NO20082934L - Antivirale nukleotider - Google Patents

Antivirale nukleotider

Info

Publication number
NO20082934L
NO20082934L NO20082934A NO20082934A NO20082934L NO 20082934 L NO20082934 L NO 20082934L NO 20082934 A NO20082934 A NO 20082934A NO 20082934 A NO20082934 A NO 20082934A NO 20082934 L NO20082934 L NO 20082934L
Authority
NO
Norway
Prior art keywords
formula
methods
antiviral nucleotides
antiviral
nucleotides
Prior art date
Application number
NO20082934A
Other languages
English (en)
Inventor
Keshab Sarma
Byoung-Kwon Chun
Jeremy Clark
Peiyuan Wang
Original Assignee
Gilead Pharmasset Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37608355&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20082934(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Pharmasset Llc filed Critical Gilead Pharmasset Llc
Publication of NO20082934L publication Critical patent/NO20082934L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

Forbindelser som har formelen I hvori R1 er som heri definert er Hepatitt C virus NS5b polymerase-inhibitorer. Videre omtalt er blandinger og metoder for inhibering av hepatitt-replikasjon og fremgangsmåter for fremstilling av forbindelser med formel I.
NO20082934A 2005-12-09 2008-06-30 Antivirale nukleotider NO20082934L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74931905P 2005-12-09 2005-12-09
PCT/EP2006/069060 WO2007065829A1 (en) 2005-12-09 2006-11-29 Antiviral nucleosides

Publications (1)

Publication Number Publication Date
NO20082934L true NO20082934L (no) 2008-09-02

Family

ID=37608355

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082934A NO20082934L (no) 2005-12-09 2008-06-30 Antivirale nukleotider

Country Status (25)

Country Link
US (1) US7754699B2 (no)
EP (1) EP1957510A1 (no)
JP (2) JP4979710B2 (no)
KR (1) KR101238461B1 (no)
CN (1) CN101336247B (no)
AR (1) AR056850A1 (no)
AU (1) AU2006324098C1 (no)
BR (1) BRPI0619563A2 (no)
CA (1) CA2632626C (no)
CR (1) CR10136A (no)
EC (1) ECSP088518A (no)
GT (1) GT200800095A (no)
HN (1) HN2006041184A (no)
IL (1) IL192002A0 (no)
MA (1) MA30057B1 (no)
MY (1) MY150667A (no)
NO (1) NO20082934L (no)
NZ (1) NZ568909A (no)
PE (1) PE20071131A1 (no)
RU (1) RU2422454C2 (no)
TW (1) TWI394759B (no)
UA (1) UA91255C2 (no)
UY (1) UY30004A1 (no)
WO (1) WO2007065829A1 (no)
ZA (1) ZA200804958B (no)

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US8618076B2 (en) 2009-05-20 2013-12-31 Gilead Pharmasset Llc Nucleoside phosphoramidates
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Also Published As

Publication number Publication date
WO2007065829A1 (en) 2007-06-14
JP2009518354A (ja) 2009-05-07
CN101336247A (zh) 2008-12-31
HN2006041184A (es) 2010-09-10
CA2632626E (en) 2007-06-14
TWI394759B (zh) 2013-05-01
AU2006324098C1 (en) 2011-12-08
JP4979710B2 (ja) 2012-07-18
AU2006324098A1 (en) 2007-06-14
CR10136A (es) 2008-11-18
KR20080079671A (ko) 2008-09-01
KR101238461B1 (ko) 2013-03-05
GT200800095A (es) 2009-10-08
CA2632626C (en) 2011-10-11
US7754699B2 (en) 2010-07-13
JP2012097098A (ja) 2012-05-24
MA30057B1 (fr) 2008-12-01
ECSP088518A (es) 2008-09-29
AU2006324098B2 (en) 2011-02-24
AR056850A1 (es) 2007-10-24
UY30004A1 (es) 2007-06-29
IL192002A0 (en) 2008-12-29
RU2422454C2 (ru) 2011-06-27
CA2632626A1 (en) 2007-06-14
RU2008127750A (ru) 2010-01-20
ZA200804958B (en) 2009-05-27
PE20071131A1 (es) 2007-11-30
CN101336247B (zh) 2013-01-23
TW200745151A (en) 2007-12-16
UA91255C2 (uk) 2010-07-12
EP1957510A1 (en) 2008-08-20
NZ568909A (en) 2011-10-28
US20070197463A1 (en) 2007-08-23
MY150667A (en) 2014-02-28
BRPI0619563A2 (pt) 2011-10-04

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