
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